产品简要
公司名称 :
NKMAX
产品类型 :
抗体
产品名称 :
人类CTLA4抗体
目录 :
ATGA0572
规格 :
50微升
价格 :
190美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
AT4C8
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名 :
人类CTLA4抗体
目录号(SKU号) :
ATGA0572
NCBI :
NP_005205
描述 :
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4), also known as CD152, is a protein receptor that downregulates the immune system. CTLA4 is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Mutations in CTLA4 have been associated with insulin-dependent diabetes mellitus, Graves' disease, Hashimoto's thyroiditis, celiac disease and other autoimmune diseases.
别称 :
Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, CELIAC3, Celiac disease 3, Insulin-dependent diabetes mellitus 12, IDDM12, CD, GSE
浓度 :
1mg/ml (determined by BCA assay)
配方 :
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Dariavach. P., et al. (1988) Eur J Immunol 18(12): 1901-1905.;; Waterhouse. P., et al. (1995) Science 270(5238): 985-988.;; Magistrelli. G., et al. (1999) Eur J Immunol 29(11): 3596-3602.
ab宿主 :
小鼠
抗体亚型 :
IgG1 kappa
免疫原 :
重组人类CTLA4(36-161aa)纯化来自大肠杆菌
应用 :
酶联免疫吸附测定, 免疫印迹
WB Comment and Pic :
The tissue and cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CTLA4 antibody (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1.: Mouse liver tissue lysate;; Lane 2.: TF-1 cell lysate;; Lane 3.: HepG2 cell lysate;; Lane 4.: WiDr cell lysate;;
反应对象 :
人类
克隆编号 :
AT4C8
Ab用途 :
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
抗原物种 :
人类
基因类别 :
干细胞
共轭 :
未共轭
Clonality Mono VS Poly :
单克隆
Ab纯化评论 :
By protein-G affinity chromatography
产品类型名 :
单克隆抗体
UniProt No. :
P16410
内部搜索条款 :
CTLA4, ATGA0572-10微克, ATGA0572-20微克, ATGA0572-50微克, ATGA0572-100微克, ATGA0572-250微克, ATGA0572-500微克, ATGA0572-1毫克, ATGA0572-10, ATGA0572-20, ATGA0572-50, ATGA0572-100, ATGA0572-250, ATGA0572-500, ATGA0572-1
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司，制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。