产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
HIF-1 alpha Antibody - BSA Free
目录 :
NB100-134
规格 :
0.1 ml (also 0.025 ml)
价格 :
449美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, , , 斑马鱼
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 111
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 小鼠; 图 6b
Shao R, Zhang Z, Xu Z, Ouyang H, Wang L, Ouyang H, et al. H3K36 methyltransferase NSD1 regulates chondrocyte differentiation for skeletal development and fracture repair. Bone Res. 2021;9:30 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:150; 图 5e
  • 免疫组化-石蜡切片; 小鼠; 1:150; 图 5a, 7a
Turgu B, Zhang F, El Naggar A, Negri G, Kogler M, Tortola L, et al. HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner. Oncogene. 2021;40:1988-2001 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 8e
Devraj G, Guérit S, Seele J, Spitzer D, Macas J, Khel M, et al. HIF-1α is involved in blood-brain barrier dysfunction and paracellular migration of bacteria in pneumococcal meningitis. Acta Neuropathol. 2020;140:183-208 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 5a
Dmitrieva N, Walts A, Nguyen D, Grubb A, Zhang X, Wang X, et al. Impaired angiogenesis and extracellular matrix metabolism in autosomal-dominant hyper-IgE syndrome. J Clin Invest. 2020;130:4167-4181 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4b
Cheng Y, Sun M, Chen L, Li Y, Lin L, Yao B, et al. Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice. Cell Rep. 2018;25:3194-3203.e4 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 s4e
Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al. AMP kinase promotes glioblastoma bioenergetics and tumour growth. Nat Cell Biol. 2018;20:823-835 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 3a
Yuan X, Qi H, Li X, Wu F, Fang J, Bober E, et al. Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice. J Clin Invest. 2017;127:2235-2248 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Murakami A, Wang L, Kalhorn S, Schraml P, Rathmell W, Tan A, et al. Context-dependent role for chromatin remodeling component PBRM1/BAF180 in clear cell renal cell carcinoma. Oncogenesis. 2017;6:e287 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 4f
Salvi V, Vermi W, Gianello V, Lonardi S, Gagliostro V, Naldini A, et al. Dendritic cell-derived VEGF-A plays a role in inflammatory angiogenesis of human secondary lymphoid organs and is driven by the coordinated activation of multiple transcription factors. Oncotarget. 2016;7:39256-39269 pubmed 出版商
  • 免疫组化-石蜡切片; 犬; 1:500; 图 5
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  • 染色质免疫沉淀 ; 小鼠
Semba H, Takeda N, Isagawa T, Sugiura Y, Honda K, Wake M, et al. HIF-1?-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity. Nat Commun. 2016;7:11635 pubmed 出版商
  • 免疫印迹; 人类; 图 3
  • 免疫印迹基因敲除验证; 小鼠; 图 3
Mori H, Yao Y, Learman B, Kurozumi K, Ishida J, Ramakrishnan S, et al. Induction of WNT11 by hypoxia and hypoxia-inducible factor-1α regulates cell proliferation, migration and invasion. Sci Rep. 2016;6:21520 pubmed 出版商
  • 免疫沉淀; 人类; 1:200; 图 2f
  • 免疫印迹; 人类; 1:1000; 图 2f
Lin A, Li C, Xing Z, Hu Q, Liang K, Han L, et al. The LINK-A lncRNA activates normoxic HIF1? signalling in triple-negative breast cancer. Nat Cell Biol. 2016;18:213-24 pubmed 出版商
  • 免疫印迹; 人类; 图 1
de Jong O, van Balkom B, Gremmels H, Verhaar M. Exosomes from hypoxic endothelial cells have increased collagen crosslinking activity through up-regulation of lysyl oxidase-like 2. J Cell Mol Med. 2016;20:342-50 pubmed 出版商
  • 免疫印迹; 大鼠
  • 免疫印迹; 小鼠; 1:600
Hung Y, Chang S, Huang C, Yin J, Hwang C, Yang L, et al. Inhibitor of Differentiation-1 and Hypoxia-Inducible Factor-1 Mediate Sonic Hedgehog Induction by Amyloid Beta-Peptide in Rat Cortical Neurons. Mol Neurobiol. 2016;53:793-809 pubmed 出版商
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Kishimoto H, Nakano T, Torisu K, Tokumoto M, Uchida Y, Yamada S, et al. Indoxyl sulfate induces left ventricular hypertrophy via the AhR-FGF23-FGFR4 signaling pathway. Front Cardiovasc Med. 2023;10:990422 pubmed 出版商
