This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
TDP-43/TARDBP抗体(2E2-D3)
目录 :
H00023435-M01
规格 :
0.1毫克
价格 :
399美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2E2-D3
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
文章摘录数: 169
参考文献
Cortese A, Simone R, Sullivan R, Vandrovcova J, Tariq H, Yan Y, et al. Biallelic expansion of an intronic repeat in RFC1 is a common cause of late-onset ataxia. Nat Genet. 2019;51:649-658 pubmed 出版商
Yin P, Guo X, Yang W, Yan S, Yang S, Zhao T, et al. Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains. Acta Neuropathol. 2019;137:919-937 pubmed 出版商
Aizawa H, Yamashita T, Kato H, Kimura T, Kwak S. Impaired Nucleoporins Are Present in Sporadic Amyotrophic Lateral Sclerosis Motor Neurons that Exhibit Mislocalization of the 43-kDa TAR DNA-Binding Protein. J Clin Neurol. 2019;15:62-67 pubmed 出版商
Gomez Tortosa E, Baradaran Heravi Y, González Álvarez V, Sainz M, Prieto Jurczynska C, Guerrero López R, et al. Presence of tau astrogliopathy in frontotemporal dementia caused by a novel Grn nonsense (Trp2*) mutation. Neurobiol Aging. 2019;76:214.e11-214.e15 pubmed 出版商
Steinacker P, Barschke P, Otto M. Biomarkers for diseases with TDP-43 pathology. Mol Cell Neurosci. 2019;97:43-59 pubmed 出版商
Neelagandan N, Gonnella G, Dang S, Janiesch P, Miller K, Küchler K, et al. TDP-43 enhances translation of specific mRNAs linked to neurodegenerative disease. Nucleic Acids Res. 2019;47:341-361 pubmed 出版商
Thammisetty S, Pedragosa J, Weng Y, Calon F, Planas A, Kriz J. Age-related deregulation of TDP-43 after stroke enhances NF-κB-mediated inflammation and neuronal damage. J Neuroinflammation. 2018;15:312 pubmed 出版商
Solomon D, Stepto A, Au W, Adachi Y, Diaper D, Hall R, et al. A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration. Brain. 2018;141:2908-2924 pubmed 出版商
Ramos Campoy O, Ávila Polo R, Grau Rivera O, Antonell A, Clarimon J, Rojas García R, et al. Systematic Screening of Ubiquitin/p62 Aggregates in Cerebellar Cortex Expands the Neuropathological Phenotype of the C9orf72 Expansion Mutation. J Neuropathol Exp Neurol. 2018;77:703-709 pubmed 出版商
Pozzi S, Thammisetty S, Julien J. Chronic Administration of Pimozide Fails to Attenuate Motor and Pathological Deficits in Two Mouse Models of Amyotrophic Lateral Sclerosis. Neurotherapeutics. 2018;15:715-727 pubmed 出版商
Andrés Benito P, Gelpi E, Povedano M, Santpere G, Ferrer I. Gene Expression Profile in Frontal Cortex in Sporadic Frontotemporal Lobar Degeneration-TDP. J Neuropathol Exp Neurol. 2018;77:608-627 pubmed 出版商
Scherz B, Rabl R, Flunkert S, Rohler S, Neddens J, Taub N, et al. mTh1 driven expression of hTDP-43 results in typical ALS/FTLD neuropathological symptoms. PLoS ONE. 2018;13:e0197674 pubmed 出版商
Endo R, Takashima N, Nekooki Machida Y, Komi Y, Hui K, Takao M, et al. TAR DNA-Binding Protein 43 and Disrupted in Schizophrenia 1 Coaggregation Disrupts Dendritic Local Translation and Mental Function in Frontotemporal Lobar Degeneration. Biol Psychiatry. 2018;84:509-521 pubmed 出版商
Deshaies J, Shkreta L, Moszczynski A, Sidibé H, Semmler S, Fouillen A, et al. TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis. Brain. 2018;141:1320-1333 pubmed 出版商
Grames M, Dayton R, Jackson K, Richard A, Lu X, Klein R. Cre-dependent AAV vectors for highly targeted expression of disease-related proteins and neurodegeneration in the substantia nigra. FASEB J. 2018;32:4420-4427 pubmed 出版商
Giannoccaro M, Bartoletti Stella A, Piras S, Casalena A, Oppi F, Ambrosetto G, et al. The First Historically Reported Italian Family with FTD/ALS Teaches a Lesson on C9orf72 RE: Clinical Heterogeneity and Oligogenic Inheritance. J Alzheimers Dis. 2018;62:687-697 pubmed 出版商
Feneberg E, Gray E, Ansorge O, Talbot K, Turner M. Towards a TDP-43-Based Biomarker for ALS and FTLD. Mol Neurobiol. 2018;55:7789-7801 pubmed 出版商
St Amour I, Turgeon A, Goupil C, Planel E, Hébert S. Co-occurrence of mixed proteinopathies in late-stage Huntington's disease. Acta Neuropathol. 2018;135:249-265 pubmed 出版商
Redaelli V, Rossi G, Maderna E, Kovacs G, Piccoli E, Caroppo P, et al. Alzheimer neuropathology without frontotemporal lobar degeneration hallmarks (TAR DNA-binding protein 43 inclusions) in missense progranulin mutation Cys139Arg. Brain Pathol. 2018;28:72-76 pubmed 出版商
Berson A, Sartoris A, Nativio R, Van Deerlin V, Toledo J, Porta S, et al. TDP-43 Promotes Neurodegeneration by Impairing Chromatin Remodeling. Curr Biol. 2017;27:3579-3590.e6 pubmed 出版商
Gregory J, Whiten D, Brown R, Barros T, Kumita J, Yerbury J, et al. Clusterin protects neurons against intracellular proteotoxicity. Acta Neuropathol Commun. 2017;5:81 pubmed 出版商
