产品简要
公司名称 :
Neuromab
产品类型 :
抗体
产品名称 :
Kv1.2 K+ channel
目录 :
75-008
规格 :
100微克
价格 :
319美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
K14/16
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 127
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:200; 图 2
  • 免疫印迹; 小鼠; 1:1000; 图 3g
Saifetiarova J, Bhat M. Ablation of cytoskeletal scaffolding proteins, Band 4.1B and Whirlin, leads to cerebellar purkinje axon pathology and motor dysfunction. J Neurosci Res. 2019;97:313-331 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 2a
  • 免疫印迹; 小鼠; 图 2f
Yang Y, Arsenault J, Bah A, Krzeminski M, Fekete A, Chao O, et al. Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain. Mol Psychiatry. 2018;: pubmed 出版商
  • 免疫组化; 小鼠; 图 4c
Browne L, Smith K, Jagger D. Identification of Persistent and Resurgent Sodium Currents in Spiral Ganglion Neurons Cultured from the Mouse Cochlea. Eneuro. 2017;4: pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 3e
Taylor A, Saifetiarova J, Bhat M. Postnatal Loss of Neuronal and Glial Neurofascins Differentially Affects Node of Ranvier Maintenance and Myelinated Axon Function. Front Cell Neurosci. 2017;11:11 pubmed 出版商
  • 免疫组化; 小鼠; 1:500
Fernando R, Cotter L, Perrin Tricaud C, Berthelot J, Bartolami S, Pereira J, et al. Optimal myelin elongation relies on YAP activation by axonal growth and inhibition by Crb3/Hippo pathway. Nat Commun. 2016;7:12186 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7
Frank R, Komiyama N, Ryan T, Zhu F, O Dell T, Grant S. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation. Nat Commun. 2016;7:11264 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 2
Kawabata S, Takano M, Numasawa Kuroiwa Y, Itakura G, Kobayashi Y, Nishiyama Y, et al. Grafted Human iPS Cell-Derived Oligodendrocyte Precursor Cells Contribute to Robust Remyelination of Demyelinated Axons after Spinal Cord Injury. Stem Cell Reports. 2016;6:1-8 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2
Nieves Cintrón M, Nystoriak M, Prada M, Johnson K, Fayer W, Dell Acqua M, et al. Selective down-regulation of KV2.1 function contributes to enhanced arterial tone during diabetes. J Biol Chem. 2015;290:7918-29 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3b
Yokoi N, Fukata Y, Kase D, Miyazaki T, Jaegle M, Ohkawa T, et al. Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy. Nat Med. 2015;21:19-26 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Chang K, Zollinger D, Susuki K, Sherman D, Makara M, Brophy P, et al. Glial ankyrins facilitate paranodal axoglial junction assembly. Nat Neurosci. 2014;17:1673-81 pubmed 出版商
  • 免疫组化-自由浮动切片; 大鼠; 10 ug/ml
King A, Manning C, Trimmer J. A unique ion channel clustering domain on the axon initial segment of mammalian neurons. J Comp Neurol. 2014;522:2594-608 pubmed 出版商
Cordeiro S, Finol Urdaneta R, Köpfer D, Markushina A, Song J, French R, et al. Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric Kv1 channels. Proc Natl Acad Sci U S A. 2019;116:1059-1064 pubmed 出版商
Shi Q, Saifetiarova J, Taylor A, Bhat M. mTORC1 Activation by Loss of Tsc1 in Myelinating Glia Causes Downregulation of Quaking and Neurofascin 155 Leading to Paranodal Domain Disorganization. Front Cell Neurosci. 2018;12:201 pubmed 出版商
