蛋白

重组人类RPA2蛋白

ATGP0792

10微克

120美元

重组人类RPA2蛋白

1-270aa

ATGP0792

NP_002937

Replication Protein A (RPA) is a single stranded DNA binding protein. Human RPA is a heterotrimeric protein containing subunits of 14, 32 and 70kDa. This protein complex is highly conserved in eukaryotes and is essential in DNA replication, homologous recombination and nucleotide excision repair. The C-terminus of RPA2 can specfically intereact with the DNA repair enzyme uNG2 and repair factors XPA and Rad52, each of which functions in a different repair pathway. In addition, this protein binds specifically to the SH2 domain of Stat3 in vivo, and overexpression of RPA2 corresponds to the augmented growth factor-stimulated tyrosine phosphorylation and transcription activities of Stat3. Recombinant human RPA2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Replication protein A 32 kDa subunit, Replication protein A 32 kDa subunit, REPA2, RPA32, RPA32, RP-A p32, RP-A p34

0.5毫克/毫升(由布拉德福德Bradford检测确定)

液体。 20mM三羟甲基氨基甲烷氯化氢缓冲液(pH值8.0)含20% 甘油, 0.1M氯化钠, 2mM DTT

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Wang M., et al. (2000) Biochemistry. 39(21):6433-9. ;; Mer G., et al. (2000) Cell. 103(3):449-56.;;

> 90% by SDS-PAGE

十二烷基磺酸钠-PAGE

人类

Epigenomics (Transcription & Translation)

31.7 kDa (293aa) confirmed by MALDI-TOF

MWNSGFE SYGSSSYGGA GGYTQSPGGF GSPAPSQAEK KSRARAQHIV PCTISQLLSA TLVDEVFRIG NVEISQVTIV GIIRHAEKAP TNIVYKIDDM TAAPMDVRQW VDTDDTSSEN TVVPPETYVK VAGHLRSFQN KKSLVAFKIM PLEDMNEFTT HILEVINAHM VLSKANSQPS AGRAPISNPG MSEAGNFGGN SFMPANGLTV AQNQVLNLIK ACPRPEGLNF QDLKNQLKHM SVSSIKQAVD FLSNEGHIYS TVDDDHFKST DAE

多聚组氨酸标签

大肠杆菌

重组蛋白

P15927

RPA2, ATGP0792-10微克, ATGP0792-20微克, ATGP0792-50微克, ATGP0792-100微克, ATGP0792-250微克, ATGP0792-500微克, ATGP0792-1毫克, ATGP0792-10, ATGP0792-20, ATGP0792-50, ATGP0792-100, ATGP0792-250, ATGP0792-500, ATGP0792-1