产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
HIF-2甲/EPAS1抗体
目录 :
NB100-122
规格 :
0.1 ml (also 0.025 ml)
价格 :
379美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
1B10
反应物种 :
African green monkey, 人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 305
出版应用/物种/样本/稀释参考文献
  • 染色质免疫沉淀 ; 人类; 图 1d, s2
  • 免疫印迹; 人类; 1:1000; 图 1a
Wang Y, Lyu Y, Tu K, Xu Q, Yang Y, Salman S, et al. Histone citrullination by PADI4 is required for HIF-dependent transcriptional responses to hypoxia and tumor vascularization. Sci Adv. 2021;7: pubmed 出版商
  • 免疫印迹; 小鼠; 图 3c
Geng G, Liu J, Xu C, Pei Y, Chen L, Mu C, et al. Receptor-mediated mitophagy regulates EPO production and protects against renal anemia. elife. 2021;10: pubmed 出版商
  • 免疫印迹; 小鼠; 图 1a, 5b
Lee Y, Riopel M, Cabrales P, Bandyopadhyay G. Hepatocyte-specific HIF-1α ablation improves obesity-induced glucose intolerance by reducing first-pass GLP-1 degradation. Sci Adv. 2019;5:eaaw4176 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 4c
Chang S, Mori D, Kobayashi H, Mori Y, Nakamoto H, Okada K, et al. Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway. Nat Commun. 2019;10:1442 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s4c
Halvarsson C, Rörby E, Eliasson P, Lang S, Soneji S, Jönsson J. Putative role of NF-kB but not HIF-1α in hypoxia-dependent regulation of oxidative stress in hematopoietic stem and progenitor cells. Antioxid Redox Signal. 2019;: pubmed 出版商
  • 免疫印迹; 小鼠; 1:100; 图 1j
Santana Codina N, Gableske S, Quiles Del Rey M, Małachowska B, Jedrychowski M, Biancur D, et al. NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms. Haematologica. 2019;: pubmed 出版商
  • 免疫印迹; 小鼠; 图 6c
Liu N, Luo J, Kuang D, Xu S, Duan Y, Xia Y, et al. Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression. J Clin Invest. 2019;129:631-646 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 2g
Schwartz A, Das N, Ramakrishnan S, Jain C, Jurkovic M, Wu J, et al. Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload. J Clin Invest. 2019;129:336-348 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 3b
Kim Y, Lee M, Gu H, Kim J, Jeong S, Yeo S, et al. HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice. Dis Model Mech. 2018;11: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 1d
Bäcker V, Cheung F, Siveke J, Fandrey J, Winning S. Knockdown of myeloid cell hypoxia-inducible factor-1? ameliorates the acute pathology in DSS-induced colitis. PLoS ONE. 2017;12:e0190074 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5c
He X, Zeng H, Chen S, Roman R, Aschner J, Didion S, et al. Endothelial specific SIRT3 deletion impairs glycolysis and angiogenesis and causes diastolic dysfunction. J Mol Cell Cardiol. 2017;112:104-113 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 表 s1
Yasui T, Uezono N, Nakashima H, Noguchi H, Matsuda T, Noda Andoh T, et al. Hypoxia Epigenetically Confers Astrocytic Differentiation Potential on Human Pluripotent Cell-Derived Neural Precursor Cells. Stem Cell Reports. 2017;8:1743-1756 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 6c
  • 免疫印迹; 小鼠; 图 6a
Kuan I, Liang K, Wang Y, Kuo T, Meir Y, Wu S, et al. EpEX/EpCAM and Oct4 or Klf4 alone are sufficient to generate induced pluripotent stem cells through STAT3 and HIF2α. Sci Rep. 2017;7:41852 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5b
Gardner P, Liyanage S, Cristante E, Sampson R, Dick A, Ali R, et al. Hypoxia inducible factors are dispensable for myeloid cell migration into the inflamed mouse eye. Sci Rep. 2017;7:40830 pubmed 出版商
  • 免疫印迹; 人类; 图 s2