Lee E, Lee E, Kong E, Chon H, Llaiqui Condori M, Park C, et al. An agonistic anti-Tie2 antibody suppresses the normal-to-tumor vascular transition in the glioblastoma invasion zone. Exp Mol Med. 2023;55:470-484 pubmed 出版商
Barone F, Urb xe9 S, Clague M. Segregation of pathways leading to pexophagy. Life Sci Alliance. 2023;6: pubmed 出版商
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E G, Sun B, Liu B, Xu G, He S, Wang Y, et al. Enhanced BPGM/2,3-DPG pathway activity suppresses glycolysis in hypoxic astrocytes via FIH-1 and TET2. Brain Res Bull. 2023;192:36-46 pubmed 出版商
Do T, Lau J, Sun C, Liu S, Kha K, Lim S, et al. Hypoxia deactivates epigenetic feedbacks via enzyme-derived clicking proteolysis-targeting chimeras. Sci Adv. 2022;8:eabq2216 pubmed 出版商
La Salvia A, Carletti R, Verrico M, Feola T, Puliani G, Bassi M, et al. Angioside: The role of Angiogenesis and Hypoxia in Lung Neuroendocrine Tumours According to Primary Tumour Location in Left or Right Parenchyma. J Clin Med. 2022;11: pubmed 出版商
Tikhonova M, Maslov N, Bashirzade A, Nehoroshev E, Babchenko V, Chizhova N, et al. A Novel Laser-Based Zebrafish Model for Studying Traumatic Brain Injury and Its Molecular Targets. Pharmaceutics. 2022;14: pubmed 出版商
Li X, Wang L, Qin X, Chen X, Li L, Huang Z, et al. Estrogens revert neutrophil hyperplasia by inhibiting Hif1α-cMyb pathway in zebrafish myelodysplastic syndromes models. Cell Death Discov. 2022;8:323 pubmed 出版商
Suresh M, Yalamanchili G, Rao T, Aktay S, Kralovich A, Shah Y, et al. Hypoxia-inducible factor (HIF)-1α-induced regulation of lung injury in pulmonary aspiration is mediated through NF-kB. FASEB Bioadv. 2022;4:309-328 pubmed 出版商
Vianello C, Cocetta V, Catanzaro D, Dorn G, De Milito A, Rizzolio F, et al. Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy. Cell Death Dis. 2022;13:398 pubmed 出版商
Cristancho A, Gadra E, Samba I, Zhao C, Ouyang M, Magnitsky S, et al. Deficits in Seizure Threshold and Other Behaviors in Adult Mice without Gross Neuroanatomic Injury after Late Gestation Transient Prenatal Hypoxia. Dev Neurosci. 2022;44:246-265 pubmed 出版商
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Moberg M, Apr xf3 W, Horwath O, van Hall G, Blackwood S, Katz A. Acute normobaric hypoxia blunts contraction-mediated mTORC1- and JNK-signaling in human skeletal muscle. Acta Physiol (Oxf). 2022;234:e13771 pubmed 出版商
Lefort S, El Naggar A, Tan S, Colborne S, Negri G, Pellacani D, et al. De novo and cell line models of human mammary cell transformation reveal an essential role for Yb-1 in multiple stages of human breast cancer. Cell Death Differ. 2021;: pubmed 出版商
Li W, Duan A, Xing Y, Xu L, Yang J. Transcription-Based Multidimensional Regulation of Fatty Acid Metabolism by HIF1α in Renal Tubules. Front Cell Dev Biol. 2021;9:690079 pubmed 出版商
Siddiqui F, Vukic V, Salminen T, Abankwa D. Elaiophylin Is a Potent Hsp90/ Cdc37 Protein Interface Inhibitor with K-Ras Nanocluster Selectivity. Biomolecules. 2021;11: pubmed 出版商
Lopez Ramirez M, Lai C, Soliman S, Hale P, Pham A, Estrada E, et al. Astrocytes propel neurovascular dysfunction during cerebral cavernous malformation lesion formation. J Clin Invest. 2021;131: pubmed 出版商
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Andrysik Z, Bender H, Galbraith M, Espinosa J. Multi-omics analysis reveals contextual tumor suppressive and oncogenic gene modules within the acute hypoxic response. Nat Commun. 2021;12:1375 pubmed 出版商
Perrin Cocon L, Vidalain P, Jacquemin C, Aublin Gex A, Olmstead K, Panthu B, et al. A hexokinase isoenzyme switch in human liver cancer cells promotes lipogenesis and enhances innate immunity. Commun Biol. 2021;4:217 pubmed 出版商
Schaff D, Singh S, Kim K, Sutcliffe M, Park K, Janes K. Fragmentation of Small-cell Lung Cancer Regulatory States in Heterotypic Microenvironments. Cancer Res. 2021;: pubmed 出版商
