产品简要
公司名称 :
Neuromab
产品类型 :
抗体
产品名称 :
Shank3
目录 :
75-109
规格 :
100微克
价格 :
269美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
N69/46
反应物种 :
小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
文章摘录数: 9
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 大鼠; 1:100; 图 s1b
Harony Nicolas H, Kay M, du Hoffmann J, Klein M, Bozdagi Gunal O, Riad M, et al. Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat. elife. 2017;6: pubmed 出版商
  • 免疫印迹; 大鼠; 1:10
Farley M, Swulius M, Waxham M. Electron tomographic structure and protein composition of isolated rat cerebellar, hippocampal and cortical postsynaptic densities. Neuroscience. 2015;304:286-301 pubmed 出版商
  • 免疫沉淀; 小鼠; 图 1
Benthani F, Tran P, Currey N, Ng I, Giry Laterriere M, Carey L, et al. Proteogenomic Analysis Identifies a Novel Human SHANK3 Isoform. Int J Mol Sci. 2015;16:11522-30 pubmed 出版商
  • 免疫组化; 小鼠
Braude J, Vijayakumar S, Baumgarner K, Laurine R, Jones T, Jones S, et al. Deletion of Shank1 has minimal effects on the molecular composition and function of glutamatergic afferent postsynapses in the mouse inner ear. Hear Res. 2015;321:52-64 pubmed 出版商
Duffney L, Wei J, Cheng J, Liu W, Smith K, Kittler J, et al. Shank3 deficiency induces NMDA receptor hypofunction via an actin-dependent mechanism. J Neurosci. 2013;33:15767-78 pubmed 出版商
Durand C, Perroy J, Loll F, Perrais D, Fagni L, Bourgeron T, et al. SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism. Mol Psychiatry. 2012;17:71-84 pubmed 出版商
Bozdagi O, Sakurai T, Papapetrou D, Wang X, Dickstein D, Takahashi N, et al. Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication. Mol Autism. 2010;1:15 pubmed 出版商
Gauthier J, Champagne N, Lafreniere R, Xiong L, Spiegelman D, Brustein E, et al. De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia. Proc Natl Acad Sci U S A. 2010;107:7863-8 pubmed 出版商
Ma X, Kiraly D, Gaier E, Wang Y, Kim E, Levine E, et al. Kalirin-7 is required for synaptic structure and function. J Neurosci. 2008;28:12368-82 pubmed 出版商
产品信息
TargetType :
Scaffolds
靶标 :
Shank3
AccessionNum :
Q9JLU4
克隆 :
N69/46
HumanGeneName :
SHANK3
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N69_46.pdf
抗体亚型 :
IgG2b
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
ND
ValidationKO :
ND
目录 :
75-109
更多信息或购买 :
公司信息
Neuromab
PO Box 1560 Davis, CA 95617-1560
info@antibodiesinc.com
http://neuromab.ucdavis.edu
800-824-8540 530-758-4400
公司总部: 美国