产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
HIF-1甲抗体
目录 :
NB100-134
规格 :
0.1毫升
价格 :
349美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠, 大鼠, , 斑马鱼
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 85
出版应用/物种/样品/稀释参考文献
  • 免疫印迹; 小鼠; 图 4b
Cheng Y, Sun M, Chen L, Li Y, Lin L, Yao B, et al. Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice. Cell Rep. 2018;25:3194-3203.e4 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 s4e
Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al. AMP kinase promotes glioblastoma bioenergetics and tumour growth. Nat Cell Biol. 2018;20:823-835 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 3a
Yuan X, Qi H, Li X, Wu F, Fang J, Bober E, et al. Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice. J Clin Invest. 2017;127:2235-2248 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Murakami A, Wang L, Kalhorn S, Schraml P, Rathmell W, Tan A, et al. Context-dependent role for chromatin remodeling component PBRM1/BAF180 in clear cell renal cell carcinoma. Oncogenesis. 2017;6:e287 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 4f
Salvi V, Vermi W, Gianello V, Lonardi S, Gagliostro V, Naldini A, et al. Dendritic cell-derived VEGF-A plays a role in inflammatory angiogenesis of human secondary lymphoid organs and is driven by the coordinated activation of multiple transcription factors. Oncotarget. 2016;7:39256-39269 pubmed 出版商
  • 免疫组化-石蜡切片; 狗; 1:500; 图 5
Spitzbarth I, Lempp C, Kegler K, Ulrich R, Kalkuhl A, Deschl U, et al. Immunohistochemical and transcriptome analyses indicate complex breakdown of axonal transport mechanisms in canine distemper leukoencephalitis. Brain Behav. 2016;6:e00472 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠
Semba H, Takeda N, Isagawa T, Sugiura Y, Honda K, Wake M, et al. HIF-1?-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity. Nat Commun. 2016;7:11635 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 图 3
  • 免疫印迹; 人类; 图 3
Mori H, Yao Y, Learman B, Kurozumi K, Ishida J, Ramakrishnan S, et al. Induction of WNT11 by hypoxia and hypoxia-inducible factor-1α regulates cell proliferation, migration and invasion. Sci Rep. 2016;6:21520 pubmed 出版商
  • 免疫沉淀; 人类; 1:200; 图 2f
  • 免疫印迹; 人类; 1:1000; 图 2f
Lin A, Li C, Xing Z, Hu Q, Liang K, Han L, et al. The LINK-A lncRNA activates normoxic HIF1? signalling in triple-negative breast cancer. Nat Cell Biol. 2016;18:213-24 pubmed 出版商
  • 免疫印迹; 人类; 图 1
de Jong O, van Balkom B, Gremmels H, Verhaar M. Exosomes from hypoxic endothelial cells have increased collagen crosslinking activity through up-regulation of lysyl oxidase-like 2. J Cell Mol Med. 2016;20:342-50 pubmed 出版商
  • 免疫印迹; 大鼠
  • 免疫印迹; 小鼠; 1:600
Hung Y, Chang S, Huang C, Yin J, Hwang C, Yang L, et al. Inhibitor of Differentiation-1 and Hypoxia-Inducible Factor-1 Mediate Sonic Hedgehog Induction by Amyloid Beta-Peptide in Rat Cortical Neurons. Mol Neurobiol. 2016;53:793-809 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7c
  • 免疫印迹; 人类; 图 5d
Chen P, Weng J, Hsu P, Shew J, Huang Y, Lee W. NPGPx modulates CPEB2-controlled HIF-1α RNA translation in response to oxidative stress. Nucleic Acids Res. 2015;43:9393-404 pubmed 出版商
  • 免疫组化; 人类; 表 2
  • 免疫印迹; 人类; 表 2
Park I, Chung P, Ahn J. Enhancement of Ischemic Wound Healing by Spheroid Grafting of Human Adipose-Derived Stem Cells Treated with Low-Level Light Irradiation. PLoS ONE. 2015;10:e0122776 pubmed 出版商
  • 免疫印迹; 小鼠
