产品简要
公司名称 :
NKMAX
产品类型 :
蛋白
产品名称 :
重组人类HSP27蛋白
目录 :
HSP0503
规格 :
20微克
价格 :
55美元
更多信息或购买 :
文章摘录数: 1
参考文献
Kaiser F, Steptoe A, Thompson S, Henderson B. Monocyte cytokine synthesis in response to extracellular cell stress proteins suggests these proteins exhibit network behaviour. Cell Stress Chaperones. 2014;19:135-44 pubmed 出版商
产品信息
产品类型 :
蛋白质
产品名 :
重组人类HSP27蛋白
区域 :
1-205aa
目录号(SKU号) :
HSP0503
NCBI :
NP_001531
描述 :
Hsp27 (also known as the Estrogen-Regulated 24K protein, and hsp 28) is a member of the mammalian small heat shock protein family. Hsp27 is expressed constitutively in many tissues and its expression is increased to high levels after various types of stress including elevated temperatures, toxic metals, drugs and oxidants. Also, Hsp27 is phosphorylated in vivo on three phosphorylation sites (Ser15, Ser78 and Ser82) by protein kinases including MAPKAP kinase 2 and the stress-activated protein kinase SAPK2 (p38). Recombinant human Hsp27 was overexpressed in E. coli and purified by conventional chromatography.
别称 :
Heat shock 27 kDa protein, Hspb1, Hsp25, Hsp27, Hsp27, HspB1, Heat shock 27 kDa protein, HSP 27, Growth-related 25 kDa protein, P25, HSP25, Heat shock protein beta-1, Heat shock 27 kDa protein 28 kDa heat shock protein, CMT2F, DKFZp586P1322, Estrogen regulated 24 kDa protein, at shock 25kDa protein 1, Heat shock 27kDa protein 1, Heat shock 28kDa protein 1, Heat Shock Protein 27, Heat shock protein beta 1, Heat Shock Protein27, HS.76067, Hsp 28, Hsp B1, Hsp28, HspB1, SRP27, Stress responsive protein 27.
浓度 :
1毫克/毫升(由布拉德福德Bradford检测确定)
配方 :
液体。 20mM羟乙基哌嗪乙磺酸缓冲液(pH值7.4)含100mM氯化钾, 1mM DTT
储存 :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
一般参考 :
Ehrnsperger M.,et al. (1997) EMBO J. 16, 221-229;; Butt E., et al. (2001) J. Biol. Chem. 276, 7108-7113;;
纯度 :
> 95% by SDS-PAGE
应用 :
十二烷基磺酸钠-PAGE
抗原物种 :
人类
基因类别 :
热休克蛋白
分子量 :
22.7 kDa (205aa) confirmed by MALDI-TOF
内毒素 :
< 1 EU per 1ug of protein (determined by LAL method)
Bioassay Procedure :
MTERRVPFSL LRGPSWDPFR DWYPHSRLFD QAFGLPRLPE EWSQWLGGSS WPGYVRPLPP AAIESPAVAA PAYSRALSRQ LSSGVSEIRH TADRWRVSLD VNHFAPDELT VKTKDGVVEI TGKHEERQDE HGYISRCFTR KYTLPPGVDP TQVSSSLSPE GTLTVEAPMP KLATQSNEIT IPVTFESRAQ LGGPEAAKSD ETAAK
标签 :
Non-Tagged
表达系统 :
大肠杆菌
产品类型名 :
重组蛋白
UniProt No. :
P04792
内部搜索条款 :
HSP27, Heat shock 27 kDa protein, Hspb1, Hsp25, Hsp27, Hsp27, HspB1, Heat shock 27 kDa protein, HSP 27, Growth-related 25 kDa protein, P25, HSP25, Heat shock protein beta-1, Heat shock 27 kDa protein 28 kDa heat shock protein, CMT2F, DKFZp586P1322, Estrogen regulated 24 kDa protein, at shock 25kDa protein 1, Heat shock 27kDa protein 1, Heat shock 28kDa protein 1, Heat Shock Protein 27, Heat shock protein beta 1, Heat Shock Protein27, HS.76067, Hsp 28, Hsp B1, Hsp28, HspB1, SRP27, Stress responsive protein 27.,HSP0503-10ug,HSP0503-20ug,HSP0503-50ug,HSP0503-100ug,HSP0503-250ug,HSP0503-500ug,HSP0503-1mg,HSP0503-10,HSP0503-20,HSP0503-50,HSP0503-100,HSP0503-250,HSP0503-500,HSP0503-1
References with this Product :
Kaiser F, et al. Monocyte cytokine synthesis in response to extracellular cell stress proteins suggests these proteins exhibit network behaviour. (Cell Stress Chaperones. 2014){https://pubmed.ncbi.nlm.nih.gov/23775284/};;Kaiser F, et al. Association between circulating levels of heat-shock protein 27 and aggressive periodontitis. (Cell Stress Chaperones. 2018){https://pubmed.ncbi.nlm.nih.gov/29766408/};;Grotegut P, et al. Destructive Effect of Intravitreal Heat Shock Protein 27 Application on Retinal Ganglion Cells and Neurofilament. (Int J Mol Sci. 2020){https://pubmed.ncbi.nlm.nih.gov/31952234/};;Eickholz P, et al. Effect of nonsurgical periodontal therapy on haematological parameters in grades B and C periodontitis: an exploratory analysis. (Clin Oral Investig. 2020){https://pubmed.ncbi.nlm.nih.gov/32385656/};;Grotegut P, et al. Heat Shock Protein 27 Injection Leads to Caspase Activation in the Visual Pathway and Retinal T-Cell Response. (Int J Mol Sci. 2021){https://pubmed.ncbi.nlm.nih.gov/33419223/};;Erb C, et al. HSP27 induced glaucomatous damage in mice of young and advanced age. (Front Cell Neurosci. 2023){https://pubmed.ncbi.nlm.nih.gov/37744880/}
更多信息或购买 :
公司信息
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
公司总部: 韩国
NKMAX有限公司是一家生物技术公司,制造和供应独特的优质蛋白质和抗体以供应世界各地的研究人员和零售商。