ARNT/HIF-1 beta Antibody (H1beta234) - BSA Free | Novus Biologicals NB100-124 产品信息

产品简要

公司名称 :

Novus Biologicals

其他品牌 :

IMGENEX

产品类型 :

抗体

产品名称 :

ARNT/HIF-1 beta Antibody (H1beta234) - BSA Free

NB100-124

规格 :

0.1 ml (also 0.025 ml)

价格 :

449美元

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

AF488

克隆名称 :

H1beta234

反应物种 :

人类, 小鼠, 大鼠, 牛

应用 :

免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片, ChIP-Seq

更多信息或购买 :

Novus Biologicals 产品网页

文章摘录数: 100

出版应用/物种/样本/稀释	参考文献
免疫印迹; 人类; 图 5f	Murakami A, Wang L, Kalhorn S, Schraml P, Rathmell W, Tan A, et al. Context-dependent role for chromatin remodeling component PBRM1/BAF180 in clear cell renal cell carcinoma. Oncogenesis. 2017;6:e287 pubmed 出版商
ChIP-Seq; 小鼠; 图 s2b	Thienpont B, Steinbacher J, Zhao H, D Anna F, Kuchnio A, Ploumakis A, et al. Tumour hypoxia causes DNA hypermethylation by reducing TET activity. Nature. 2016;537:63-68 pubmed 出版商
染色质免疫沉淀 ; 人类; 图 10	Luo W, Chen I, Chen Y, Alkam D, Wang Y, Semenza G. PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia. Oncotarget. 2016;7:6379-97 pubmed 出版商
免疫印迹; 人类; 图 3	Altuntas S, Rossin F, Marsella C, D Eletto M, Diaz Hidalgo L, Farrace M, et al. The transglutaminase type 2 and pyruvate kinase isoenzyme M2 interplay in autophagy regulation. Oncotarget. 2015;6:44941-54 pubmed 出版商
染色质免疫沉淀 ; 人类免疫沉淀; 人类免疫印迹; 人类	Xiang L, Gilkes D, Hu H, Luo W, Bullen J, Liang H, et al. HIF-1Î± and TAZ serve as reciprocal co-activators in human breast cancer cells. Oncotarget. 2015;6:11768-78 pubmed
染色质免疫沉淀 ; 人类	Xiang L, Gilkes D, Hu H, Takano N, Luo W, Lu H, et al. Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype. Oncotarget. 2014;5:12509-27 pubmed
免疫印迹; 人类	Kim K, Kim D, Park J, Jung H, Cho Y, Kim H, et al. NNC 55-0396, a T-type Ca2+ channel inhibitor, inhibits angiogenesis via suppression of hypoxia-inducible factor-1α signal transduction. J Mol Med (Berl). 2015;93:499-509 pubmed 出版商
免疫组化-石蜡切片; 人类免疫细胞化学; 人类免疫印迹; 人类	Su E, Xin H, Yin P, Dyson M, Coon J, Farrow K, et al. Impaired fetoplacental angiogenesis in growth-restricted fetuses with abnormal umbilical artery doppler velocimetry is mediated by aryl hydrocarbon receptor nuclear translocator (ARNT). J Clin Endocrinol Metab. 2015;100:E30-40 pubmed 出版商
染色质免疫沉淀 ; 人类	Hu H, Takano N, Xiang L, Gilkes D, Luo W, Semenza G. Hypoxia-inducible factors enhance glutamate signaling in cancer cells. Oncotarget. 2014;5:8853-68 pubmed
免疫印迹; 大鼠	Peng Y, Yuan G, Khan S, Nanduri J, Makarenko V, Reddy V, et al. Regulation of hypoxia-inducible factor-? isoforms and redox state by carotid body neural activity in rats. J Physiol. 2014;592:3841-58 pubmed 出版商
染色质免疫沉淀 ; 人类	Wang T, Gilkes D, Takano N, Xiang L, Luo W, Bishop C, et al. Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis. Proc Natl Acad Sci U S A. 2014;111:E3234-42 pubmed 出版商
染色质免疫沉淀 ; 人类	Chaturvedi P, Gilkes D, Takano N, Semenza G. Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment. Proc Natl Acad Sci U S A. 2014;111:E2120-9 pubmed 出版商
免疫印迹; 人类	Zhang J, Ma W. Nerve growth factor regulates the expression of vascular endothelial growth factor in human HaCaT keratinocytes via PI3K/mTOR pathway. Genet Mol Res. 2014;13:9324-35 pubmed 出版商