Borrego Écija S, Morgado J, Palencia Madrid L, Grau Rivera O, Rene R, Hernandez I, et al. Frontotemporal Dementia Caused by the P301L Mutation in the MAPT Gene: Clinicopathological Features of 13 Cases from the Same Geographical Origin in Barcelona, Spain. Dement Geriatr Cogn Disord. 2017;44:213-221 pubmed 出版商
Gelpi E, Carrato C, Grau López L, Becerra J, García Armengol R, Massuet A, et al. Incidental neuronal intermediate filament inclusion pathology: unexpected biopsy findings in a 37-year-old woman with epilepsy. Neuropathol Appl Neurobiol. 2017;43:636-640 pubmed 出版商
Chang J, Morton D. Drosophila lines with mutant and wild type human TDP-43 replacing the endogenous gene reveals phosphorylation and ubiquitination in mutant lines in the absence of viability or lifespan defects. PLoS ONE. 2017;12:e0180828 pubmed 出版商
Moreno F, Indakoetxea B, Barandiaran M, Caballero M, Gorostidi A, Calafell F, et al. The unexpected co-occurrence of GRN and MAPT p.A152T in Basque families: Clinical and pathological characteristics. PLoS ONE. 2017;12:e0178093 pubmed 出版商
Ash P, Stanford E, Al Abdulatif A, Ramirez Cardenas A, Ballance H, Boudeau S, et al. Dioxins and related environmental contaminants increase TDP-43 levels. Mol Neurodegener. 2017;12:35 pubmed 出版商
Koriath C, Bocchetta M, Brotherhood E, Woollacott I, Norsworthy P, Simon Sanchez J, et al. The clinical, neuroanatomical, and neuropathologic phenotype of TBK1-associated frontotemporal dementia: A longitudinal case report. Alzheimers Dement (Amst). 2017;6:75-81 pubmed 出版商
Wang W, Arakawa H, Wang L, Okolo O, Siedlak S, Jiang Y, et al. Motor-Coordinative and Cognitive Dysfunction Caused by Mutant TDP-43 Could Be Reversed by Inhibiting Its Mitochondrial Localization. Mol Ther. 2017;25:127-139 pubmed 出版商
van der Zee J, Gijselinck I, Van Mossevelde S, Perrone F, Dillen L, Heeman B, et al. TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis. Hum Mutat. 2017;38:297-309 pubmed 出版商
Dutta K, Patel P, Rahimian R, Phaneuf D, Julien J. Withania somnifera Reverses Transactive Response DNA Binding Protein 43 Proteinopathy in a Mouse Model of Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration. Neurotherapeutics. 2017;14:447-462 pubmed 出版商
Gelpi E, Hoftberger R, Graus F, Ling H, Holton J, Dawson T, et al. Neuropathological criteria of anti-IgLON5-related tauopathy. Acta Neuropathol. 2016;132:531-43 pubmed 出版商
Wang W, Wang L, Lu J, Siedlak S, Fujioka H, Liang J, et al. The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity. Nat Med. 2016;22:869-78 pubmed 出版商
Ansoleaga B, Garcia Esparcia P, Llorens F, Hernández Ortega K, Carmona Tech M, Antonio Del Río J, et al. Altered Mitochondria, Protein Synthesis Machinery, and Purine Metabolism Are Molecular Contributors to the Pathogenesis of Creutzfeldt-Jakob Disease. J Neuropathol Exp Neurol. 2016;: pubmed
Koyama A, Sugai A, Kato T, Ishihara T, Shiga A, Toyoshima Y, et al. Increased cytoplasmic TARDBP mRNA in affected spinal motor neurons in ALS caused by abnormal autoregulation of TDP-43. Nucleic Acids Res. 2016;44:5820-36 pubmed 出版商
Mashiko T, Sakashita E, Kasashima K, Tominaga K, Kuroiwa K, Nozaki Y, et al. Developmentally Regulated RNA-binding Protein 1 (Drb1)/RNA-binding Motif Protein 45 (RBM45), a Nuclear-Cytoplasmic Trafficking Protein, Forms TAR DNA-binding Protein 43 (TDP-43)-mediated Cytoplasmic Aggregates. J Biol Chem. 2016;291:14996-5007 pubmed 出版商
De Marco G, Lomartire A, Calvo A, Risso A, De Luca E, Mostert M, et al. Monocytes of patients with amyotrophic lateral sclerosis linked to gene mutations display altered TDP-43 subcellular distribution. Neuropathol Appl Neurobiol. 2017;43:133-153 pubmed 出版商
Williams K, Topp S, Yang S, Smith B, Fifita J, Warraich S, et al. CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia. Nat Commun. 2016;7:11253 pubmed 出版商
Jiang L, Zhao J, Yin X, He W, Yang H, Che M, et al. Two mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation and inclusion formation. Sci Rep. 2016;6:23928 pubmed 出版商
Solla P, Grau Rivera O, Gelpi E, Marrosu F, Marti M. Pisa syndrome in a patient with pathologically confirmed Parkinson's disease. Neuropathol Appl Neurobiol. 2016;42:654-658 pubmed 出版商
Wang G, Yang H, Yan S, Wang C, Liu X, Zhao B, et al. Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain. Mol Neurodegener. 2015;10:42 pubmed 出版商
Lynch D, Jaunmuktane Z, Sheerin U, Phadke R, Brandner S, Milonas I, et al. Hereditary leukoencephalopathy with axonal spheroids: a spectrum of phenotypes from CNS vasculitis to parkinsonism in an adult onset leukodystrophy series. J Neurol Neurosurg Psychiatry. 2016;87:512-9 pubmed 出版商