Forristal C, Brown A, Helwani F, Winkler I, Nowlan B, Barbier V, et al. Hypoxia inducible factor (HIF)-2α accelerates disease progression in mouse models of leukemia and lymphoma but is not a poor prognosis factor in human AML. Leukemia. 2015;29:2075-85 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Saeedi B, Kao D, Kitzenberg D, Dobrinskikh E, Schwisow K, Masterson J, et al. HIF-dependent regulation of claudin-1 is central to intestinal epithelial tight junction integrity. Mol Biol Cell. 2015;26:2252-62 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 2
Koh H, Chang C, Jeon S, Yoon H, Ahn Y, Kim H, et al. The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia. Nat Commun. 2015;6:6340 pubmed 出版商
  • 免疫印迹; 小鼠
García L, Leimgruber C, Uribe Echevarría E, Acosta P, Brahamian J, Polack F, et al. Protective phenotypes of club cells and alveolar macrophages are favored as part of endotoxin-mediated prevention of asthma. Exp Biol Med (Maywood). 2015;240:904-16 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠
Sun K, Chen M, Tu M, Wang I, Chang S, Li C. MicroRNA-20a regulates autophagy related protein-ATG16L1 in hypoxia-induced osteoclast differentiation. Bone. 2015;73:145-53 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Khamaisi M, Toukan H, Axelrod J, Rosenberger C, Skarzinski G, Shina A, et al. Endothelin-converting enzyme is a plausible target gene for hypoxia-inducible factor. Kidney Int. 2015;87:761-70 pubmed 出版商
  • 免疫印迹; 人类
Robertson E, Wasylyk C, Ye T, Jung A, Wasylyk B. The oncogenic MicroRNA Hsa-miR-155-5p targets the transcription factor ELK3 and links it to the hypoxia response. PLoS ONE. 2014;9:e113050 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠
  • 免疫印迹; 小鼠
Dong Y, Ito T, Velayo C, Sato T, Iida K, Endo M, et al. Intrauterine ischemic reperfusion switches the fetal transcriptional pattern from HIF-1α- to P53-dependent regulation in the murine brain. PLoS ONE. 2014;9:e110577 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • 免疫沉淀; 人类
  • 免疫印迹; 人类
Li B, Qiu B, Lee D, Walton Z, Ochocki J, Mathew L, et al. Fructose-1,6-bisphosphatase opposes renal carcinoma progression. Nature. 2014;513:251-5 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠
Neary M, Ng K, Ludtmann M, Hall A, Piotrowska I, Ong S, et al. Hypoxia signaling controls postnatal changes in cardiac mitochondrial morphology and function. J Mol Cell Cardiol. 2014;74:340-52 pubmed 出版商
  • 免疫印迹; 小鼠
Wang C, Cai Y, Zhang Y, Xiong Z, Li G, Cui L. Local injection of deferoxamine improves neovascularization in ischemic diabetic random flap by increasing HIF-1? and VEGF expression. PLoS ONE. 2014;9:e100818 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Zecchini V, Madhu B, Russell R, Pértega Gomes N, Warren A, Gaude E, et al. Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer. EMBO J. 2014;33:1365-82 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Inoue T, Kohro T, Tanaka T, Kanki Y, Li G, Poh H, et al. Cross-enhancement of ANGPTL4 transcription by HIF1 alpha and PPAR beta/delta is the result of the conformational proximity of two response elements. Genome Biol. 2014;15:R63 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Prasad P, Gordijo C, Abbasi A, Maeda A, Ip A, Rauth A, et al. Multifunctional albumin-MnO? nanoparticles modulate solid tumor microenvironment by attenuating hypoxia, acidosis, vascular endothelial growth factor and enhance radiation response. ACS Nano. 2014;8:3202-12 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • 免疫印迹; 人类
