产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
Langerin/CD207 Antibody (929F3.01)
目录 :
DDX0362P-100
规格 :
0.1毫克
价格 :
449美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
929F3.01
反应物种 :
人类, 小鼠, 大鼠
应用 :
酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 72
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 图 1d
Capucha T, Koren N, Nassar M, Heyman O, Nir T, Levy M, et al. Sequential BMP7/TGF-β1 signaling and microbiota instruct mucosal Langerhans cell differentiation. J Exp Med. 2018;215:481-500 pubmed 出版商
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Hasegawa T, Feng Z, Yan Z, Ngo K, Hosoi J, Demehri S. Reduction in Human Epidermal Langerhans Cells with Age Is Associated with Decline in CXCL14-Mediated Recruitment of CD14+ Monocytes. J Invest Dermatol. 2020;140:1327-1334 pubmed 出版商
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Nelson D, Marano R, Joo Y, Tian S, Patel B, Kaplan D, et al. BRAF V600E and Pten deletion in mice produces a histiocytic disorder with features of Langerhans cell histiocytosis. PLoS ONE. 2019;14:e0222400 pubmed 出版商
Yang Y, Zenke Y, Hirai T, Kaplan D. Keratinocyte-derived TGFβ is not required to maintain skin immune homeostasis. J Dermatol Sci. 2019;94:290-297 pubmed 出版商
Artym J, Kocieba M, Zaczynska E, Kochanowska I, Zimecki M, Kałas W, et al. Topically applied azaphenothiazines inhibit experimental psoriasis in mice. Int Immunopharmacol. 2018;59:276-286 pubmed 出版商
Artym J, Kocieba M, Zaczynska E, Zimecki M, Jeleń M, Morak Młodawska B, et al. Topically applied azaphenothiazines inhibit contact sensitivity to oxazolone in mice. Histol Histopathol. 2018;33:223-236 pubmed 出版商
Baptista M, Keszei M, Oliveira M, Sunahara K, Andersson J, Dahlberg C, et al. Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells. Nat Commun. 2016;7:12175 pubmed 出版商
Gibbs A, Leeansyah E, Introini A, Paquin Proulx D, Hasselrot K, Andersson E, et al. MAIT cells reside in the female genital mucosa and are biased towards IL-17 and IL-22 production in response to bacterial stimulation. Mucosal Immunol. 2017;10:35-45 pubmed 出版商
Chandra J, Miao Y, Romoff N, Frazer I. Epithelium Expressing the E7 Oncoprotein of HPV16 Attracts Immune-Modulatory Dendritic Cells to the Skin and Suppresses Their Antigen-Processing Capacity. PLoS ONE. 2016;11:e0152886 pubmed 出版商
Quispel W, Stegehuis Kamp J, Santos S, Egeler R, van Halteren A. Activated Conventional T-Cells Are Present in Langerhans Cell Histiocytosis Lesions Despite the Presence of Immune Suppressive Cytokines. J Interferon Cytokine Res. 2015;35:831-9 pubmed 出版商
Haid B, Schlögl D, Hermann M, Tripp C, Stoitzner P, Romani N, et al. Langerhans cells in the sebaceous gland of the murine skin. Exp Dermatol. 2015;24:899-901 pubmed 出版商
Weber C, Hainz K, Deressa T, Strandt H, Florindo Pinheiro D, Mittermair R, et al. Immune Reactions against Gene Gun Vaccines Are Differentially Modulated by Distinct Dendritic Cell Subsets in the Skin. PLoS ONE. 2015;10:e0128722 pubmed 出版商
Abd Warif N, Stoitzner P, Leggatt G, Mattarollo S, Frazer I, Hibma M. Langerhans cell homeostasis and activation is altered in hyperplastic human papillomavirus type 16 E7 expressing epidermis. PLoS ONE. 2015;10:e0127155 pubmed 出版商
Naik S, Bouladoux N, Linehan J, Han S, Harrison O, Wilhelm C, et al. Commensal-dendritic-cell interaction specifies a unique protective skin immune signature. Nature. 2015;520:104-8 pubmed 出版商
Flacher V, Tripp C, Mairhofer D, Steinman R, Stoitzner P, Idoyaga J, et al. Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance. EMBO Mol Med. 2014;6:1191-204 pubmed 出版商
Sparber F, Tripp C, Komenda K, Scheffler J, Clausen B, Huber L, et al. The late endosomal adaptor molecule p14 (LAMTOR2) regulates TGF?1-mediated homeostasis of Langerhans cells. J Invest Dermatol. 2015;135:119-129 pubmed 出版商