Goossens J, Vanmechelen E, Trojanowski J, Lee V, Van Broeckhoven C, van der Zee J, et al. TDP-43 as a possible biomarker for frontotemporal lobar degeneration: a systematic review of existing antibodies. Acta Neuropathol Commun. 2015;3:15 pubmed 出版商
Xiao S, Sanelli T, Chiang H, Sun Y, Chakrabartty A, Keith J, et al. Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death. Acta Neuropathol. 2015;130:49-61 pubmed 出版商
Rosenbohm A, Buckert D, Gerischer N, Walcher T, Kassubek J, Rottbauer W, et al. Early diagnosis of cardiac involvement in idiopathic inflammatory myopathy by cardiac magnetic resonance tomography. J Neurol. 2015;262:949-56 pubmed 出版商
Saldi T, Ash P, Wilson G, Gonzales P, Garrido Lecca A, Roberts C, et al. TDP-1, the Caenorhabditis elegans ortholog of TDP-43, limits the accumulation of double-stranded RNA. EMBO J. 2014;33:2947-66 pubmed 出版商
Alafuzoff I, Pikkarainen M, Neumann M, Arzberger T, Al Sarraj S, Bodi I, et al. Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium. J Neural Transm (Vienna). 2015;122:957-72 pubmed 出版商
Yarchoan M, Toledo J, Lee E, Arvanitakis Z, Kazi H, Han L, et al. Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies. Acta Neuropathol. 2014;128:679-89 pubmed 出版商
Kara E, Kiely A, Proukakis C, Giffin N, Love S, Hehir J, et al. A 6.4 Mb duplication of the ?-synuclein locus causing frontotemporal dementia and Parkinsonism: phenotype-genotype correlations. JAMA Neurol. 2014;71:1162-71 pubmed 出版商
Robinson A, Thompson J, Weedon L, Rollinson S, Pickering Brown S, Snowden J, et al. No interaction between tau and TDP-43 pathologies in either frontotemporal lobar degeneration or motor neurone disease. Neuropathol Appl Neurobiol. 2014;40:844-54 pubmed 出版商
Wenqiang C, Lonskaya I, Hebron M, Ibrahim Z, Olszewski R, Neale J, et al. Parkin-mediated reduction of nuclear and soluble TDP-43 reverses behavioral decline in symptomatic mice. Hum Mol Genet. 2014;23:4960-9 pubmed 出版商
Hans F, Fiesel F, Strong J, J ckel S, Rasse T, Geisler S, et al. UBE2E ubiquitin-conjugating enzymes and ubiquitin isopeptidase Y regulate TDP-43 protein ubiquitination. J Biol Chem. 2014;289:19164-79 pubmed 出版商
Ohta Y, Tremblay C, Schneider J, Bennett D, Calon F, Julien J. Interaction of transactive response DNA binding protein 43 with nuclear factor ?B in mild cognitive impairment with episodic memory deficits. Acta Neuropathol Commun. 2014;2:37 pubmed 出版商
Carlomagno Y, Zhang Y, Davis M, Lin W, Cook C, Dunmore J, et al. Casein kinase II induced polymerization of soluble TDP-43 into filaments is inhibited by heat shock proteins. PLoS ONE. 2014;9:e90452 pubmed 出版商
Araki W, Minegishi S, Motoki K, Kume H, Hohjoh H, Araki Y, et al. Disease-associated mutations of TDP-43 promote turnover of the protein through the proteasomal pathway. Mol Neurobiol. 2014;50:1049-58 pubmed 出版商
Cortese A, Plagnol V, Brady S, Simone R, Lashley T, Acevedo Arozena A, et al. Widespread RNA metabolism impairment in sporadic inclusion body myositis TDP43-proteinopathy. Neurobiol Aging. 2014;35:1491-8 pubmed 出版商
De Marco G, Lomartire A, Mandili G, Lupino E, Buccinnà B, Ramondetti C, et al. Reduced cellular Ca(2+) availability enhances TDP-43 cleavage by apoptotic caspases. Biochim Biophys Acta. 2014;1843:725-34 pubmed 出版商
Gelpi E, Navarro Otano J, Tolosa E, Gaig C, Compta Y, Rey M, et al. Multiple organ involvement by alpha-synuclein pathology in Lewy body disorders. Mov Disord. 2014;29:1010-8 pubmed 出版商
Yan S, Wang C, Wei W, Gaertig M, Lai L, Li S, et al. TDP-43 causes differential pathology in neuronal versus glial cells in the mouse brain. Hum Mol Genet. 2014;23:2678-93 pubmed 出版商
Balasa M, Gelpi E, Rey M, Vila J, Ramió Torrentà L, Quiles Granado A, et al. Clinical and neuropathological variability in clinically isolated central nervous system Whipple's disease. Brain Pathol. 2014;24:230-8 pubmed 出版商
Walker A, Soo K, Sundaramoorthy V, Parakh S, Ma Y, Farg M, et al. ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formation. PLoS ONE. 2013;8:e81170 pubmed 出版商
Suarez Calvet M, Dols Icardo O, Lladó A, Sanchez Valle R, Hernandez I, Amer G, et al. Plasma phosphorylated TDP-43 levels are elevated in patients with frontotemporal dementia carrying a C9orf72 repeat expansion or a GRN mutation. J Neurol Neurosurg Psychiatry. 2014;85:684-91 pubmed 出版商
Hebron M, Chen W, Miessau M, Lonskaya I, Moussa C. Parkin reverses TDP-43-induced cell death and failure of amino acid homeostasis. J Neurochem. 2014;129:350-61 pubmed 出版商
Iovino M, Pfisterer U, Holton J, Lashley T, Swingler R, Calò L, et al. The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons. Acta Neuropathol. 2014;127:283-95 pubmed 出版商