免疫印迹; 人类	Sena J, Wang L, Pawlus M, Hu C. HIFs enhance the transcriptional activation and splicing of adrenomedullin. Mol Cancer Res. 2014;12:728-41 pubmed 出版商
免疫印迹; 人类	Suzuki K, Nishi K, Takabuchi S, Kai S, Matsuyama T, Kurosawa S, et al. Differential roles of prostaglandin E-type receptors in activation of hypoxia-inducible factor 1 by prostaglandin E1 in vascular-derived cells under non-hypoxic conditions. Peerj. 2013;1:e220 pubmed 出版商
染色质免疫沉淀 ; 大鼠染色质免疫沉淀 ; 人类	Takano N, Peng Y, Kumar G, Luo W, Hu H, Shimoda L, et al. Hypoxia-inducible factors regulate human and rat cystathionine ?-synthase gene expression. Biochem J. 2014;458:203-11 pubmed 出版商
染色质免疫沉淀 ; 人类	Gilkes D, Xiang L, Lee S, Chaturvedi P, Hubbi M, Wirtz D, et al. Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells. Proc Natl Acad Sci U S A. 2014;111:E384-93 pubmed 出版商
免疫印迹; 人类	Xiang L, Gilkes D, Chaturvedi P, Luo W, Hu H, Takano N, et al. Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer. J Mol Med (Berl). 2014;92:151-64 pubmed 出版商
染色质免疫沉淀 ; 小鼠免疫印迹; 小鼠	Cai Z, Luo W, Zhan H, Semenza G. Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart. Proc Natl Acad Sci U S A. 2013;110:17462-7 pubmed 出版商
染色质免疫沉淀 ; 人类免疫印迹; 人类	Sena J, Wang L, Hu C. BRG1 and BRM chromatin-remodeling complexes regulate the hypoxia response by acting as coactivators for a subset of hypoxia-inducible transcription factor target genes. Mol Cell Biol. 2013;33:3849-63 pubmed 出版商
免疫印迹; 人类	Yuan G, Peng Y, Reddy V, Makarenko V, Nanduri J, Khan S, et al. Mutual antagonism between hypoxia-inducible factors 1? and 2? regulates oxygen sensing and cardio-respiratory homeostasis. Proc Natl Acad Sci U S A. 2013;110:E1788-96 pubmed 出版商
免疫印迹; 人类	Pawlus M, Wang L, Hu C. STAT3 and HIF1? cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cells. Oncogene. 2014;33:1670-9 pubmed 出版商
免疫印迹; 小鼠	Balamurugan K, Sharan S, Klarmann K, Zhang Y, Coppola V, Summers G, et al. FBXW7Î± attenuates inflammatory signalling by downregulating C/EBPÎ´ and its target gene Tlr4. Nat Commun. 2013;4:1662 pubmed 出版商
免疫印迹; 人类	Storti P, Bolzoni M, Donofrio G, Airoldi I, Guasco D, Toscani D, et al. Hypoxia-inducible factor (HIF)-1? suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction. Leukemia. 2013;27:1697-706 pubmed 出版商
染色质免疫沉淀 ; 人类	Chaturvedi P, Gilkes D, Wong C, Luo W, Zhang H, Wei H, et al. Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis. J Clin Invest. 2013;123:189-205 pubmed 出版商
染色质免疫沉淀 ; 人类	Luo W, Chang R, Zhong J, Pandey A, Semenza G. Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression. Proc Natl Acad Sci U S A. 2012;109:E3367-76 pubmed 出版商
免疫印迹; 人类	Pawlus M, Wang L, Ware K, Hu C. Upstream stimulatory factor 2 and hypoxia-inducible factor 2? (HIF2?) cooperatively activate HIF2 target genes during hypoxia. Mol Cell Biol. 2012;32:4595-610 pubmed 出版商
免疫印迹; 人类	Krishnamachary B, Penet M, Nimmagadda S, Mironchik Y, Raman V, Solaiyappan M, et al. Hypoxia regulates CD44 and its variant isoforms through HIF-1? in triple negative breast cancer. PLoS ONE. 2012;7:e44078 pubmed 出版商
免疫沉淀; 人类免疫印迹; 人类	Chiabrando D, Fiorito V, Marro S, Silengo L, Altruda F, Tolosano E. Cell-specific regulation of Ferroportin transcription following experimentally-induced acute anemia in mice. Blood Cells Mol Dis. 2013;50:25-30 pubmed 出版商
