产品简要
产品信息
产品类型 :
蛋白质
产品名 :
重组人类NHEJ1蛋白
区域 :
1-224aa
目录号(SKU号) :
ATGP1684
NCBI :
NP_079058
描述 :
Non-homologous end-joining factor 1, also known as NHEJ1, belongs to the XLF family. NHEJ1 was originally discovered as the protein mutated in five patients with growth retardation, microcephaly, and immunodeficiency. The protein is required for the non-homologous end joining (NHEJ) pathway of DNA repair. Patients with NHEJ1 mutations also have immunodeficiency due to a defect in V (D) J recombination, which utilizes NHEJ to promote immune system diversity. XLF interacts with DNA ligase IV and XRCC4 and is thought to be involved in the ligation step of NHEJ. Recombinant human NHEJ1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
别称 :
Non-homologous end-joining factor 1, XLF
浓度 :
0.5毫克/毫升(由布拉德福德Bradford检测确定)
配方 :
液体。 20mM三羟甲基氨基甲烷氯化氢缓冲液(pH值8.0)含0.1M氯化钠, 20% 甘油, 1mM DTT
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Buck D., et al. (2006) Cell. 124:287-299;; Ahnesorg P., et al. (2006) Cell. 124:301-313
纯度 :
> 90% by SDS-PAGE
应用 :
十二烷基磺酸钠-PAGE
抗原物种 :
人类
基因类别 :
Epigenomics (Transcription & Translation)
分子量 :
27.8 kDa (247aa) confirmed by MALDI-TOF
Bioassay Procedure :
MGSSHHHHHH SSGLVPRGSH MGSMEELEQG LLMQPWAWLQ LAENSLLAKV FITKQGYALL VSDLQQVWHE QVDTSVVSQR AKELNKRLTA PPAAFLCHLD NLLRPLLKDA AHPSEATFSC DCVADALILR VRSELSGLPF YWNFHCMLAS PSLVSQHLIR PLMGMSLALQ CQVRELATLL HMKDLEIQDY QESGATLIRD RLKTEPFEEN SFLEQFMIEK LPEACSIGDG KPFVMNLQDL YMAVTTQ
标签 :
多聚组氨酸标签
表达系统 :
大肠杆菌
产品类型名 :
重组蛋白
UniProt No. :
Q9H9Q4
内部搜索条款 :
NHEJ1, Non-homologous end-joining factor 1, XLF,ATGP1684-10ug,ATGP1684-20ug,ATGP1684-50ug,ATGP1684-100ug,ATGP1684-250ug,ATGP1684-500ug,ATGP1684-1mg,ATGP1684-10,ATGP1684-20,ATGP1684-50,ATGP1684-100,ATGP1684-250,ATGP1684-500,ATGP1684-1
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司，制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。