产品简要
公司名称 :
NKMAX
产品类型 :
抗体
产品名称 :
NPM1
目录 :
ATGA0565
规格 :
100微升/50微升
价格 :
320/190美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
AT23F1
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
产品信息
目录代码 :
ATGA0565
产品名称 :
NPM1
产品类型 :
一抗
标价 :
320/190美元
克隆性 :
单克隆
宿主名称 :
小鼠
克隆 :
AT23F1
共轭标签 :
未共轭
抗体亚型 :
IgG1 kappa
产品描述 :
NPM1 is associated with nucleolar ribonucleoprotein structures and bind single-stranded and double-strandednucleic acids, but it binds preferentially G-Quadruplex forming nucleic acids. It is involved in the biogenesisof ribosomes and may assist small basic proteins in their transport to the nucleolus. Its regulation throughSUMOylation (by SENP3 and SENP5) is another facet of the proteins's regulation and cellular functions.It is located in the nucleolus, but it can be translocated to the nucleoplasm in case of serum starvation ortreatment with anticancer drugs. The protein is phosphorylated. Chromosomal aberrations involving NPM1 werefound in patients with non-Hodgkin lymphoma, acute promyelocytic leukemia, myelodysplastic syndrome, and acutemyelogenous leukemia. It has been found in the cytoplasm in patients with primary acute myelogenous leukemia.
交叉活性 :
人类
物种摘要 :
人类
背景 :
未共轭
免疫原 :
重组人类NPM1(1-294aa)纯化来自大肠杆菌
纯度 :
By protein-A affinity chromatography
包装 :
Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol
包装尺寸 :
100微升/50微升
浓度 :
1毫克/毫升
用途 :
The antibody has been tested by ELISA, Western blot, ICC/IF and FACS analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
应用摘要 :
酶联免疫吸附测定, 免疫印迹, 免疫细胞化学/IF, 流式细胞仪
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Maiguel D.A., et al.(2004) Mol cell Biol. 24: 3703-3711.;;Colombo E., et al. (2005) Mol cell Biol. 25: 8874-8886.;;
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
salesbio@atgenglobal.com
http://www.atgenglobal.com
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司,制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。