| 出版应用/物种/样本/稀释 | 参考文献 |
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- 免疫组化-石蜡切片; 人类; 图 10a
- 免疫印迹; 人类; 图 9c
| Song K, Kim J, Lee Y, Bae H, Lee H, Woo S, et al. Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance. J Clin Invest. 2018;128:4098-4114 pubmed 出版商 |
| Ochi F, Shiozaki A, Ichikawa D, Fujiwara H, Nakashima S, Takemoto K, et al. Carbonic Anhydrase XII as an Independent Prognostic Factor in Advanced Esophageal Squamous Cell Carcinoma. J Cancer. 2015;6:922-9 pubmed 出版商 |
| Shankar G, Taylor Weiner A, Lelic N, Jones R, Kim J, FRANCIS J, et al. Sporadic hemangioblastomas are characterized by cryptic VHL inactivation. Acta Neuropathol Commun. 2014;2:167 pubmed 出版商 |
| Hempel C, Hoyer N, Kildemoes A, Jendresen C, Kurtzhals J. Systemic and Cerebral Vascular Endothelial Growth Factor Levels Increase in Murine Cerebral Malaria along with Increased Calpain and Caspase Activity and Can be Reduced by Erythropoietin Treatment. Front Immunol. 2014;5:291 pubmed 出版商 |
| Vasuri F, Fittipaldi S, Abualhin M, DeGiovanni A, Gargiulo M, Stella A, et al. Biochemical and immunomorphological evaluation of hepatocyte growth factor and c-Met pathway in patients with critical limb ischemia. Eur J Vasc Endovasc Surg. 2014;48:430-7 pubmed 出版商 |
- 免疫组化-冰冻切片; 小鼠
- 免疫细胞化学; 小鼠
- 免疫印迹; 小鼠
| Schaible E, Windschügl J, Bobkiewicz W, Kaburov Y, Dangel L, Kramer T, et al. 2-Methoxyestradiol confers neuroprotection and inhibits a maladaptive HIF-1? response after traumatic brain injury in mice. J Neurochem. 2014;129:940-54 pubmed 出版商 |
| Tajdini M, Mirbagheri S, Nikooie R, Ostovaneh M, Ghoreyshi Hefzabad S, Garg S, et al. Tissue hypoxia in pathogenesis of ulcerative colitis: should we change all our beliefs?. Scand J Gastroenterol. 2013;48:1487-8 pubmed 出版商 |
| Kim B, Cho H, Chung J, Conway C, Ylaya K, Kim J, et al. Prognostic assessment of hypoxia and metabolic markers in cervical cancer using automated digital image analysis of immunohistochemistry. J Transl Med. 2013;11:185 pubmed 出版商 |
| Liu M, Guo X, Wang S, Jin M, Wang Y, Li J, et al. BOLD-MRI of breast invasive ductal carcinoma: correlation of R2* value and the expression of HIF-1?. Eur Radiol. 2013;23:3221-7 pubmed 出版商 |
| Scott E, Boursiquot N, Beltran W, Dubielzig R. Early histopathologic changes in the retina and optic nerve in canine primary angle-closure glaucoma. Vet Ophthalmol. 2013;16 Suppl 1:79-86 pubmed 出版商 |
| Finger E, Cheng C, Williams T, Rankin E, Bedogni B, Tachiki L, et al. CTGF is a therapeutic target for metastatic melanoma. Oncogene. 2014;33:1093-100 pubmed 出版商 |
| Hu T, Beattie W, Mazer C, Leong Poi H, Fujii H, Wilson D, et al. Treatment with a highly selective ?? antagonist causes dose-dependent impairment of cerebral perfusion after hemodilution in rats. Anesth Analg. 2013;116:649-62 pubmed 出版商 |
| Rahimi A, Wilson D, Saylor D, Stelow E, Thomas C, Reibel J, et al. p16, Cyclin D1, and HIF-1? Predict Outcomes of Patients with Oropharyngeal Squamous Cell Carcinoma Treated with Definitive Intensity-Modulated Radiation Therapy. Int J Otolaryngol. 2012;2012:685951 pubmed 出版商 |
| Smeland E, Kilvaer T, Sorbye S, Valkov A, Andersen S, Bremnes R, et al. Prognostic impacts of hypoxic markers in soft tissue sarcoma. Sarcoma. 2012;2012:541650 pubmed 出版商 |