Hobday P, Auger J, Schuneman G, Haasken S, Verbeek J, Binstadt B. Fc? receptor III and Fc? receptor IV on macrophages drive autoimmune valvular carditis in mice. Arthritis Rheumatol. 2014;66:852-62 pubmed 出版商
Voisin B, Mairhofer D, Chen S, Stoitzner P, Mueller C, Flacher V. Anatomical distribution analysis reveals lack of Langerin+ dermal dendritic cells in footpads and tail of C57BL/6 mice. Exp Dermatol. 2014;23:354-6 pubmed 出版商
Knickelbein J, Buela K, Hendricks R. Antigen-presenting cells are stratified within normal human corneas and are rapidly mobilized during ex vivo viral infection. Invest Ophthalmol Vis Sci. 2014;55:1118-23 pubmed 出版商
Muto J, Morioka Y, Yamasaki K, Kim M, Garcia A, Carlin A, et al. Hyaluronan digestion controls DC migration from the skin. J Clin Invest. 2014;124:1309-19 pubmed
Elnekave M, Furmanov K, Shaul Y, Capucha T, Eli Berchoer L, Zelentsova K, et al. Second-generation Langerhans cells originating from epidermal precursors are essential for CD8+ T cell priming. J Immunol. 2014;192:1395-403 pubmed 出版商
Mollah S, Dobrin J, Feder R, Tse S, Matos I, Cheong C, et al. Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells. J Invest Dermatol. 2014;134:1265-1275 pubmed 出版商
Debeer S, Le Luduec J, Kaiserlian D, Laurent P, Nicolas J, Dubois B, et al. Comparative histology and immunohistochemistry of porcine versus human skin. Eur J Dermatol. 2013;23:456-66 pubmed 出版商
Mizraji G, Segev H, Wilensky A, Hovav A. Isolation, processing and analysis of murine gingival cells. J Vis Exp. 2013;:e50388 pubmed 出版商
Bachy V, Hervouet C, Becker P, Chorro L, Carlin L, Herath S, et al. Langerin negative dendritic cells promote potent CD8+ T-cell priming by skin delivery of live adenovirus vaccine microneedle arrays. Proc Natl Acad Sci U S A. 2013;110:3041-6 pubmed 出版商
Kellersch B, Brocker T. Langerhans cell homeostasis in mice is dependent on mTORC1 but not mTORC2 function. Blood. 2013;121:298-307 pubmed 出版商
Luckashenak N, Wähe A, Breit K, Brakebusch C, Brocker T. Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo. J Immunol. 2013;190:27-35 pubmed 出版商
Xu Y, Qi R, Chen W, Shi Y, Cui Z, Gao X, et al. Aging affects epidermal Langerhans cell development and function and alters their miRNA gene expression profile. Aging (Albany NY). 2012;4:742-54 pubmed
Mi Q, Xu Y, Wang H, Qi R, Dong Z, Zhou L. Deletion of microRNA miR-223 increases Langerhans cell cross-presentation. Int J Biochem Cell Biol. 2013;45:395-400 pubmed 出版商
Hitzler M, Majdic O, Heine G, Worm M, Ebert G, Luch A, et al. Human Langerhans cells control Th cells via programmed death-ligand 1 in response to bacterial stimuli and nickel-induced contact allergy. PLoS ONE. 2012;7:e46776 pubmed 出版商
Iram N, Mildner M, Prior M, Petzelbauer P, Fiala C, Hacker S, et al. Age-related changes in expression and function of Toll-like receptors in human skin. Development. 2012;139:4210-9 pubmed 出版商
Sperling T, Ołdak M, Walch Rückheim B, Wickenhauser C, Doorbar J, Pfister H, et al. Human papillomavirus type 8 interferes with a novel C/EBP?-mediated mechanism of keratinocyte CCL20 chemokine expression and Langerhans cell migration. PLoS Pathog. 2012;8:e1002833 pubmed 出版商
Arizon M, Nudel I, Segev H, Mizraji G, Elnekave M, Furmanov K, et al. Langerhans cells down-regulate inflammation-driven alveolar bone loss. Proc Natl Acad Sci U S A. 2012;109:7043-8 pubmed 出版商
Haley K, Igyarto B, Ortner D, Bobr A, Kashem S, Schenten D, et al. Langerhans cells require MyD88-dependent signals for Candida albicans response but not for contact hypersensitivity or migration. J Immunol. 2012;188:4334-9 pubmed 出版商
Segura E, Valladeau Guilemond J, Donnadieu M, Sastre Garau X, Soumelis V, Amigorena S. Characterization of resident and migratory dendritic cells in human lymph nodes. J Exp Med. 2012;209:653-60 pubmed 出版商