Kozlova N, Wottawa M, Katschinski D, Kristiansen G, Kietzmann T. Hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) is a direct regulator of epidermal growth factor receptor (EGFR) signaling in breast cancer. Oncotarget. 2017;8:9885-9898 pubmed 出版商
  • 免疫印迹; 人类; 图 1e
Thompson J, Nguyen Q, Singh M, Pavesic M, Nesterenko I, Nelson L, et al. Rho-associated kinase 1 inhibition is synthetically lethal with von Hippel-Lindau deficiency in clear cell renal cell carcinoma. Oncogene. 2017;36:1080-1089 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4f
Chen W, Hill H, Christie A, Kim M, Holloman E, Pavía Jiménez A, et al. Targeting renal cell carcinoma with a HIF-2 antagonist. Nature. 2016;539:112-117 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Lee M, Huang H, Chang T, Huang H, Hsieh S, Chen Y, et al. Genome-wide analysis of HIF-2? chromatin binding sites under normoxia in human bronchial epithelial cells (BEAS-2B) suggests its diverse functions. Sci Rep. 2016;6:29311 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3a
Mandl M, Lieberum M, Depping R. A HIF-1α-driven feed-forward loop augments HIF signalling in Hep3B cells by upregulation of ARNT. Cell Death Dis. 2016;7:e2284 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
  • 免疫印迹; African green monkey; 图 3
Higashimura Y, Kitakaze T, Harada N, Inui H, Nakano Y, Yamaji R. pVHL-mediated degradation of HIF-2? regulates estrogen receptor ? expression in normoxic breast cancer cells. FEBS Lett. 2016;590:2690-9 pubmed 出版商
  • 免疫组化; 人类; 图 1B
  • 免疫印迹; 人类; 1:500; 图 1B
Maugeri G, D Amico A, Reitano R, Magro G, Cavallaro S, Salomone S, et al. PACAP and VIP Inhibit the Invasiveness of Glioblastoma Cells Exposed to Hypoxia through the Regulation of HIFs and EGFR Expression. Front Pharmacol. 2016;7:139 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100; 图 1a
Hoefflin R, Lahrmann B, Warsow G, Hübschmann D, Spath C, Walter B, et al. Spatial niche formation but not malignant progression is a driving force for intratumoural heterogeneity. Nat Commun. 2016;7:ncomms11845 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 1:150; 图 3b
Brooks D, Schwab L, Krutilina R, Parke D, Sethuraman A, Hoogewijs D, et al. ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models. Mol Cancer. 2016;15:26 pubmed 出版商
  • 免疫印迹; 人类; 图 3
German P, Bai S, Liu X, Sun M, Zhou L, Kalra S, et al. Phosphorylation-dependent cleavage regulates von Hippel Lindau proteostasis and function. Oncogene. 2016;35:4973-80 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 图 3
  • 免疫印迹; 人类; 图 3
Mori H, Yao Y, Learman B, Kurozumi K, Ishida J, Ramakrishnan S, et al. Induction of WNT11 by hypoxia and hypoxia-inducible factor-1α regulates cell proliferation, migration and invasion. Sci Rep. 2016;6:21520 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Heir P, Srikumar T, Bikopoulos G, Bunda S, Poon B, Lee J, et al. Oxygen-dependent Regulation of Erythropoietin Receptor Turnover and Signaling. J Biol Chem. 2016;291:7357-72 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4f
Nakazawa M, Eisinger Mathason T, Sadri N, Ochocki J, Gade T, Amin R, et al. Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth. Nat Commun. 2016;7:10539 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 10
  • 免疫沉淀; 人类; 图 1
  • 免疫印迹; 人类; 图 1
Luo W, Chen I, Chen Y, Alkam D, Wang Y, Semenza G. PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia. Oncotarget. 2016;7:6379-97 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 4d
  • 免疫印迹; 人类; 图 2a
Regan Anderson T, Ma S, Raj G, Cidlowski J, Helle T, Knutson T, et al. Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer. Cancer Res. 2016;76:1653-63 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s2