| Namas R, Metukuri M, Dhupar R, Velosa C, Jefferson B, Myer E, et al. Hypoxia-induced overexpression of BNIP3 is not dependent on hypoxia-inducible factor 1? in mouse hepatocytes. Shock. 2011;36:196-202 pubmed 出版商 |
| Halterman M. An improved method for the study of apoptosis-related genes using the tet-on system. J Biomol Screen. 2011;16:332-7 pubmed 出版商 |
| Lerman O, Greives M, Singh S, Thanik V, Chang C, Seiser N, et al. Low-dose radiation augments vasculogenesis signaling through HIF-1-dependent and -independent SDF-1 induction. Blood. 2010;116:3669-76 pubmed 出版商 |
| Arvidsson Y, Bergström A, Arvidsson L, Kristiansson E, Ahlman H, Nilsson O. Hypoxia stimulates CXCR4 signalling in ileal carcinoids. Endocr Relat Cancer. 2010;17:303-16 pubmed 出版商 |
| Ragoonanan T, Beattie W, Mazer C, Tsui A, Leong Poi H, Wilson D, et al. Metoprolol reduces cerebral tissue oxygen tension after acute hemodilution in rats. Anesthesiology. 2009;111:988-1000 pubmed 出版商 |
| Rasheed S, Harris A, Tekkis P, Turley H, Silver A, McDonald P, et al. Hypoxia-inducible factor-1alpha and -2alpha are expressed in most rectal cancers but only hypoxia-inducible factor-1alpha is associated with prognosis. Br J Cancer. 2009;100:1666-73 pubmed 出版商 |
| Pina Oviedo S, Khalili K, Del Valle L. Hypoxia inducible factor-1 alpha activation of the JCV promoter: role in the pathogenesis of progressive multifocal leukoencephalopathy. Acta Neuropathol. 2009;118:235-47 pubmed 出版商 |
| Dorević G, Matusan Ilijas K, Babarović E, Hadzisejdic I, Grahovac M, Grahovac B, et al. Hypoxia inducible factor-1alpha correlates with vascular endothelial growth factor A and C indicating worse prognosis in clear cell renal cell carcinoma. J Exp Clin Cancer Res. 2009;28:40 pubmed 出版商 |
| Rane S, He M, Sayed D, Vashistha H, Malhotra A, Sadoshima J, et al. Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes. Circ Res. 2009;104:879-86 pubmed 出版商 |
| Gomes E, Rodrigues M, Phadke A, Butcher L, Starling C, Chen S, et al. Antitumor activity of an oncolytic adenoviral-CD40 ligand (CD154) transgene construct in human breast cancer cells. Clin Cancer Res. 2009;15:1317-25 pubmed 出版商 |
| Viola R, Provenzale J, Li F, Li C, Yuan H, Tashjian J, et al. In vivo bioluminescence imaging monitoring of hypoxia-inducible factor 1alpha, a promoter that protects cells, in response to chemotherapy. AJR Am J Roentgenol. 2008;191:1779-84 pubmed 出版商 |
| Sutton T, Wilkinson J, Mang H, Knipe N, Plotkin Z, Hosein M, et al. p53 regulates renal expression of HIF-1{alpha} and pVHL under physiological conditions and after ischemia-reperfusion injury. Am J Physiol Renal Physiol. 2008;295:F1666-77 pubmed 出版商 |
| Reiser Erkan C, Erkan M, Pan Z, Bekasi S, Giese N, Streit S, et al. Hypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma. Cancer Biol Ther. 2008;7:1352-9 pubmed |
| Shimogai R, Kigawa J, Itamochi H, Iba T, Kanamori Y, Oishi T, et al. Expression of hypoxia-inducible factor 1alpha gene affects the outcome in patients with ovarian cancer. Int J Gynecol Cancer. 2008;18:499-505 pubmed 出版商 |
| Hartmann H, Eltzschig H, Wurz H, Hantke K, Rakin A, Yazdi A, et al. Hypoxia-independent activation of HIF-1 by enterobacteriaceae and their siderophores. Gastroenterology. 2008;134:756-67 pubmed 出版商 |