Flacher V, Tripp C, Haid B, Kissenpfennig A, Malissen B, Stoitzner P, et al. Skin langerin+ dendritic cells transport intradermally injected anti-DEC-205 antibodies but are not essential for subsequent cytotoxic CD8+ T cell responses. J Immunol. 2012;188:2146-55 pubmed 出版商
Langlet C, Tamoutounour S, Henri S, Luche H, Ardouin L, Gregoire C, et al. CD64 expression distinguishes monocyte-derived and conventional dendritic cells and reveals their distinct role during intramuscular immunization. J Immunol. 2012;188:1751-60 pubmed 出版商
Edelson B, Bradstreet T, Kc W, Hildner K, Herzog J, Sim J, et al. Batf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization. PLoS ONE. 2011;6:e25660 pubmed 出版商
Luche H, Ardouin L, Teo P, See P, Henri S, Merad M, et al. The earliest intrathymic precursors of CD8?(+) thymic dendritic cells correspond to myeloid-type double-negative 1c cells. Eur J Immunol. 2011;41:2165-75 pubmed 出版商
Mikami N, Matsushita H, Kato T, Kawasaki R, Sawazaki T, Kishimoto T, et al. Calcitonin gene-related peptide is an important regulator of cutaneous immunity: effect on dendritic cell and T cell functions. J Immunol. 2011;186:6886-93 pubmed 出版商
Kastenmüller K, Wille Reece U, Lindsay R, Trager L, Darrah P, Flynn B, et al. Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets. J Clin Invest. 2011;121:1782-96 pubmed 出版商
Rochereau N, Verrier B, Pin J, Genin C, Paul S. Phenotypic localization of distinct DC subsets in mouse Peyer Patch. Vaccine. 2011;29:3655-61 pubmed 出版商
Marquet F, Bonneau M, Pascale F, Urien C, Kang C, Schwartz Cornil I, et al. Characterization of dendritic cells subpopulations in skin and afferent lymph in the swine model. PLoS ONE. 2011;6:e16320 pubmed 出版商
Stoecklinger A, Eticha T, Mesdaghi M, Kissenpfennig A, Malissen B, Thalhamer J, et al. Langerin+ dermal dendritic cells are critical for CD8+ T cell activation and IgH ?-1 class switching in response to gene gun vaccines. J Immunol. 2011;186:1377-83 pubmed 出版商
Bobr A, Olvera Gomez I, Igyarto B, Haley K, Hogquist K, Kaplan D. Acute ablation of Langerhans cells enhances skin immune responses. J Immunol. 2010;185:4724-8 pubmed 出版商
Noordegraaf M, Flacher V, Stoitzner P, Clausen B. Functional redundancy of Langerhans cells and Langerin+ dermal dendritic cells in contact hypersensitivity. J Invest Dermatol. 2010;130:2752-9 pubmed 出版商
de Jong M, de Witte L, Taylor M, Geijtenbeek T. Herpes simplex virus type 2 enhances HIV-1 susceptibility by affecting Langerhans cell function. J Immunol. 2010;185:1633-41 pubmed 出版商
Poulin L, Salio M, Griessinger E, Anjos Afonso F, Craciun L, Chen J, et al. Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells. J Exp Med. 2010;207:1261-71 pubmed 出版商
Henri S, Poulin L, Tamoutounour S, Ardouin L, Guilliams M, de Bovis B, et al. CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells. J Exp Med. 2010;207:189-206 pubmed 出版商
Chorro L, Sarde A, Li M, Woollard K, Chambon P, Malissen B, et al. Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network. J Exp Med. 2009;206:3089-100 pubmed 出版商
Tripp C, Haid B, Flacher V, Sixt M, Peter H, Farkas J, et al. The lymph vessel network in mouse skin visualised with antibodies against the hyaluronan receptor LYVE-1. Immunobiology. 2008;213:715-28 pubmed 出版商
Nfon C, Dawson H, Toka F, Golde W. Langerhans cells in porcine skin. Vet Immunol Immunopathol. 2008;126:236-47 pubmed 出版商
Shklovskaya E, Roediger B, Fazekas de St Groth B. Epidermal and dermal dendritic cells display differential activation and migratory behavior while sharing the ability to stimulate CD4+ T cell proliferation in vivo. J Immunol. 2008;181:418-30 pubmed
Stoitzner P, Green L, Jung J, Price K, Atarea H, Kivell B, et al. Inefficient presentation of tumor-derived antigen by tumor-infiltrating dendritic cells. Cancer Immunol Immunother. 2008;57:1665-73 pubmed 出版商