Susuki K, Zollinger D, Chang K, Zhang C, Huang C, Tsai C, et al. Glial βII Spectrin Contributes to Paranode Formation and Maintenance. J Neurosci. 2018;38:6063-6075 pubmed 出版商
Zhou L, Zhou L, Su L, Cao S, Xie Y, Wang N, et al. Celecoxib Ameliorates Seizure Susceptibility in Autosomal Dominant Lateral Temporal Epilepsy. J Neurosci. 2018;38:3346-3357 pubmed 出版商
Nguyen L, Anderson A. mTOR-dependent alterations of Kv1.1 subunit expression in the neuronal subset-specific Pten knockout mouse model of cortical dysplasia with epilepsy. Sci Rep. 2018;8:3568 pubmed 出版商
Huang C, Zhang C, Zollinger D, Leterrier C, Rasband M. An αII Spectrin-Based Cytoskeleton Protects Large-Diameter Myelinated Axons from Degeneration. J Neurosci. 2017;37:11323-11334 pubmed 出版商
Huang C, Zhang C, Ho T, Oses Prieto J, Burlingame A, Lalonde J, et al. αII Spectrin Forms a Periodic Cytoskeleton at the Axon Initial Segment and Is Required for Nervous System Function. J Neurosci. 2017;37:11311-11322 pubmed 出版商
Stange Marten A, Nabel A, Sinclair J, Fischl M, Alexandrova O, Wohlfrom H, et al. Input timing for spatial processing is precisely tuned via constant synaptic delays and myelination patterns in the auditory brainstem. Proc Natl Acad Sci U S A. 2017;114:E4851-E4858 pubmed 出版商
Saifetiarova J, Liu X, Taylor A, Li J, Bhat M. Axonal domain disorganization in Caspr1 and Caspr2 mutant myelinated axons affects neuromuscular junction integrity, leading to muscle atrophy. J Neurosci Res. 2017;95:1373-1390 pubmed 出版商
Hivert B, Pinatel D, Labasque M, Tricaud N, Goutebroze L, Faivre Sarrailh C. Assembly of juxtaparanodes in myelinating DRG culture: Differential clustering of the Kv1/Caspr2 complex and scaffolding protein 4.1B. Glia. 2016;64:840-52 pubmed 出版商
Baronas V, Yang R, Vilin Y, Kurata H. Determinants of frequency-dependent regulation of Kv1.2-containing potassium channels. Channels (Austin). 2016;10:158-66 pubmed 出版商
Peltola M, Kuja Panula J, Liuhanen J, Võikar V, Piepponen P, Hiekkalinna T, et al. AMIGO-Kv2.1 Potassium Channel Complex Is Associated With Schizophrenia-Related Phenotypes. Schizophr Bull. 2016;42:191-201 pubmed 出版商
Brügger V, Engler S, Pereira J, Ruff S, Horn M, Welzl H, et al. HDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with Neurofascins. PLoS Biol. 2015;13:e1002258 pubmed 出版商
Ford M, Alexandrova O, Cossell L, Stange Marten A, Sinclair J, Kopp Scheinpflug C, et al. Tuning of Ranvier node and internode properties in myelinated axons to adjust action potential timing. Nat Commun. 2015;6:8073 pubmed 出版商
Kole M, Qian J, Waase M, Klassen T, Chen T, Augustine G, et al. Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing. J Neurosci. 2015;35:11433-44 pubmed 出版商
Smith K, Browne L, Selwood D, McAlpine D, Jagger D. Phosphoinositide Modulation of Heteromeric Kv1 Channels Adjusts Output of Spiral Ganglion Neurons from Hearing Mice. J Neurosci. 2015;35:11221-32 pubmed 出版商
van Vliet A, Tannemaat M, van Duinen S, Verhaagen J, Malessy M, De Winter F. Human Neuroma-in-Continuity Contains Focal Deficits in Myelination. J Neuropathol Exp Neurol. 2015;74:901-11 pubmed 出版商
Hirono M, Ogawa Y, Misono K, Zollinger D, Trimmer J, Rasband M, et al. BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells. J Neurosci. 2015;35:7082-94 pubmed 出版商
