蛋白

重组人类MIF蛋白

MIF0801

20微克

105美元

重组人类MIF蛋白

1-115aa

MIF0801

NP_002406

The cytokine Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF has the unique property of being released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secretion of MIF is tightly regulated and decreases at high, anti-inflammatory steroid concentration. Recombinant human MIF was expressed in E. coli and purified by conventional chromatography techniques

Macrophage migration inhibitory factor, GLIF, MMIF, MIF, EC 5.3.2.1, Phenylpyruvate tautomerase, Glycosylation-inhibiting factor, GIF, Macrophage migration inhibitory factor, macrophage migration inhibitory factor (glycosylation-inhibiting factor),

1毫克/毫升(由布拉德福德Bradford检测确定)

液体。 50mM三羟甲基氨基甲烷氯化氢缓冲液(pH值8.0)含0.5mM DTT 10% 甘油

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Weiser WY., et al. (1989) Proc Natl Acad Sci. 86: 7522-26.;; Bernhagen J., et al. (1994) Biochemistry. 33: 14144-55.;; Bucala R., et al. (1996) FASEB J 10: 1607-1613.;;

> 98% by SDS-PAGE

十二烷基磺酸钠-PAGE

人类

激素&细胞因子

12 kDa (115aa) confirmed by MALDI-TOF

< 1 EU per 1ug of protein (determined by LAL method)

MPMFIVNTNV PRASVPDGFL SELTQQLAQA TGKPPQYIAV HVVPDQLMAF GGSSEPCALC SLHSIGKIGG AQNRSYSKLL CGLLAERLRI SPDRVYINYY DMNAANVGWN NSTFA

Non-Tagged

大肠杆菌

重组蛋白

P14174

MIF, MIF0801-10微克, MIF0801-20微克, MIF0801-50微克, MIF0801-100微克, MIF0801-250微克, MIF0801-500微克, MIF0801-1毫克, MIF0801-10, MIF0801-20, MIF0801-50, MIF0801-100, MIF0801-250, MIF0801-500, MIF0801-1

Garai J, et al. Tetralone derivatives are MIF tautomerase inhibitors and attenuate macrophage activation and amplify the hypothermic response in endotoxemic mice. (J Enzyme Inhib Med Chem. 2021){https://pubmed.ncbi.nlm.nih.gov/34225560/}