产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
毛细血管扩张性共济失调症突变蛋白抗体
目录 :
NB100-104
规格 :
0.05 ml (also 0.025 ml)
价格 :
399美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
异硫氰酸荧光素
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 25
出版应用/物种/样本/稀释参考文献
  • 免疫沉淀; 人类; 图 s3
  • 免疫细胞化学; 人类; 1:500; 图 5
  • 免疫印迹; 人类; 图 s3
Qi Y, Qiu Q, Gu X, Tian Y, Zhang Y. ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts. Sci Rep. 2016;6:24700 pubmed 出版商
Hashimoto T, Urushihara Y, Murata Y, Fujishima Y, Hosoi Y. AMPK increases expression of ATM through transcriptional factor Sp1 and induces radioresistance under severe hypoxia in glioblastoma cell lines. Biochem Biophys Res Commun. 2022;590:82-88 pubmed 出版商
Sato H, Singer R. Cellular variability of nonsense-mediated mRNA decay. Nat Commun. 2021;12:7203 pubmed 出版商
Nishiyama Y, Morita A, Tatsuta S, Kanamaru M, Sakaue M, Ueda K, et al. Isorhamnetin Promotes 53BP1 Recruitment through the Enhancement of ATM Phosphorylation and Protects Mice from Radiation Gastrointestinal Syndrome. Genes (Basel). 2021;12: pubmed 出版商
Chakraborty P, Hiom K. DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination. Nat Commun. 2021;12:4126 pubmed 出版商
Gupta M, Liu X, Teraoka S, Wright J, Gatti R, QUINLAN A, et al. Genes affecting ionizing radiation survival identified through combined exome sequencing and functional screening. Hum Mutat. 2021;42:1124-1138 pubmed 出版商
Zhang J, Saravanabavan S, Chandra A, Munt A, Wong A, Harris P, et al. Up-Regulation of DNA Damage Response Signaling in Autosomal Dominant Polycystic Kidney Disease. Am J Pathol. 2021;191:902-920 pubmed 出版商
Chakravarti D, Hu B, Mao X, Rashid A, Li J, Li J, et al. Telomere dysfunction activates YAP1 to drive tissue inflammation. Nat Commun. 2020;11:4766 pubmed 出版商
Habib R, Kim R, Neitzel H, Demuth I, Chrzanowska K, Seemanova E, et al. Telomere attrition and dysfunction: a potential trigger of the progeroid phenotype in nijmegen breakage syndrome. Aging (Albany NY). 2020;12:12342-12375 pubmed 出版商
Morita A, Aoshima K, Gulay K, Onishi S, Shibata Y, Yasui H, et al. High drug efflux pump capacity and low DNA damage response induce doxorubicin resistance in canine hemangiosarcoma cell lines. Res Vet Sci. 2019;127:1-10 pubmed 出版商
Pugliese G, Salaris F, Palermo V, Marabitti V, Morina N, Rosa A, et al. Inducible SMARCAL1 knockdown in iPSC reveals a link between replication stress and altered expression of master differentiation genes. Dis Model Mech. 2019;12: pubmed 出版商
Karki A, Putra J, Kim S, Laquaglia M, Perez Atayde A, Sadri Vakili G, et al. MDM4 expression in fibrolamellar hepatocellular carcinoma. Oncol Rep. 2019;42:1487-1496 pubmed 出版商
Yin Y, Xu L, Chang Y, Zeng T, Chen X, Wang A, et al. N-Myc promotes therapeutic resistance development of neuroendocrine prostate cancer by differentially regulating miR-421/ATM pathway. Mol Cancer. 2019;18:11 pubmed 出版商
Dworak N, Mąkosa D, Chatterjee M, Jividen K, Yang C, Snow C, et al. A nuclear lamina-chromatin-Ran GTPase axis modulates nuclear import and DNA damage signaling. Aging Cell. 2019;18:e12851 pubmed 出版商
Xu L, Ma E, Zeng T, Zhao R, Tao Y, Chen X, et al. ATM deficiency promotes progression of CRPC by enhancing Warburg effect. Endocr Relat Cancer. 2019;26:59-71 pubmed 出版商
