蛋白

重组人类IL-1乙/IL1B蛋白

ILB0701

10微克

44美元

重组人类IL-1乙/IL1B蛋白

117-269aa

ILB0701

NP_000567.1

Interleukin-1 (IL-1) has been considered a potentially important inflammatory mediator. It is composed of two distinct proteins, called as IL-1alpha and IL-1beta. IL-1beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta bind to the same receptor and they are structurally related polypeptides that share approximately 20% amino acid. Recombinant human IL-1beta was expressed in E. coli and purified by using conventional chromatography techniques.

Interleukin-1 beta, IL-1 beta, Catabolin, IL1F2

1mg/ml (determined by BCA assay)

液体。 磷酸盐缓冲液(pH值7.4)

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Allan SM., et al. (2005), Nat. Rev. Immunol. 5:629.;; Michaud DS., et al. (2006), Cancer Res.66(8):4525-30;;

> 95% by SDS-PAGE

Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 range ≤ 12pg/ml.

SDS-PAGE, Bioactivity

人类

激素&细胞因子

17 kDa (154aa) confirmed by MALDI-TOF

< 1 EU per 1ug of protein (determined by LAL method)

Human IL-1 beta /IL-1F2 stimulates cell proliferation of the D10.G4.1 mouse helper T cells. The ED50 range ≤ 12 pg/ml.

MAPVRSLNCT LRDSQQKSLV MSGPYELKAL HLQGQDMEQQ VVFSMSFVQG EESNDKIPVA LGLKEKNLYL SCVLKDDKPT LQLESVDPKN YPKKKMEKRF VFNKIEINNK LEFESAQFPN WYISTSQAEN MPVFLGGTKG GQDITDFTMQ FVSS

Non-Tagged

大肠杆菌

重组蛋白

P01584

IL1 b, IL1F2, ILB0701-10微克, ILB0701-20微克, ILB0701-50微克, ILB0701-100微克, ILB0701-250微克, ILB0701-500微克, ILB0701-1毫克, ILB0701-10, ILB0701-20, ILB0701-50, ILB0701-100, ILB0701-250, ILB0701-500, ILB0701-1

Choi DY, et al. Molecularly imprinted polymer-based electrochemical impedimetric sensors on screen-printed carbon electrodes for the detection of trace cytokine IL-1β. (Biosens Bioelectron. 2022){https://pubmed.ncbi.nlm.nih.gov/35144170/}