Flacher V, Douillard P, Ait Yahia S, Stoitzner P, Clair Moninot V, Romani N, et al. Expression of langerin/CD207 reveals dendritic cell heterogeneity between inbred mouse strains. Immunology. 2008;123:339-47 pubmed 出版商
Bursch L, Wang L, Igyarto B, Kissenpfennig A, Malissen B, Kaplan D, et al. Identification of a novel population of Langerin+ dendritic cells. J Exp Med. 2007;204:3147-56 pubmed
Poulin L, Henri S, de Bovis B, Devilard E, Kissenpfennig A, Malissen B. The dermis contains langerin+ dendritic cells that develop and function independently of epidermal Langerhans cells. J Exp Med. 2007;204:3119-31 pubmed
Kaplan D, Li M, Jenison M, Shlomchik W, Flavell R, Shlomchik M. Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cells. J Exp Med. 2007;204:2545-52 pubmed
Stoecklinger A, Grieshuber I, Scheiblhofer S, Weiss R, Ritter U, Kissenpfennig A, et al. Epidermal langerhans cells are dispensable for humoral and cell-mediated immunity elicited by gene gun immunization. J Immunol. 2007;179:886-93 pubmed
Zimmerli S, Hauser C. Langerhans cells and lymph node dendritic cells express the tight junction component claudin-1. J Invest Dermatol. 2007;127:2381-90 pubmed
Dubrac S, Stoitzner P, Pirkebner D, Elentner A, Schoonjans K, Auwerx J, et al. Peroxisome proliferator-activated receptor-alpha activation inhibits Langerhans cell function. J Immunol. 2007;178:4362-72 pubmed
Kaplan D, Jenison M, Saeland S, Shlomchik W, Shlomchik M. Epidermal langerhans cell-deficient mice develop enhanced contact hypersensitivity. Immunity. 2005;23:611-20 pubmed
Douillard P, Stoitzner P, Tripp C, Clair Moninot V, Ait Yahia S, McLellan A, et al. Mouse lymphoid tissue contains distinct subsets of langerin/CD207 dendritic cells, only one of which represents epidermal-derived Langerhans cells. J Invest Dermatol. 2005;125:983-94 pubmed
Zhu J, Liu X, Xie C, Yan M, Yu Y, Sobel E, et al. T cell hyperactivity in lupus as a consequence of hyperstimulatory antigen-presenting cells. J Clin Invest. 2005;115:1869-78 pubmed
Abadie V, Badell E, Douillard P, Ensergueix D, Leenen P, Tanguy M, et al. Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes. Blood. 2005;106:1843-50 pubmed
Kissenpfennig A, Ait Yahia S, Clair Moninot V, Stössel H, Badell E, Bordat Y, et al. Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function. Mol Cell Biol. 2005;25:88-99 pubmed
Movassagh M, Spatz A, Davoust J, Lebecque S, Romero P, Pittet M, et al. Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma. Cancer Res. 2004;64:2192-8 pubmed
Valladeau J, Clair Moninot V, Dezutter Dambuyant C, Pin J, Kissenpfennig A, Mattei M, et al. Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues. J Immunol. 2002;168:782-92 pubmed
产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
DDX0362P-100
SKU号 :
DDX0362P-100
产品名称 :
Langerin/CD207 Antibody (929F3.01)
描述 :
The Langerin/CD207 Antibody (929F3.01) from Novus is a rat monoclonal antibody to Langerin/CD207. This antibody reacts with human, mouse, rat, porcine, equine. The Langerin/CD207 Antibody (929F3.01) has been validated for the following applications: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
靶标 :
Langerin/CD207
类别 :
一抗
单位尺寸 :
0.1毫克
缓冲液 :
三羟甲基氨基甲烷氯化钠(pH值8.0)
克隆性 :
单克隆
克隆 :
929F3.01
浓度 :
0.5毫克/毫升
共轭标签 :
未共轭
宿主 :
大鼠
免疫原 :
Langerin/CD207 was used as immunogen.
抗体亚型 :
IgG2a
纯度 :
离子交换层析
物种 :
Human, Mouse, Rat, Porcine, Equine
基因符号 :
CD207
应用 :
流式细胞仪, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学/免疫荧光, 免疫组化石蜡, 免疫组化冷冻
美元 :
449美元
别名 :
CD207 antigen, CD207 antigen, langerin, CD207 molecule, langerin, CLEC4KLangerhans cell specific c-type lectin, C-type lectin domain family 4 member K, C-type lectin domain family 4, member K, Langerin
储存 :
存放在-20C。 避免冻融循环
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。