- 免疫组化-冰冻切片; 人类
- 免疫组化-石蜡切片; 人类
- 免疫组化; 人类
| Piovan E, Tosello V, Indraccolo S, Masiero M, Persano L, Esposito G, et al. Differential regulation of hypoxia-induced CXCR4 triggering during B-cell development and lymphomagenesis. Cancer Res. 2007;67:8605-14 pubmed |
| Lee S, Garner E, Welch W, Berkowitz R, Mok S. Over-expression of hypoxia-inducible factor 1 alpha in ovarian clear cell carcinoma. Gynecol Oncol. 2007;106:311-7 pubmed |
- 免疫组化-石蜡切片; 大鼠
- 免疫细胞化学; 大鼠
- 免疫组化; 大鼠
| Khan Z, Michalopoulos G, Stolz D. Peroxisomal localization of hypoxia-inducible factors and hypoxia-inducible factor regulatory hydroxylases in primary rat hepatocytes exposed to hypoxia-reoxygenation. Am J Pathol. 2006;169:1251-69 pubmed |
| Carroll P, Kenerson H, Yeung R, Lagunoff M. Latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells activates hypoxia-induced factors. J Virol. 2006;80:10802-12 pubmed |
| Ardyanto T, Osaki M, Tokuyasu N, Nagahama Y, Ito H. CoCl2-induced HIF-1alpha expression correlates with proliferation and apoptosis in MKN-1 cells: a possible role for the PI3K/Akt pathway. Int J Oncol. 2006;29:549-55 pubmed |
| Lidgren A, Hedberg Y, Grankvist K, Rasmuson T, Bergh A, Ljungberg B. Hypoxia-inducible factor 1alpha expression in renal cell carcinoma analyzed by tissue microarray. Eur Urol. 2006;50:1272-7 pubmed |
| Abbate A, Santini D, Biondi Zoccai G, Scarpa S, Vasaturo F, Liuzzo G, et al. Cyclo-oxygenase-2 (COX-2) expression at the site of recent myocardial infarction: friend or foe?. Heart. 2004;90:440-3 pubmed |
| Beasley N, Leek R, Alam M, Turley H, Cox G, Gatter K, et al. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients. Cancer Res. 2002;62:2493-7 pubmed |
| Giatromanolaki A, Koukourakis M, Sivridis E, Pastorek J, Wykoff C, Gatter K, et al. Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer. Cancer Res. 2001;61:7992-8 pubmed |
| Koukourakis M, Giatromanolaki A, Skarlatos J, Corti L, Blandamura S, Piazza M, et al. Hypoxia inducible factor (HIF-1a and HIF-2a) expression in early esophageal cancer and response to photodynamic therapy and radiotherapy. Cancer Res. 2001;61:1830-2 pubmed |
| Talks K, Turley H, Gatter K, Maxwell P, Pugh C, Ratcliffe P, et al. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol. 2000;157:411-21 pubmed |
| Otsuka S, Sakakima H, Terashi T, Takada S, Nakanishi K, Kikuchi K. Preconditioning exercise reduces brain damage and neuronal apoptosis through enhanced endogenous 14-3-3γ after focal brain ischemia in rats. Brain Struct Funct. 2019;224:727-738 pubmed 出版商 |
| Daskalakis K, Kaltsas G, Oberg K, Tsolakis A. Lung Carcinoids: Long-Term Surgical Results and the Lack of Prognostic Value of Somatostatin Receptors and Other Novel Immunohistochemical Markers. Neuroendocrinology. 2018;107:355-365 pubmed 出版商 |
| Hubbard W, Lashof Sullivan M, Greenberg S, Norris C, Eck J, Lavik E, et al. Hemostatic nanoparticles increase survival, mitigate neuropathology and alleviate anxiety in a rodent blast trauma model. Sci Rep. 2018;8:10622 pubmed 出版商 |
| Kanakis G, Grimelius L, Papaioannou D, Kaltsas G, Tsolakis A. Can insulin-like growth factor 1 (IGF-1), IGF-1 receptor connective tissue growth factor and Ki-67 labelling index have a prognostic role in pulmonary carcinoids?. Oncotarget. 2018;9:22653-22664 pubmed 出版商 |
