产品简要
公司名称 :
NKMAX
产品类型 :
抗体
产品名称 :
表皮生长因子受体抗体
目录 :
ATGA0541
规格 :
50微升
价格 :
190美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
AT2H8
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名 :
表皮生长因子受体抗体
目录号(SKU号) :
ATGA0541
NCBI :
NP_005219
描述 :
Epidermal growth factor receptor (EGFR) is a 170 kDa membrane protein first identified as a bindingpartner of EGF. Also, EGFR phosphorylated itself (autophosphorylation) in response to EGF treatment. Theoverexpression of EGFR in various epithelial tumors was widely reported and it has been substantiated thatderegulation of EGFR itself and its signaling pathways an important role in human cancers.
别称 :
ERBB, ERBB1, Epidermal growth factor receptor, HER1, PIG61, epidermal growth factor receptor,Urogastrone, Proto-oncogene c-ErbB-1, Oncogene ERBB, Cell proliferation inducing protein 61, Cellgrowth inhibiting protein 40, Avian erythroblastic leukemia viral (verbb) oncogene homolog
浓度 :
1mg/ml (determined by BCA assay)
配方 :
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Cohen S, (1964) Nat Cancer Inst Monogr, 13: 13-27.;;Toyoda H, et al. (1995) J Biol Chem, 270: 7495-500.;;Carpenter G, et al. (1978) Nature,276: 409-10.
ab宿主 :
小鼠
抗体亚型 :
IgG2b kappa
免疫原 :
重组人类表皮生长因子受体(424-605aa)纯化来自大肠杆菌
应用 :
酶联免疫吸附测定, 免疫印迹, 免疫细胞化学/IF
IF Comment And Pic :
ICC/IF analysis of EGFR in HeLa cells. The cell was stained with ATGA0541 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).
WB Comment and Pic :
The cell lysate (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human EGFR antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;;Lane 1.: A431 cell lysate;;
反应对象 :
人类
克隆编号 :
AT2H8
Ab用途 :
The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
抗原物种 :
人类
基因类别 :
Cancer
Additional Comment Only :
This product was produced from tissue culture supernatant.
共轭 :
未共轭
Clonality Mono VS Poly :
单克隆
Ab纯化评论 :
By protein-A affinity chromatography
产品类型名 :
单克隆抗体
UniProt No. :
P00533
内部搜索条款 :
表皮生长因子受体, ATGA0541-10微克, ATGA0541-20微克, ATGA0541-50微克, ATGA0541-100微克, ATGA0541-250微克, ATGA0541-500微克, ATGA0541-1毫克, ATGA0541-10, ATGA0541-20, ATGA0541-50, ATGA0541-100, ATGA0541-250, ATGA0541-500, ATGA0541-1
References with this Product :
Tran AV, et al. Targeted and controlled drug delivery by multifunctional mesoporous silica nanoparticles with internal fluorescent conjugates and external polydopamine and graphene oxide layers. (Acta Biomater. 2018){https://pubmed.ncbi.nlm.nih.gov/29775731/};;Tran VA, et al. Multimodal Mesoporous Silica Nanocarriers for Dual Stimuli-Responsive Drug Release and Excellent Photothermal Ablation of Cancer Cells. (Int J Nanomedicine. 2020) {https://pubmed.ncbi.nlm.nih.gov/33116494/}
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司,制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。