Yoo S, Motari M, Susuki K, Prendergast J, Mountney A, Hurtado A, et al. Sialylation regulates brain structure and function. FASEB J. 2015;29:3040-53 pubmed 出版商
Syrbe S, Hedrich U, Riesch E, Djémié T, Müller S, Møller R, et al. De novo loss- or gain-of-function mutations in KCNA2 cause epileptic encephalopathy. Nat Genet. 2015;47:393-399 pubmed 出版商
Baronas V, McGuinness B, Brigidi G, Gomm Kolisko R, Vilin Y, Kim R, et al. Use-dependent activation of neuronal Kv1.2 channel complexes. J Neurosci. 2015;35:3515-24 pubmed 出版商
Miyazaki H, Oyama F, Inoue R, Aosaki T, Abe T, Kiyonari H, et al. Singular localization of sodium channel β4 subunit in unmyelinated fibres and its role in the striatum. Nat Commun. 2014;5:5525 pubmed 出版商
Salewski R, Mitchell R, Shen C, Fehlings M. Transplantation of neural stem cells clonally derived from embryonic stem cells promotes recovery after murine spinal cord injury. Stem Cells Dev. 2015;24:36-50 pubmed 出版商
Zenker J, Stettner M, Ruskamo S, Domènech Estévez E, Baloui H, Medard J, et al. A role of peripheral myelin protein 2 in lipid homeostasis of myelinating Schwann cells. Glia. 2014;62:1502-12 pubmed 出版商
Dufour M, Woodhouse A, Goaillard J. Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development. J Neurosci Res. 2014;92:981-99 pubmed 出版商
Lehnert S, Ford M, Alexandrova O, Hellmundt F, Felmy F, Grothe B, et al. Action potential generation in an anatomically constrained model of medial superior olive axons. J Neurosci. 2014;34:5370-84 pubmed 出版商
Kim K, Scholl E, Liu X, Shepherd A, Haeseleer F, Lee A. Localization and expression of CaBP1/caldendrin in the mouse brain. Neuroscience. 2014;268:33-47 pubmed 出版商
Bagchi B, Al Sabi A, Kaza S, Scholz D, O Leary V, Dolly J, et al. Disruption of myelin leads to ectopic expression of K(V)1.1 channels with abnormal conductivity of optic nerve axons in a cuprizone-induced model of demyelination. PLoS ONE. 2014;9:e87736 pubmed 出版商
Speca D, Ogata G, Mandikian D, Bishop H, Wiler S, Eum K, et al. Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability. Genes Brain Behav. 2014;13:394-408 pubmed 出版商
Fan L, Guan X, Wang W, Zhao J, Zhang H, Tiwari V, et al. Impaired neuropathic pain and preserved acute pain in rats overexpressing voltage-gated potassium channel subunit Kv1.2 in primary afferent neurons. Mol Pain. 2014;10:8 pubmed 出版商
Barry J, Gu Y, Jukkola P, O NEILL B, GU H, Mohler P, et al. Ankyrin-G directly binds to kinesin-1 to transport voltage-gated Na+ channels into axons. Dev Cell. 2014;28:117-31 pubmed 出版商
Liu Q, Lee E, Davis R. Heterogeneous intrinsic excitability of murine spiral ganglion neurons is determined by Kv1 and HCN channels. Neuroscience. 2014;257:96-110 pubmed 出版商
Green J, Yang J, Grati M, Kachar B, Bhat M. Whirlin, a cytoskeletal scaffolding protein, stabilizes the paranodal region and axonal cytoskeleton in myelinated axons. BMC Neurosci. 2013;14:96 pubmed 出版商
Kyle B, Ahrendt E, Braun A, Braun J. The large conductance, calcium-activated K+ (BK) channel is regulated by cysteine string protein. Sci Rep. 2013;3:2447 pubmed 出版商
Ruff C, Ye H, Legasto J, Stribbell N, Wang J, Zhang L, et al. Effects of adult neural precursor-derived myelination on axonal function in the perinatal congenitally dysmyelinated brain: optimizing time of intervention, developing accurate prediction models, and enhancing performance. J Neurosci. 2013;33:11899-915 pubmed 出版商
