产品简要
产品信息
产品类型 :
蛋白质
产品名 :
重组人类PDGF R乙蛋白
区域 :
33-532aa
目录号(SKU号) :
ATGP3721
NCBI :
NP_002600
描述 :
PDGFRB, also known as platelet-derived growth factor receptor beta, is a member of the class III subfamily of receptor tyrosine kinases (RTK) that also includes the receptors for M-CSF, SCF and Flt3-ligand. It plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. It promotes rearrangement of the actin cytoskeleton and the formation of membrane ruffles. It phosphorylates PLCG1, PIK3R1, PTPN11, RASA1/GAP, CBL, SHC1 and NCK1. Recombinant human PDGFRB, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
别称 :
血小板衍生生长因子受体乙, 血小板衍生的生长因子受体b, CD140B, IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, 血小板衍生的生长因子受体1, PENTT
浓度 :
0.25毫克/毫升(由布拉德福德Bradford检测确定)
配方 :
液体。 磷酸盐缓冲液(pH值7.4)含10% 甘油
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Kelly JD., et al. (1991) J Biol Chem. 266:8987-8992.;; Kashishian A., et al. (1992) EMBO J. 11:1373-1382.
纯度 :
> 90% by SDS-PAGE
应用 :
十二烷基磺酸钠-PAGE
抗原物种 :
人类
基因类别 :
Cardiovascular
分子量 :
83.3 kDa (739aa)
内毒素 :
< 1 EU per 1ug of protein (determined by LAL method)
Bioassay Procedure :
LVVTPPGPEL VLNVSSTFVL TCSGSAPVVW ERMSQEPPQE MAKAQDGTFS SVLTLTNLTG LDTGEYFCTH NDSRGLETDE RKRLYIFVPD PTVGFLPNDA EELFIFLTEI TEITIPCRVT DPQLVVTLHE KKGDVALPVP YDHQRGFSGI FEDRSYICKT TIGDREVDSD AYYVYRLQVS SINVSVNAVQ TVVRQGENIT LMCIVIGNEV VNFEWTYPRK ESGRLVEPVT DFLLDMPYHI RSILHIPSAE LEDSGTYTCN VTESVNDHQD EKAINITVVE SGYVRLLGEV GTLQFAELHR SRTLQVVFEA YPPPTVLWFK DNRTLGDSSA GEIALSTRNV SETRYVSELT LVRVKVAEAG HYTMRAFHED AEVQLSFQLQ INVPVRVLEL SESHPDSGEQ TVRCRGRGMP QPNIIWSACR DLKRCPRELP PTLLGNSSEE ESQLETNVTY WEEEQEFEVV STLRLQHVDR PLSVRCTLRN AVGQDTQEVI VVPHSLPFKV
标签 :
hIgG-His-Tag
表达系统 :
杆状病毒
Predicted nterm :
Leu33
产品类型名 :
重组蛋白
UniProt No. :
P09619
内部搜索条款 :
PDGF R b, 血小板衍生生长因子受体乙, 血小板衍生的生长因子受体b, CD140B, IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, 血小板衍生的生长因子受体1, PENTT, ATGP3721-10微克, ATGP3721-20微克, ATGP3721-50微克, ATGP3721-100微克, ATGP3721-250微克, ATGP3721-500微克, ATGP3721-1毫克, ATGP3721-10, ATGP3721-20, ATGP3721-50, ATGP3721-100, ATGP3721-250, ATGP3721-500, ATGP3721-1
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司，制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。