蛋白

重组人类金属蛋白酶组织抑制剂-2蛋白

ATGP1687

20微克

80美元

重组人类金属蛋白酶组织抑制剂-2蛋白

27-220aa

ATGP1687

NP_003246

TIMP2 is a natural inhibitor of the matrix metalloproteinases, a group of peptidases involved in of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, this protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, TIMP2 may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular. Recombinant human TIMP2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

TIMP metallopeptidase inhibitor 2, CSC-21K, CSC21K

0.5毫克/毫升(由布拉德福德Bradford检测确定)

液体。 20mM三羟甲基氨基甲烷氯化氢缓冲液(pH值8.0)含0.15M氯化钠, 10% 甘油, 1mM DTT

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Bahudhanapati,H., et al. (2011) J. Biol. Chem. 286 (36), 31761-31770;; Seo,D.W.,et al. (2011) Peptides 32 (9), 1840-1848

> 85% by SDS-PAGE

十二烷基磺酸钠-PAGE

人类

信号转导

26.1 kDa (232aa) confirmed by MALDI-TOF

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMCS CSPVHPQQAF CNADVVIRAK AVSEKEVDSG NDIYGNPIKR IQYEIKQIKM FKGPEKDIEF IYTAPSSAVC GVSLDVGGKK EYLIAGKAEG DGKMHITLCD FIVPWDTLST TQKKSLNHRY QMGCECKITR CPMIPCYISS PDECLWMDWV TEKNINGHQA KFFACIKRSD GSCAWYRGAA PPKQEFLDIE DP

多聚组氨酸标签

大肠杆菌

重组蛋白

P16035

TIMP2, TIMP metallopeptidase inhibitor 2, CSC-21K, CSC21K,ATGP1687-10ug,ATGP1687-20ug,ATGP1687-50ug,ATGP1687-100ug,ATGP1687-250ug,ATGP1687-500ug,ATGP1687-1mg,ATGP1687-10,ATGP1687-20,ATGP1687-50,ATGP1687-100,ATGP1687-250,ATGP1687-500,ATGP1687-1