Wang W, Kim H, Lv P, TEMPEL B, Yamoah E. Association of the Kv1 family of K+ channels and their functional blueprint in the properties of auditory neurons as revealed by genetic and functional analyses. J Neurophysiol. 2013;110:1751-64 pubmed 出版商
Golan N, Kartvelishvily E, Spiegel I, Salomon D, Sabanay H, Rechav K, et al. Genetic deletion of Cadm4 results in myelin abnormalities resembling Charcot-Marie-Tooth neuropathy. J Neurosci. 2013;33:10950-61 pubmed 出版商
Zhao X, Tang Z, Zhang H, Atianjoh F, Zhao J, Liang L, et al. A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons. Nat Neurosci. 2013;16:1024-31 pubmed 出版商
Buffington S, Rasband M. Na+ channel-dependent recruitment of Nav?4 to axon initial segments and nodes of Ranvier. J Neurosci. 2013;33:6191-202 pubmed 出版商
Brewster A, Lugo J, Patil V, Lee W, Qian Y, Vanegas F, et al. Rapamycin reverses status epilepticus-induced memory deficits and dendritic damage. PLoS ONE. 2013;8:e57808 pubmed 出版商
Campanac E, Gasselin C, Baude A, Rama S, Ankri N, Debanne D. Enhanced intrinsic excitability in basket cells maintains excitatory-inhibitory balance in hippocampal circuits. Neuron. 2013;77:712-22 pubmed 出版商
Lee S, Sha D, Mohammed A, Asress S, Glass J, Chin L, et al. Motor and sensory neuropathy due to myelin infolding and paranodal damage in a transgenic mouse model of Charcot-Marie-Tooth disease type 1C. Hum Mol Genet. 2013;22:1755-70 pubmed 出版商
Ovsepian S, Steuber V, Le Berre M, O Hara L, O Leary V, Dolly J. A defined heteromeric KV1 channel stabilizes the intrinsic pacemaking and regulates the output of deep cerebellar nuclear neurons to thalamic targets. J Physiol. 2013;591:1771-91 pubmed 出版商
Takano M, Hikishima K, Fujiyoshi K, Shibata S, Yasuda A, Konomi T, et al. MRI characterization of paranodal junction failure and related spinal cord changes in mice. PLoS ONE. 2012;7:e52904 pubmed 出版商
Sanchez Ponce D, DeFelipe J, Garrido J, Munoz A. Developmental expression of Kv potassium channels at the axon initial segment of cultured hippocampal neurons. PLoS ONE. 2012;7:e48557 pubmed 出版商
Uchida N, Chen K, Dohse M, Hansen K, Dean J, Buser J, et al. Human neural stem cells induce functional myelination in mice with severe dysmyelination. Sci Transl Med. 2012;4:155ra136 pubmed 出版商
Sanchez J, Seidl A, Rubel E, Barria A. Control of neuronal excitability by NMDA-type glutamate receptors in early developing binaural auditory neurons. J Physiol. 2012;590:4801-18 pubmed 出版商
Seidl A, Sanchez J, Schecterson L, Tabor K, Wang Y, Kashima D, et al. Transgenic quail as a model for research in the avian nervous system: a comparative study of the auditory brainstem. J Comp Neurol. 2013;521:5-23 pubmed 出版商
Williams M, Fuchs J, Green J, Morielli A. Cellular mechanisms and behavioral consequences of Kv1.2 regulation in the rat cerebellum. J Neurosci. 2012;32:9228-37 pubmed 出版商
Oluich L, Stratton J, Xing Y, Ng S, Cate H, Sah P, et al. Targeted ablation of oligodendrocytes induces axonal pathology independent of overt demyelination. J Neurosci. 2012;32:8317-30 pubmed 出版商
Manning C, Bundros A, Trimmer J. Benefits and pitfalls of secondary antibodies: why choosing the right secondary is of primary importance. PLoS ONE. 2012;7:e38313 pubmed 出版商
