产品简要
产品信息
产品类型 :
蛋白质
产品名 :
重组人类IL-23蛋白
区域 :
23-328aa(p40)/20-189aa(p19)
目录号(SKU号) :
ATGP3598
NCBI :
NP_002178(p40)NP_057668(p19)
描述 :
IL23 p40 and p19, also known as interleukin-12 subunit beta/interleukin-23 subunit alpha, is a heterodimeric cytokine composed of two disulfide-linked subunit, a p19 subunit that is unique to IL23, and a p40 subunit that is shared with IL12. The p19 subunit has homology to the p35 subunit of IL12, as well as to other single chain sytokines sub as IL6 and IL11. It is produced by macrophages and B lymphocytes and has multiple effects on T-cells and NK cells, including stimulation of cytotoxic activity, proliferation, and promotion of Th1 development as well as IFN-gamma and TNF production. Recombinant human IL23 p40 and p19, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
别称 :
白细胞介素12亚单位乙/白细胞介素23亚单位甲, CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2/IL-23, IL-23A, IL23P19, P19, SGRF
浓度 :
1mg/ml (determined by absorbance at 280nm)
配方 :
液体。 磷酸盐缓冲液(pH值7.4)含10% 甘油
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Oppmann B., et al, (2000) Immunity. 13:715-25.;; Parham C., et al, (2002) J. lmmunol. 168:5699-708.
纯度 :
> 95% by SDS-PAGE
应用 :
十二烷基磺酸钠-PAGE
抗原物种 :
人类
基因类别 :
激素&细胞因子
分子量 :
34.6 kDa (p40, 306aa);;19.5 kDa (p19, 176aa)
内毒素 :
< 1 EU per 1ug of protein (determined by LAL method)
Bioassay Procedure :
IL12B(p40);;IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKNKTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCGA ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVHKLKYEN YTSSFFIRDI IKPDPPKNLQ LKPLKNSRQV EVSWEYPDTW STPHSYFSLT FCVQVQGKSK REKKDRVFTD KTSATVICRK NASISVRAQD RYYSSSWSEW ASVPCS;;IL23A(p19);;RAVPGGSSPA WTQCQQLSQK LCTLAWSAHP LVGHMDLREE GDEETTNDVP HIQCGDGCDP QGLRDNSQFC LQRIHQGLIF YEKLLGSDIF TGEPSLLPDS PVGQLHASLL GLSQLLQPEG HHWETQQIPS LSPSQPWQRL LLRFKILRSL QAFVAVAARV FAHGAATLSP
标签 :
多聚组氨酸标签
表达系统 :
杆状病毒
Predicted nterm :
Ile23, Arg20
产品类型名 :
重组蛋白
UniProt No. :
P29460(p40)/Q9NPF7(p19)
内部搜索条款 :
IL23, ATGP3598-10微克, ATGP3598-20微克, ATGP3598-50微克, ATGP3598-100微克, ATGP3598-250微克, ATGP3598-500微克, ATGP3598-1毫克, ATGP3598-10, ATGP3598-20, ATGP3598-50, ATGP3598-100, ATGP3598-250, ATGP3598-500, ATGP3598-1
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司，制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。