蛋白

重组人类S6K1/核糖体蛋白S6激酶蛋白

ATGP3741

10微克

240美元

重组人类S6K1/核糖体蛋白S6激酶蛋白

1-525aa, 人类

ATGP3741

NP_003152

RPS6KB1, also known as ribosomal protein S6 kinase beta-1 isoform a, is a serine/threonine kinase that acts downstream of PIP3 and phosphoinositide-dependent kinase-1 in the PI3 kinase pathway. Phosphorylation of S6 induces protein synthesis at the ribosome. The phosphorylation of p70S6K at threonine 389 has been used as a hallmark of activation by mTOR and correlated with autophagy inhibition in various situations. However, several recent studies suggest that the activity of p70S6K plays a more positive role in the increase of autophagy. Recombinant human RPS6KB1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

STK14A, Serine/threonine-protein kinase 14A, S6K-beta-1, S6K1, S6K, RPS6KB1, Ribosomal protein S6 kinase I, Ribosomal protein S6 kinase beta-1 isoform a, PS6K, P70S6K1, p70-S6K, p70-alpha, p70(S6K)-alpha, p70 S6KA, p70 S6 kinase alpha, p70 ribosomal S6 kinase alpha, 70 kDa ribosomal protein S6 kinase 1

0.25毫克/毫升(由布拉德福德Bradford检测确定)

液体。 50mM三羟甲基氨基甲烷氯化氢缓冲液(pH值8.0)含40% 甘油, 0.5M氯化钠, 2mM DTT, 0.1mM苯甲基磺酰氟

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Grove JR., et al, (1991) Mol Cell Biol. 11:5541-5550.;; Ferrari S., et al, (1994) Crit Rev Biochem Mol Biol. 29:385-413.

> 85% by SDS-PAGE

十二烷基磺酸钠-PAGE

人类

Epigenomics (Transcription & Translation)

60.2 kDa (533aa)

< 1 EU per 1ug of protein (determined by LAL method)

MRRRRRRDGF YPAPDFRDRE AEDMAGVFDI DLDQPEDAGS EDELEEGGQL NESMDHGGVG PYELGMEHCE KFEISETSVN RGPEKIRPEC FELLRVLGKG GYGKVFQVRK VTGANTGKIF AMKVLKKAMI VRNAKDTAHT KAERNILEEV KHPFIVDLIY AFQTGGKLYL ILEYLSGGEL FMQLEREGIF MEDTACFYLA EISMALGHLH QKGIIYRDLK PENIMLNHQG HVKLTDFGLC KESIHDGTVT HTFCGTIEYM APEILMRSGH NRAVDWWSLG ALMYDMLTGA PPFTGENRKK TIDKILKCKL NLPPYLTQEA RDLLKKLLKR NAASRLGAGP GDAGEVQAHP FFRHINWEEL LARKVEPPFK PLLQSEEDVS QFDSKFTRQT PVDSPDDSTL SESANQVFLG FTYVAPSVLE SVKEKFSFEP KIRSPRRFIG SPRTPVSPVK FSPGDFWGRG ASASTANPQT PVEYPMETSG IEQMDVTMSG EASAPLPIRQ PNSGPYKKQA FPMISKRPEH LRMNL

多聚组氨酸标签

杆状病毒

Met1

重组蛋白

P23443

RPS6KB1, Ribosomal protein S6 kinase beta-1 isoform a, RPS6KB1, p70 S6KA, p70(S6K)-alpha, p70-alpha, p70-S6K, PS6K, S6K, S6K-beta-1, S6K1, STK14A,ATGP3741-10ug,ATGP3741-20ug,ATGP3741-50ug,ATGP3741-100ug,ATGP3741-250ug,ATGP3741-500ug,ATGP3741-1mg,ATGP3741-10,ATGP3741-20,ATGP3741-50,ATGP3741-100,ATGP3741-250,ATGP3741-500,ATGP3741-1