免疫印迹; 小鼠	Zhang D, Li J, Zhang M, Gao G, Zuo Z, Yu Y, et al. The requirement of c-Jun N-terminal kinase 2 in regulation of hypoxia-inducing factor-1? mRNA stability. J Biol Chem. 2012;287:34361-71 pubmed 出版商
免疫印迹; 小鼠	Singh A, Mukhopadhyay C, Biswas S, Singh V, Mukhopadhyay C. Intracellular pathogen Leishmania donovani activates hypoxia inducible factor-1 by dual mechanism for survival advantage within macrophage. PLoS ONE. 2012;7:e38489 pubmed 出版商
免疫印迹; 人类	Uniacke J, Holterman C, Lachance G, Franovic A, Jacob M, Fabian M, et al. An oxygen-regulated switch in the protein synthesis machinery. Nature. 2012;486:126-9 pubmed 出版商
免疫组化; 人类	Kaira K, Nakagawa K, Ohde Y, Okumura T, Takahashi T, Murakami H, et al. Depolarized MUC1 expression is closely associated with hypoxic markers and poor outcome in resected non-small cell lung cancer. Int J Surg Pathol. 2012;20:223-32 pubmed 出版商
免疫印迹; 人类	Zhou L, Yang H. The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR. PLoS ONE. 2011;6:e23936 pubmed 出版商
免疫印迹; 人类	Wong C, Gilkes D, Zhang H, Chen J, Wei H, Chaturvedi P, et al. Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation. Proc Natl Acad Sci U S A. 2011;108:16369-74 pubmed 出版商
染色质免疫沉淀 ; 人类	Luo W, Hu H, Chang R, Zhong J, Knabel M, O Meally R, et al. Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1. Cell. 2011;145:732-44 pubmed 出版商
免疫印迹; 人类	Lin Q, Cong X, Yun Z. Differential hypoxic regulation of hypoxia-inducible factors 1alpha and 2alpha. Mol Cancer Res. 2011;9:757-65 pubmed 出版商
免疫组化; 人类免疫印迹; 人类	Tamama K, Kawasaki H, Kerpedjieva S, Guan J, Ganju R, Sen C. Differential roles of hypoxia inducible factor subunits in multipotential stromal cells under hypoxic condition. J Cell Biochem. 2011;112:804-17 pubmed 出版商
免疫印迹; 小鼠	Peng Y, Nanduri J, Khan S, Yuan G, Wang N, Kinsman B, et al. Hypoxia-inducible factor 2? (HIF-2?) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension. Proc Natl Acad Sci U S A. 2011;108:3065-70 pubmed 出版商
免疫印迹; 人类免疫印迹; 大鼠	Lunde I, Anton S, Bruusgaard J, Rana Z, Ellefsen S, Gundersen K. Hypoxia inducible factor 1 links fast-patterned muscle activity and fast muscle phenotype in rats. J Physiol. 2011;589:1443-54 pubmed 出版商
免疫印迹; 人类	Amir S, Wang R, Simons J, Mabjeesh N. SEPT9_v1 up-regulates hypoxia-inducible factor 1 by preventing its RACK1-mediated degradation. J Biol Chem. 2009;284:11142-51 pubmed 出版商
免疫组化-石蜡切片; 大鼠	Kransler K, McGarrigle B, Swartz D, Olson J. Lung development in the Holtzman rat is adversely affected by gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Sci. 2009;107:498-511 pubmed 出版商
免疫印迹; 小鼠	Aminova L, Siddiq A, Ratan R. Antioxidants, HIF prolyl hydroxylase inhibitors or short interfering RNAs to BNIP3 or PUMA, can prevent prodeath effects of the transcriptional activator, HIF-1alpha, in a mouse hippocampal neuronal line. Antioxid Redox Signal. 2008;10:1989-98 pubmed 出版商
免疫印迹; 人类	Puppo M, Battaglia F, Ottaviano C, Delfino S, Ribatti D, Varesio L, et al. Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha. Mol Cancer Ther. 2008;7:1974-84 pubmed 出版商
免疫印迹; 人类	Lauzier M, Robitaille G, Chan D, Giaccia A, Richard D. (2R)-[(4-Biphenylylsulfonyl)amino]-N-hydroxy-3-phenylpropionamide (BiPS), a matrix metalloprotease inhibitor, is a novel and potent activator of hypoxia-inducible factors. Mol Pharmacol. 2008;74:282-8 pubmed 出版商