Kim Y, Nam H, Lee J, Park D, Kim C, Yu Y, et al. Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis. Nat Commun. 2016;7:10347 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 7
Chen K, Zeng J, Xiao H, Huang C, Hu J, Yao W, et al. Regulation of glucose metabolism by p62/SQSTM1 through HIF1α. J Cell Sci. 2016;129:817-30 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 4
  • 免疫印迹; 人类; 1:500; 图 3
Aquino Gálvez A, González Ávila G, Delgado Tello J, Castillejos López M, Mendoza Milla C, Zúñiga J, et al. Effects of 2-methoxyestradiol on apoptosis and HIF-1α and HIF-2α expression in lung cancer cells under normoxia and hypoxia. Oncol Rep. 2016;35:577-83 pubmed 出版商
  • 免疫沉淀; 人类; 1:2000; 图 2a
Taïeb D, Barlier A, Yang C, Pertuit M, Tchoghandjian A, Rochette C, et al. Somatic gain-of-function HIF2A mutations in sporadic central nervous system hemangioblastomas. J Neurooncol. 2016;126:473-81 pubmed 出版商
Sun H, Li Q, Song Z, Li C. Hypoxia induction of SH2D3A triggers malignant progression of lung cancer. Stem Cell Res. 2022;58:102630 pubmed 出版商
Zhao S, Zhou L, Dicker D, Lev A, Zhang S, Ross E, et al. Anti-cancer efficacy including Rb-deficient tumors and VHL-independent HIF1α proteasomal destabilization by dual targeting of CDK1 or CDK4/6 and HSP90. Sci Rep. 2021;11:20871 pubmed 出版商
Lim S, Kim Y, Park S, Choi J, Sung Y, Nishimori K, et al. mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia. elife. 2021;10: pubmed 出版商
Li X, Zhang X, Xia J, Zhang L, Chen B, Lian G, et al. Macrophage HIF-2α suppresses NLRP3 inflammasome activation and alleviates insulin resistance. Cell Rep. 2021;36:109607 pubmed 出版商
Caielli S, Cardenas J, de Jesus A, Baisch J, Walters L, Blanck J, et al. Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE. Cell. 2021;184:4464-4479.e19 pubmed 出版商
Firmino N, Cederberg R, Lee C, Shi R, Wadsworth B, Franks S, et al. Germinal center hypoxia in tumor-draining lymph nodes negatively regulates tumor-induced humoral immune responses in mouse models of breast cancer. Oncoimmunology. 2021;10:1959978 pubmed 出版商
Arnáiz E, Miar A, Bridges E, Prasad N, Hatch S, Ebner D, et al. Differential effects of HIF2α antagonist and HIF2α silencing in renal cancer and sensitivity to repurposed drugs. BMC Cancer. 2021;21:896 pubmed 出版商
Wang J, Liu R, Wang Y, Mo H, Niu Y, Xu Q, et al. Repression of the miR-627-5p by histone deacetylase 3 contributes to hypoxia-induced hepatocellular carcinoma progression. J Cancer. 2021;12:5320-5330 pubmed 出版商
DeBerge M, Lantz C, Dehn S, Sullivan D, van der Laan A, Niessen H, et al. Hypoxia-inducible factors individually facilitate inflammatory myeloid metabolism and inefficient cardiac repair. J Exp Med. 2021;218: pubmed 出版商
Zhang Z, Funcke J, Zi Z, Zhao S, Straub L, Zhu Y, et al. Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity. Cell Metab. 2021;33:1624-1639.e9 pubmed 出版商
Uba T, Matsuo Y, Sumi C, Shoji T, Nishi K, Kusunoki M, et al. Polysulfide inhibits hypoxia-elicited hypoxia-inducible factor activation in a mitochondria-dependent manner. Mitochondrion. 2021;59:255-266 pubmed 出版商
Mehibel M, Xu Y, Li C, Moon E, Thakkar K, Diep A, et al. Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination-deficient cancer models. J Clin Invest. 2021;131: pubmed 出版商
Zheng S, Ni J, Li Y, Lu M, Yao Y, Guo H, et al. 2-Methoxyestradiol synergizes with Erlotinib to suppress hepatocellular carcinoma by disrupting the PLAGL2-EGFR-HIF-1/2α signaling loop. Pharmacol Res. 2021;169:105685 pubmed 出版商