Zenker J, Poirot O, de Preux Charles A, Arnaud E, Medard J, Lacroix C, et al. Altered distribution of juxtaparanodal kv1.2 subunits mediates peripheral nerve hyperexcitability in type 2 diabetes mellitus. J Neurosci. 2012;32:7493-8 pubmed 出版商
Glasscock E, Qian J, Kole M, Noebels J. Transcompartmental reversal of single fibre hyperexcitability in juxtaparanodal Kv1.1-deficient vagus nerve axons by activation of nodal KCNQ channels. J Physiol. 2012;590:3913-26 pubmed 出版商
Jukkola P, Lovett Racke A, Zamvil S, Gu C. K+ channel alterations in the progression of experimental autoimmune encephalomyelitis. Neurobiol Dis. 2012;47:280-93 pubmed 出版商
Powers B, Lasiene J, Plemel J, Shupe L, Perlmutter S, Tetzlaff W, et al. Axonal thinning and extensive remyelination without chronic demyelination in spinal injured rats. J Neurosci. 2012;32:5120-5 pubmed 出版商
Buttermore E, Piochon C, Wallace M, Philpot B, Hansel C, Bhat M. Pinceau organization in the cerebellum requires distinct functions of neurofascin in Purkinje and basket neurons during postnatal development. J Neurosci. 2012;32:4724-42 pubmed 出版商
Irani S, Pettingill P, Kleopa K, Schiza N, Waters P, Mazia C, et al. Morvan syndrome: clinical and serological observations in 29 cases. Ann Neurol. 2012;72:241-55 pubmed 出版商
Dhaunchak A, Becker C, Schulman H, de Faria O, Rajasekharan S, Banwell B, et al. Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis. Ann Neurol. 2012;71:601-13 pubmed 出版商
Deverman B, Patterson P. Exogenous leukemia inhibitory factor stimulates oligodendrocyte progenitor cell proliferation and enhances hippocampal remyelination. J Neurosci. 2012;32:2100-9 pubmed 出版商
Ivanovic A, Horresh I, Golan N, Spiegel I, Sabanay H, Frechter S, et al. The cytoskeletal adapter protein 4.1G organizes the internodes in peripheral myelinated nerves. J Cell Biol. 2012;196:337-44 pubmed 出版商
Shimoda Y, Koseki F, Itoh M, Toyoshima M, Watanabe K. A cis-complex of NB-2/contactin-5 with amyloid precursor-like protein 1 is localized on the presynaptic membrane. Neurosci Lett. 2012;510:148-53 pubmed 出版商
He S, Shao L, Rittase W, Bausch S. Increased Kv1 channel expression may contribute to decreased sIPSC frequency following chronic inhibition of NR2B-containing NMDAR. Neuropsychopharmacology. 2012;37:1338-56 pubmed 出版商
Kaphzan H, Buffington S, Jung J, Rasband M, Klann E. Alterations in intrinsic membrane properties and the axon initial segment in a mouse model of Angelman syndrome. J Neurosci. 2011;31:17637-48 pubmed 出版商
Peltola M, Kuja Panula J, Lauri S, Taira T, Rauvala H. AMIGO is an auxiliary subunit of the Kv2.1 potassium channel. EMBO Rep. 2011;12:1293-9 pubmed 出版商
Duflocq A, Chareyre F, Giovannini M, Couraud F, Davenne M. Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized by protein 4.1B. BMC Biol. 2011;9:66 pubmed 出版商
Joseph B, Thakali K, Pathan A, Kang E, Rusch N, Rhee S. Postsynaptic density-95 scaffolding of Shaker-type K? channels in smooth muscle cells regulates the diameter of cerebral arteries. J Physiol. 2011;589:5143-52 pubmed 出版商
Shakkottai V, do Carmo Costa M, Dell Orco J, Sankaranarayanan A, Wulff H, Paulson H. Early changes in cerebellar physiology accompany motor dysfunction in the polyglutamine disease spinocerebellar ataxia type 3. J Neurosci. 2011;31:13002-14 pubmed 出版商
