产品简要
产品信息
产品类型 :
蛋白质
产品名 :
重组人类HLA-G蛋白
区域 :
25-308aa
目录号(SKU号) :
ATGP3743
NCBI :
NP_002118.1
描述 :
HLA-G, also known as HLA class I histocompatibility antigen, alpha chain G, belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. HLA-G is a non-classical class-I HLA molecule associated with anti-inflammatory and immuno-modulatory properties which interacts with inhibitory receptors (ILT2/ILT4/KIR2DL4) present on various immune cells. It inhibits proliferation of B cells, T cells and natural killer cells; and also induces regulatory T cells. Recombinant human HLA-G, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
别称 :
HLAⅠ类组织相容性抗原, 甲链G, MHC-G
浓度 :
0.25mg/ml (determined by absorbance at 280nm)
配方 :
液体。 磷酸盐缓冲液(pH值7.4)含20% 甘油
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Poomarimuthu M., et al. (2017) Pediatr Rheumatol Online J. 15(1):10.;; Sanders SK., et al. (1991) J Exp Med. 174(3):737-40.
纯度 :
> 90% by SDS-PAGE
应用 :
十二烷基磺酸钠-PAGE
抗原物种 :
人类
基因类别 :
免疫学
分子量 :
35.3 kDa (309aa) confirmed by MALDI-TOF
Bioassay Procedure :
GSHSM RYFSAAVSRP GRGEPRFIAM GYVDDTQFVR FDSDSACPRM EPRAPWVEQE GPEYWEEETR NTKAHAQTDR MNLQTLRGYY NQSEASSHTL QWMIGCDLGS DGRLLRGYEQ YAYDGKDYLA LNEDLRSWTA ADTAAQISKR KCEAANVAEQ RRAYLEGTCV EWLHRYLENG KEMLQRADPP KTHVTHHPVF DYEATLRCWA LGFYPAEIIL TWQRDGEDQT QDVELVETRP AGDGTFQKWA AVVVPSGEEQ RYTCHVQHEG LPEPLMLRWK QSSLPTIPI
标签 :
多聚组氨酸标签
表达系统 :
大肠杆菌
产品类型名 :
重组蛋白
UniProt No. :
P17693
内部搜索条款 :
HLA-G, ATGP3743-10微克, ATGP3743-20微克, ATGP3743-50微克, ATGP3743-100微克, ATGP3743-250微克, ATGP3743-500微克, ATGP3743-1毫克, ATGP3743-10, ATGP3743-20, ATGP3743-50, ATGP3743-100, ATGP3743-250, ATGP3743-500, ATGP3743-1
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司，制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。