Wang R, Godet I, Yang Y, Salman S, Lu H, Lyu Y, et al. Hypoxia-inducible factor-dependent ADAM12 expression mediates breast cancer invasion and metastasis. Proc Natl Acad Sci U S A. 2021;118: pubmed 出版商
Hesse J, Groterath W, Owenier C, Steinhausen J, Ding Z, Steckel B, et al. Normoxic induction of HIF-1α by adenosine-A2B R signaling in epicardial stromal cells formed after myocardial infarction. FASEB J. 2021;35:e21517 pubmed 出版商
Skwarska A, Calder E, Sneddon D, Bolland H, Odyniec M, Mistry I, et al. Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor. Cell Chem Biol. 2021;: pubmed 出版商
Lee S, Park K, Lee G, Kim S, Song W, Kwon S, et al. Hypoxia-inducible factor-2α mediates senescence-associated intrinsic mechanisms of age-related bone loss. Exp Mol Med. 2021;53:591-604 pubmed 出版商
Ju C, Wang M, Tak E, Kim B, Emontzpohl C, Yang Y, et al. Hypoxia-inducible factor-1α-dependent induction of miR122 enhances hepatic ischemia tolerance. J Clin Invest. 2021;131: pubmed 出版商
Xie H, Song J, Godfrey J, Riscal R, Skuli N, Nissim I, et al. Glycogen metabolism is dispensable for tumour progression in clear cell renal cell carcinoma. Nat Metab. 2021;3:327-336 pubmed 出版商
Li P, Liu Y, Qin X, Chen K, Wang R, Yuan L, et al. SIRT1 attenuates renal fibrosis by repressing HIF-2α. Cell Death Discov. 2021;7:59 pubmed 出版商
Tanimura A, Nakazato A, Tanaka N. MYD88 signals induce tumour-initiating cell generation through the NF-κB-HIF-1α activation cascade. Sci Rep. 2021;11:3991 pubmed 出版商
Chen K, Zeng J, Sun Y, Ouyang W, Yu G, Zhou H, et al. Junction plakoglobin regulates and destabilizes HIF2α to inhibit tumorigenesis of renal cell carcinoma. Cancer Commun (Lond). 2021;41:316-332 pubmed 出版商
Dufies M, Verbiest A, Cooley L, Ndiaye P, He X, Nottet N, et al. Plk1, upregulated by HIF-2, mediates metastasis and drug resistance of clear cell renal cell carcinoma. Commun Biol. 2021;4:166 pubmed 出版商
Giacosa S, Pillet C, Séraudie I, Guyon L, Wallez Y, Roelants C, et al. Cooperative Blockade of CK2 and ATM Kinases Drives Apoptosis in VHL-Deficient Renal Carcinoma Cells through ROS Overproduction. Cancers (Basel). 2021;13: pubmed 出版商
Shao M, Hepler C, Zhang Q, Shan B, Vishvanath L, Henry G, et al. Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity. Cell Stem Cell. 2021;: pubmed 出版商
Kida N, Matsuo Y, Hashimoto Y, Nishi K, Tsuzuki Nakao T, Bono H, et al. Cigarette Smoke Extract Activates Hypoxia-Inducible Factors in a Reactive Oxygen Species-Dependent Manner in Stroma Cells from Human Endometrium. Antioxidants (Basel). 2021;10: pubmed 出版商
Ghosh M, Zhang D, Ollivierre H, Noguchi A, Springer D, LINEHAN W, et al. Therapeutic inhibition of HIF2α reverses polycythemia and pulmonary hypertension in murine models of two human diseases. Blood. 2020;: pubmed 出版商
Gkotinakou I, Kechagia E, Pazaitou Panayiotou K, Mylonis I, Liakos P, Tsakalof A. Calcitriol Suppresses HIF-1 and HIF-2 Transcriptional Activity by Reducing HIF-1/2α Protein Levels via a VDR-Independent Mechanism. Cells. 2020;9: pubmed 出版商
Han Q, Han F, Fan Y, Lian B, Xiao J, Sun W, et al. Notch3 is involved in the proliferation of renal cancer cells via regulation of cell cycle progression and HIF-2α. Oncol Lett. 2020;20:379 pubmed 出版商
Kleszka K, Leu T, Quinting T, Jastrow H, Pechlivanis S, Fandrey J, et al. Hypoxia-inducible factor-2α is crucial for proper brain development. Sci Rep. 2020;10:19146 pubmed 出版商
Romero Y, Castillejos López M, Romero Garcia S, Aguayo A, Herrera I, Garcia Martin M, et al. Antitumor Therapy under Hypoxic Microenvironment by the Combination of 2-Methoxyestradiol and Sodium Dichloroacetate on Human Non-Small-Cell Lung Cancer. Oxid Med Cell Longev. 2020;2020:3176375 pubmed 出版商