Li G, Ci W, Karmakar S, Chen K, Dhar R, Fan Z, et al. SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer. Cancer Cell. 2014;25:455-68 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
  • 免疫印迹; 小鼠
Fahrenbach J, Stoller D, Kim G, Aggarwal N, Yerokun B, Earley J, et al. Abcc9 is required for the transition to oxidative metabolism in the newborn heart. FASEB J. 2014;28:2804-15 pubmed 出版商
  • 免疫印迹; 小鼠
Guo X, Dason E, Zanon Moreno V, Jiang Q, Nahirnyj A, Chan D, et al. PGC-1? signaling coordinates susceptibility to metabolic and oxidative injury in the inner retina. Am J Pathol. 2014;184:1017-1029 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠
  • 免疫组化-石蜡切片; 小鼠
Takeda K, Duan L, Takeda H, Fong G. Improved vascular survival and growth in the mouse model of hindlimb ischemia by a remote signaling mechanism. Am J Pathol. 2014;184:686-96 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Glover L, Bowers B, Saeedi B, Ehrentraut S, Campbell E, Bayless A, et al. Control of creatine metabolism by HIF is an endogenous mechanism of barrier regulation in colitis. Proc Natl Acad Sci U S A. 2013;110:19820-5 pubmed 出版商
  • 免疫组化; 狗
  • 免疫印迹; 狗
Papa P, Sousa L, Silva R, de Fátima L, da Fonseca V, do Amaral V, et al. Glucose transporter 1 expression accompanies hypoxia sensing in the cyclic canine corpus luteum. Reproduction. 2014;147:81-9 pubmed 出版商
  • 免疫印迹; 人类
Tadokoro H, Umezu T, Ohyashiki K, Hirano T, Ohyashiki J. Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells. J Biol Chem. 2013;288:34343-51 pubmed 出版商
  • 免疫印迹; 人类
Kanematsu S, Tanimoto K, Suzuki Y, Sugano S. Screening for possible miRNA-mRNA associations in a colon cancer cell line. Gene. 2014;533:520-31 pubmed 出版商
  • 免疫印迹; 人类
Regan Anderson T, Peacock D, Daniel A, Hubbard G, Lofgren K, Girard B, et al. Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression. Cancer Res. 2013;73:5810-20 pubmed 出版商
  • 免疫印迹; 人类
Sena J, Wang L, Hu C. BRG1 and BRM chromatin-remodeling complexes regulate the hypoxia response by acting as coactivators for a subset of hypoxia-inducible transcription factor target genes. Mol Cell Biol. 2013;33:3849-63 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • 免疫细胞化学; 人类
Carbajo Pescador S, Ordonez R, Benet M, Jover R, García Palomo A, Mauriz J, et al. Inhibition of VEGF expression through blockade of Hif1? and STAT3 signalling mediates the anti-angiogenic effect of melatonin in HepG2 liver cancer cells. Br J Cancer. 2013;109:83-91 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Pawlus M, Wang L, Hu C. STAT3 and HIF1? cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cells. Oncogene. 2014;33:1670-9 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Shoji K, Murayama T, Mimura I, Wada T, Kume H, Goto A, et al. Sperm-associated antigen 4, a novel hypoxia-inducible factor 1 target, regulates cytokinesis, and its expression correlates with the prognosis of renal cell carcinoma. Am J Pathol. 2013;182:2191-203 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Chu X, Gao X, Jansson L, Quach M, Skogseid B, Barbu A. Multiple microvascular alterations in pancreatic islets and neuroendocrine tumors of a Men1 mouse model. Am J Pathol. 2013;182:2355-67 pubmed 出版商
  • 免疫细胞化学; 人类
