产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
ARNT/HIF-1乙抗体
目录 :
NB100-110
规格 :
0.1 ml (also 0.025 ml)
价格 :
449美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片, ChIP-Seq
更多信息或购买 :
文章摘录数: 40
出版应用/物种/样本/稀释参考文献
  • 染色质免疫沉淀 ; 人类; 图 1d, s2
Wang Y, Lyu Y, Tu K, Xu Q, Yang Y, Salman S, et al. Histone citrullination by PADI4 is required for HIF-dependent transcriptional responses to hypoxia and tumor vascularization. Sci Adv. 2021;7: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 3c
Chen J, Haller C, Jernigan F, Koerner S, Wong D, Wang Y, et al. Modulation of lymphocyte-mediated tissue repair by rational design of heterocyclic aryl hydrocarbon receptor agonists. Sci Adv. 2020;6:eaay8230 pubmed 出版商
  • ChIP-Seq; 人类; 图 1a
Platt J, Salama R, Smythies J, Choudhry H, Davies J, Hughes J, et al. Capture-C reveals preformed chromatin interactions between HIF-binding sites and distant promoters. EMBO Rep. 2016;17:1410-1421 pubmed
Naas S, Kr xfc ger R, Knaup K, Naas J, Grampp S, Schiffer M, et al. Hypoxia controls expression of kidney-pathogenic MUC1 variants. Life Sci Alliance. 2023;6: pubmed 出版商
Grampp S, Kr xfc ger R, Lauer V, Uebel S, Knaup K, Naas J, et al. Hypoxia hits APOL1 in the kidney. Kidney Int. 2023;104:53-60 pubmed 出版商
Lafleur V, Halim S, Choudhry H, Ratcliffe P, Mole D. Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma. Life Sci Alliance. 2023;6: pubmed 出版商
Yang Y, Chen C, Zuo Q, Lu H, Salman S, Lyu Y, et al. NARF is a hypoxia-induced coactivator for OCT4-mediated breast cancer stem cell specification. Sci Adv. 2022;8:eabo5000 pubmed 出版商
Salman S, Meyers D, Wicks E, Lee S, Datan E, Thomas A, et al. HIF inhibitor 32-134D eradicates murine hepatocellular carcinoma in combination with anti-PD1 therapy. J Clin Invest. 2022;132: pubmed 出版商
Protze J, Naas S, Kr xfc ger R, St xf6 hr C, Kraus A, Grampp S, et al. The renal cancer risk allele at 14q24.2 activates a novel hypoxia-inducible transcription factor-binding enhancer of DPF3 expression. J Biol Chem. 2022;298:101699 pubmed 出版商
Yang Y, Lu H, Chen C, Lyu Y, Cole R, Semenza G. HIF-1 Interacts with TRIM28 and DNA-PK to release paused RNA polymerase II and activate target gene transcription in response to hypoxia. Nat Commun. 2022;13:316 pubmed 出版商
Sasagawa T, Nagamatsu T, Yanagisawa M, Fujii T, Shibuya M. Hypoxia-inducible factor-1β is essential for upregulation of the hypoxia-induced FLT1 gene in placental trophoblasts. Mol Hum Reprod. 2021;27: pubmed 出版商
Wang J, Liu R, Wang Y, Mo H, Niu Y, Xu Q, et al. Repression of the miR-627-5p by histone deacetylase 3 contributes to hypoxia-induced hepatocellular carcinoma progression. J Cancer. 2021;12:5320-5330 pubmed 出版商
Zeng Z, Shi Z, Liu Y, Zhao J, Lu Q, Guo J, et al. HIF-1α-activated TM4SF1-AS1 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by enhancing TM4SF1 expression. Biochem Biophys Res Commun. 2021;566:80-86 pubmed 出版商
Wang R, Godet I, Yang Y, Salman S, Lu H, Lyu Y, et al. Hypoxia-inducible factor-dependent ADAM12 expression mediates breast cancer invasion and metastasis. Proc Natl Acad Sci U S A. 2021;118: pubmed 出版商