Lashley T, Rohrer J, Mahoney C, Gordon E, Beck J, Mead S, et al. A pathogenic progranulin mutation and C9orf72 repeat expansion in a family with frontotemporal dementia. Neuropathol Appl Neurobiol. 2014;40:502-13 pubmed 出版商
Grau Rivera O, Gelpi E, Rey M, Valldeoriola F, Tolosa E, Compta Y, et al. Prominent psychiatric symptoms in patients with Parkinson's disease and concomitant argyrophilic grain disease. J Neurol. 2013;260:3002-9 pubmed 出版商
Medina D, Orr M, Oddo S. Accumulation of C-terminal fragments of transactive response DNA-binding protein 43 leads to synaptic loss and cognitive deficits in human TDP-43 transgenic mice. Neurobiol Aging. 2014;35:79-87 pubmed 出版商
Xu Y, Prudencio M, Hubbard J, Tong J, Whitelaw E, Jansen West K, et al. The pathological phenotypes of human TDP-43 transgenic mouse models are independent of downregulation of mouse Tdp-43. PLoS ONE. 2013;8:e69864 pubmed 出版商
Prell T, Grosskreutz J. The involvement of the cerebellum in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener. 2013;14:507-15 pubmed 出版商
Finsterer J, Stollberger C, Kovacs G. Asymptomatic hyper-creatine-kinase-emia as sole manifestation of inclusion body myositis. Neurol Int. 2013;5:34-6 pubmed 出版商
Nishimoto Y, Nakagawa S, Hirose T, Okano H, Takao M, Shibata S, et al. The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis. Mol Brain. 2013;6:31 pubmed 出版商
Mundiñano I, Hernandez M, Dicaudo C, Ordóñez C, Marcilla I, Tuñon M, et al. Reduced cholinergic olfactory centrifugal inputs in patients with neurodegenerative disorders and MPTP-treated monkeys. Acta Neuropathol. 2013;126:411-25 pubmed 出版商
Tong J, Huang C, Bi F, Wu Q, Huang B, Liu X, et al. Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats. EMBO J. 2013;32:1917-26 pubmed 出版商
Gelpi E, Cullel F, Navarro Otano J, Lladó A. Globular glial-like inclusions in a patient with advanced Alzheimer's disease. Acta Neuropathol. 2013;126:155-7 pubmed 出版商
Dayton R, Gitcho M, Orchard E, Wilson J, Wang D, Cain C, et al. Selective forelimb impairment in rats expressing a pathological TDP-43 25?kDa C-terminal fragment to mimic amyotrophic lateral sclerosis. Mol Ther. 2013;21:1324-34 pubmed 出版商
Iyer A, Prabowo A, Anink J, Spliet W, Van Rijen P, Aronica E. Cell injury and premature neurodegeneration in focal malformations of cortical development. Brain Pathol. 2014;24:1-17 pubmed 出版商
Iranzo A, Tolosa E, Gelpi E, Molinuevo J, Valldeoriola F, Serradell M, et al. Neurodegenerative disease status and post-mortem pathology in idiopathic rapid-eye-movement sleep behaviour disorder: an observational cohort study. Lancet Neurol. 2013;12:443-53 pubmed 出版商
Bi F, Huang C, Tong J, Qiu G, Huang B, Wu Q, et al. Reactive astrocytes secrete lcn2 to promote neuron death. Proc Natl Acad Sci U S A. 2013;110:4069-74 pubmed 出版商
Doherty K, Rohrer J, Lees A, Holton J, Warren J. Primary progressive aphasia with parkinsonism. Mov Disord. 2013;28:741-6 pubmed 出版商
Hebron M, Lonskaya I, Sharpe K, Weerasinghe P, Algarzae N, Shekoyan A, et al. Parkin ubiquitinates Tar-DNA binding protein-43 (TDP-43) and promotes its cytosolic accumulation via interaction with histone deacetylase 6 (HDAC6). J Biol Chem. 2013;288:4103-15 pubmed 出版商
Swarup V, Audet J, Phaneuf D, Kriz J, Julien J. Abnormal regenerative responses and impaired axonal outgrowth after nerve crush in TDP-43 transgenic mouse models of amyotrophic lateral sclerosis. J Neurosci. 2012;32:18186-95 pubmed 出版商
Watanabe S, Kaneko K, Yamanaka K. Accelerated disease onset with stabilized familial amyotrophic lateral sclerosis (ALS)-linked mutant TDP-43 proteins. J Biol Chem. 2013;288:3641-54 pubmed 出版商
Tong J, Huang C, Bi F, Wu Q, Huang B, Zhou H. XBP1 depletion precedes ubiquitin aggregation and Golgi fragmentation in TDP-43 transgenic rats. J Neurochem. 2012;123:406-16 pubmed 出版商
Lopez Gonzalez I, Carmona M, Blanco R, Luna Munoz J, Martínez Mandonado A, Mena R, et al. Characterization of thorn-shaped astrocytes in white matter of temporal lobe in Alzheimer's disease brains. Brain Pathol. 2013;23:144-53 pubmed 出版商
Verstraete E, Kuiperij H, van Blitterswijk M, Veldink J, Schelhaas H, van den Berg L, et al. TDP-43 plasma levels are higher in amyotrophic lateral sclerosis. Amyotroph Lateral Scler. 2012;13:446-51 pubmed 出版商
Gelpi E, Soler Insa J, Parchi P, Saverioni D, Yague J, Nos C, et al. Atypical neuropathological sCJD-MM phenotype with abundant white matter Kuru-type plaques sparing the cerebellar cortex. Neuropathology. 2013;33:204-8 pubmed 出版商
Colom Cadena M, Gelpi E, Marti M, Charif S, Dols Icardo O, Blesa R, et al. MAPT H1 haplotype is associated with enhanced ?-synuclein deposition in dementia with Lewy bodies. Neurobiol Aging. 2013;34:936-42 pubmed 出版商