免疫沉淀; 人类免疫印迹; 人类	Baek J, Liu Y, McDonald K, Wesley J, Zhang H, Semenza G. Spermidine/spermine N(1)-acetyltransferase-1 binds to hypoxia-inducible factor-1alpha (HIF-1alpha) and RACK1 and promotes ubiquitination and degradation of HIF-1alpha. J Biol Chem. 2007;282:33358-66 pubmed
免疫沉淀; 人类免疫印迹; 人类	Baek J, Liu Y, McDonald K, Wesley J, Hubbi M, Byun H, et al. Spermidine/spermine-N1-acetyltransferase 2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha. J Biol Chem. 2007;282:23572-80 pubmed
免疫印迹; 人类	Zhang H, Gao P, Fukuda R, Kumar G, Krishnamachary B, Zeller K, et al. HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell. 2007;11:407-20 pubmed
免疫印迹; 大鼠	Shimojo N, Jesmin S, Zaedi S, Otsuki T, Maeda S, Yamaguchi N, et al. Contributory role of VEGF overexpression in endothelin-1-induced cardiomyocyte hypertrophy. Am J Physiol Heart Circ Physiol. 2007;293:H474-81 pubmed
免疫印迹; 人类	Asikainen T, Chang L, Coalson J, Schneider B, Waleh N, Ikegami M, et al. Improved lung growth and function through hypoxia-inducible factor in primate chronic lung disease of prematurity. FASEB J. 2006;20:1698-700 pubmed
免疫印迹; 人类	Slomiany M, Rosenzweig S. Hypoxia-inducible factor-1-dependent and -independent regulation of insulin-like growth factor-1-stimulated vascular endothelial growth factor secretion. J Pharmacol Exp Ther. 2006;318:666-75 pubmed
免疫沉淀; 人类免疫印迹; 人类	Nakamura K, Martin K, Jackson J, Beppu K, Woo C, Thiele C. Brain-derived neurotrophic factor activation of TrkB induces vascular endothelial growth factor expression via hypoxia-inducible factor-1alpha in neuroblastoma cells. Cancer Res. 2006;66:4249-55 pubmed
免疫印迹; 人类	Hu C, Iyer S, Sataur A, Covello K, Chodosh L, Simon M. Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells. Mol Cell Biol. 2006;26:3514-26 pubmed
免疫印迹; 人类	Okuyama H, Krishnamachary B, Zhou Y, Nagasawa H, Bosch Marce M, Semenza G. Expression of vascular endothelial growth factor receptor 1 in bone marrow-derived mesenchymal cells is dependent on hypoxia-inducible factor 1. J Biol Chem. 2006;281:15554-63 pubmed
免疫印迹; 大鼠	Hui A, Bauer A, Striet J, Schnell P, Czyzyk Krzeska M. Calcium signaling stimulates translation of HIF-alpha during hypoxia. FASEB J. 2006;20:466-75 pubmed
免疫印迹; 人类	Amir S, Wang R, Matzkin H, Simons J, Mabjeesh N. MSF-A interacts with hypoxia-inducible factor-1alpha and augments hypoxia-inducible factor transcriptional activation to affect tumorigenicity and angiogenesis. Cancer Res. 2006;66:856-66 pubmed
免疫印迹; 人类	Schultz K, Fanburg B, Beasley D. Hypoxia and hypoxia-inducible factor-1alpha promote growth factor-induced proliferation of human vascular smooth muscle cells. Am J Physiol Heart Circ Physiol. 2006;290:H2528-34 pubmed
免疫印迹; 人类	Hirota K, Fukuda R, Takabuchi S, Kizaka Kondoh S, Adachi T, Fukuda K, et al. Induction of hypoxia-inducible factor 1 activity by muscarinic acetylcholine receptor signaling. J Biol Chem. 2004;279:41521-8 pubmed
免疫印迹; 人类	Slomiany M, Rosenzweig S. IGF-1-induced VEGF and IGFBP-3 secretion correlates with increased HIF-1 alpha expression and activity in retinal pigment epithelial cell line D407. Invest Ophthalmol Vis Sci. 2004;45:2838-47 pubmed
免疫印迹; 小鼠	Arsham A, Plas D, Thompson C, Simon M. Akt and hypoxia-inducible factor-1 independently enhance tumor growth and angiogenesis. Cancer Res. 2004;64:3500-7 pubmed
