蛋白

重组人类CD28蛋白

ATGP3603

10微克

80美元

重组人类CD28蛋白

19-152aa

ATGP3603

NP_006130.1

CD28, also known as T-cell-specific surface glycoprotein CD28 isoform 1, is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins (IL-6 in particular). CD28/B7 interaction has been shown to prevent apoptosis of activated T cells via the up-regulation of bcl-XL. It ligation has also been shown to regulate Th1/Th2 differentiation. Recombinant human CD28, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

T-cell-specific surface glycoprotein CD28 isoform 1, CD28, Tp44

1mg/ml (determined by absorbance at 280nm)

液体。 磷酸盐缓冲液(pH值7.4)含10% 甘油

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Prasad KV., et al. (1994) National Academy. 91: 2834 -2838.;; Okkenhaug K., et al. (1998) J. Biol. Chem. 273: 21194 -21202.

> 90% by SDS-PAGE

Measured by its binding ability in a functional ELISA with Human CD80 (CAT# ATGP3663). The ED50 range ≤ 60ug/ml.

SDS-PAGE, Bioactivity

人类

免疫学

42.4 kDa (376aa)

< 1 EU per 1ug of protein (determined by LAL method)

Human CD80 (CAT# ATGP3663) is coated at 1 ug/ml (100 ul/well) can bind Human CD28. The ED50 range ≤ 60ug/ml.

NKILVKQ SPMLVAYDNA VNLSCKYSYN LFSREFRASL HKGLDSAVEV CVVYGNYSQQ LQVYSKTGFN CDGKLGNESV TFYLQNLYVN QTDIYFCKIE VMYPPPYLDN EKSNGTIIHV KGKHLCPSPL FPGPSKP

hIgG-His-Tag

杆状病毒

Ala

重组蛋白

P10747

CD28, ATGP3603-10微克, ATGP3603-20微克, ATGP3603-50微克, ATGP3603-100微克, ATGP3603-250微克, ATGP3603-500微克, ATGP3603-1毫克, ATGP3603-10, ATGP3603-20, ATGP3603-50, ATGP3603-100, ATGP3603-250, ATGP3603-500, ATGP3603-1