Recombinant Human EMMPRIN/Basigin/CD147 (C-6His)
Recombinant Human EMMPRIN is produced by our Mammalian expression system and the target gene encoding Ala22-His205 is expressed with a 6His tag at the C-terminus.
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Lyophilized protein should be stored at Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen ß-chain. EMMPRIN is a transmembrane glycoprotein with different forms, resulting from different modes of glycosylation and N-terminal sequence variants. EMMPRIN can be expressed in breast cancer, oral squamous cell carcinoma, glioma, lymphoma, lung, bladder, and melanoma carcinomas cells. EMMPRIN promotes invasion, metastasis, growth, and survival of malignants cells, serves as a receptor for extracellular cyclophilinthe, may play a role in signal transduction.
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Basigin, 5F7, Collagenase Stimulatory Factor, Extracellular Matrix Metalloproteinase Inducer, EMMPRIN, Leukocyte Activation Antigen M6, OK Blood Group Antigen, Tumor Cell-Derived Collagenase Stimulatory Factor, TCSF, CD147, BSG
Greater than 95% as determined by reducing SDS-PAGE.
Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Novoprotein is a leading contract research biotech company dedicated solely to recombinant protein service. Novoprotein possesses advanced technology and extensive experience in the field and offers a comprehensive service portfolio, from protein expression, antibody production, protein modification, and protein crystallization. Novoprotein has accomplished over 1000 contract projects with an 85% success rate, and has developed a catalog of more than 600 recombinant proteins and cytokines since its inception in 2004. The capacity of the four well-established protein expression systems: E.coli, yeast, baculovirus/insect cell and mammalian cell systems, have reached gram scale. At Novoprotein, the stringent QC standard ensures the highest product quality. The strict confidentiality protocol protects the privacy of our clients. Our long term clients come from all over the world, including major pharmaceutical companies and world class research institutes.