免疫印迹; 人类	Slomiany M, Rosenzweig S. Autocrine effects of IGF-I-induced VEGF and IGFBP-3 secretion in retinal pigment epithelial cell line ARPE-19. Am J Physiol Cell Physiol. 2004;287:C746-53 pubmed
免疫印迹; 人类	Tissot van Patot M, Bendrick Peart J, Beckey V, Serkova N, Zwerdlinger L. Greater vascularity, lowered HIF-1/DNA binding, and elevated GSH as markers of adaptation to in vivo chronic hypoxia. Am J Physiol Lung Cell Mol Physiol. 2004;287:L525-32 pubmed
免疫印迹; 人类	Rapisarda A, Uranchimeg B, Sordet O, Pommier Y, Shoemaker R, Melillo G. Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications. Cancer Res. 2004;64:1475-82 pubmed
免疫印迹; 人类	Alam H, Maizels E, Park Y, Ghaey S, Feiger Z, Chandel N, et al. Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is necessary for induction of select protein markers of f. J Biol Chem. 2004;279:19431-40 pubmed
免疫印迹; 人类	Fukuda R, Kelly B, Semenza G. Vascular endothelial growth factor gene expression in colon cancer cells exposed to prostaglandin E2 is mediated by hypoxia-inducible factor 1. Cancer Res. 2003;63:2330-4 pubmed
免疫印迹; 人类	Mabjeesh N, Escuin D, LaVallee T, Pribluda V, Swartz G, Johnson M, et al. 2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF. Cancer Cell. 2003;3:363-75 pubmed
免疫印迹; 人类	Mabjeesh N, Willard M, Harris W, Sun H, Wang R, Zhong H, et al. Dibenzoylmethane, a natural dietary compound, induces HIF-1 alpha and increases expression of VEGF. Biochem Biophys Res Commun. 2003;303:279-86 pubmed
免疫组化; 人类	Volm M, Koomagi R, Mattern J, Efferth T. Protein expression profiles indicative for drug resistance of non-small cell lung cancer. Br J Cancer. 2002;87:251-7 pubmed
免疫印迹; 人类	Rapisarda A, Uranchimeg B, Scudiero D, Selby M, Sausville E, Shoemaker R, et al. Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway. Cancer Res. 2002;62:4316-24 pubmed
免疫印迹; 人类	Fukuda R, Hirota K, Fan F, Jung Y, Ellis L, Semenza G. Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells. J Biol Chem. 2002;277:38205-11 pubmed
免疫印迹; 大鼠	Bernaudin M, Tang Y, Reilly M, Petit E, Sharp F. Brain genomic response following hypoxia and re-oxygenation in the neonatal rat. Identification of genes that might contribute to hypoxia-induced ischemic tolerance. J Biol Chem. 2002;277:39728-38 pubmed
免疫印迹; 人类	Mabjeesh N, Post D, Willard M, Kaur B, Van Meir E, Simons J, et al. Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells. Cancer Res. 2002;62:2478-82 pubmed
免疫印迹; 人类	Zhong H, Hanrahan C, van der Poel H, Simons J. Hypoxia-inducible factor 1alpha and 1beta proteins share common signaling pathways in human prostate cancer cells. Biochem Biophys Res Commun. 2001;284:352-6 pubmed
免疫组化; 人类免疫印迹; 人类	Zagzag D, Zhong H, Scalzitti J, Laughner E, Simons J, Semenza G. Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression. Cancer. 2000;88:2606-18 pubmed
	Tang J, Wu Z, Wang X, Hou Y, Bai Y, Tian Y. Hypoxia-Regulated lncRNA USP2-AS1 Drives Head and Neck Squamous Cell Carcinoma Progression. Cells. 2022;11: pubmed 出版商
	Chen Y, Cattoglio C, Dailey G, Zhu Q, Tjian R, Darzacq X. Mechanisms governing target search and binding dynamics of hypoxia-inducible factors. elife. 2022;11: pubmed 出版商
