产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
小鼠单克隆HIF-1甲抗体
目录 :
NB100-131
规格 :
0.1 ml (also 0.025 ml)
价格 :
349美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
ESEE122
反应物种 :
人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 57
出版应用/物种/样品/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 图 10a
  • 免疫印迹; 人类; 图 9c
Song K, Kim J, Lee Y, Bae H, Lee H, Woo S, et al. Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance. J Clin Invest. 2018;128:4098-4114 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 2
Ochi F, Shiozaki A, Ichikawa D, Fujiwara H, Nakashima S, Takemoto K, et al. Carbonic Anhydrase XII as an Independent Prognostic Factor in Advanced Esophageal Squamous Cell Carcinoma. J Cancer. 2015;6:922-9 pubmed 出版商
  • 免疫组化; 人类
  • 免疫组化; scFv
Shankar G, Taylor Weiner A, Lelic N, Jones R, Kim J, FRANCIS J, et al. Sporadic hemangioblastomas are characterized by cryptic VHL inactivation. Acta Neuropathol Commun. 2014;2:167 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 2
Hempel C, Hoyer N, Kildemoes A, Jendresen C, Kurtzhals J. Systemic and Cerebral Vascular Endothelial Growth Factor Levels Increase in Murine Cerebral Malaria along with Increased Calpain and Caspase Activity and Can be Reduced by Erythropoietin Treatment. Front Immunol. 2014;5:291 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Vasuri F, Fittipaldi S, Abualhin M, DeGiovanni A, Gargiulo M, Stella A, et al. Biochemical and immunomorphological evaluation of hepatocyte growth factor and c-Met pathway in patients with critical limb ischemia. Eur J Vasc Endovasc Surg. 2014;48:430-7 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
  • 免疫细胞化学; 小鼠
  • 免疫印迹; 小鼠
Schaible E, Windschügl J, Bobkiewicz W, Kaburov Y, Dangel L, Kramer T, et al. 2-Methoxyestradiol confers neuroprotection and inhibits a maladaptive HIF-1? response after traumatic brain injury in mice. J Neurochem. 2014;129:940-54 pubmed 出版商
  • 免疫组化; 人类
Tajdini M, Mirbagheri S, Nikooie R, Ostovaneh M, Ghoreyshi Hefzabad S, Garg S, et al. Tissue hypoxia in pathogenesis of ulcerative colitis: should we change all our beliefs?. Scand J Gastroenterol. 2013;48:1487-8 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Kim B, Cho H, Chung J, Conway C, Ylaya K, Kim J, et al. Prognostic assessment of hypoxia and metabolic markers in cervical cancer using automated digital image analysis of immunohistochemistry. J Transl Med. 2013;11:185 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Liu M, Guo X, Wang S, Jin M, Wang Y, Li J, et al. BOLD-MRI of breast invasive ductal carcinoma: correlation of R2* value and the expression of HIF-1?. Eur Radiol. 2013;23:3221-7 pubmed 出版商
  • 免疫组化; 狗
Scott E, Boursiquot N, Beltran W, Dubielzig R. Early histopathologic changes in the retina and optic nerve in canine primary angle-closure glaucoma. Vet Ophthalmol. 2013;16 Suppl 1:79-86 pubmed 出版商
  • 免疫印迹; 人类
Finger E, Cheng C, Williams T, Rankin E, Bedogni B, Tachiki L, et al. CTGF is a therapeutic target for metastatic melanoma. Oncogene. 2014;33:1093-100 pubmed 出版商
  • 免疫细胞化学; 大鼠
  • 免疫组化; 大鼠
Hu T, Beattie W, Mazer C, Leong Poi H, Fujii H, Wilson D, et al. Treatment with a highly selective ?? antagonist causes dose-dependent impairment of cerebral perfusion after hemodilution in rats. Anesth Analg. 2013;116:649-62 pubmed 出版商
  • 免疫组化; 人类
Rahimi A, Wilson D, Saylor D, Stelow E, Thomas C, Reibel J, et al. p16, Cyclin D1, and HIF-1? Predict Outcomes of Patients with Oropharyngeal Squamous Cell Carcinoma Treated with Definitive Intensity-Modulated Radiation Therapy. Int J Otolaryngol. 2012;2012:685951 pubmed 出版商
  • 免疫组化; 人类