| Jayabal P, Houghton P, Shiio Y. EWS-FLI-1 creates a cell surface microenvironment conducive to IGF signaling by inducing pappalysin-1. Genes Cancer. 2017;8:762-770 pubmed 出版商 |
| Toblli J, Cao G, Giani J, Dominici F, Angerosa M. Markers of oxidative/nitrosative stress and inflammation in lung tissue of rats exposed to different intravenous iron compounds. Drug Des Devel Ther. 2017;11:2251-2263 pubmed 出版商 |
| Gustafsson H, Kale A, Daşu A, Lund A, Edqvist P, Roberg K. EPR Oximetry of Cetuximab-Treated Head-and-Neck Tumours in a Mouse Model. Cell Biochem Biophys. 2017;75:299-309 pubmed 出版商 |
| Westerlund I, Shi Y, Toskas K, Fell S, Li S, Surova O, et al. Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression. Proc Natl Acad Sci U S A. 2017;114:E6137-E6146 pubmed 出版商 |
| McKelvie P, de Leval L, Edlefsen K, Ko Y, Aberman Z, Kovach A, et al. Fibrin-associated EBV-positive Large B-Cell Lymphoma: An Indolent Neoplasm With Features Distinct From Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation. Am J Surg Pathol. 2017;41:299-312 pubmed 出版商 |
| Siebenmann C, Keramidas M, Rundqvist H, Mijwel S, Cowburn A, Johnson R, et al. Cutaneous exposure to hypoxia does not affect skin perfusion in humans. Acta Physiol (Oxf). 2017;220:361-369 pubmed 出版商 |
| Cahill L, Gazdzinski L, Tsui A, Zhou Y, Portnoy S, Liu E, et al. Functional and anatomical evidence of cerebral tissue hypoxia in young sickle cell anemia mice. J Cereb Blood Flow Metab. 2017;37:994-1005 pubmed 出版商 |
| Huang T, Chung S, Chua S, Chai H, Sheu J, Chen Y, et al. Effect of early administration of lower dose versus high dose of fresh mitochondria on reducing monocrotaline-induced pulmonary artery hypertension in rat. Am J Transl Res. 2016;8:5151-5168 pubmed |
| Hjelmgren O, Gellerman K, Kjelldahl J, Lindahl P, Bergström G. Increased Vascularization in the Vulnerable Upstream Regions of Both Early and Advanced Human Carotid Atherosclerosis. PLoS ONE. 2016;11:e0166918 pubmed 出版商 |
| Koh J, Jang J, Keam B, Kim S, Kim M, Go H, et al. EML4-ALK enhances programmed cell death-ligand 1 expression in pulmonary adenocarcinoma via hypoxia-inducible factor (HIF)-1α and STAT3. Oncoimmunology. 2016;5:e1108514 pubmed |
| Miller A, Deal D, Green J, Houle T, Brown W, Thore C, et al. Use of the Reamer/Irrigator/Aspirator Decreases Carotid and Cranial Embolic Events in a Canine Model. J Bone Joint Surg Am. 2016;98:658-64 pubmed 出版商 |
| Fan Y, Li H, Ma X, Gao Y, Bao X, Du Q, et al. Dicer suppresses the malignant phenotype in VHL-deficient clear cell renal cell carcinoma by inhibiting HIF-2α. Oncotarget. 2016;7:18280-94 pubmed 出版商 |
| Kim Y, Nam H, Lee J, Park D, Kim C, Yu Y, et al. Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis. Nat Commun. 2016;7:10347 pubmed 出版商 |
| Shi X, Guo L, Seedial S, Si Y, Wang B, Takayama T, et al. TGF-?/Smad3 inhibit vascular smooth muscle cell apoptosis through an autocrine signaling mechanism involving VEGF-A. Cell Death Dis. 2014;5:e1317 pubmed 出版商 |
| Stenvold H, Donnem T, Andersen S, Al Saad S, Valkov A, Pedersen M, et al. High tumor cell expression of microRNA-21 in node positive non-small cell lung cancer predicts a favorable clinical outcome. BMC Clin Pathol. 2014;14:9 pubmed 出版商 |