Seok S, Sun H, Kim Y, Kemper B, Kemper J. Defective FXR-SHP Regulation in Obesity Aberrantly Increases miR-802 Expression, Promoting Insulin Resistance and Fatty Liver. Diabetes. 2021;70:733-744 pubmed 出版商
Xin X, Kumar V, Lin F, Kumar V, Bhattarai R, Bhatt V, et al. Redox-responsive nanoplatform for codelivery of miR-519c and gemcitabine for pancreatic cancer therapy. Sci Adv. 2020;6: pubmed 出版商
Safi W, Kraus A, Grampp S, Schödel J, Buchholz B. Macrophage migration inhibitory factor is regulated by HIF-1α and cAMP and promotes renal cyst cell proliferation in a macrophage-independent manner. J Mol Med (Berl). 2020;98:1547-1559 pubmed 出版商
Ma X, Gao F, Chen Q, Xuan X, Wang Y, Deng H, et al. ACE2 modulates glucose homeostasis through GABA signaling during metabolic stress. J Endocrinol. 2020;246:223-236 pubmed 出版商
Ho J, Balukoff N, Theodoridis P, Wang M, Krieger J, Schatz J, et al. A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism. Nat Commun. 2020;11:2677 pubmed 出版商
Lu H, Xie Y, Tran L, Lan J, Yang Y, Murugan N, et al. Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness. J Clin Invest. 2020;: pubmed 出版商
Niu Y, Bao L, Chen Y, Wang C, Luo M, Zhang B, et al. HIF-2-induced long non-coding RNA RAB11B-AS1 promotes hypoxia-mediated angiogenesis and breast cancer metastasis. Cancer Res. 2020;: pubmed 出版商
Wierenga A, Cunningham A, Erdem A, Lopera N, Brouwers Vos A, Pruis M, et al. HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cells. Cancer Metab. 2019;7:11 pubmed 出版商
Orlando I, Lafleur V, Storti F, Spielmann P, Crowther L, Santambrogio S, et al. Distal and proximal hypoxia response elements cooperate to regulate organ-specific erythropoietin gene expression. Haematologica. 2019;: pubmed 出版商
Schmid V, Lafleur V, Lombardi O, Li R, Salama R, Colli L, et al. Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer. Sci Rep. 2019;9:18768 pubmed 出版商
Lauer V, Grampp S, PLATT J, Lafleur V, Lombardi O, Choudhry H, et al. Hypoxia drives glucose transporter 3 expression through HIF-mediated induction of the long non-coding RNA NICI. J Biol Chem. 2019;: pubmed 出版商
Osawa T, Shimamura T, Saito K, Hasegawa Y, Ishii N, Nishida M, et al. Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2. Cell Rep. 2019;29:89-103.e7 pubmed 出版商
Louphrasitthiphol P, Ledaki I, Chauhan J, Falletta P, Siddaway R, Buffa F, et al. MITF controls the TCA cycle to modulate the melanoma hypoxia response. Pigment Cell Melanoma Res. 2019;32:792-808 pubmed 出版商
Smythies J, Sun M, Masson N, Salama R, Simpson P, Murray E, et al. Inherent DNA-binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin. EMBO Rep. 2019;20: pubmed 出版商
Rahman M, Thomas P. Molecular cloning and characterization of two ARNT (ARNT-1 and ARNT-2) genes in Atlantic croaker and their expression during coexposure to hypoxia and PCB77. Environ Toxicol. 2019;34:160-171 pubmed 出版商
Rodrigues P, Patel S, Harewood L, Olan I, Vojtasova E, Syafruddin S, et al. NF-κB-Dependent Lymphoid Enhancer Co-option Promotes Renal Carcinoma Metastasis. Cancer Discov. 2018;8:850-865 pubmed 出版商
Kim Y, Seok S, Byun S, Kong B, Zhang Y, Guo G, et al. AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle. Nat Commun. 2018;9:540 pubmed 出版商
