产品简要
公司名称 :
NKMAX
产品类型 :
蛋白
产品名称 :
重组人类HMG-1/hmgb1蛋白
目录 :
HMG0801
规格 :
20微克
价格 :
105美元
更多信息或购买 :
文章摘录数: 3
参考文献 |
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产品信息
产品类型 :
蛋白质
产品名 :
重组人类HMG-1/hmgb1蛋白
区域 :
1-215aa
目录号(SKU号) :
HMG0801
NCBI :
NP_002119.1
描述 :
High mobility group box1 protein (HMGB1) is a very abundant chromatin-binding protein residing in the eukaryotic cell nucleus and acting in the assembly of nucleoprotein complexes. Inside the cell, HMGB1 binds to DNA and has a role in transcriptional regulation. Outside the cell, HMGB1 acts as a cytokine and has activities that resemble those of tumor necrosis factor. Recombinant human HMGB1 was expressed in insect cells and purified by conventional chromatography techniques.
别称 :
Sulfoglucuronyl carbohydrate binding protein, SBP-1, HMGB1, HMG3, HMG1, High-mobility group box1, High-mobility group (nonhistone chromosomal) protein 1, DKFZp686A04236, Amphoterin
浓度 :
1毫克/毫升(由布拉德福德Bradford检测确定)
配方 :
液体。 20mM三羟甲基氨基甲烷氯化氢缓冲液(pH值8.0)含1mM乙二胺四乙酸, 0.5mM DTT, 10% 甘油
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Palumbo R J., et al. (2004) Cell Biol. 164(3):441-9.;; Andersson u., et al (2002) Leukoc Biol. 72(6):1084-91.;;
纯度 :
> 90% by SDS-PAGE
应用 :
十二烷基磺酸钠-PAGE
抗原物种 :
人类
基因类别 :
Epigenomics (Transcription & Translation)
分子量 :
25 kDa (223aa) confirmed by MALDI-TOF
内毒素 :
< 1 EU per 1ug of protein (determined by LAL method)
Bioassay Procedure :
MGKGDPKKPR GKMSSYAFFV QTCREEHKKK HPDASVNFSE FSKKCSERWK TMSAKEKGKF EDMAKADKAR YEREMKTYIP PKGETKKKFK DPNAPKRPPS AFFLFCSEYR PKIKGEHPGL SIGDVAKKLG EMWNNTAADD KQPYEKKAAK LKEKYEKDIA AYRAKGKPDA AKKGVVKAEK SKKKKEEEED EEDEEDEEEE EDEEDEDEEE DDDDE
标签 :
多聚组氨酸标签
表达系统 :
杆状病毒
产品类型名 :
重组蛋白
UniProt No. :
P09429
内部搜索条款 :
Sulfoglucuronyl carbohydrate binding protein, SBP-1, SBP1, SBP 1, HMGB1, HMGB 1, HMG3, HMG1, HMG 1, High-mobility group box1, High-mobility group (nonhistone chromosomal) protein 1, DKFZp686A04236, Amphoterin, HMG 3, High mobility group box1, High mobility group (nonhistone chromosomal) protein 1, High mobility group protein 1, HMG0801-10ug, HMG0801-20ug, HMG0801-50ug, HMG0801-100ug, HMG0801-250ug, HMG0801-500ug, HMG0801-1mg, HMG0801-010, HMG0801-020, HMG0801-050, HMG0801-100, HMG0801-250, HMG0801-500, HMG0801-01M
References with this Product :
Min HJ, et al. Chaperone-like Activity of High-Mobility Group Box 1 Protein and Its Role in Reducing the Formation of Polyglutamine Aggregates. (J Immunol. 2013){https://www.ncbi.nlm.nih.gov/pubmed/23303669};;Slean MM, et al. Interconverting Conformations of Slipped-DNA Junctions Formed by Trinucleotide Repeats Affect Repair Outcome. (Biochemistry. 2013){https://www.ncbi.nlm.nih.gov/pubmed/23339280};;Takahashi T, et al. Bone-Targeting Endogenous Secretory Receptor for Advanced Glycation End Products Rescues Rheumatoid Arthritis. (Mol Med. 2013){https://www.ncbi.nlm.nih.gov/pubmed/23821362};;Roy A, et al. Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation. (J Biol Chem. 2014){https://pubmed.ncbi.nlm.nih.gov/24257755/};;Sugimoto K, et al. Receptor for Advanced Glycation End Products - Membrane Type1 Matrix Metalloproteinase Axis Regulates Tissue Factor Expression via RhoA and Rac1 Activation in High-Mobility Group Box-1 Stimulated Endothelial Cells. (PLoS One. 2014){https://pubmed.ncbi.nlm.nih.gov/25490770/};;Hernández-Pando R, et al. The Role of High Mobility Group Box 1 Protein (HMGB1) in the Immunopathology of Experimental Pulmonary Tuberculosis. (PLoS One. 2015){https://pubmed.ncbi.nlm.nih.gov/26201072/};;Ito M, et al. High mobility group box 1 enhances hyperthermia-induced seizures and secondary epilepsy associated with prolonged hyperthermia-induced seizures in developing rats. (Metab Brain Dis. 2017){https://pubmed.ncbi.nlm.nih.gov/28879430/}
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司,制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。