Lysakowski A, Gaboyard Niay S, Calin Jageman I, Chatlani S, Price S, Eatock R. Molecular microdomains in a sensory terminal, the vestibular calyx ending. J Neurosci. 2011;31:10101-14 pubmed 出版商
Wykes R, Kalmbach A, Eliava M, Waters J. Changes in the physiology of CA1 hippocampal pyramidal neurons in preplaque CRND8 mice. Neurobiol Aging. 2012;33:1609-23 pubmed 出版商
Brandao K, Dell Acqua M, Levinson S. A-kinase anchoring protein 150 expression in a specific subset of TRPV1- and CaV 1.2-positive nociceptive rat dorsal root ganglion neurons. J Comp Neurol. 2012;520:81-99 pubmed 出版商
Hirtz J, Boesen M, Braun N, Deitmer J, Kramer F, Lohr C, et al. Cav1.3 calcium channels are required for normal development of the auditory brainstem. J Neurosci. 2011;31:8280-94 pubmed 出版商
Buttermore E, Dupree J, Cheng J, An X, Tessarollo L, Bhat M. The cytoskeletal adaptor protein band 4.1B is required for the maintenance of paranodal axoglial septate junctions in myelinated axons. J Neurosci. 2011;31:8013-24 pubmed 出版商
Shroff S, Mierzwa A, Scherer S, Peles E, Arévalo J, Chao M, et al. Paranodal permeability in "myelin mutants". Glia. 2011;59:1447-57 pubmed 出版商
Gu C, Gu Y. Clustering and activity tuning of Kv1 channels in myelinated hippocampal axons. J Biol Chem. 2011;286:25835-47 pubmed 出版商
Gross C, Yao X, Pong D, Jeromin A, Bassell G. Fragile X mental retardation protein regulates protein expression and mRNA translation of the potassium channel Kv4.2. J Neurosci. 2011;31:5693-8 pubmed 出版商
Vacher H, Yang J, Cerda O, Autillo Touati A, Dargent B, Trimmer J. Cdk-mediated phosphorylation of the Kv?2 auxiliary subunit regulates Kv1 channel axonal targeting. J Cell Biol. 2011;192:813-24 pubmed 出版商
Al Sabi A, Kaza S, Le Berre M, O Hara L, Bodeker M, Wang J, et al. Position-dependent attenuation by Kv1.6 of N-type inactivation of Kv1.4-containing channels. Biochem J. 2011;438:389-96 pubmed 出版商
Pohl H, Porcheri C, Mueggler T, Bachmann L, Martino G, Riethmacher D, et al. Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage. J Neurosci. 2011;31:1069-80 pubmed 出版商
Fulton S, Thibault D, Mendez J, Lahaie N, Tirotta E, Borrelli E, et al. Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow. J Biol Chem. 2011;286:9360-72 pubmed 出版商
Karcz A, Hennig M, Robbins C, Tempel B, Rubsamen R, Kopp Scheinpflug C. Low-voltage activated Kv1.1 subunits are crucial for the processing of sound source location in the lateral superior olive in mice. J Physiol. 2011;589:1143-57 pubmed 出版商
Song M, Moon Y, Shin S, Kim T, Yune T, Park K. Contribution of the delayed-rectifier potassium channel Kv2.1 to acute spinal cord injury in rats. BMB Rep. 2010;43:756-60 pubmed 出版商
Chang K, Susuki K, Dours Zimmermann M, Zimmermann D, Rasband M. Oligodendrocyte myelin glycoprotein does not influence node of ranvier structure or assembly. J Neurosci. 2010;30:14476-81 pubmed 出版商
Devaux J. The C-terminal domain of ßIV-spectrin is crucial for KCNQ2 aggregation and excitability at nodes of Ranvier. J Physiol. 2010;588:4719-30 pubmed 出版商
Shepherd M, Pomicter A, Velazco C, Henderson S, Dupree J. Paranodal reorganization results in the depletion of transverse bands in the aged central nervous system. Neurobiol Aging. 2012;33:203.e13-24 pubmed 出版商