	Simmler P, Cortijo C, Koch L, Galliker P, Angori S, Bolck H, et al. SF3B1 facilitates HIF1-signaling and promotes malignancy in pancreatic cancer. Cell Rep. 2022;40:111266 pubmed 出版商
	Sasagawa T, Nagamatsu T, Yanagisawa M, Fujii T, Shibuya M. Hypoxia-inducible factor-1β is essential for upregulation of the hypoxia-induced FLT1 gene in placental trophoblasts. Mol Hum Reprod. 2021;27: pubmed 出版商
	Mehibel M, Xu Y, Li C, Moon E, Thakkar K, Diep A, et al. Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination-deficient cancer models. J Clin Invest. 2021;131: pubmed 出版商
	Samanta D, Huang T, Shah R, Yang Y, Pan F, Semenza G. BIRC2 Expression Impairs Anti-Cancer Immunity and Immunotherapy Efficacy. Cell Rep. 2020;32:108073 pubmed 出版商
	Tiwari A, Tashiro K, Dixit A, Soni A, Vogel K, Hall B, et al. Loss of HIF1A From Pancreatic Cancer Cells Increases Expression of PPP1R1B and Degradation of p53 to Promote Invasion and Metastasis. Gastroenterology. 2020;159:1882-1897.e5 pubmed 出版商
	D Anna F, Van Dyck L, Xiong J, Zhao H, Berrens R, Qian J, et al. DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumor immunotolerance. Genome Biol. 2020;21:182 pubmed 出版商
	Olcina M, Balanis N, Kim R, Aksoy B, Kodysh J, Thompson M, et al. Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer. Cell Rep. 2018;25:3721-3732.e6 pubmed 出版商
	Samanta D, Park Y, Ni X, Li H, Zahnow C, Gabrielson E, et al. Chemotherapy induces enrichment of CD47+/CD73+/PDL1+ immune evasive triple-negative breast cancer cells. Proc Natl Acad Sci U S A. 2018;115:E1239-E1248 pubmed 出版商
	Lu H, Chen I, Shimoda L, Park Y, Zhang C, Tran L, et al. Chemotherapy-Induced Ca2+ Release Stimulates Breast Cancer Stem Cell Enrichment. Cell Rep. 2017;18:1946-1957 pubmed 出版商
	Ju J, Godet I, Ye I, Byun J, Jayatilaka H, Lee S, et al. Hypoxia Selectively Enhances Integrin ?5?1 Receptor Expression in Breast Cancer to Promote Metastasis. Mol Cancer Res. 2017;15:723-734 pubmed 出版商
	Taylor S, Bagnall J, Mason D, Levy R, Fernig D, See V. Differential sub-nuclear distribution of hypoxia-inducible factors (HIF)-1 and -2 alpha impacts on their stability and mobility. Open Biol. 2016;6: pubmed
	Li S, Heller J, Bostick J, Lee A, Schjerven H, Kastner P, et al. Ikaros Inhibits Group 3 Innate Lymphoid Cell Development and Function by Suppressing the Aryl Hydrocarbon Receptor Pathway. Immunity. 2016;45:185-97 pubmed 出版商
	Frey J, Stonko D, Faugere M, Riddle R. Hypoxia-inducible factor-1α restricts the anabolic actions of parathyroid hormone. Bone Res. 2014;2:14005 pubmed 出版商
	Rossin F, D Eletto M, Falasca L, Sepe S, Cocco S, Fimia G, et al. Transglutaminase 2 ablation leads to mitophagy impairment associated with a metabolic shift towards aerobic glycolysis. Cell Death Differ. 2015;22:408-18 pubmed 出版商
	Autheman D, Sheldon R, Chaudhuri N, von Arx S, Siegenthaler C, Ferriero D, et al. Glutathione peroxidase overexpression causes aberrant ERK activation in neonatal mouse cortex after hypoxic preconditioning. Pediatr Res. 2012;72:568-75 pubmed 出版商
	Terzuoli E, Puppo M, Rapisarda A, Uranchimeg B, Cao L, Burger A, et al. Aminoflavone, a ligand of the aryl hydrocarbon receptor, inhibits HIF-1alpha expression in an AhR-independent fashion. Cancer Res. 2010;70:6837-48 pubmed 出版商
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产品信息