Smeland E, Kilvaer T, Sorbye S, Valkov A, Andersen S, Bremnes R, et al. Prognostic impacts of hypoxic markers in soft tissue sarcoma. Sarcoma. 2012;2012:541650 pubmed 出版商
  • 免疫印迹; 小鼠
Namas R, Metukuri M, Dhupar R, Velosa C, Jefferson B, Myer E, et al. Hypoxia-induced overexpression of BNIP3 is not dependent on hypoxia-inducible factor 1? in mouse hepatocytes. Shock. 2011;36:196-202 pubmed 出版商
  • 免疫印迹; 小鼠
Halterman M. An improved method for the study of apoptosis-related genes using the tet-on system. J Biomol Screen. 2011;16:332-7 pubmed 出版商
  • 免疫细胞化学; 人类
Lerman O, Greives M, Singh S, Thanik V, Chang C, Seiser N, et al. Low-dose radiation augments vasculogenesis signaling through HIF-1-dependent and -independent SDF-1 induction. Blood. 2010;116:3669-76 pubmed 出版商
  • 免疫组化; 人类
Arvidsson Y, Bergström A, Arvidsson L, Kristiansson E, Ahlman H, Nilsson O. Hypoxia stimulates CXCR4 signalling in ileal carcinoids. Endocr Relat Cancer. 2010;17:303-16 pubmed 出版商
  • 免疫印迹; 大鼠
Ragoonanan T, Beattie W, Mazer C, Tsui A, Leong Poi H, Wilson D, et al. Metoprolol reduces cerebral tissue oxygen tension after acute hemodilution in rats. Anesthesiology. 2009;111:988-1000 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Rasheed S, Harris A, Tekkis P, Turley H, Silver A, McDonald P, et al. Hypoxia-inducible factor-1alpha and -2alpha are expressed in most rectal cancers but only hypoxia-inducible factor-1alpha is associated with prognosis. Br J Cancer. 2009;100:1666-73 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
  • 免疫细胞化学; 人类
Pina Oviedo S, Khalili K, Del Valle L. Hypoxia inducible factor-1 alpha activation of the JCV promoter: role in the pathogenesis of progressive multifocal leukoencephalopathy. Acta Neuropathol. 2009;118:235-47 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
  • 免疫组化; 人类
Dorević G, Matusan Ilijas K, Babarović E, Hadzisejdic I, Grahovac M, Grahovac B, et al. Hypoxia inducible factor-1alpha correlates with vascular endothelial growth factor A and C indicating worse prognosis in clear cell renal cell carcinoma. J Exp Clin Cancer Res. 2009;28:40 pubmed 出版商
  • 免疫细胞化学; 大鼠
Rane S, He M, Sayed D, Vashistha H, Malhotra A, Sadoshima J, et al. Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes. Circ Res. 2009;104:879-86 pubmed 出版商
  • 免疫组化; 人类
Gomes E, Rodrigues M, Phadke A, Butcher L, Starling C, Chen S, et al. Antitumor activity of an oncolytic adenoviral-CD40 ligand (CD154) transgene construct in human breast cancer cells. Clin Cancer Res. 2009;15:1317-25 pubmed 出版商
  • 免疫组化; 小鼠
Viola R, Provenzale J, Li F, Li C, Yuan H, Tashjian J, et al. In vivo bioluminescence imaging monitoring of hypoxia-inducible factor 1alpha, a promoter that protects cells, in response to chemotherapy. AJR Am J Roentgenol. 2008;191:1779-84 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠
  • 免疫组化; 大鼠
Sutton T, Wilkinson J, Mang H, Knipe N, Plotkin Z, Hosein M, et al. p53 regulates renal expression of HIF-1{alpha} and pVHL under physiological conditions and after ischemia-reperfusion injury. Am J Physiol Renal Physiol. 2008;295:F1666-77 pubmed 出版商
  • 免疫印迹; 人类
Reiser Erkan C, Erkan M, Pan Z, Bekasi S, Giese N, Streit S, et al. Hypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma. Cancer Biol Ther. 2008;7:1352-9 pubmed
  • 免疫组化-石蜡切片; 人类
Shimogai R, Kigawa J, Itamochi H, Iba T, Kanamori Y, Oishi T, et al. Expression of hypoxia-inducible factor 1alpha gene affects the outcome in patients with ovarian cancer. Int J Gynecol Cancer. 2008;18:499-505 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
  • 免疫印迹; 小鼠
Hartmann H, Eltzschig H, Wurz H, Hantke K, Rakin A, Yazdi A, et al. Hypoxia-independent activation of HIF-1 by enterobacteriaceae and their siderophores. Gastroenterology. 2008;134:756-67 pubmed 出版商
