产品简要
公司名称 :
NKMAX
产品类型 :
抗体
产品名称 :
人类TLR7抗体
目录 :
ATGA0530
规格 :
50微升
价格 :
190美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4F4
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 流式细胞仪
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名 :
人类TLR7抗体
目录号(SKU号) :
ATGA0530
NCBI :
NP_057646
描述 :
TLR7 is one of toll-like receptors which are type I transmembrane proteins involved in innate immunity byrecognizing microbial conserved structures. These proteins are characterized by multiple copies of leucine richrepeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain, and act through adaptormolecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Human TLR7(hTLR7) is predominantly expressed in lung, placenta and spleen and hTLR7, 8 genes are located on the sexchromosome X. hTLR7 may play an important role in detecting and combating viral infections.
别称 :
toll-like receptor 7, PRO285, UNQ248, tlr 7
浓度 :
1mg/ml (determined by BCA assay)
配方 :
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Lee J., et al. (2003) Proc. Natl. Acad. Sci. USA. 100:6646-6651.;; Crozat K., et al. (2004) Proc. Natl. Acad. Sci. USA. 101:6835-6836.;; Muzio M., et al. (1998) J. Exp. Med. 187:2097-2101.;; Horng T., et al. (2002) Nature 420:329-333.;;
ab宿主 :
小鼠
抗体亚型 :
IgG1 kappa
免疫原 :
重组人类TLR7(451-500aa)纯化来自大肠杆菌
应用 :
酶联免疫吸附测定, 免疫印迹, 流式细胞仪
WB Comment and Pic :
The recombinant protein (50ng) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human TLR7 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;;Lane 1.: Recombinant human TLR7 protein;;
反应对象 :
人类
克隆编号 :
4F4
Ab用途 :
The antibody has been tested by ELISA, Western blot and FACS analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
FACS Comment and Pic :
Flow cytometry analysis of TLR7 in THP-1 cells. The cell was stained with ATGA0530 at 2-5ug for 1x10^6cells (red). A Goat anti mouse IgG (Alexa fluor 488) was used as the secondary antibody. Mouse monoclonal IgG was used as the isotype control (dark gray), cells without incubation with primary and secondary antibody was used as the negative control (light gray).
抗原物种 :
人类
基因类别 :
Epigenetics and Nuclear Signaling
Additional Comment Only :
This product was produced from tissue culture supernatant.
共轭 :
未共轭
Clonality Mono VS Poly :
单克隆
Ab纯化评论 :
By protein-A affinity chromatography
产品类型名 :
单克隆抗体
UniProt No. :
Q9NYK1
内部搜索条款 :
TLR7, ATGA0530-10微克, ATGA0530-20微克, ATGA0530-50微克, ATGA0530-100微克, ATGA0530-250微克, ATGA0530-500微克, ATGA0530-1毫克, ATGA0530-10, ATGA0530-20, ATGA0530-50, ATGA0530-100, ATGA0530-250, ATGA0530-500, ATGA0530-1
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司，制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。