出版应用/物种/样本/稀释 | 参考文献 |
---|
- 免疫印迹基因敲除验证; 人类; 1:1000; 图 s1b
- 免疫印迹; 人类; 1:1000; 图 s1b
| Zou X, Owusu M, Harris R, Jackson S, Loizou J, Nik Zainal S. Validating the concept of mutational signatures with isogenic cell models. Nat Commun. 2018;9:1744 pubmed 出版商
|
| Ding Y, Gui X, Chu X, Sun Y, Zhang S, Tong H, et al. MTH1 protects platelet mitochondria from oxidative damage and regulates platelet function and thrombosis. Nat Commun. 2023;14:4829 pubmed 出版商
|
| Henriksson S, Calder xf3 n Monta xf1 o J, Solvie D, Warpman Berglund U, Helleday T. Overexpressed c-Myc Sensitizes Cells to TH1579, a Mitotic Arrest and Oxidative DNA Damage Inducer. Biomolecules. 2022;12: pubmed 出版商
|
| Bialkowski K, Szpila A. Specific 8-oxo-dGTPase activity of MTH1 (NUDT1) protein as a quantitative marker and prognostic factor in human colorectal cancer. Free Radic Biol Med. 2021;176:257-264 pubmed 出版商
|
| Karsten S, Fiskesund R, Zhang X, Marttila P, Sanjiv K, Pham T, et al. MTH1 as a target to alleviate T cell driven diseases by selective suppression of activated T cells. Cell Death Differ. 2021;: pubmed 出版商
|
| Zhang L, Misiara L, Samaranayake G, Sharma N, Nguyen D, Tahara Y, et al. OGG1 co-inhibition antagonizes the tumor-inhibitory effects of targeting MTH1. Redox Biol. 2021;40:101848 pubmed 出版商
|
| Arczewska K, Krasuska W, Stachurska A, Karpińska K, Sikorska J, Kiedrowski M, et al. hMTH1 and GPX1 expression in human thyroid tissue is interrelated to prevent oxidative DNA damage. DNA Repair (Amst). 2020;95:102954 pubmed 出版商
|
| Okubo T, Patella P, D Alessandro I, Wilson R. A Neural Network for Wind-Guided Compass Navigation. Neuron. 2020;107:924-940.e18 pubmed 出版商
|
| Godoy P, Pour Khavari A, Rizzo M, Sakamoto Hojo E, Haghdoost S. Targeting NRF2, Regulator of Antioxidant System, to Sensitize Glioblastoma Neurosphere Cells to Radiation-Induced Oxidative Stress. Oxid Med Cell Longev. 2020;2020:2534643 pubmed 出版商
|
| McKellar C, Siwanowicz I, Dickson B, Simpson J. Controlling motor neurons of every muscle for fly proboscis reaching. elife. 2020;9: pubmed 出版商
|
| Städele C, Keles M, Mongeau J, Frye M. Non-canonical Receptive Field Properties and Neuromodulation of Feature-Detecting Neurons in Flies. Curr Biol. 2020;30:2508-2519.e6 pubmed 出版商
|
| Rudd S, Gad H, Sanjiv K, Amaral N, Hagenkort A, Groth P, et al. MTH1 inhibitor TH588 disturbs mitotic progression and induces mitosis-dependent accumulation of genomic 8-oxodG. Cancer Res. 2020;: pubmed 出版商
|
| Martin S, Smolders S, Van den Haute C, Heeman B, van Veen S, Crosiers D, et al. Mutated ATP10B increases Parkinson's disease risk by compromising lysosomal glucosylceramide export. Acta Neuropathol. 2020;139:1001-1024 pubmed 出版商
|
| Moukengue B, Brown H, Charrier C, Battaglia S, Baud huin M, Quillard T, et al. TH1579, MTH1 inhibitor, delays tumour growth and inhibits metastases development in osteosarcoma model. EBioMedicine. 2020;53:102704 pubmed 出版商
|
| Shiozaki H, Ohta K, Kazama H. A Multi-regional Network Encoding Heading and Steering Maneuvers in Drosophila. Neuron. 2020;106:126-141.e5 pubmed 出版商
|