  • 免疫组化-冰冻切片; 人类
  • 免疫组化-石蜡切片; 人类
  • 免疫组化; 人类
Piovan E, Tosello V, Indraccolo S, Masiero M, Persano L, Esposito G, et al. Differential regulation of hypoxia-induced CXCR4 triggering during B-cell development and lymphomagenesis. Cancer Res. 2007;67:8605-14 pubmed
  • 免疫组化-石蜡切片; 人类
Lee S, Garner E, Welch W, Berkowitz R, Mok S. Over-expression of hypoxia-inducible factor 1 alpha in ovarian clear cell carcinoma. Gynecol Oncol. 2007;106:311-7 pubmed
  • 免疫组化-石蜡切片; 大鼠
  • 免疫细胞化学; 大鼠
  • 免疫组化; 大鼠
Khan Z, Michalopoulos G, Stolz D. Peroxisomal localization of hypoxia-inducible factors and hypoxia-inducible factor regulatory hydroxylases in primary rat hepatocytes exposed to hypoxia-reoxygenation. Am J Pathol. 2006;169:1251-69 pubmed
  • 免疫组化-石蜡切片; 人类
  • 免疫组化; 人类
Carroll P, Kenerson H, Yeung R, Lagunoff M. Latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells activates hypoxia-induced factors. J Virol. 2006;80:10802-12 pubmed
  • 免疫印迹; 人类
Ardyanto T, Osaki M, Tokuyasu N, Nagahama Y, Ito H. CoCl2-induced HIF-1alpha expression correlates with proliferation and apoptosis in MKN-1 cells: a possible role for the PI3K/Akt pathway. Int J Oncol. 2006;29:549-55 pubmed
  • 免疫组化; 人类
Lidgren A, Hedberg Y, Grankvist K, Rasmuson T, Bergh A, Ljungberg B. Hypoxia-inducible factor 1alpha expression in renal cell carcinoma analyzed by tissue microarray. Eur Urol. 2006;50:1272-7 pubmed
  • 免疫组化-石蜡切片; 人类
Abbate A, Santini D, Biondi Zoccai G, Scarpa S, Vasaturo F, Liuzzo G, et al. Cyclo-oxygenase-2 (COX-2) expression at the site of recent myocardial infarction: friend or foe?. Heart. 2004;90:440-3 pubmed
  • 免疫组化-石蜡切片; 人类
Beasley N, Leek R, Alam M, Turley H, Cox G, Gatter K, et al. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients. Cancer Res. 2002;62:2493-7 pubmed
  • 免疫组化-石蜡切片; 人类
Giatromanolaki A, Koukourakis M, Sivridis E, Pastorek J, Wykoff C, Gatter K, et al. Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer. Cancer Res. 2001;61:7992-8 pubmed
  • 免疫组化-石蜡切片; 人类
Koukourakis M, Giatromanolaki A, Skarlatos J, Corti L, Blandamura S, Piazza M, et al. Hypoxia inducible factor (HIF-1a and HIF-2a) expression in early esophageal cancer and response to photodynamic therapy and radiotherapy. Cancer Res. 2001;61:1830-2 pubmed
  • 免疫组化-石蜡切片; 人类
  • 免疫印迹; 人类
Talks K, Turley H, Gatter K, Maxwell P, Pugh C, Ratcliffe P, et al. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol. 2000;157:411-21 pubmed
Westerlund I, Shi Y, Toskas K, Fell S, Li S, Surova O, et al. Combined epigenetic and differentiation-based treatment inhibits neuroblastoma tumor growth and links HIF2α to tumor suppression. Proc Natl Acad Sci U S A. 2017;114:E6137-E6146 pubmed 出版商
Stenvold H, Donnem T, Andersen S, Al Saad S, Valkov A, Pedersen M, et al. High tumor cell expression of microRNA-21 in node positive non-small cell lung cancer predicts a favorable clinical outcome. BMC Clin Pathol. 2014;14:9 pubmed 出版商
Maeda A, Nakata M, Yasuda K, Yukawa T, Saisho S, Okita R, et al. Influence of vascular endothelial growth factor single nucleotide polymorphisms on non-small cell lung cancer tumor angiogenesis. Oncol Rep. 2013;29:39-44 pubmed 出版商
Rezvani H, Ali N, Serrano Sanchez M, Dubus P, Varon C, Ged C, et al. Loss of epidermal hypoxia-inducible factor-1? accelerates epidermal aging and affects re-epithelialization in human and mouse. J Cell Sci. 2011;124:4172-83 pubmed 出版商
Le Lay S, Rodriguez M, Jessup W, Rentero C, Li Q, Cartland S, et al. Caveolin-1-mediated apolipoprotein A-I membrane binding sites are not required for cholesterol efflux. PLoS ONE. 2011;6:e23353 pubmed 出版商