| Maeda A, Nakata M, Yasuda K, Yukawa T, Saisho S, Okita R, et al. Influence of vascular endothelial growth factor single nucleotide polymorphisms on non-small cell lung cancer tumor angiogenesis. Oncol Rep. 2013;29:39-44 pubmed 出版商 |
| Rezvani H, Ali N, Serrano Sanchez M, Dubus P, Varon C, Ged C, et al. Loss of epidermal hypoxia-inducible factor-1? accelerates epidermal aging and affects re-epithelialization in human and mouse. J Cell Sci. 2011;124:4172-83 pubmed 出版商 |
| Le Lay S, Rodriguez M, Jessup W, Rentero C, Li Q, Cartland S, et al. Caveolin-1-mediated apolipoprotein A-I membrane binding sites are not required for cholesterol efflux. PLoS ONE. 2011;6:e23353 pubmed 出版商 |
| Eckert A, Lautner M, Schutze A, Taubert H, Schubert J, Bilkenroth U. Coexpression of hypoxia-inducible factor-1? and glucose transporter-1 is associated with poor prognosis in oral squamous cell carcinoma patients. Histopathology. 2011;58:1136-47 pubmed 出版商 |
| Andersen S, Eilertsen M, Donnem T, Al Shibli K, Al Saad S, Busund L, et al. Diverging prognostic impacts of hypoxic markers according to NSCLC histology. Lung Cancer. 2011;72:294-302 pubmed 出版商 |
| Park S, Ha S, Cho H, Chung D, Kim N, Hong J, et al. Prognostic implications of hypoxia-inducible factor-1? in epidermal growth factor receptor-negative non-small cell lung cancer. Lung Cancer. 2011;72:100-7 pubmed 出版商 |
| Bennecke M, Kriegl L, Bajbouj M, Retzlaff K, Robine S, Jung A, et al. Ink4a/Arf and oncogene-induced senescence prevent tumor progression during alternative colorectal tumorigenesis. Cancer Cell. 2010;18:135-46 pubmed 出版商 |
| Lei Z, Li B, Yang Z, Fang H, Zhang G, Feng Z, et al. Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration. PLoS ONE. 2009;4:e7629 pubmed 出版商 |
| Kanasaki K, Palmsten K, Sugimoto H, Ahmad S, Hamano Y, Xie L, et al. Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia. Nature. 2008;453:1117-21 pubmed 出版商 |
| Kubo T, Sugita T, Shimose S, Matsuo T, Arihiro K, Ochi M. Expression of hypoxia-inducible factor-1alpha and its relationship to tumour angiogenesis and cell proliferation in cartilage tumours. J Bone Joint Surg Br. 2008;90:364-70 pubmed 出版商 |
| Monsef N, Helczynski L, Lundwall A, Påhlman S. Localization of immunoreactive HIF-1alpha and HIF-2alpha in neuroendocrine cells of both benign and malignant prostate glands. Prostate. 2007;67:1219-29 pubmed |
| Kyriacou H, Steen K, Raza A, Arman M, Warimwe G, Bull P, et al. In vitro inhibition of Plasmodium falciparum rosette formation by Curdlan sulfate. Antimicrob Agents Chemother. 2007;51:1321-6 pubmed |
| Choke E, Cockerill G, Dawson J, Chung Y, Griffiths J, Wilson R, et al. Hypoxia at the site of abdominal aortic aneurysm rupture is not associated with increased lactate. Ann N Y Acad Sci. 2006;1085:306-10 pubmed |
| Hirami Y, Aoe M, Tsukuda K, Hara F, Otani Y, Koshimune R, et al. Relation of epidermal growth factor receptor, phosphorylated-Akt, and hypoxia-inducible factor-1alpha in non-small cell lung cancers. Cancer Lett. 2004;214:157-64 pubmed |
| Wiesener M, Turley H, Allen W, Willam C, Eckardt K, Talks K, et al. Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha. Blood. 1998;92:2260-8 pubmed |
