蛋白

重组人类膜联蛋白Aa1/ANXA1蛋白

ATGP0291

4微克

105美元

重组人类膜联蛋白Aa1/ANXA1蛋白

1-346aa

ATGP0291

NP_000691.1

Annexin A1, also known as Lipocortin I, belongs to a family of Ca (2+) -dependent phospholipid binding proteins that are preferentially located on the cytosolic face of the plasma membrane. It promotes membrane fusion and is also involved in exocytosis. Since Annexin A1 has phospholipase A2 inhibitory activity to bind from two to four calcium ions with high affinity, this protein may have potential anti-inflammatory activity. The detection of this protein by immunocytochemical means reportedly provides a simple, highly sensitive and specific assay for diagnosis of hairy cell leukemia. Recombinant human Annexin A1 protein was expressed in E. coli and purified by using conventional chromatography.

Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin I, phospholipase A2 inhibitory protein, p35, Annexin Ac2-26, ANX1, LPC1

1毫克/毫升(由布拉德福德Bradford检测确定)

液体。 20mM三羟甲基氨基甲烷氯化氢缓冲液(pH值8.0)含100mM氯化钠, 1mM DTT, 10% 甘油

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Lim LH., et al. (2007). FASEB J. 21(4):968-75;; Kovacic RT., et al. (1991). Biochemistry. 30(37):9015-21;;

> 90% by SDS-PAGE

十二烷基磺酸钠-PAGE

人类

血清学

38.7 kDa (346aa) confirmed by MALDI-TOF

MAMVSEFLKQ AWFIENEEQE YVQTVKSSKG GPGSAVSPYP TFNPSSDVAA LHKAIMVKGV DEATIIDILT KRNNAQRQQI KAAYLQETGK PLDETLKKAL TGHLEEVVLA LLKTPAQFDA DELRAAMKGL GTDEDTLIEI LASRTNKEIR DINRVYREEL KRDLAKDITS DTSGDFRNAL LSLAKGDRSE DFGVNEDLAD SDARALYEAG ERRKGTDVNV FNTILTTRSY PQLRRVFQKY TKYSKHDMNK VLDLELKGDI EKCLTAIVKC ATSKPAFFAE KLHQAMKGVG TRHKALIRIM VSRSEIDMND IKAFYQKMYG ISLCQAILDE TKGDYEKILV ALCGGN

Non-Tagged

大肠杆菌

重组蛋白

P04083

Phospholipase A2 inhibitory protein, p35, LPC-1, LPC1, LPC 1, Lipocortin-I, LipocortinI, Lipocortin-1, Lipocortin1, Lipocortin I, Lipocortin 1, HGNC:533, Chromobindin-9, Chromobindin9, Chromobindin 9, Calpactin-II, CalpactinII, Calpactin-2, Calpactin2, Calpactin II, Calpactin 2, ANXA1 protein, ANXA1, ANXA 1, ANX1, ANX A1, ANX 1, Annexin-I, AnnexinI, AnnexinA1, Annexin-1, Annexin1, Annexin I, Annexin Ac2-26, Annexin Ac2 26, Annexin A1, Annexin 1, ATGP0291-10ug, ATGP0291-20ug, ATGP0291-50ug, ATGP0291-100ug, ATGP0291-250ug, ATGP0291-500ug, ATGP0291-1mg, ATGP0291-010, ATGP0291-020, ATGP0291-050, ATGP0291-100, ATGP0291-250, ATGP0291-500, ATGP0291-01M

Jung SH, et al. Integrative proteomic profiling of protein activity and interactions using protein arrays. (Mol Cell Proteomics. 2012){https://pubmed.ncbi.nlm.nih.gov/22843993/};;Jung SH, et al. Identification of transglutaminase 2 kinase substrates using a novel on-chip activity assay. (Biosens Bioelectron. 2016){https://pubmed.ncbi.nlm.nih.gov/27040940/};;Jung SH, et al. Systematic investigation of protein kinase A substrate proteins using on-chip protein kinase kinetic profiling. (Analyst. 2017){https://pubmed.ncbi.nlm.nih.gov/28536714/};;Vais H, et al. ER-luminal [Ca2+] regulation of InsP3 receptor gating mediated by an ER-luminal peripheral Ca2+-binding protein. (Elife. 2020){https://pubmed.ncbi.nlm.nih.gov/32420875/}