蛋白

Recombinant human Langerin/CD207 protein

ATGP3330

10微克

80美元

Recombinant human Langerin/CD207 protein

65-328aa

ATGP3330

NP_056532

CD207, also known as C-type lectin domain family 4 member K, is a type 2 transmembrane glycoprotein. This protein is used as a marker for Langerhans cell which represent the immature dendritic cells in the epidermis. Also, it internalizes endogenous proteins such as type 1 procollagen. Internalization by Langerhans cell is thought to lead to suppression of self reactions. CD207 meditates endocytosis of non-peptide antigens containing mannose, N-acetyl glucosamine and fucose that are expressed by mycobacteria and fungae. Recombinant human CD207, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

C-type lectin domain family 4 member K, Langerin, CLEC4K

1mg/ml (determined by absorbance at 280nm)

液体。 磷酸盐缓冲液(pH值7.4)含10% 甘油

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Ward EM., et al. (2006) J. Biol. Chem. 281:15450-15456.;; Chabrol E., et al. (2012) PLoS ONE. 7:E50722.

> 90% by SDS-PAGE

十二烷基磺酸钠-PAGE

人类

信号转导

30.9 kDa (273aa)

< 1 EU per 1ug of protein (determined by LAL method)

PRFMGTI SDVKTNVQLL KGRVDNISTL DSEIKKNSDG MEAAGVQIQM VNESLGYVRS QFLKLKTSVE KANAQIQILT RSWEEVSTLN AQIPELKSDL EKASALNTKI RALQGSLENM SKLLKRQNDI LQVVSQGWKY FKGNFYYFSL IPKTWYSAEQ FCVSRNSHLT SVTSESEQEF LYKTAGGLIY WIGLTKAGME GDWSWVDDTP FNKVQSARFW IPGEPNNAGN NEHCGNIKAP SLQAWNDAPC DKTFLFICKR PYVPSEP

多聚组氨酸标签

杆状病毒

Ala

重组蛋白

Q9UJ71

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