Vilas D, Marti M, Botta Orfila T, Colom Cadena M, Gelpi E. Pick's pathology in Parkinson's disease with dementia. Neuropathol Appl Neurobiol. 2012;38:737-43 pubmed 出版商
Echávarri C, Burgmans S, Caballero M, Garcia Bragado F, Verhey F, Uylings H. Co-occurrence of different pathologies in dementia: implications for dementia diagnosis. J Alzheimers Dis. 2012;30:909-17 pubmed 出版商
Herman A, Khandelwal P, Rebeck G, Moussa C. Wild type TDP-43 induces neuro-inflammation and alters APP metabolism in lentiviral gene transfer models. Exp Neurol. 2012;235:297-305 pubmed 出版商
Troakes C, Maekawa S, Wijesekera L, Rogelj B, Siklós L, Bell C, et al. An MND/ALS phenotype associated with C9orf72 repeat expansion: abundant p62-positive, TDP-43-negative inclusions in cerebral cortex, hippocampus and cerebellum but without associated cognitive decline. Neuropathology. 2012;32:505-14 pubmed 出版商
Dayton R, Wang D, Cain C, Schrott L, Ramirez J, King M, et al. Frontotemporal lobar degeneration-related proteins induce only subtle memory-related deficits when bilaterally overexpressed in the dorsal hippocampus. Exp Neurol. 2012;233:807-14 pubmed 出版商
Huang C, Tong J, Bi F, Zhou H, Xia X. Mutant TDP-43 in motor neurons promotes the onset and progression of ALS in rats. J Clin Invest. 2012;122:107-18 pubmed 出版商
Pirici D, Pirici I, Mogoanta L, Mărgăritescu O, Tudorică V, Margaritescu C, et al. Matrix metalloproteinase-9 expression in the nuclear compartment of neurons and glial cells in aging and stroke. Neuropathology. 2012;32:492-504 pubmed 出版商
Tsuji H, Nonaka T, Yamashita M, Masuda Suzukake M, Kametani F, Akiyama H, et al. Epitope mapping of antibodies against TDP-43 and detection of protease-resistant fragments of pathological TDP-43 in amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Biochem Biophys Res Commun. 2012;417:116-21 pubmed 出版商
Fiesel F, Weber S, Supper J, Zell A, Kahle P. TDP-43 regulates global translational yield by splicing of exon junction complex component SKAR. Nucleic Acids Res. 2012;40:2668-82 pubmed 出版商
Antonell A, Gelpi E, Sanchez Valle R, Martinez R, Molinuevo J, Lladó A. Breakpoint sequence analysis of an A?PP locus duplication associated with autosomal dominant Alzheimer's disease and severe cerebral amyloid angiopathy. J Alzheimers Dis. 2012;28:303-8 pubmed 出版商
Thom M, Liu J, Thompson P, Phadke R, Narkiewicz M, Martinian L, et al. Neurofibrillary tangle pathology and Braak staging in chronic epilepsy in relation to traumatic brain injury and hippocampal sclerosis: a post-mortem study. Brain. 2011;134:2969-81 pubmed 出版商
Wang J, Brent J, Tomlinson A, Shneider N, McCabe B. The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span. J Clin Invest. 2011;121:4118-26 pubmed 出版商
Swarup V, Phaneuf D, Bareil C, Robertson J, Rouleau G, Kriz J, et al. Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments. Brain. 2011;134:2610-26 pubmed 出版商
Martínez Sáez E, Gelpi E, Rey M, Ferrer I, Ribalta T, Botta Orfila T, et al. Hirano body-rich subtypes of Creutzfeldt-Jakob disease. Neuropathol Appl Neurobiol. 2012;38:153-61 pubmed 出版商
Azizi A, Li L, Strobel T, Chen W, Slavc I, Lubec G. Identification of c-myc-dependent proteins in the medulloblastoma cell line D425Med. Amino Acids. 2012;42:2149-63 pubmed 出版商
López Hernández T, Sirisi S, Capdevila Nortes X, Montolio M, Fernández Dueñas V, Scheper G, et al. Molecular mechanisms of MLC1 and GLIALCAM mutations in megalencephalic leukoencephalopathy with subcortical cysts. Hum Mol Genet. 2011;20:3266-77 pubmed 出版商
Rusina R, Kovacs G, Fiala J, Hort J, Ridzon P, Holmerová I, et al. FTLD-TDP with motor neuron disease, visuospatial impairment and a progressive supranuclear palsy-like syndrome: broadening the clinical phenotype of TDP-43 proteinopathies. A report of three cases. BMC Neurol. 2011;11:50 pubmed 出版商
Mundiñano I, Caballero M, Ordóñez C, Hernandez M, Dicaudo C, Marcilla I, et al. Increased dopaminergic cells and protein aggregates in the olfactory bulb of patients with neurodegenerative disorders. Acta Neuropathol. 2011;122:61-74 pubmed 出版商
Pikkarainen M, Hartikainen P, Soininen H, Alafuzoff I. Distribution and pattern of pathology in subjects with familial or sporadic late-onset cerebellar ataxia as assessed by p62/sequestosome immunohistochemistry. Cerebellum. 2011;10:720-31 pubmed 出版商
Hartikainen P, Pikkarainen M, Hanninen T, Soininen H, Alafuzoff I. Unusual clinical presentation and neuropathology in two subjects with fused-in sarcoma (FUS) positive inclusions. Neuropathology. 2012;32:60-8 pubmed 出版商
