蛋白

重组人类FKBP12/FKBP1A蛋白

ATGP0290

20微克

70美元

重组人类FKBP12/FKBP1A蛋白

1-108aa

ATGP0290

NP_463460.1

FK506 binding protein 1a, also known as FKBP12, belongs to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1, 4, 5-trisphosphate receptor. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. Recombinant human FKBP12, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

FKBP prolyl isomerase 1A, FKBP1, FK506 binding protein 1a 12kDa, PPIase FKBP1A, Rotamase, 12 kDa FKBP, FK506 binding protein 1, FK506 binding protein 1A 12kDa, Immunophilin FKBP12, FK506 binding protein T cell 12 kD, FK506 binding protein 12, FKBP 12, FKBP12 Exip3, FKBP12C, Peptidyl-prolyl cis-trans isomerase, PKCI2, PPIase, Protein kinase C inhibitor 2, calstabin 1, Rotamase

1毫克/毫升(由布拉德福德Bradford检测确定)

液体。 20mM三羟甲基氨基甲烷氯化氢缓冲液(pH值8.0)含100mM氯化钠, 1mM DTT, 10% 甘油

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Jayaraman T., et al. (1992). J Biol Chem. 267(14):9474-7;; Siekierka JJ., et al. (1990). J Biol Chem. 265(34):21011-5;;

> 95% by SDS-PAGE

Specific activity is > 800nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAPF-pNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin.

十二烷基磺酸钠-PAGE, 酶活性

人类

热休克蛋白

14.1 kDa (128aa) confirmed by MALDI-TOF

< 1 EU per 1ug of protein (determined by LAL method)

Specific activity is > 800 nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAPF-pNA per minute at 37C in Tris-HCl pH 8.0 using chymotrypsin.

MGVQVETISP GDGRTFPKRG QTCVVHYTGM LEDGKKFDSS RDRNKPFKFM LGKQEVIRGW EEGVAQMSVG QRAKLTISPD YAYGATGHPG IIPPHATLVF DVELLKLE

多聚组氨酸标签

大肠杆菌

重组蛋白

P62942

FKBP1a , FKBP12, FK506 binding protein 1a 12kDa, PPIase FKBP1A, Rotamase, FKBP1, PKC12, FK506 binding protein 1a, 12kDa 12 kDa FKBP, FK506 binding protein 1, FK506 binding protein 1A 12kDa, Immunophilin FKBP12, FK506 binding protein T cell 12 kD, FK506-binding protein 1A, FK506 binding protein 12, FKBP 12, FKBP 1A, FKBP12, FKBP12 Exip3, FKBP12C, Peptidyl-prolyl cis-trans isomerase, PKCI2, PPIase, Protein kinase C inhibitor 2.,ATGP0290-10ug,ATGP0290-20ug,ATGP0290-50ug,ATGP0290-100ug,ATGP0290-250ug,ATGP0290-500ug,ATGP0290-1mg,ATGP0290-10,ATGP0290-20,ATGP0290-50,ATGP0290-100,ATGP0290-250,ATGP0290-500,ATGP0290-1