产品简要
公司名称 :
Nordic BioSite
产品类型 :
抗体
产品名称 :
CK17
目录 :
BSH-7311-1
规格 :
1毫升
价格 :
550美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
BS55
反应物种 :
人类
应用 :
免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
Nordic BioSite 产品网页
产品信息
目录代码 :
BSH-7311-1
产品名称 :
CK17
产品类型 :
Antibodies, Primary
宿主物种 :
小鼠
克隆性 :
单克隆
共轭 :
未共轭
克隆名称 :
BS55
规格 :
1毫升
标价(美元) :
550美元
产品描述 :
Anti-CK17, mouse monoclonal - Optibodies
背景 :
CK17, also known as KRT17, it is the type I intermediate filament chain keratin 17. It is found in nail beds, hair follicles, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. May play a role in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair.
别名 :
KRT17
缓冲液 :
TRIS with 0.03% sodium azide, pH7,2
应用摘要 :
IHC-P,IHC-Fr
储存 :
存放在4℃
更多信息或购买 :
Nordic BioSite 产品网页
公司信息
Nordic BioSite
support-us@nordicbiosite.com
www.nordicbiosite.com