Che M, Jiang Y, Xie Y, Jiang L, Hu H. Aggregation of the 35-kDa fragment of TDP-43 causes formation of cytoplasmic inclusions and alteration of RNA processing. FASEB J. 2011;25:2344-53 pubmed 出版商
Tian T, Huang C, Tong J, Yang M, Zhou H, Xia X. TDP-43 potentiates alpha-synuclein toxicity to dopaminergic neurons in transgenic mice. Int J Biol Sci. 2011;7:234-43 pubmed
Herman A, Khandelwal P, Stanczyk B, Rebeck G, Moussa C. ?-amyloid triggers ALS-associated TDP-43 pathology in AD models. Brain Res. 2011;1386:191-9 pubmed 出版商
Lashley T, Holton J, Revesz T. TDP-43 pathology may occur in the BRI2 gene-related dementias. Acta Neuropathol. 2011;121:559-60 pubmed 出版商
Rauramaa T, Pikkarainen M, Englund E, Ince P, Jellinger K, Paetau A, et al. TAR-DNA binding protein-43 and alterations in the hippocampus. J Neural Transm (Vienna). 2011;118:683-9 pubmed 出版商
Noto Y, Shibuya K, Sato Y, Kanai K, Misawa S, Sawai S, et al. Elevated CSF TDP-43 levels in amyotrophic lateral sclerosis: specificity, sensitivity, and a possible prognostic value. Amyotroph Lateral Scler. 2011;12:140-3 pubmed 出版商
De Marco G, Lupino E, Calvo A, Moglia C, Buccinnà B, Grifoni S, et al. Cytoplasmic accumulation of TDP-43 in circulating lymphomonocytes of ALS patients with and without TARDBP mutations. Acta Neuropathol. 2011;121:611-22 pubmed 出版商
Higashi S, Tsuchiya Y, Araki T, Wada K, Kabuta T. TDP-43 physically interacts with amyotrophic lateral sclerosis-linked mutant CuZn superoxide dismutase. Neurochem Int. 2010;57:906-13 pubmed 出版商
Wang D, Dayton R, Henning P, Cain C, Zhao L, Schrott L, et al. Expansive gene transfer in the rat CNS rapidly produces amyotrophic lateral sclerosis relevant sequelae when TDP-43 is overexpressed. Mol Ther. 2010;18:2064-74 pubmed 出版商
Hoftberger R, Fink S, Aboul Enein F, Botond G, Olah J, Berki T, et al. Tubulin polymerization promoting protein (TPPP/p25) as a marker for oligodendroglial changes in multiple sclerosis. Glia. 2010;58:1847-57 pubmed 出版商
Shan X, Chiang P, Price D, Wong P. Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice. Proc Natl Acad Sci U S A. 2010;107:16325-30 pubmed 出版商
Xu Y, Gendron T, Zhang Y, Lin W, D Alton S, Sheng H, et al. Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice. J Neurosci. 2010;30:10851-9 pubmed 出版商
Ling S, Albuquerque C, Han J, Lagier Tourenne C, Tokunaga S, Zhou H, et al. ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS. Proc Natl Acad Sci U S A. 2010;107:13318-23 pubmed 出版商
Saito T, Hanai S, Takashima S, Nakagawa E, Okazaki S, Inoue T, et al. Neocortical layer formation of human developing brains and lissencephalies: consideration of layer-specific marker expression. Cereb Cortex. 2011;21:588-96 pubmed 出版商
Jansen C, Head M, van Gool W, Baas F, Yull H, Ironside J, et al. The first case of protease-sensitive prionopathy (PSPr) in The Netherlands: a patient with an unusual GSS-like clinical phenotype. J Neurol Neurosurg Psychiatry. 2010;81:1052-5 pubmed 出版商
Ash P, Zhang Y, Roberts C, Saldi T, Hutter H, Buratti E, et al. Neurotoxic effects of TDP-43 overexpression in C. elegans. Hum Mol Genet. 2010;19:3206-18 pubmed 出版商
Maruyama H, Morino H, Ito H, Izumi Y, Kato H, Watanabe Y, et al. Mutations of optineurin in amyotrophic lateral sclerosis. Nature. 2010;465:223-6 pubmed 出版商
Braak H, Ludolph A, Thal D, Del Tredici K. Amyotrophic lateral sclerosis: dash-like accumulation of phosphorylated TDP-43 in somatodendritic and axonal compartments of somatomotor neurons of the lower brainstem and spinal cord. Acta Neuropathol. 2010;120:67-74 pubmed 出版商
Ilieva E, Naudi A, Kichev A, Ferrer I, Pamplona R, Portero Otin M. Depletion of oxidative and endoplasmic reticulum stress regulators in Pick disease. Free Radic Biol Med. 2010;48:1302-10 pubmed 出版商
Wils H, Kleinberger G, Janssens J, Pereson S, Joris G, Cuijt I, et al. TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration. Proc Natl Acad Sci U S A. 2010;107:3858-63 pubmed 出版商
Zhang H, Tanji K, Yoshida H, Hayakari M, Shibata T, Mori F, et al. Alteration of biochemical and pathological properties of TDP-43 protein by a lipid mediator, 15-deoxy-Delta(12,14)-prostaglandin J(2). Exp Neurol. 2010;222:296-303 pubmed 出版商
Fiesel F, Voigt A, Weber S, Van den Haute C, Waldenmaier A, Görner K, et al. Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. EMBO J. 2010;29:209-21 pubmed 出版商
Nishimoto Y, Ito D, Yagi T, Nihei Y, Tsunoda Y, Suzuki N. Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43. J Biol Chem. 2010;285:608-19 pubmed 出版商
Foulds P, Davidson Y, Mishra M, Hobson D, Humphreys K, Taylor M, et al. Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration. Acta Neuropathol. 2009;118:647-58 pubmed 出版商
