产品简要
产品信息
产品类型 :
蛋白质
产品名 :
重组人类TDG蛋白
区域 :
1-410aa
目录号(SKU号) :
ATGP1705
NCBI :
AAH37557
描述 :
Thymine-DNA glycosylase, also known as TDG, belongs to the TDG/mug DNA glycosylase family. TDG is a nuclear protein which corrects G/T mismatches to G/C pairs by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired thymin. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. Recombinant human TDG protein, fused to His-tag at N-terminus, was expressed in E. coli
别称 :
Thymine-DNA glycosylase, G/T mismatch-specific thymine DNA glycosylase,
浓度 :
0.5毫克/毫升(由布拉德福德Bradford检测确定)
配方 :
液体。 20mM三羟甲基氨基甲烷氯化氢缓冲液(pH值8.0)含0.4尿素, 10% 甘油, 0.1M氯化钠
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
um S., et al. (1998) J Biol Chem. 273:20728-20736.;; Hardeland u., et al. (2002) EMBO J. 21:1456-1464.
纯度 :
> 85% by SDS-PAGE
应用 :
十二烷基磺酸钠-PAGE, 变性的
抗原物种 :
人类
基因类别 :
Epigenomics (Transcription & Translation)
分子量 :
48.4 kDa (433aa)
Bioassay Procedure :
MEAENAG SYSLQQAQAF YTFPFQQLMA EAPNMAVVNE QQMPEEVPAP APAQEPVQEA PKGRKRKPRT TEPKQPVEPK KPVESKKSGK SAKSKEKQEK ITDTFKVKRK VDRFNGVSEA ELLTKTLPDI LTFNLDIVII GINPGLMAAY KGHHYPGPGN HFWKCLFMSG LSEVQLNHMD DHTLPGKYGI GFTNMVERTT PGSKDLSSKE FREGGRILVQ KLQKYQPRIA VFNGKCIYEI FSKEVFGVKV KNLEFGLQPH KIPDTETLCY GMPSSSARCA QFPRAQDKVH YYIKLKDLRD QLKGIERNMD VQEVQYTFDL QLAQEDAKKM AVKEEKYDPG YEAAYGGAYG ENPCSSEPCG FSSNGLIESV ELRGESAFSG IPNGQWMTQS FTDQIPSFSN HCGTQEQEEE SHA
标签 :
多聚组氨酸标签
表达系统 :
大肠杆菌
产品类型名 :
重组蛋白
UniProt No. :
Q13569
内部搜索条款 :
TDG, ATGP1705-10微克, ATGP1705-20微克, ATGP1705-50微克, ATGP1705-100微克, ATGP1705-250微克, ATGP1705-500微克, ATGP1705-1毫克, ATGP1705-10, ATGP1705-20, ATGP1705-50, ATGP1705-100, ATGP1705-250, ATGP1705-500, ATGP1705-1
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司，制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。