Eckert A, Lautner M, Schutze A, Taubert H, Schubert J, Bilkenroth U. Coexpression of hypoxia-inducible factor-1? and glucose transporter-1 is associated with poor prognosis in oral squamous cell carcinoma patients. Histopathology. 2011;58:1136-47 pubmed 出版商
Andersen S, Eilertsen M, Donnem T, Al Shibli K, Al Saad S, Busund L, et al. Diverging prognostic impacts of hypoxic markers according to NSCLC histology. Lung Cancer. 2011;72:294-302 pubmed 出版商
Park S, Ha S, Cho H, Chung D, Kim N, Hong J, et al. Prognostic implications of hypoxia-inducible factor-1? in epidermal growth factor receptor-negative non-small cell lung cancer. Lung Cancer. 2011;72:100-7 pubmed 出版商
Bennecke M, Kriegl L, Bajbouj M, Retzlaff K, Robine S, Jung A, et al. Ink4a/Arf and oncogene-induced senescence prevent tumor progression during alternative colorectal tumorigenesis. Cancer Cell. 2010;18:135-46 pubmed 出版商
Lei Z, Li B, Yang Z, Fang H, Zhang G, Feng Z, et al. Regulation of HIF-1alpha and VEGF by miR-20b tunes tumor cells to adapt to the alteration of oxygen concentration. PLoS ONE. 2009;4:e7629 pubmed 出版商
Kanasaki K, Palmsten K, Sugimoto H, Ahmad S, Hamano Y, Xie L, et al. Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia. Nature. 2008;453:1117-21 pubmed 出版商
Kubo T, Sugita T, Shimose S, Matsuo T, Arihiro K, Ochi M. Expression of hypoxia-inducible factor-1alpha and its relationship to tumour angiogenesis and cell proliferation in cartilage tumours. J Bone Joint Surg Br. 2008;90:364-70 pubmed 出版商
Monsef N, Helczynski L, Lundwall A, Påhlman S. Localization of immunoreactive HIF-1alpha and HIF-2alpha in neuroendocrine cells of both benign and malignant prostate glands. Prostate. 2007;67:1219-29 pubmed
Kyriacou H, Steen K, Raza A, Arman M, Warimwe G, Bull P, et al. In vitro inhibition of Plasmodium falciparum rosette formation by Curdlan sulfate. Antimicrob Agents Chemother. 2007;51:1321-6 pubmed
Choke E, Cockerill G, Dawson J, Chung Y, Griffiths J, Wilson R, et al. Hypoxia at the site of abdominal aortic aneurysm rupture is not associated with increased lactate. Ann N Y Acad Sci. 2006;1085:306-10 pubmed
Hirami Y, Aoe M, Tsukuda K, Hara F, Otani Y, Koshimune R, et al. Relation of epidermal growth factor receptor, phosphorylated-Akt, and hypoxia-inducible factor-1alpha in non-small cell lung cancers. Cancer Lett. 2004;214:157-64 pubmed
Wiesener M, Turley H, Allen W, Willam C, Eckardt K, Talks K, et al. Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha. Blood. 1998;92:2260-8 pubmed
产品信息
SKU号 :
NB100-131
产品名称 :
小鼠单克隆HIF-1甲抗体
规格 :
0.1 ml (also 0.025 ml)
描述 :
The HIF-1 alpha Antibody (ESEE122) from Novus Biologicals is a mouse monoclonal antibody to HIF-1 alpha. This antibody reacts with human, mouse, rat, bovine, canine. The HIF-1 alpha Antibody (ESEE122) has been validated for the following applications: Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
靶标 :
HIF-1甲
类别 :
一抗
缓冲液 :
三羟甲基氨基甲烷甘氨酸, 0.15M氯化钠
克隆性 :
单克隆
克隆 :
ESEE122
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
Human HIF-1 alpha, corresponding to amino acids 329 - 530 [UniProt# Q16665].
抗体亚型 :
IgG1
纯度 :
蛋白质G纯化
物种活性 :
人类, 小鼠, 大鼠, 牛, 狗
Theoretical Molecular Weight :
93 kDa
基因符号 :
缺氧诱导因子1A
应用 :
Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
价格 :
349美元
又名 :
ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, BHLHE78, Class E basic helix-loop-helix protein 78, HIF-1 alpha, HIF1A, HIF-1-alpha, HIF1-alpha, hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), hypoxia-inducible factor 1-alpha, Member of PAS protein 1, member of PAS superfamily 1, MOP1HIF1-ALPHA, PAS domain-containing protein 8, PASD8alpha subunit (basic helix-loop-helix transcription factor)
储存 :
分成小份儿保存在-20C或-80C。 避免冻融循环
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。