Kim H, Cho Y, Kim H, Kang D, Cheon D, Kim Y, et al. A system-level approach identifies HIF-2α as a critical regulator of chondrosarcoma progression. Nat Commun. 2020;11:5023 pubmed 出版商
Zhou Y, Ming J, Deng M, Li Y, Li B, Li J, et al. Chemically modified curcumin (CMC2.24) alleviates osteoarthritis progression by restoring cartilage homeostasis and inhibiting chondrocyte apoptosis via the NF-κB/HIF-2α axis. J Mol Med (Berl). 2020;98:1479-1491 pubmed 出版商
Samanta D, Huang T, Shah R, Yang Y, Pan F, Semenza G. BIRC2 Expression Impairs Anti-Cancer Immunity and Immunotherapy Efficacy. Cell Rep. 2020;32:108073 pubmed 出版商
Tiwari A, Tashiro K, Dixit A, Soni A, Vogel K, Hall B, et al. Loss of HIF1A From Pancreatic Cancer Cells Increases Expression of PPP1R1B and Degradation of p53 to Promote Invasion and Metastasis. Gastroenterology. 2020;159:1882-1897.e5 pubmed 出版商
Wang Y, Yang B, Lai Q, Shi J, Peng J, Zhang Y, et al. Reprogramming of m6A epitranscriptome is crucial for shaping of transcriptome and proteome in response to hypoxia. RNA Biol. 2020;:1-13 pubmed 出版商
Dowdell A, Cartwright I, Goldberg M, Kostelecky R, Ross T, Welch N, et al. The HIF target ATG9A is essential for epithelial barrier function and tight junction biogenesis. Mol Biol Cell. 2020;31:2249-2258 pubmed 出版商
Kogure A, Naito Y, Yamamoto Y, Yashiro M, Kiyono T, Yanagihara K, et al. Cancer cells with high-metastatic potential promote a glycolytic shift in activated fibroblasts. PLoS ONE. 2020;15:e0234613 pubmed 出版商
Riopel M, Moon J, Bandyopadhyay G, You S, Lam K, Liu X, et al. Inhibition of prolyl hydroxylases increases hepatic insulin and decreases glucagon sensitivity by an HIF-2α-dependent mechanism. Mol Metab. 2020;41:101039 pubmed 出版商
Wu Y, Cao Y, Liu H, Yao M, Ma N, Zhang B. Remodelin, an inhibitor of NAT10, could suppress hypoxia-induced or constitutional expression of HIFs in cells. Mol Cell Biochem. 2020;472:19-31 pubmed 出版商
Cohrs G, Drucks B, Synowitz M, Held Feindt J, Knerlich Lukoschus F. Expression Patterns of Hypoxia-Inducible Factors, Proinflammatory, and Neuroprotective Cytokines in Neuroepithelial Tissues of Lumbar Spinal Lipomas-A Pilot Study. World Neurosurg. 2020;141:e633-e644 pubmed 出版商
van Gisbergen M, Offermans K, Voets A, Lieuwes N, Biemans R, Hoffmann R, et al. Mitochondrial Dysfunction Inhibits Hypoxia-Induced HIF-1α Stabilization and Expression of Its Downstream Targets. Front Oncol. 2020;10:770 pubmed 出版商
Ho J, Balukoff N, Theodoridis P, Wang M, Krieger J, Schatz J, et al. A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism. Nat Commun. 2020;11:2677 pubmed 出版商
Lu H, Xie Y, Tran L, Lan J, Yang Y, Murugan N, et al. Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness. J Clin Invest. 2020;: pubmed 出版商
Park K, Han J, Kim S, Lim Y. Gamma-Aminobutyric Acid Increases Erythropoietin by Activation of Citrate Cycle and Stimulation of Hypoxia-Inducible Factors Expression in Rats. Biomolecules. 2020;10: pubmed 出版商
Shoda C, Miwa Y, Nimura K, Okamoto K, Yamagami S, Tsubota K, et al. Hypoxia-Inducible Factor Inhibitors Derived from Marine Products Suppress a Murine Model of Neovascular Retinopathy. Nutrients. 2020;12: pubmed 出版商
Acosta Iborra B, Tiana M, Maeso Alonso L, Hernández Sierra R, Herranz G, Santamaria A, et al. Hypoxia compensates cell cycle arrest with progenitor differentiation during angiogenesis. FASEB J. 2020;34:6654-6674 pubmed 出版商
Chen L, Wang Z, Xu Q, Liu Y, Chen L, Guo S, et al. The failure of DAC to induce OCT2 expression and its remission by hemoglobin-based nanocarriers under hypoxia in renal cell carcinoma. Theranostics. 2020;10:3562-3578 pubmed 出版商
