产品简要
产品信息
产品类型 :
蛋白质
产品名 :
重组人类DEDD蛋白
区域 :
1-318aa
目录号(SKU号) :
ATGP1945
NCBI :
NP_127491
描述 :
Death effector domain-containing protein, also known as DEDD, is a cytoplasmic protein. It translocates to the nucleus during CD95-mediated apoptosis, where it localizes to nucleoli-like structures, activates caspase-6 and specifically inhibits RNA polymerase I-dependent transcription. The cell death activity of DEDD relates to its nuclear localization. DEDD is widely expressed in a variety of tissues, with highest levels in the testis. Overexpression of this gene was shown to induce weak apoptosis. Recombinant human DEDD protein, fused to His-tag at N-terminus, was expressed in E. coli.
别称 :
Death effector domain-containing protein, CASP8IP1, DEDD1, DEFT, FLDED1, KE05
浓度 :
0.5毫克/毫升(由布拉德福德Bradford检测确定)
配方 :
液体。 20mM三羟甲基氨基甲烷氯化氢缓冲液(pH值8.0)含0.4M尿素, 10% 甘油
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Stegh A H., et al. (1998) EMBO J. 17:5974-5986.;; Schickling O., et al. (2001) Cell Death Differ. 8:1157-1168.
纯度 :
> 85% by SDS-PAGE
应用 :
十二烷基磺酸钠-PAGE, 变性的
抗原物种 :
人类
基因类别 :
凋亡
分子量 :
38.9 kDa (338aa)
Bioassay Procedure :
MAGLKRRASQ VWPEEHGEQE HGLYSLHRMF DIVGTHLTHR DVRVLSFLFV DVIDDHERGL IRNGRDFLLA LERQGRCDES NFRQVLQLLR IITRHDLLPY VTLKRRRAVC PDLVDKYLEE TSIRYVTPRA LSDPEPRPPQ PSKTVPPHYP VVCCPTSGPQ MCSKRPARGR ATLGSQRKRR KSVTPDPKEK QTCDIRLRVR AEYCQHETAL QGNVFSNKQD PLERQFERFN QANTILKSRD LGSIICDIKF SELTYLDAFW RDYINGSLLE ALKGVFITDS LKQAVGHEAI KLLVNVDEED YELGRQKLLR NLMLQALP
标签 :
多聚组氨酸标签
表达系统 :
大肠杆菌
产品类型名 :
重组蛋白
UniProt No. :
O75618
内部搜索条款 :
DEDD, Death effector domain-containing protein, CASP8IP1, DEDD1, DEFT, FLDED1, KE05,ATGP1945-10ug,ATGP1945-20ug,ATGP1945-50ug,ATGP1945-100ug,ATGP1945-250ug,ATGP1945-500ug,ATGP1945-1mg,ATGP1945-10,ATGP1945-20,ATGP1945-50,ATGP1945-100,ATGP1945-250,ATGP1945-500,ATGP1945-1
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司，制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。