蛋白

重组人类胱氨酸-天冬氨酸蛋白酶3蛋白

ATGP2651

10微克

110美元

重组人类胱氨酸-天冬氨酸蛋白酶3蛋白

176-277aa

ATGP2651

NP_116786

CASP3 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Recombinant human CASP3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

胱氨酸-天冬氨酸蛋白酶3, CPP32, CPP32B, SCA-1

0.5毫克/毫升(由布拉德福德Bradford检测确定)

液体。 20mM三羟甲基氨基甲烷氯化氢缓冲液(pH值8.0)含0.4M尿素, 10% 甘油

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Harrington HA, Ho KL, et al. (2008). Theor Biol Med Model. 10;;5:26.

> 80% by SDS-PAGE

十二烷基磺酸钠-PAGE

人类

凋亡

12 kDa (103aa)

MSGVDDDMAC HKIPVEADFL YAYSTAPGYY SWRNSKDGSW FIQSLCAMLK QYADKLEFMH ILTRVNRKVA TEFESFSFDA TFHAKKQIPC IVSMLTKELY FYH

Non-Tagged

大肠杆菌

重组蛋白

P42574

Caspase3, 胱氨酸-天冬氨酸蛋白酶3, CPP32, CPP32B, SCA-1, ATGP2651-10微克, ATGP2651-20微克, ATGP2651-50微克, ATGP2651-100微克, ATGP2651-250微克, ATGP2651-500微克, ATGP2651-1毫克, ATGP2651-10, ATGP2651-20, ATGP2651-50, ATGP2651-100, ATGP2651-250, ATGP2651-500, ATGP2651-1