产品简要
公司名称 :
Neuromab
产品类型 :
抗体
产品名称 :
Shank3
目录 :
75-344
规格 :
100微克
价格 :
269美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
N367/62
反应物种 :
小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 10
出版应用/物种/样本/稀释参考文献
  • 免疫沉淀; 小鼠; 图 1e
Brown E, Lautz J, Davis T, Gniffke E, VanSchoiack A, Neier S, et al. Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models. Mol Autism. 2018;9:48 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 5c
Qin L, Ma K, Wang Z, Hu Z, Matas E, Wei J, et al. Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition. Nat Neurosci. 2018;21:564-575 pubmed 出版商
  • 免疫印迹基因敲除验证; 大鼠; 1:100; 图 1b
Harony Nicolas H, Kay M, du Hoffmann J, Klein M, Bozdagi Gunal O, Riad M, et al. Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat. elife. 2017;6: pubmed 出版商
  • 免疫印迹; 小鼠; 图 7
Frank R, Komiyama N, Ryan T, Zhu F, O Dell T, Grant S. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation. Nat Commun. 2016;7:11264 pubmed 出版商
Ha H, Leal Ortiz S, Lalwani K, Kiyonaka S, Hamachi I, Mysore S, et al. Shank and Zinc Mediate an AMPA Receptor Subunit Switch in Developing Neurons. Front Mol Neurosci. 2018;11:405 pubmed 出版商
Drapeau E, Riad M, Kajiwara Y, Buxbaum J. Behavioral Phenotyping of an Improved Mouse Model of Phelan-McDermid Syndrome with a Complete Deletion of the Shank3 Gene. Eneuro. 2018;5: pubmed 出版商
Zhou Y, Kaiser T, Monteiro P, Zhang X, Van der Goes M, Wang D, et al. Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects. Neuron. 2016;89:147-62 pubmed 出版商
MacGillavry H, Kerr J, Kassner J, Frost N, Blanpied T. Shank-cortactin interactions control actin dynamics to maintain flexibility of neuronal spines and synapses. Eur J Neurosci. 2016;43:179-93 pubmed 出版商
Berg J, Lee C, Chen L, Galvan L, Cepeda C, Chen J, et al. JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse. Neuron. 2015;88:1173-1191 pubmed 出版商
Duffney L, Wei J, Cheng J, Liu W, Smith K, Kittler J, et al. Shank3 deficiency induces NMDA receptor hypofunction via an actin-dependent mechanism. J Neurosci. 2013;33:15767-78 pubmed 出版商
产品信息
TargetType :
Scaffolds
靶标 :
Shank3
AccessionNum :
Q9JLU4
克隆 :
N367/62
HumanGeneName :
SHANK3
DataSheetFileName :
neuromab.ucdavis.edu/datasheet/N367_62.pdf
抗体亚型 :
IgG2a
ValidationT :
Pass
ValidationBrIB :
Pass
ValidationBrIHC :
Pass
ValidationKO :
Pass
目录 :
75-344
更多信息或购买 :
公司信息
Neuromab
PO Box 1560 Davis, CA 95617-1560
info@antibodiesinc.com
http://neuromab.ucdavis.edu
800-824-8540 530-758-4400
公司总部: 美国