Ganapathy S, Xiao S, Seo S, Lall R, Yang M, Xu T, et al. Low-dose arsenic induces chemotherapy protection via p53/NF-?B-mediated metabolic regulation. Oncogene. 2014;33:1359-66 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Kelly C, Glover L, Campbell E, Kominsky D, Ehrentraut S, Bowers B, et al. Fundamental role for HIF-1? in constitutive expression of human ? defensin-1. Mucosal Immunol. 2013;6:1110-8 pubmed 出版商
  • 免疫印迹; 人类
Bett J, Ibrahim A, Garg A, Kelly V, Pedrioli P, Rocha S, et al. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. Biochem J. 2013;451:185-94 pubmed 出版商
  • 免疫组化; 人类
Yao W, Li J, Wang J, Zhou W, Wang Q, Zhu R, et al. Effects of dietary ratio of n-6 to n-3 polyunsaturated fatty acids on immunoglobulins, cytokines, fatty acid composition, and performance of lactating sows and suckling piglets. J Anim Sci Biotechnol. 2012;3:43 pubmed 出版商
  • 免疫组化; 人类
Enzmann G, Mysiorek C, Gorina R, Cheng Y, Ghavampour S, Hannocks M, et al. The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury. Acta Neuropathol. 2013;125:395-412 pubmed 出版商
  • 免疫印迹; 小鼠
Forristal C, Winkler I, Nowlan B, Barbier V, Walkinshaw G, Levesque J. Pharmacologic stabilization of HIF-1? increases hematopoietic stem cell quiescence in vivo and accelerates blood recovery after severe irradiation. Blood. 2013;121:759-69 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • 免疫印迹; 人类
Chiang C, Nangaku M, Tanaka T, Iwawaki T, Inagi R. Endoplasmic reticulum stress signal impairs erythropoietin production: a role for ATF4. Am J Physiol Cell Physiol. 2013;304:C342-53 pubmed 出版商
  • 免疫印迹; 大鼠
Yue Y, Zhang P, Liu D, Yang J, Nie C, Yang D. Hypoxia preconditioning enhances the viability of ADSCs to increase the survival rate of ischemic skin flaps in rats. Aesthetic Plast Surg. 2013;37:159-70 pubmed 出版商
  • 免疫组化; 人类
  • 免疫印迹; 人类
Hernandez Luna M, Rocha Zavaleta L, Vega M, Huerta Yepez S. Hypoxia inducible factor-1α induces chemoresistance phenotype in non-Hodgkin lymphoma cell line via up-regulation of Bcl-xL. Leuk Lymphoma. 2013;54:1048-55 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Clambey E, McNamee E, Westrich J, Glover L, Campbell E, Jedlicka P, et al. Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa. Proc Natl Acad Sci U S A. 2012;109:E2784-93 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Pawlus M, Wang L, Ware K, Hu C. Upstream stimulatory factor 2 and hypoxia-inducible factor 2? (HIF2?) cooperatively activate HIF2 target genes during hypoxia. Mol Cell Biol. 2012;32:4595-610 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Aguado Fraile E, Ramos E, Sáenz Morales D, Conde E, Blanco Sánchez I, Stamatakis K, et al. miR-127 protects proximal tubule cells against ischemia/reperfusion: identification of kinesin family member 3B as miR-127 target. PLoS ONE. 2012;7:e44305 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Morote García J, Napiwotzky D, Kohler D, Rosenberger P. Endothelial Semaphorin 7A promotes neutrophil migration during hypoxia. Proc Natl Acad Sci U S A. 2012;109:14146-51 pubmed 出版商
  • 免疫组化; 人类
  • 免疫印迹; 人类
Tuomela J, Sandholm J, Karihtala P, Ilvesaro J, Vuopala K, Kauppila J, et al. Low TLR9 expression defines an aggressive subtype of triple-negative breast cancer. Breast Cancer Res Treat. 2012;135:481-93 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • 免疫印迹; 人类
Mimura I, Nangaku M, Kanki Y, Tsutsumi S, Inoue T, Kohro T, et al. Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A. Mol Cell Biol. 2012;32:3018-32 pubmed 出版商
  • 免疫组化; 小鼠
  • 免疫印迹; 小鼠