| Tan G, Pryce B, Stabio A, Brigande J, Wang C, Xia Z, et al. Tgfβ signaling is critical for maintenance of the tendon cell fate. elife. 2020;9: pubmed 出版商
|
| Heath S, Christenson M, Oriol E, Saavedra Weisenhaus M, Kohn J, Behnia R. Circuit Mechanisms Underlying Chromatic Encoding in Drosophila Photoreceptors. Curr Biol. 2020;30:264-275.e8 pubmed 出版商
|
| Hernandez E, MacNamee S, Kaplan L, Lance K, Garcia Verdugo H, Farhadi D, et al. The astrocyte network in the ventral nerve cord neuropil of the Drosophila third-instar larva. J Comp Neurol. 2020;528:1683-1703 pubmed 出版商
|
| Bialkowski K, Kasprzak K. A profile of 8-oxo-dGTPase activities in the NCI-60 human cancer panel: Meta-analytic insight into the regulation and role of MTH1 (NUDT1) gene expression in carcinogenesis. Free Radic Biol Med. 2020;148:1-21 pubmed 出版商
|
| Fisher Y, Lu J, D Alessandro I, Wilson R. Sensorimotor experience remaps visual input to a heading-direction network. Nature. 2019;576:121-125 pubmed 出版商
|
| Yadav S, Bhagat S, Gupta A, Samaiya A, Srivastava A, Shukla S. Dietary-phytochemical mediated reversion of cancer-specific splicing inhibits Warburg effect in head and neck cancer. BMC Cancer. 2019;19:1031 pubmed 出版商
|
| Esteves P, Dard L, Brillac A, Hubert C, Sarlak S, Rousseau B, et al. Nuclear control of lung cancer cells migration, invasion and bioenergetics by eukaryotic translation initiation factor 3F. Oncogene. 2020;39:617-636 pubmed 出版商
|
| Wang J, Nagy N, Masucci M. The Epstein-Barr virus nuclear antigen-1 upregulates the cellular antioxidant defense to enable B-cell growth transformation and immortalization. Oncogene. 2020;39:603-616 pubmed 出版商
|
| McPherson L, Troccoli C, Ji D, Bowles A, Gardiner M, Mohsen M, et al. Increased MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue. DNA Repair (Amst). 2019;83:102644 pubmed 出版商
|
| Zhou W, Ma L, Yang J, Qiao H, Li L, Guo Q, et al. Potent and specific MTH1 inhibitors targeting gastric cancer. Cell Death Dis. 2019;10:434 pubmed 出版商
|
| Dolan M, Frechter S, Bates A, Dan C, Huoviala P, Roberts R, et al. Neurogenetic dissection of the Drosophila lateral horn reveals major outputs, diverse behavioural functions, and interactions with the mushroom body. elife. 2019;8: pubmed 出版商
|
| Losier T, Akuma M, McKee Muir O, LeBlond N, Suk Y, Alsaadi R, et al. AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles. Cell Rep. 2019;26:2150-2165.e5 pubmed 出版商
|
| Andrade I, Riebli N, Nguyen B, Omoto J, Cardona A, Hartenstein V. Developmentally Arrested Precursors of Pontine Neurons Establish an Embryonic Blueprint of the Drosophila Central Complex. Curr Biol. 2019;29:412-425.e3 pubmed 出版商
|
| McKellar C, Lillvis J, Bath D, Fitzgerald J, Cannon J, Simpson J, et al. Threshold-Based Ordering of Sequential Actions during Drosophila Courtship. Curr Biol. 2019;29:426-434.e6 pubmed 出版商
|
| Pompsch M, Vogel J, Classen F, Kranz P, Iliakis G, Riffkin H, et al. The presumed MTH1-inhibitor TH588 sensitizes colorectal carcinoma cells to ionizing radiation in hypoxia. BMC Cancer. 2018;18:1190 pubmed 出版商
|
| Cosmanescu F, Katsamba P, Sergeeva A, Ahlsen G, Patel S, Brewer J, et al. Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins. Neuron. 2018;100:1385-1400.e6 pubmed 出版商