Fabbri L, Dufies M, Lacas Gervais S, Gardie B, Gad Lapiteau S, Parola J, et al. Identification of a new aggressive axis driven by ciliogenesis and absence of VDAC1-ΔC in clear cell Renal Cell Carcinoma patients. Theranostics. 2020;10:2696-2713 pubmed 出版商
Park J, Kim M, Kim W, Kwon K, Ha K, Choi B, et al. Isolinderalactone suppresses human glioblastoma growth and angiogenic activity in 3D microfluidic chip and in vivo mouse models. Cancer Lett. 2020;478:71-81 pubmed 出版商
Sun X, Sun B, Babicheva A, Vanderpool R, Oita R, Casanova N, et al. Direct Extracellular NAMPT Involvement in Pulmonary Hypertension and Vascular Remodeling. Transcriptional Regulation by SOX and HIF-2α. Am J Respir Cell Mol Biol. 2020;63:92-103 pubmed 出版商
Gojkovic M, Darmasaputra G, Veliça P, Rundqvist H, Johnson R. Deregulated hypoxic response in myeloid cells: A model for high-altitude pulmonary oedema (HAPE). Acta Physiol (Oxf). 2020;229:e13461 pubmed 出版商
Sadaghianloo N, Contenti J, Dufies M, Parola J, Rouleau M, Lee S, et al. Co-culture of human fibroblasts, smooth muscle and endothelial cells promotes osteopontin induction in hypoxia. J Cell Mol Med. 2020;24:2931-2941 pubmed 出版商
Roelants C, Pillet C, Franquet Q, Sarrazin C, Peilleron N, Giacosa S, et al. Ex-Vivo Treatment of Tumor Tissue Slices as a Predictive Preclinical Method to Evaluate Targeted Therapies for Patients with Renal Carcinoma. Cancers (Basel). 2020;12: pubmed 出版商
Sivaraj K, Dharmalingam B, Mohanakrishnan V, Jeong H, Kato K, Schröder S, et al. YAP1 and TAZ negatively control bone angiogenesis by limiting hypoxia-inducible factor signaling in endothelial cells. elife. 2020;9: pubmed 出版商
Brown E, Rowan C, Strowitzki M, Fagundes R, Faber K, Güntsch A, et al. Mucosal inflammation downregulates PHD1 expression promoting a barrier-protective HIF-1α response in ulcerative colitis patients. FASEB J. 2020;34:3732-3742 pubmed 出版商
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产品信息
品牌 :
Novus
master code :
NB100-122
SKU号 :
NB100-122
产品名称 :
HIF-2甲/EPAS1抗体
描述 :
The HIF-2 alpha/EPAS1 Antibody from NB100-122 is a nb100-122 antibody to . This antibody reacts with angiogenesis, apoptosis, cancer, cancer stem cells, chromatin research, hif target genes, hypoxia, lipid and metabolism, transcription factors and regulators.
靶标 :
HIF-2甲/EPAS1
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
This HIF-2 alpha/EPAS1 Antibody was developed against a peptide derived from the C-terminus of mouse/human HIF-2 alpha protein.
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类, 小鼠, 大鼠, 鱼类, 仓鼠, 灵长类动物, 兔, 爬行类动物, 羊
特异性 :
This HIF-2 alpha/EPAS1 Antibody is specific for HIF-2 alpha/EPAS, and does not cross-react with HIF-1 alpha
理论上的分子量 :
96.5 kDa
基因符号 :
EPAS1
应用 :
Western Blot, Simple Western, Chromatin Immunoprecipitation, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, In vitro assay, Gel Super Shift Assays, SDS-Page, Knockout Validated, Knockdown Validated, Dual RNAscope ISH-IHC
美元 :
379美元
别名 :
anti hif 2 alpha, anti-HIF-2 alpha, Basic-helix-loop-helix-PAS protein MOP2, BHLHE73, Class E basic helix-loop-helix protein 73, ECYT4, endothelial PAS domain protein 1, endothelial PAS domain-containing protein 1, EPAS1, EPAS-1, HIF-1-alpha-like factor, HIF-1alpha-like factor, HIF-2 alpha, HIF2A, hif2a angiogenesis, HIF-2-alpha, HIF2-alpha, HLF, hypoxia-inducible factor 2 alpha, Hypoxia-inducible factor 2-alpha, Member of PAS protein 2, MOP2, PAS domain-containing protein 2, PASD2
储存 :
存放在-20°C
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。