Tiana M, Acosta Iborra B, Puente Santamaría L, Hernansanz Agustín P, Worsley Hunt R, Masson N, et al. The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia. Nucleic Acids Res. 2017;: pubmed 出版商
Kobayashi M, Morinibu A, Koyasu S, Goto Y, Hiraoka M, Harada H. A circadian clock gene, PER2, activates HIF-1 as an effector molecule for recruitment of HIF-1α to promoter regions of its downstream genes. FEBS J. 2017;284:3804-3816 pubmed 出版商
Grampp S, Schmid V, Salama R, Lauer V, Kranz F, Platt J, et al. Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway. PLoS Genet. 2017;13:e1006872 pubmed 出版商
Grampp S, Platt J, Lauer V, Salama R, Kranz F, Neumann V, et al. Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer. Nat Commun. 2016;7:13183 pubmed 出版商
Kraus A, Grampp S, Goppelt Struebe M, Schreiber R, Kunzelmann K, Peters D, et al. P2Y2R is a direct target of HIF-1? and mediates secretion-dependent cyst growth of renal cyst-forming epithelial cells. Purinergic Signal. 2016;12:687-695 pubmed
Salama R, Masson N, Simpson P, Sciesielski L, Sun M, Tian Y, et al. Heterogeneous Effects of Direct Hypoxia Pathway Activation in Kidney Cancer. PLoS ONE. 2015;10:e0134645 pubmed 出版商
Long F, Si L, Long X, YANG B, Wang X, Zhang F. 2ME2 increase radiation-induced apoptosis of keloid fibroblasts by targeting HIF-1α in vitro. Australas J Dermatol. 2016;57:e32-8 pubmed 出版商
Wong W, Richardson T, Seykora J, Cotsarelis G, Simon M. Hypoxia-inducible factors regulate filaggrin expression and epidermal barrier function. J Invest Dermatol. 2015;135:454-461 pubmed 出版商
Rataj F, Möller F, Jähne M, Hönscheid P, Zierau O, Vollmer G, et al. Progesterone, as well as 17?-estradiol, is important for regulating AHR battery homoeostasis in the rat uterus. Arch Toxicol. 2015;89:393-404 pubmed 出版商
产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB100-110
SKU号 :
NB100-110
产品名称 :
ARNT/HIF-1乙抗体
描述 :
The ARNT/HIF-1 beta Antibody from Novus is a rabbit polyclonal antibody to ARNT/HIF-1 beta. This antibody reacts with human, mouse, rat, bovine, canine, fish, ferret, sheep. The ARNT/HIF-1 beta Antibody has been validated for the following applications: Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunoblotting, Gel Supershift Assay, Chromatin Immunoprecipitation (ChIP).
靶标 :
ARNT/HIF-1乙
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
Whole antisera
克隆性 :
多克隆
共轭标签 :
未共轭
宿主 :
免疫原 :
ARNT/HIF-1 beta Antibody was developed against a fusion protein to human HIF-1 beta containing amino acids 496-789. [UniProt# P27540]
抗体亚型 :
IgG
纯度 :
Unpurified
物种 :
人类, 小鼠, 大鼠, 牛, 狗, 鱼类, 白鼬, 羊
特异性 :
ARNT/HIF-1 beta Antibody is specific for HIF-1 beta/ARNT
理论上的分子量 :
86.6 kDa
基因符号 :
ARNT
accessionNumbers :
P27540
应用 :
Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunoblotting, Gel Supershift Assay, Chromatin Immunoprecipitation (ChIP)
美元 :
449美元
别名 :
ARNT, ARNT protein, aryl hydrocarbon receptor nuclear translocator, BHLHE2, Class E Basic Helix-Loop-Helix Protein 2, Dioxin Receptor, Nuclear Translocator, HIF-1 Beta, HIF1B, HIF-1beta, HIF-1-beta, HIF1-beta, HIF1BETA, hypoxia-inducible factor 1, beta subunit, Hypoxia-inducible factor 1-beta, TANGO
储存 :
分成小份儿保存在-20C或-80C。 避免冻融循环
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。