|
| Barnhart E, Wang I, Wei H, Desplan C, Clandinin T. Sequential Nonlinear Filtering of Local Motion Cues by Global Motion Circuits. Neuron. 2018;100:229-243.e3 pubmed 出版商
|
| Chang Y, Tsao C, Sun Y. Temporal and spatial order of photoreceptor and glia projections into optic lobe in Drosophila. Sci Rep. 2018;8:12669 pubmed 出版商
|
| Wolff T, Rubin G. Neuroarchitecture of the Drosophila central complex: A catalog of nodulus and asymmetrical body neurons and a revision of the protocerebral bridge catalog. J Comp Neurol. 2018;526:2585-2611 pubmed 出版商
|
| Gupta A, Ajith A, Singh S, Panday R, Samaiya A, Shukla S. PAK2-c-Myc-PKM2 axis plays an essential role in head and neck oncogenesis via regulating Warburg effect. Cell Death Dis. 2018;9:825 pubmed 出版商
|
| Ribeiro I, Drews M, Bahl A, Machacek C, Borst A, Dickson B. Visual Projection Neurons Mediating Directed Courtship in Drosophila. Cell. 2018;174:607-621.e18 pubmed 出版商
|
| Konstantinides N, Kapuralin K, Fadil C, Barboza L, Satija R, Desplan C. Phenotypic Convergence: Distinct Transcription Factors Regulate Common Terminal Features. Cell. 2018;174:622-635.e13 pubmed 出版商
|
| Imaimatsu K, Fujii W, Hiramatsu R, Miura K, Kurohmaru M, Kanai Y. CRISPR/Cas9-mediated knock-in of the murine Y chromosomal Sry gene. J Reprod Dev. 2018;64:283-287 pubmed 出版商
|
| Xie T, Ho M, Liu Q, Horiuchi W, Lin C, Task D, et al. A Genetic Toolkit for Dissecting Dopamine Circuit Function in Drosophila. Cell Rep. 2018;23:652-665 pubmed 出版商
|
| Fan J, Zhao R, Parro C, Zhao W, Chou H, Robert J, et al. Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway. J Lipid Res. 2018;59:830-842 pubmed 出版商
|
| Saumweber T, Rohwedder A, Schleyer M, Eichler K, Chen Y, Aso Y, et al. Functional architecture of reward learning in mushroom body extrinsic neurons of larval Drosophila. Nat Commun. 2018;9:1104 pubmed 出版商
|
| Hashiguchi K, Hayashi M, Sekiguchi M, Umezu K. The roles of human MTH1, MTH2 and MTH3 proteins in maintaining genome stability under oxidative stress. Mutat Res. 2018;808:10-19 pubmed 出版商
|
| Page B, Valerie N, Wright R, Wallner O, Isaksson R, Carter M, et al. Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells. Nat Commun. 2018;9:250 pubmed 出版商
|
| Tocker A, Durocher E, Jacob K, Trieschman K, Talento S, Rechnitzer A, et al. The Scaffolding Protein IQGAP1 Interacts with NLRC3 and Inhibits Type I IFN Production. J Immunol. 2017;199:2896-2909 pubmed 出版商
|
| Yamamoto H, Umeda D, Matsumoto S, Kikuchi A. LDL switches the LRP6 internalization route from flotillin dependent to clathrin dependent in hepatic cells. J Cell Sci. 2017;130:3542-3556 pubmed 出版商
|
| Coleman S, Choi K, McGregor A. Cytomegalovirus UL128 homolog mutants that form a pentameric complex produce virus with impaired epithelial and trophoblast cell tropism and altered pathogenicity in the guinea pig. Virology. 2017;509:205-221 pubmed 出版商
|
| Hattori D, Aso Y, Swartz K, Rubin G, Abbott L, Axel R. Representations of Novelty and Familiarity in a Mushroom Body Compartment. Cell. 2017;169:956-969.e17 pubmed 出版商