Rennie M, Detmar J, Whiteley K, Jurisicova A, Adamson S, Sled J. Expansion of the fetoplacental vasculature in late gestation is strain dependent in mice. Am J Physiol Heart Circ Physiol. 2012;302:H1261-73 pubmed 出版商
  • 免疫印迹; 大鼠
Anderson S, Oyama T, Lindsley J, Schutzer W, Beard D, Gattone V, et al. 2-Hydroxyestradiol slows progression of experimental polycystic kidney disease. Am J Physiol Renal Physiol. 2012;302:F636-45 pubmed 出版商
  • 免疫印迹; 小鼠
Edrey Y, Casper D, Huchon D, Mele J, Gelfond J, Kristan D, et al. Sustained high levels of neuregulin-1 in the longest-lived rodents; a key determinant of rodent longevity. Aging Cell. 2012;11:213-22 pubmed 出版商
  • 免疫沉淀; 人类
Erman A, Wabitsch M, Goodyer C. Human growth hormone receptor (GHR) expression in obesity: II. Regulation of the human GHR gene by obesity-related factors. Int J Obes (Lond). 2011;35:1520-9 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠
  • 免疫细胞化学; 大鼠
  • 免疫组化; 大鼠
  • 免疫印迹; 大鼠
  • 免疫组化-冰冻切片; 小鼠
  • 免疫细胞化学; 小鼠
  • 免疫组化; 小鼠
  • 免疫印迹; 小鼠
Belibi F, Zafar I, Ravichandran K, Segvic A, Jani A, Ljubanovic D, et al. Hypoxia-inducible factor-1? (HIF-1?) and autophagy in polycystic kidney disease (PKD). Am J Physiol Renal Physiol. 2011;300:F1235-43 pubmed 出版商
  • 免疫组化; 小鼠
Gubin M, Calaluce R, Davis J, Magee J, Strouse C, Shaw D, et al. Overexpression of the RNA binding protein HuR impairs tumor growth in triple negative breast cancer associated with deficient angiogenesis. Cell Cycle. 2010;9:3337-46 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠
Dikow R, Schmidt U, Kihm L, Schaier M, Schwenger V, Gross M, et al. Uremia aggravates left ventricular remodeling after myocardial infarction. Am J Nephrol. 2010;32:13-22 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
  • 免疫组化; 人类
Filby C, Hooper S, Wallace M. Partial pulmonary embolization disrupts alveolarization in fetal sheep. Respir Res. 2010;11:42 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Xia X, Kung A. Preferential binding of HIF-1 to transcriptionally active loci determines cell-type specific response to hypoxia. Genome Biol. 2009;10:R113 pubmed 出版商
  • 免疫细胞化学; 大鼠
Rane S, He M, Sayed D, Vashistha H, Malhotra A, Sadoshima J, et al. Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes. Circ Res. 2009;104:879-86 pubmed 出版商
  • 免疫印迹; 大鼠
Naito Y, Tsujino T, Matsumoto M, Sakoda T, Ohyanagi M, Masuyama T. Adaptive response of the heart to long-term anemia induced by iron deficiency. Am J Physiol Heart Circ Physiol. 2009;296:H585-93 pubmed 出版商
Takahashi N, Davy P, Gardner L, Mathews J, Yamazaki Y, Allsopp R. Hypoxia Inducible Factor 1 Alpha Is Expressed in Germ Cells throughout the Murine Life Cycle. PLoS ONE. 2016;11:e0154309 pubmed 出版商
Joyal J, Sun Y, Gantner M, Shao Z, Evans L, Saba N, et al. Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1. Nat Med. 2016;22:439-45 pubmed 出版商
Wang J, Ding N, Li Y, Cheng H, Wang D, Yang Q, et al. Insulin-like growth factor binding protein 5 (IGFBP5) functions as a tumor suppressor in human melanoma cells. Oncotarget. 2015;6:20636-49 pubmed
Oestreich K, Read K, Gilbertson S, Hough K, McDonald P, Krishnamoorthy V, et al. Bcl-6 directly represses the gene program of the glycolysis pathway. Nat Immunol. 2014;15:957-64 pubmed 出版商
Li X, Liu X, Xu Y, Liu J, Xie M, Ni W, et al. KLF5 promotes hypoxia-induced survival and inhibits apoptosis in non-small cell lung cancer cells via HIF-1?. Int J Oncol. 2014;45:1507-14 pubmed 出版商
