产品简要
公司名称 :
NKMAX
产品类型 :
蛋白
产品名称 :
重组人类胱氨酸-天冬氨酸蛋白酶3蛋白
目录 :
ATGP3874
规格 :
10微克
价格 :
235美元
更多信息或购买 :
产品信息
产品类型 :
蛋白质
产品名 :
重组人类胱氨酸-天冬氨酸蛋白酶3蛋白
区域 :
29-277aa
目录号(SKU号) :
ATGP3874
NCBI :
NP_116786
描述 :
Caspase-3, also known as caspase-3 isoform a, is a member of the cysteine-aspartic acid protease (caspase) family of enzymes. This protein is most abundant in cell lines of lymphocytic origin. Also, it activates caspases 6 and 7 and the protein itself is processed and is activated by caspases 8, 9, and 10. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits that dimerize to form the active enzyme. Members of the caspase family of proteases play central roles in coordinating the stereotypical events that occur during apoptosis. Recombinant Human Caspase-3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
别称 :
CASP3, CPP32, CPP32B, SCA-1, CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1
浓度 :
0.5mg/ml (determined by absorbance at 280nm)
配方 :
液体。 20mM羟乙基哌嗪乙磺酸缓冲液(pH值7.4)含0.1M氯化钠, 1mM乙二胺四乙酸, 1mM DTT, 20% 甘油
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Walsh JG., et al, (2008) Proc. Natl. Scad. Sci. USA 105:12815.;;Fernandes-Alnemri T., et al, (1994) J. Biol. Chem. 269:30761-30764.
纯度 :
> 90% by SDS-PAGE
Bioactivity Comment Only :
Specific activity is > 5,000pmol/min/ug. One unit will liberate 1pmole of Ac-DEVD-AFC to Ac-DEVD and AFC per minute at pH7.5 at 25C.
应用 :
十二烷基磺酸钠-PAGE, 酶活性
抗原物种 :
人类
基因类别 :
神经科学
分子量 :
29.4 kDa (256aa)ns)
内毒素 :
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics :
Specific activity is > 5,000 pmol/min/ug. One unit will liberate 1 pmole of Ac-DEVD-AFC to Ac-DEVD and AFC per minute at pH7.5 at 25C.
Bioassay Procedure :
MSGISLDNSY KMDYPEMGLC IIINNKNFHK STGMTSRSGT DVDAANLRET FRNLKYEVRN KNDLTREEIV ELMRDVSKED HSKRSSFVCV LLSHGEEGII FGTNGPVDLK KITNFFRGDR CRSLTGKPKL FIIQACRGTE LDCGIETDSG VDDDMACHKI PVEADFLYAY STAPGYYSWR NSKDGSWFIQ SLCAMLKQYA DKLEFMHILT RVNRKVATEF ESFSFDATFH AKKQIPCIVS MLTKELYFYH
标签 :
多聚组氨酸标签
表达系统 :
杆状病毒
Predicted nterm :
Ser29
产品类型名 :
重组蛋白
UniProt No. :
P42574
内部搜索条款 :
Caspase3, ATGP3874-10微克, ATGP3874-20微克, ATGP3874-50微克, ATGP3874-100微克, ATGP3874-250微克, ATGP3874-500微克, ATGP3874-1毫克, ATGP3874-10, ATGP3874-20, ATGP3874-50, ATGP3874-100, ATGP3874-250, ATGP3874-500, ATGP3874-1
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司，制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。