Hashimoto T, Murata Y, Urushihara Y, Shiga S, Takeda K, Hosoi Y. Severe hypoxia increases expression of ATM and DNA-PKcs and it increases their activities through Src and AMPK signaling pathways. Biochem Biophys Res Commun. 2018;505:13-19 pubmed 出版商
Gu X, Qi Y, Feng Z, Ma L, Gao K, Zhang Y. Lead (Pb) induced ATM-dependent mitophagy via PINK1/Parkin pathway. Toxicol Lett. 2018;291:92-100 pubmed 出版商
Murata Y, Hashimoto T, Urushihara Y, Shiga S, Takeda K, Jingu K, et al. Knockdown of AMPKα decreases ATM expression and increases radiosensitivity under hypoxia and nutrient starvation in an SV40-transformed human fibroblast cell line, LM217. Biochem Biophys Res Commun. 2018;495:2566-2572 pubmed 出版商
Wang Z, He Y, Deng W, Lang L, Yang H, Jin B, et al. Atf3 deficiency promotes genome instability and spontaneous tumorigenesis in mice. Oncogene. 2018;37:18-27 pubmed 出版商
Wu P, Wang J, Chen C, Chao K, Chang M, Chen W, et al. Early Passage Mesenchymal Stem Cells Display Decreased Radiosensitivity and Increased DNA Repair Activity. Stem Cells Transl Med. 2017;6:1504-1514 pubmed 出版商
Li Z, Li J, Kong Y, Yan S, Ahmad N, Liu X. Plk1 Phosphorylation of Mre11 Antagonizes the DNA Damage Response. Cancer Res. 2017;77:3169-3180 pubmed 出版商
Frum R, Love I, Damle P, Mukhopadhyay N, Palit Deb S, Deb S, et al. Constitutive Activation of DNA Damage Checkpoint Signaling Contributes to Mutant p53 Accumulation via Modulation of p53 Ubiquitination. Mol Cancer Res. 2016;14:423-36 pubmed 出版商
Nagy Z, Kalousi A, Furst A, Koch M, Fischer B, Soutoglou E. Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs. PLoS Genet. 2016;12:e1005791 pubmed 出版商
Murata Y, Uehara Y, Hosoi Y. Activation of mTORC1 under nutrient starvation conditions increases cellular radiosensitivity in human liver cancer cell lines, HepG2 and HuH6. Biochem Biophys Res Commun. 2015;468:684-90 pubmed 出版商
Parplys A, Zhao W, Sharma N, Groesser T, Liang F, Maranon D, et al. NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability. Nucleic Acids Res. 2015;43:9817-34 pubmed 出版商
产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB100-104
SKU号 :
NB100-104
产品名称 :
毛细血管扩张性共济失调症突变蛋白抗体
描述 :
The ATM Antibody from Novus is a rabbit polyclonal antibody to ATM. This antibody reacts with human, mouse, rat, canine, kangaroo. The ATM Antibody has been validated for the following applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunoblotting.
靶标 :
毛细血管扩张性共济失调症突变蛋白
类别 :
一抗
单位尺寸 :
0.05 ml (also 0.025 ml)
缓冲液 :
PBS, 50% 甘油
克隆性 :
多克隆
浓度 :
2.5毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
ATM Antibody was made to a fragment of the human ATM protein corresponding to the C-terminus (within the last third of the protein sequence). [Uniprot: Q13315]
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
Human, Mouse, Rat, Canine, Kangaroo
理论上的分子量 :
351 kDa
基因符号 :
毛细血管扩张性共济失调症突变蛋白
accessionNumbers :
Q13315
应用 :
免疫印迹, 流式细胞仪, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学/免疫荧光, 免疫沉淀, 免疫组化石蜡, 免疫印迹
美元 :
399美元
别名 :
AT mutated, A-T mutated, AT1, ATA, ataxia telangiectasia mutated, ataxia telangiectasia mutated (includes complementation groups A, C and D), ATC, ATD, ATDC, ATE, ATM serine/threonine kinase, DKFZp781A0353, EC 2.7.11.1, MGC74674, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
储存 :
分成小份儿保存在-20C或-80C。 避免冻融循环
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。