Obama T, Takayanagi T, Kobayashi T, Bourne A, Elliott K, Charbonneau M, et al. Vascular induction of a disintegrin and metalloprotease 17 by angiotensin II through hypoxia inducible factor 1?. Am J Hypertens. 2015;28:10-4 pubmed 出版商
Eftedal I, Jørgensen A, Røsbjørgen R, Flatberg A, Brubakk A. Early genetic responses in rat vascular tissue after simulated diving. Physiol Genomics. 2012;44:1201-7 pubmed 出版商
Vakili H, Jin Y, Cattini P. Negative regulation of human growth hormone gene expression by insulin is dependent on hypoxia-inducible factor binding in primary non-tumor pituitary cells. J Biol Chem. 2012;287:33282-92 pubmed
Copple B, Kaska S, Wentling C. Hypoxia-inducible factor activation in myeloid cells contributes to the development of liver fibrosis in cholestatic mice. J Pharmacol Exp Ther. 2012;341:307-16 pubmed 出版商
Tanimoto K, Tsuchihara K, Kanai A, Arauchi T, Esumi H, Suzuki Y, et al. Genome-wide identification and annotation of HIF-1? binding sites in two cell lines using massively parallel sequencing. Hugo J. 2010;4:35-48 pubmed 出版商
Ravichandran K, Tyagi A, Deep G, Agarwal C, Agarwal R. Interleukin-1beta-induced iNOS expression in human lung carcinoma A549 cells: involvement of STAT and MAPK pathways. Indian J Exp Biol. 2011;49:840-7 pubmed
Bansal A, Harris R, DeGrado T. Choline phosphorylation and regulation of transcription of choline kinase ? in hypoxia. J Lipid Res. 2012;53:149-57 pubmed 出版商
Farrow E, Yu X, Summers L, Davis S, Fleet J, Allen M, et al. Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice. Proc Natl Acad Sci U S A. 2011;108:E1146-55 pubmed 出版商
Wang Y, Huang J, Li M, Cavenee W, Mitchell P, Zhou X, et al. MicroRNA-138 modulates DNA damage response by repressing histone H2AX expression. Mol Cancer Res. 2011;9:1100-11 pubmed 出版商
Lee S, Kim H, Jin Y, Choi A, Ryter S. Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis. Autophagy. 2011;7:829-39 pubmed
Raina S, Honer M, Krämer S, Liu Y, Wang X, Segerer S, et al. Anti-VEGF antibody treatment accelerates polycystic kidney disease. Am J Physiol Renal Physiol. 2011;301:F773-83 pubmed 出版商
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产品信息
SKU号 :
NB100-134
产品名称 :
HIF-1甲抗体
规格 :
0.1毫升
描述 :
The HIF-1 alpha Antibody from Novus is a rabbit polyclonal antibody to HIF-1 alpha. This antibody reacts with human, mouse, rat, canine, guinea pig, primate, xenopus, zebrafish. The HIF-1 alpha Antibody has been validated for the following applications: Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Gel Super Shift Assays, Knockout Validated.
靶标 :
HIF-1甲
类别 :
一抗
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
A fusion protein made to an internal sequence of human HIF-1 alpha (containing amino acids 432 - 528) [UniProt Q16665].
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种活性 :
人类, 小鼠, 大鼠, 狗, 豚鼠, 灵长类动物, 蛙, 斑马鱼
Theoretical Molecular Weight :
93 kDa
基因符号 :
缺氧诱导因子1A
AccessionNumbers :
Q61221, O35800
应用 :
Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Gel Super Shift Assays, Knockout Validated
价格 :
349美元
又名 :
ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, BHLHE78, Class E basic helix-loop-helix protein 78, HIF-1 alpha, HIF1A, HIF-1-alpha, HIF1-alpha, hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), hypoxia-inducible factor 1-alpha, Member of PAS protein 1, member of PAS superfamily 1, MOP1HIF1-ALPHA, PAS domain-containing protein 8, PASD8alpha subunit (basic helix-loop-helix transcription factor)
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。