产品简要
公司名称 :
NKMAX
产品类型 :
抗体
产品名称 :
人类RAB5A抗体
目录 :
ATGA0519
规格 :
50微升
价格 :
190美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
3A4
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名 :
人类RAB5A抗体
目录号(SKU号) :
ATGA0519
NCBI :
NP_004153
描述 :
Rab5a is a member of the RAS oncogene family. Rab5a is a small GTPase localized to the plasma membrane and early endosomes. It is a crucial regulatory component of the endocytic pathway. Activation of Rab5a is mediated by GDP-GTP exchange factors (GEFs) that generate the Rab5-GTP complex.
别称 :
RAB5A member RAS oncogene family, Ras-related protein Rab-5A, RAS-associated protein RAB5A, RAB5
浓度 :
1mg/ml (determined by BCA assay)
配方 :
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Bucci C, et al., (1992) Cell 70 (5): 715-28;;Seachrist JL, et al., (2002) J. Biol. Chem. 277 (1): 679-85
ab宿主 :
小鼠
抗体亚型 :
IgG2b kappa
免疫原 :
重组人类Rab5a(1-215aa)纯化来自大肠杆菌
应用 :
酶联免疫吸附测定, 免疫印迹, 免疫细胞化学/IF
IF Comment And Pic :
ICC/IF analysis of Rab5a in U87MG cells. The cell was stained with ATGA0519 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).
WB Comment and Pic :
The cell lysates(40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human Rab5a antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;; Lane 1.: 293T cell lysate;; Lane 2.: Rab5a Transfected 293T cell lysate;;
反应对象 :
人类
克隆编号 :
3A4
Ab用途 :
The antibody has been tested by ELISA, Western blot analysis and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
抗原物种 :
人类
基因类别 :
神经科学
Additional Comment Only :
This product was produced from tissue culture supernatant.
共轭 :
未共轭
Clonality Mono VS Poly :
单克隆
Ab纯化评论 :
By protein-A affinity chromatography
产品类型名 :
单克隆抗体
UniProt No. :
P20339
内部搜索条款 :
Rab5a, ATGA0519-10微克, ATGA0519-20微克, ATGA0519-50微克, ATGA0519-100微克, ATGA0519-250微克, ATGA0519-500微克, ATGA0519-1毫克, ATGA0519-10, ATGA0519-20, ATGA0519-50, ATGA0519-100, ATGA0519-250, ATGA0519-500, ATGA0519-1
References with this Product :
Gorji-Bahri G, et al. RAB5A is associated with genes involved in exosome secretion: Integration of bioinformatics analysis and experimental validation. (J Cell Biochem. 2021){https://pubmed.ncbi.nlm.nih.gov/33225526/};;Gorji-Bahri G, et al. RAB5A effect on metastasis of hepatocellular carcinoma cell line via altering the pro-invasive content of exosomes. (Exp Mol Pathol. 2021){https://pubmed.ncbi.nlm.nih.gov/33831402/};;Polla DL, et al. Biallelic variants in TMEM222 cause a new autosomal recessive neurodevelopmental disorder. (Genet Med. 2021){https://pubmed.ncbi.nlm.nih.gov/33824500/};;Nanou A, et al. Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis. (Cell Rep. 2021){https://pubmed.ncbi.nlm.nih.gov/34038728/};;Huang HW, Ryoo HD. Drosophila fabp is required for light-dependent Rhodopsin-1 clearance and photoreceptor survival. (PLoS Genet. 2021){https://pubmed.ncbi.nlm.nih.gov/34714826/};;Patel M, et al. Spatial expression of IKK-alpha is associated with a differential mutational landscape and survival in primary colorectal cancer. (Br J Cancer. 2022){https://pubmed.ncbi.nlm.nih.gov/35173303/};;Tang Y, et al. The effect of drug loading and multiple administration on the protein corona formation and brain delivery property of PEG-PLA nanoparticles. (Acta Pharm Sin B. 2022){https://pubmed.ncbi.nlm.nih.gov/35847504/}
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司,制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。