|
| Wreden C, Meng J, Feng W, Chi W, Marshall Z, Heckscher E. Temporal Cohorts of Lineage-Related Neurons Perform Analogous Functions in Distinct Sensorimotor Circuits. Curr Biol. 2017;27:1521-1528.e4 pubmed 出版商
|
| Eshtad S, Mavajian Z, Rudd S, Visnes T, Bostrom J, Altun M, et al. hMYH and hMTH1 cooperate for survival in mismatch repair defective T-cell acute lymphoblastic leukemia. Oncogenesis. 2016;5:e275 pubmed 出版商
|
| Earley L, Powers J, Adachi K, Baumgart J, Meyer N, Xie Q, et al. Adeno-associated Virus (AAV) Assembly-Activating Protein Is Not an Essential Requirement for Capsid Assembly of AAV Serotypes 4, 5, and 11. J Virol. 2017;91: pubmed 出版商
|
| Zhou H, Jian Y, Leng Y, Liu N, Tian Y, Wang G, et al. Human MutT homologue 1 mRNA overexpression correlates to poor response of multiple myeloma. Int J Hematol. 2017;105:318-325 pubmed 出版商
|
| Shirangi T, Wong A, Truman J, Stern D. Doublesex Regulates the Connectivity of a Neural Circuit Controlling Drosophila Male Courtship Song. Dev Cell. 2016;37:533-44 pubmed 出版商
|
| Yokoi N, Fukata Y, Sekiya A, Murakami T, Kobayashi K, Fukata M. Identification of PSD-95 Depalmitoylating Enzymes. J Neurosci. 2016;36:6431-44 pubmed 出版商
|
| Zhou B, Ritt D, Morrison D, Der C, Cox A. Protein Kinase CK2? Maintains Extracellular Signal-regulated Kinase (ERK) Activity in a CK2? Kinase-independent Manner to Promote Resistance to Inhibitors of RAF and MEK but Not ERK in BRAF Mutant Melanoma. J Biol Chem. 2016;291:17804-15 pubmed 出版商
|
| Li N, Subrahmanyan L, Smith E, Yu X, Zaidi S, Choi M, et al. Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus. Am J Hum Genet. 2016;98:1082-1091 pubmed 出版商
|
| Lacin H, Truman J. Lineage mapping identifies molecular and architectural similarities between the larval and adult Drosophila central nervous system. elife. 2016;5:e13399 pubmed 出版商
|
| Ichinose T, Aso Y, Yamagata N, Abe A, Rubin G, Tanimoto H. Reward signal in a recurrent circuit drives appetitive long-term memory formation. elife. 2015;4:e10719 pubmed 出版商
|
| Huber K, Olek K, Müller A, Tan C, Bennett K, Colinge J, et al. Proteome-wide drug and metabolite interaction mapping by thermal-stability profiling. Nat Methods. 2015;12:1055-7 pubmed 出版商
|
| Hampel S, Franconville R, Simpson J, Seeds A. A neural command circuit for grooming movement control. elife. 2015;4:e08758 pubmed 出版商
|
| Carter M, Jemth A, Hagenkort A, Page B, Gustafsson R, Griese J, et al. Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2. Nat Commun. 2015;6:7871 pubmed 出版商
|
| Ohyama T, Schneider Mizell C, Fetter R, Aleman J, Franconville R, Rivera Alba M, et al. A multilevel multimodal circuit enhances action selection in Drosophila. Nature. 2015;520:633-9 pubmed 出版商
|
| Giribaldi M, Muñoz A, Halvorsen K, Patel A, Rai P. MTH1 expression is required for effective transformation by oncogenic HRAS. Oncotarget. 2015;6:11519-29 pubmed
|
| Bonora M, Wieckowsk M, Chinopoulos C, Kepp O, Kroemer G, Galluzzi L, et al. Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition. Oncogene. 2015;34:1608 pubmed 出版商
|
