蛋白

重组人类NPM1蛋白

ATGP1576

20微克

80美元

重组人类NPM1蛋白

1-294aa

ATGP1576

NP_002511.1

NPM1 is a phosphoprotein which moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in NPM1 are associated with acute myeloid leukemia. Recombinant human NPM1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Nucleophosmin, B23, NPM

0.5毫克/毫升(由布拉德福德Bradford检测确定)

液体。 20mM三羟甲基氨基甲烷氯化氢缓冲液(pH值8.0)含10% 甘油0.15M氯化钠, 1mM DTT

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Sagawa,F., et al. (2011) EMBO J. 30 (19), 3994-4005.;; Neubauer,A., et al. (2011) Exp. Hematol. 39 (10), 1030-1042.

> 85% by SDS-PAGE

十二烷基磺酸钠-PAGE

人类

Epigenomics (Transcription & Translation)

34.7 kDa (314aa) confirmed by MALDI-TOF

MEDSMDMDMS PLRPQNYLFG CELKADKDYH FKVDNDENEH QLSLRTVSLG AGAKDELHIV EAEAMNYEGS PIKVTLATLK MSVQPTVSLG GFEITPPVVL RLKCGSGPVH ISGQHLVAVE EDAESEDEEE EDVKLLSISG KRSAPGGGSK VPQKKVKLAA DEDDDDDDEE DDDEDDDDDD FDDEEAEEKA PVKKSIRDTP AKNAQKSNQN GKDSKPSSTP RSKGQESFKK QEKTPKTPKG PSSVEDIKAK MQASIEKGGS LPKVEAKFIN YVKNCFRMTD QEAIQDLWQW RKSL

多聚组氨酸标签

大肠杆菌

重组蛋白

P06748

NPM1, ATGP1576-10微克, ATGP1576-20微克, ATGP1576-50微克, ATGP1576-100微克, ATGP1576-250微克, ATGP1576-500微克, ATGP1576-1毫克, ATGP1576-10, ATGP1576-20, ATGP1576-50, ATGP1576-100, ATGP1576-250, ATGP1576-500, ATGP1576-1

Nakatomi K,et al. TLR4/MD-2 is a receptor for extracellular nucleophosmin 1. (Biomed Rep. 2021){https://pubmed.ncbi.nlm.nih.gov/33335727/}