Velakoulis D, Walterfang M, Mocellin R, Pantelis C, Dean B, McLean C. Abnormal hippocampal distribution of TDP-43 in patients with-late onset psychosis. Aust N Z J Psychiatry. 2009;43:739-45 pubmed 出版商
Moisse K, Mepham J, Volkening K, Welch I, Hill T, Strong M. Cytosolic TDP-43 expression following axotomy is associated with caspase 3 activation in NFL-/- mice: support for a role for TDP-43 in the physiological response to neuronal injury. Brain Res. 2009;1296:176-86 pubmed 出版商
Velakoulis D, Walterfang M, Mocellin R, Pantelis C, McLean C. Frontotemporal dementia presenting as schizophrenia-like psychosis in young people: clinicopathological series and review of cases. Br J Psychiatry. 2009;194:298-305 pubmed 出版商
Humayun S, Gohar M, Volkening K, Moisse K, Leystra Lantz C, Mepham J, et al. The complement factor C5a receptor is upregulated in NFL-/- mouse motor neurons. J Neuroimmunol. 2009;210:52-62 pubmed 出版商
Gitcho M, Strider J, Carter D, Taylor Reinwald L, Forman M, Goate A, et al. VCP mutations causing frontotemporal lobar degeneration disrupt localization of TDP-43 and induce cell death. J Biol Chem. 2009;284:12384-98 pubmed 出版商
Olive M, Janué A, Moreno D, Gamez J, Torrejón Escribano B, Ferrer I. TAR DNA-Binding protein 43 accumulation in protein aggregate myopathies. J Neuropathol Exp Neurol. 2009;68:262-73 pubmed 出版商
Rollinson S, Rizzu P, Sikkink S, Baker M, Halliwell N, Snowden J, et al. Ubiquitin associated protein 1 is a risk factor for frontotemporal lobar degeneration. Neurobiol Aging. 2009;30:656-65 pubmed 出版商
Igaz L, Kwong L, Chen Plotkin A, Winton M, Unger T, Xu Y, et al. Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies. J Biol Chem. 2009;284:8516-24 pubmed 出版商
Clarimon J, Molina Porcel L, Gomez Isla T, Blesa R, Guardia Laguarta C, Gonzalez Neira A, et al. Early-onset familial lewy body dementia with extensive tauopathy: a clinical, genetic, and neuropathological study. J Neuropathol Exp Neurol. 2009;68:73-82 pubmed 出版商
Moisse K, Volkening K, Leystra Lantz C, Welch I, Hill T, Strong M. Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: implications for TDP-43 in the physiological response to neuronal injury. Brain Res. 2009;1249:202-11 pubmed 出版商
Schwab C, Arai T, Hasegawa M, Yu S, McGeer P. Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of Huntington disease. J Neuropathol Exp Neurol. 2008;67:1159-65 pubmed 出版商
Steinacker P, Hendrich C, Sperfeld A, Jesse S, von Arnim C, Lehnert S, et al. TDP-43 in cerebrospinal fluid of patients with frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Arch Neurol. 2008;65:1481-7 pubmed 出版商
Seppänen A, Pikkarainen M, Hartikainen P, Hofmann S, Majamaa K, Alafuzoff I. Expression of collagen XVII and ubiquitin-binding protein p62 in motor neuron disease. Brain Res. 2009;1247:171-7 pubmed 出版商
Kasai T, Tokuda T, Ishigami N, Sasayama H, Foulds P, Mitchell D, et al. Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Acta Neuropathol. 2009;117:55-62 pubmed 出版商
Nishihira Y, Tan C, Hoshi Y, Iwanaga K, Yamada M, Kawachi I, et al. Sporadic amyotrophic lateral sclerosis of long duration is associated with relatively mild TDP-43 pathology. Acta Neuropathol. 2009;117:45-53 pubmed 出版商
Skoglund L, Brundin R, Olofsson T, Kalimo H, Ingvast S, Blom E, et al. Frontotemporal dementia in a large Swedish family is caused by a progranulin null mutation. Neurogenetics. 2009;10:27-34 pubmed 出版商
Miklossy J, Steele J, Yu S, McCall S, Sandberg G, McGeer E, et al. Enduring involvement of tau, beta-amyloid, alpha-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonism-dementia complex of Guam (ALS/PDC). Acta Neuropathol. 2008;116:625-37 pubmed 出版商
Kovacs G, Majtenyi K, Spina S, Murrell J, Gelpi E, Hoftberger R, et al. White matter tauopathy with globular glial inclusions: a distinct sporadic frontotemporal lobar degeneration. J Neuropathol Exp Neurol. 2008;67:963-75 pubmed 出版商
Weihl C, Temiz P, Miller S, Watts G, Smith C, Forman M, et al. TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia. J Neurol Neurosurg Psychiatry. 2008;79:1186-9 pubmed 出版商
Lin W, Dickson D. Ultrastructural localization of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases. Acta Neuropathol. 2008;116:205-13 pubmed 出版商
Mori F, Tanji K, Zhang H, Nishihira Y, Tan C, Takahashi H, et al. Maturation process of TDP-43-positive neuronal cytoplasmic inclusions in amyotrophic lateral sclerosis with and without dementia. Acta Neuropathol. 2008;116:193-203 pubmed 出版商
Sleegers K, Kumar Singh S, Cruts M, Van Broeckhoven C. Molecular pathogenesis of frontotemporal lobar degeneration: basic science seminar in neurology. Arch Neurol. 2008;65:700-4 pubmed 出版商
