蛋白

重组人类MMAB蛋白

ATGP0677

20微克

80美元

重组人类MMAB蛋白

33-250aa

ATGP0677

AAH05054

MMAB is a protein that catalyzes the final step in the conversion of vitamin B (12) into adenosylcobalamin (AdoCbl), a vitamin B12 containing coenzyme for methylmalonyl-CoA mutase (MCM). Impaired MMAB activity leads to the inherited disorder vitamin B12 dependent methylmalonic aciduria linked to the cblB complementation group. Recombinant human MMAB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Methylmalonic aciduria (cobalamin deficiency) cblB type, ATR, ATP:cob(I)alamin adenosyltransferase, Methylmalonic aciduria (cobalamin deficiency) cblB type

1毫克/毫升(由布拉德福德Bradford检测确定)

液体。 20mM三羟甲基氨基甲烷氯化氢缓冲液(pH值7.5)含10% 甘油

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Gravel RA., et al. (2009) Mol Genet Metab. 98(3):278-84;; Edwards AM., et al (2004) J Biol Chem. 279(22):23646-53.;;

> 95% by SDS-PAGE

十二烷基磺酸钠-PAGE

人类

酶&蛋白酶

26.3 kDa (239aa) confirmed by MALDI-TOF

MGSSHHHHHH SSGLVPRGSH MQSRGPQGVE DGDRPQPSSK TPRIPKIYTK TGDKGFSSTF TGERRPKDDQ VFEAVGTTDE LSSAIGFALE LVTEKGHTFA EELQKIQCTL QDVGSALATP CSSAREAHLK YTTFKAGPIL ELEQWIDKYT SQLPPLTAFI LPSGGKISSA LHFCRAVCRR AERRVVPLVQ MGETDANVAK FLNRLSDYLF TLARYAAMKE GNQEKIYKKN DPSAESEGL

多聚组氨酸标签

大肠杆菌

重组蛋白

Q96EY8

MMAB, Methylmalonic aciduria (cobalamin deficiency) cblB type, ATR, ATP:cob(I)alamin adenosyltransferase, Methylmalonic aciduria (cobalamin deficiency) cblB type,ATGP0677-10ug,ATGP0677-20ug,ATGP0677-50ug,ATGP0677-100ug,ATGP0677-250ug,ATGP0677-500ug,ATGP0677-1mg,ATGP0677-10,ATGP0677-20,ATGP0677-50,ATGP0677-100,ATGP0677-250,ATGP0677-500,ATGP0677-1