Zhong X, Abd Elrahman K, Liao C, El Yazbi A, Walsh E, Walsh M, et al. Stromatoxin-sensitive, heteromultimeric Kv2.1/Kv9.3 channels contribute to myogenic control of cerebral arterial diameter. J Physiol. 2010;588:4519-37 pubmed 出版商
Crawford D, Mangiardi M, Song B, Patel R, Du S, Sofroniew M, et al. Oestrogen receptor beta ligand: a novel treatment to enhance endogenous functional remyelination. Brain. 2010;133:2999-3016 pubmed 出版商
Howell O, Rundle J, Garg A, Komada M, Brophy P, Reynolds R. Activated microglia mediate axoglial disruption that contributes to axonal injury in multiple sclerosis. J Neuropathol Exp Neurol. 2010;69:1017-1033 pubmed 出版商
Padmanabhan K, Urban N. Intrinsic biophysical diversity decorrelates neuronal firing while increasing information content. Nat Neurosci. 2010;13:1276-82 pubmed 出版商
Hovis K, Padmanabhan K, Urban N. A simple method of in vitro electroporation allows visualization, recording, and calcium imaging of local neuronal circuits. J Neurosci Methods. 2010;191:1-10 pubmed 出版商
Gazula V, Strumbos J, Mei X, Chen H, Rahner C, Kaczmarek L. Localization of Kv1.3 channels in presynaptic terminals of brainstem auditory neurons. J Comp Neurol. 2010;518:3205-20 pubmed 出版商
Mierzwa A, Arevalo J, Schiff R, Chao M, Rosenbluth J. Role of transverse bands in maintaining paranodal structure and axolemmal domain organization in myelinated nerve fibers: effect on longevity in dysmyelinated mutant mice. J Comp Neurol. 2010;518:2841-53 pubmed 出版商
Horresh I, Bar V, Kissil J, Peles E. Organization of myelinated axons by Caspr and Caspr2 requires the cytoskeletal adapter protein 4.1B. J Neurosci. 2010;30:2480-9 pubmed 出版商
Fukata Y, Lovero K, Iwanaga T, Watanabe A, Yokoi N, Tabuchi K, et al. Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy. Proc Natl Acad Sci U S A. 2010;107:3799-804 pubmed 出版商
Ogawa Y, Oses Prieto J, Kim M, Horresh I, Peles E, Burlingame A, et al. ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons. J Neurosci. 2010;30:1038-48 pubmed 出版商
Arnaud E, Zenker J, de Preux Charles A, Stendel C, Roos A, Medard J, et al. SH3TC2/KIAA1985 protein is required for proper myelination and the integrity of the node of Ranvier in the peripheral nervous system. Proc Natl Acad Sci U S A. 2009;106:17528-33 pubmed 出版商
Dours Zimmermann M, Maurer K, Rauch U, Stoffel W, Fassler R, Zimmermann D. Versican V2 assembles the extracellular matrix surrounding the nodes of ranvier in the CNS. J Neurosci. 2009;29:7731-42 pubmed 出版商
Tobin A, Joseph B, Al Kindi H, Albarwani S, Madden J, Nemetz L, et al. Loss of cerebrovascular Shaker-type K(+) channels: a shared vasodilator defect of genetic and renal hypertensive rats. Am J Physiol Heart Circ Physiol. 2009;297:H293-303 pubmed 出版商
Dupree J, Pomicter A. Myelin, DIGs, and membrane rafts in the central nervous system. Prostaglandins Other Lipid Mediat. 2010;91:118-29 pubmed 出版商
Teigler A, Komljenovic D, Draguhn A, Gorgas K, Just W. Defects in myelination, paranode organization and Purkinje cell innervation in the ether lipid-deficient mouse cerebellum. Hum Mol Genet. 2009;18:1897-908 pubmed 出版商
Ogawa Y, Rasband M. Proteomic analysis of optic nerve lipid rafts reveals new paranodal proteins. J Neurosci Res. 2009;87:3502-10 pubmed 出版商