Igaz L, Kwong L, Xu Y, Truax A, Uryu K, Neumann M, et al. Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Am J Pathol. 2008;173:182-94 pubmed 出版商
Foulds P, McAuley E, Gibbons L, Davidson Y, Pickering Brown S, Neary D, et al. TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration. Acta Neuropathol. 2008;116:141-6 pubmed 出版商
Johnson B, McCaffery J, Lindquist S, Gitler A. A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity. Proc Natl Acad Sci U S A. 2008;105:6439-44 pubmed 出版商
Winton M, Igaz L, Wong M, Kwong L, Trojanowski J, Lee V. Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation. J Biol Chem. 2008;283:13302-9 pubmed 出版商
Zhang H, Tanji K, Mori F, Wakabayashi K. Epitope mapping of 2E2-D3, a monoclonal antibody directed against human TDP-43. Neurosci Lett. 2008;434:170-4 pubmed 出版商
Beck J, Rohrer J, Campbell T, Isaacs A, Morrison K, Goodall E, et al. A distinct clinical, neuropsychological and radiological phenotype is associated with progranulin gene mutations in a large UK series. Brain. 2008;131:706-20 pubmed 出版商
Sanelli T, Xiao S, Horne P, Bilbao J, Zinman L, Robertson J. Evidence that TDP-43 is not the major ubiquitinated target within the pathological inclusions of amyotrophic lateral sclerosis. J Neuropathol Exp Neurol. 2007;66:1147-53 pubmed
Kovacs G, Pittman A, Revesz T, Luk C, Lees A, Kiss E, et al. MAPT S305I mutation: implications for argyrophilic grain disease. Acta Neuropathol. 2008;116:103-18 pubmed
Shankaran S, Capell A, Hruscha A, Fellerer K, Neumann M, Schmid B, et al. Missense mutations in the progranulin gene linked to frontotemporal lobar degeneration with ubiquitin-immunoreactive inclusions reduce progranulin production and secretion. J Biol Chem. 2008;283:1744-53 pubmed
Zhang H, Tan C, Mori F, Tanji K, Kakita A, Takahashi H, et al. TDP-43-immunoreactive neuronal and glial inclusions in the neostriatum in amyotrophic lateral sclerosis with and without dementia. Acta Neuropathol. 2008;115:115-22 pubmed
Amador Ortiz C, Lin W, Ahmed Z, Personett D, Davies P, Duara R, et al. TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease. Ann Neurol. 2007;61:435-45 pubmed
Mackenzie I, Bigio E, Ince P, Geser F, Neumann M, Cairns N, et al. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Ann Neurol. 2007;61:427-34 pubmed
Hasegawa M, Arai T, Akiyama H, Nonaka T, Mori H, Hashimoto T, et al. TDP-43 is deposited in the Guam parkinsonism-dementia complex brains. Brain. 2007;130:1386-94 pubmed
Neumann M, Kwong L, Truax A, Vanmassenhove B, Kretzschmar H, Van Deerlin V, et al. TDP-43-positive white matter pathology in frontotemporal lobar degeneration with ubiquitin-positive inclusions. J Neuropathol Exp Neurol. 2007;66:177-83 pubmed
Tan C, Eguchi H, Tagawa A, Onodera O, Iwasaki T, Tsujino A, et al. TDP-43 immunoreactivity in neuronal inclusions in familial amyotrophic lateral sclerosis with or without SOD1 gene mutation. Acta Neuropathol. 2007;113:535-42 pubmed
Neumann M, Mackenzie I, Cairns N, Boyer P, Markesbery W, Smith C, et al. TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations. J Neuropathol Exp Neurol. 2007;66:152-7 pubmed
Arai T, Hasegawa M, Akiyama H, Ikeda K, Nonaka T, Mori H, et al. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem Biophys Res Commun. 2006;351:602-11 pubmed
产品信息
品牌 :
Novus
master code :
H00023435-M01
SKU号 :
H00023435-M01
产品名称 :
TDP-43/TARDBP抗体(2E2-D3)
描述 :
The TDP-43/TARDBP Antibody (2E2-D3) from Novus Biologicals is a mouse monoclonal antibody to TDP-43/TARDBP. This antibody reacts with human, mouse, rat, bacteria, insect, monkey, firefly. The TDP-43/TARDBP Antibody (2E2-D3) has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Functional, RNA Inhibition, Sandwich ELISA.
靶标 :
TDP-43/TARDBP
类别 :
一抗
单位尺寸 :
0.1毫克
缓冲液 :
在1x PBS, pH值7.4
克隆性 :
单克隆
克隆 :
2E2-D3
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
MSEYIRVTEDENDEPIEIPSEDDGTVLLSTVTAQFPGAC
GLRYRNPVSQCMRGVRLVEGILHAPDAGWGNLVYVVNYP
KDNKRKMDETDASSAVKVKRAVQKTSDLIVLGLPWKTTE
QDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRFTEYE
TQVKVMSQRHMIDGRWCDCKLPNSKQSQDEPLRSRKVFV
GRCTEDMTEDELREFFSQYGDVMDVFIPKPFRAFAFVTF
ADDQIAQSLCGEDLIIKGISVHISNA
TARDBP (NP_031401.1, 1 a.a. ~ 260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
抗体亚型 :
IgG1 Kappa
纯度 :
IgG纯化
物种 :
Human, Mouse, Rat, Bacteria, Insect, Monkey, Firefly
特异性 :
TARDBP-焦油DNA结合蛋白
理论上的分子量 :
45 kDa
基因符号 :
TARDBP
catalog number base :
H00023435-M01
accessionNumbers :
Q13148
应用 :
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Functional, RNA Inhibition, Sandwich ELISA
2020美元 :
399
2021美元 :
399美元
别名 :
ALS10TAR DNA结合蛋白43, 焦油DNA结合蛋白, TDP43, TDP-43, TDP-43TAR DNA结合蛋白43
储存 :
分成小份儿保存在-20C或-80C。 避免冻融循环
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。