| Earley L, Kawano Y, Adachi K, Sun X, Dai M, Nakai H. Identification and characterization of nuclear and nucleolar localization signals in the adeno-associated virus serotype 2 assembly-activating protein. J Virol. 2015;89:3038-48 pubmed 出版商
|
| Rampal R, Alkalin A, Madzo J, Vasanthakumar A, Pronier E, Patel J, et al. DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia. Cell Rep. 2014;9:1841-55 pubmed 出版商
|
| Wolff T, Iyer N, Rubin G. Neuroarchitecture and neuroanatomy of the Drosophila central complex: A GAL4-based dissection of protocerebral bridge neurons and circuits. J Comp Neurol. 2015;523:997-1037 pubmed 出版商
|
| Oliverio S, Corazzari M, Sestito C, Piredda L, Ippolito G, Piacentini M. The spermidine analogue GC7 (N1-guanyl-1,7-diamineoheptane) induces autophagy through a mechanism not involving the hypusination of eIF5A. Amino Acids. 2014;46:2767-76 pubmed 出版商
|
| Patel A, Burton D, Halvorsen K, Balkan W, Reiner T, Perez Stable C, et al. MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways. Oncogene. 2015;34:2586-96 pubmed 出版商
|
| Jun L, Showalter A, Ali N, Dai F, Ma W, Coskun T, et al. A novel humanized GLP-1 receptor model enables both affinity purification and Cre-LoxP deletion of the receptor. PLoS ONE. 2014;9:e93746 pubmed 出版商
|
| Andreou M, Yan C, Skourides P. 40LoVe and Samba are involved in Xenopus neural development and functionally distinct from hnRNP AB. PLoS ONE. 2014;9:e85026 pubmed 出版商
|
| Ohkawa T, Fukata Y, Yamasaki M, Miyazaki T, Yokoi N, Takashima H, et al. Autoantibodies to epilepsy-related LGI1 in limbic encephalitis neutralize LGI1-ADAM22 interaction and reduce synaptic AMPA receptors. J Neurosci. 2013;33:18161-74 pubmed 出版商
|
| Nam G, Lee Y, Lee H, Ma M, Araki M, Araki K, et al. Interaction of CD99 with its paralog CD99L2 positively regulates CD99L2 trafficking to cell surfaces. J Immunol. 2013;191:5730-42 pubmed 出版商
|
| Gouttenoire E, Lupo V, Calpena E, Bartesaghi L, Schüpfer F, Medard J, et al. Sh3tc2 deficiency affects neuregulin-1/ErbB signaling. Glia. 2013;61:1041-51 pubmed 出版商
|
| Abdel Wahab O, Adli M, Lafave L, Gao J, Hricik T, Shih A, et al. ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression. Cancer Cell. 2012;22:180-93 pubmed 出版商
|
| Park Y, Park H. Differentiated embryo chondrocyte 1 (DEC1) represses PPAR?2 gene through interacting with CCAAT/enhancer binding protein ? (C/EBP?). Mol Cells. 2012;33:575-81 pubmed 出版商
|
| Kuver A, Shen H, Smith S. Regulation of the surface expression of ?4?2? GABAA receptors by high efficacy states. Brain Res. 2012;1463:1-20 pubmed 出版商
|
| Hubbi M, Luo W, Baek J, Semenza G. MCM proteins are negative regulators of hypoxia-inducible factor 1. Mol Cell. 2011;42:700-12 pubmed 出版商
|
| Idoyaga J, Cheong C, Suda K, Suda N, Kim J, Lee H, et al. Cutting edge: langerin/CD207 receptor on dendritic cells mediates efficient antigen presentation on MHC I and II products in vivo. J Immunol. 2008;180:3647-50 pubmed
|
| Park S, Cheong C, Idoyaga J, Kim J, Choi J, Do Y, et al. Generation and application of new rat monoclonal antibodies against synthetic FLAG and OLLAS tags for improved immunodetection. J Immunol Methods. 2008;331:27-38 pubmed
|