Lorincz A, Nusser Z. Cell-type-dependent molecular composition of the axon initial segment. J Neurosci. 2008;28:14329-40 pubmed 出版商
Miller M, Okaty B, Nelson S. Region-specific spike-frequency acceleration in layer 5 pyramidal neurons mediated by Kv1 subunits. J Neurosci. 2008;28:13716-26 pubmed 出版商
Lonigro A, Devaux J. Disruption of neurofascin and gliomedin at nodes of Ranvier precedes demyelination in experimental allergic neuritis. Brain. 2009;132:260-73 pubmed 出版商
Cartwright T, Schwalbe R. Atypical sialylated N-glycan structures are attached to neuronal voltage-gated potassium channels. Biosci Rep. 2009;29:301-13 pubmed 出版商
Kim J, Nadal M, Clemens A, Baron M, Jung S, Misumi Y, et al. Kv4 accessory protein DPPX (DPP6) is a critical regulator of membrane excitability in hippocampal CA1 pyramidal neurons. J Neurophysiol. 2008;100:1835-47 pubmed 出版商
Windrem M, Schanz S, Guo M, Tian G, Washco V, Stanwood N, et al. Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse. Cell Stem Cell. 2008;2:553-65 pubmed 出版商
Johnston J, Griffin S, Baker C, Skrzypiec A, Chernova T, Forsythe I. Initial segment Kv2.2 channels mediate a slow delayed rectifier and maintain high frequency action potential firing in medial nucleus of the trapezoid body neurons. J Physiol. 2008;586:3493-509 pubmed 出版商
Ogawa Y, Horresh I, Trimmer J, Bredt D, Peles E, Rasband M. Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2. J Neurosci. 2008;28:5731-9 pubmed 出版商
Lasiene J, Shupe L, Perlmutter S, Horner P. No evidence for chronic demyelination in spared axons after spinal cord injury in a mouse. J Neurosci. 2008;28:3887-96 pubmed 出版商
Yang J, Vacher H, Park K, Clark E, Trimmer J. Trafficking-dependent phosphorylation of Kv1.2 regulates voltage-gated potassium channel cell surface expression. Proc Natl Acad Sci U S A. 2007;104:20055-60 pubmed
Chi X, Nicol G. Manipulation of the potassium channel Kv1.1 and its effect on neuronal excitability in rat sensory neurons. J Neurophysiol. 2007;98:2683-92 pubmed
Wenzel H, Vacher H, Clark E, Trimmer J, Lee A, Sapolsky R, et al. Structural consequences of Kcna1 gene deletion and transfer in the mouse hippocampus. Epilepsia. 2007;48:2023-46 pubmed
Ogiwara I, Miyamoto H, Morita N, Atapour N, Mazaki E, Inoue I, et al. Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation. J Neurosci. 2007;27:5903-14 pubmed
Vacher H, Mohapatra D, Misonou H, Trimmer J. Regulation of Kv1 channel trafficking by the mamba snake neurotoxin dendrotoxin K. FASEB J. 2007;21:906-14 pubmed
Gu C, Zhou W, Puthenveedu M, Xu M, Jan Y, Jan L. The microtubule plus-end tracking protein EB1 is required for Kv1 voltage-gated K+ channel axonal targeting. Neuron. 2006;52:803-16 pubmed
Van Wart A, Trimmer J, Matthews G. Polarized distribution of ion channels within microdomains of the axon initial segment. J Comp Neurol. 2007;500:339-52 pubmed
产品信息
TargetType :
K+ channels
靶标 :
Kv1.2 K+ channel
AccessionNum :
P16389
克隆 :
K14/16
HumanGeneName :
KCNA2
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/K14_16.pdf
抗体亚型 :
IgG2b
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
目录 :
75-008
更多信息或购买 :
公司信息
Neuromab
PO Box 1560 Davis, CA 95617-1560
info@antibodiesinc.com
http://neuromab.ucdavis.edu
800-824-8540 530-758-4400
公司总部: 美国