品牌 :

Novus Biologicals, a Bio-Techne Brand

catalog number base :

NB100-124

SKU号 :

NB100-124

产品名称 :

ARNT/HIF-1 beta Antibody (H1beta234) - BSA Free

描述 :

The ARNT/HIF-1 beta Antibody (H1beta234) - BSA Free from Novus is a mouse monoclonal antibody to ARNT/HIF-1 beta. This antibody reacts with human, mouse, rat, bovine, ferret, primate, sheep. The ARNT/HIF-1 beta Antibody (H1beta234) - BSA Free has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunoblotting, Gel Super Shift Assays, Chromatin Immunoprecipitation (ChIP), Chromatin Immunoprecipitation Sequencing.

靶标 :

ARNT/HIF-1乙

类别 :

一抗

单位尺寸 :

0.1 ml (also 0.025 ml)

缓冲液 :

PBS

克隆性 :

单克隆

克隆 :

H1beta234

浓度 :

1毫克/毫升

共轭标签 :

未共轭

宿主 :

小鼠

免疫原 :

ARNT/HIF-1 beta Antibody (H1beta234) was developed against a fusion protein containing amino acids 496-789 of human HIF-1 beta. [Uniprot: P27540]

抗体亚型 :

IgG1 Kappa

纯度 :

蛋白质G纯化

物种 :

人类, 小鼠, 大鼠, 牛, 白鼬, 灵长类动物, 羊

理论上的分子量 :

86.6 kDa

基因符号 :

ARNT

应用 :

Western Blot, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunoblotting, Gel Super Shift Assays, Chromatin Immunoprecipitation (ChIP), Chromatin Immunoprecipitation Sequencing

美元 :

449美元

别名 :

ARNT, ARNT protein, aryl hydrocarbon receptor nuclear translocator, BHLHE2, Class E Basic Helix-Loop-Helix Protein 2, Dioxin Receptor, Nuclear Translocator, HIF-1 Beta, HIF1B, HIF-1beta, HIF-1-beta, HIF1-beta, HIF1BETA, hypoxia-inducible factor 1, beta subunit, Hypoxia-inducible factor 1-beta, TANGO

储存 :

分成小份儿保存在-20C或-80C。避免冻融循环

更多信息或购买 :

Novus Biologicals 产品网页

公司信息

Novus Biologicals

10771 E Easter Ave
Centennial, CO 80112

technical@novusbio.com

https://www.novusbio.com

1-888-506-6887 303-730-1950

公司总部: 美国

Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。