蛋白

重组人类CD147/BSG蛋白

ATGP3737

10微克

80美元

重组人类CD147/BSG蛋白

22-207aa

ATGP3737

NP_940991

BSG, also known as basigin isoform 2, is a type 1 transmembrane protein with various different N- and O- glycosylation that belongs to the immunoglobulin superfamily. As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development, it is thought also to play a role in intercellular recognition. This protein has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins and regulates several distinct functions, such as spermatogenesis, expression of the mono-carboxylate transporter and the responsiveness of lymphocytes. Also, it induces the production and release of matrix metalloproteinases in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Recombinant human BSG, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Basigin isoform 2, OK, Ok blood group, Extracellular matrix metalloproteinase inducer, Tumor cell-derived collagenase stimulatory factor, TCSF, Collagenase stimulatory factor, Hepatoma-associated antigen, HAb18G, Leukocyte activation antigen M6, EMMPRIN, CD147, EMPRIN, 5F7

0.5mg/ml (determined by absorbance at 280nm)

液体。 磷酸盐缓冲液(pH值7.4)含10% 甘油

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Gabison EE., et al, (2005) Biochimie 87:361-368.;; Hanna SM., et al, (2003) BMC Biochem 4:17-25.

> 90% by SDS-PAGE

十二烷基磺酸钠-PAGE

人类

免疫学

47.5 kDa (428aa)

< 1 EU per 1ug of protein (determined by LAL method)

ADPAAGTVFT TVEDLGSKIL LTCSLNDSAT EVTGHRWLKG GVVLKEDALP GQKTEFKVDS DDQWGEYSCV FLPEPMGTAN IQLHGPPRVK AVKSSEHINE GETAMLVCKS ESVPPVTDWA WYKITDSEDK ALMNGSESRF FVSSSQGRSE LHIENLNMEA DPGQYRCNGT SSKGSDQAII TLRVRSHLAL EPKSCDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GKHHHHHH

hIgG-His-Tag

杆状病毒

Ala

重组蛋白

P35613

BSG, Basigin isoform 2, BSG, 5F7, CD147, EMMPRIN, OK, TCSF,ATGP3737-10ug,ATGP3737-20ug,ATGP3737-50ug,ATGP3737-100ug,ATGP3737-250ug,ATGP3737-500ug,ATGP3737-1mg,ATGP3737-10,ATGP3737-20,ATGP3737-50,ATGP3737-100,ATGP3737-250,ATGP3737-500,ATGP3737-1