Cheng Y, Chiang H, Cheng S, Chang H, Li Y, Shieh S. Loss of the tumor suppressor BTG3 drives a pro-angiogenic tumor microenvironment through HIF-1 activation. Cell Death Dis. 2020;11:1046 pubmed 出版商
Carrasco Pozo C, Tan K, Avery V. Hemin Prevents Increased Glycolysis in Macrophages upon Activation: Protection by Microbiota-Derived Metabolites of Polyphenols. Antioxidants (Basel). 2020;9: pubmed 出版商
Turhan A, Pereira M, Schuler G, Bleul U, Kowalewski M. Hypoxia-inducible factor (HIF1alpha) inhibition modulates cumulus cell function and affects bovine oocyte maturation in vitro. Biol Reprod. 2020;: pubmed 出版商
Dey A, Prabhudesai S, Zhang Y, Rao G, Thirugnanam K, Hossen M, et al. Cystathione β-synthase regulates HIF-1α stability through persulfidation of PHD2. Sci Adv. 2020;6: pubmed 出版商
Yang W, Yu T, Huang X, Bilotta A, Xu L, Lu Y, et al. Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity. Nat Commun. 2020;11:4457 pubmed 出版商
Dowdell A, Cartwright I, Goldberg M, Kostelecky R, Ross T, Welch N, et al. The HIF target ATG9A is essential for epithelial barrier function and tight junction biogenesis. Mol Biol Cell. 2020;31:2249-2258 pubmed 出版商
Cohrs G, Drucks B, Synowitz M, Held Feindt J, Knerlich Lukoschus F. Expression Patterns of Hypoxia-Inducible Factors, Proinflammatory, and Neuroprotective Cytokines in Neuroepithelial Tissues of Lumbar Spinal Lipomas-A Pilot Study. World Neurosurg. 2020;141:e633-e644 pubmed 出版商
James N, Emerson J, Borgstadt A, Beffa L, Oliver M, Hovanesian V, et al. The biomarker HE4 (WFDC2) promotes a pro-angiogenic and immunosuppressive tumor microenvironment via regulation of STAT3 target genes. Sci Rep. 2020;10:8558 pubmed 出版商
Ménégaut L, Thomas C, Jalil A, Julla J, Magnani C, Ceroi A, et al. Interplay between Liver X Receptor and Hypoxia Inducible Factor 1α Potentiates Interleukin-1β Production in Human Macrophages. Cell Rep. 2020;31:107665 pubmed 出版商
Peng W, de Bruijn H, ten Hagen T, van Dam G, Roodenburg J, Berg K, et al. Targeted Photodynamic Therapy of Human Head and Neck Squamous Cell Carcinoma with Anti-epidermal Growth Factor Receptor Antibody Cetuximab and Photosensitizer IR700DX in the Mouse Skin-fold Window Chamber Model. Photochem Photobiol. 2020;96:708-717 pubmed 出版商
Liu L, Zhang L, Zhao J, Guo X, Luo Y, Hu W, et al. Tumor Necrosis Factor Receptor-Associated Protein 1 Protects against Mitochondrial Injury by Preventing High Glucose-Induced mPTP Opening in Diabetes. Oxid Med Cell Longev. 2020;2020:6431517 pubmed 出版商
Lucia K, Wu Y, Garcia J, Barlier A, Buchfelder M, Saeger W, et al. Hypoxia and the hypoxia inducible factor 1α activate protein kinase A by repressing RII beta subunit transcription. Oncogene. 2020;39:3367-3380 pubmed 出版商
Sorkin M, Huber A, HWANG C, Carson W, Menon R, Li J, et al. Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing. Nat Commun. 2020;11:722 pubmed 出版商
Wierenga A, Cunningham A, Erdem A, Lopera N, Brouwers Vos A, Pruis M, et al. HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cells. Cancer Metab. 2019;7:11 pubmed 出版商
Andrade F, Nguyen N, Warri A, Hilakivi Clarke L. Reversal of increased mammary tumorigenesis by valproic acid and hydralazine in offspring of dams fed high fat diet during pregnancy. Sci Rep. 2019;9:20271 pubmed 出版商
Chao A, Chen C, Wu M, Hou B, Yang D. Roles of Id1/HIF-1 and CDK5/HIF-1 in cell cycle reentry induced by amyloid-beta peptide in post-mitotic cortical neuron. Biochim Biophys Acta Mol Cell Res. 2020;1867:118628 pubmed 出版商
Zhao L, Zhao J, Gao R, Tian Y, Zhang Y, Tang W, et al. Intrabody against prolyl hydroxylase 2 ameliorates acetaminophen-induced acute liver injury in mice via concomitant promotion of angiogenesis and redox homeostasis. Biomed Pharmacother. 2020;123:109783 pubmed 出版商
Han H, Jain A, Truica M, Izquierdo Ferrer J, Anker J, Lysy B, et al. Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy. Cancer Cell. 2019;36:483-497.e15 pubmed 出版商
Carrasco Pozo C, Tan K, Rodriguez T, Avery V. The Molecular Effects of Sulforaphane and Capsaicin on Metabolism upon Androgen and Tip60 Activation of Androgen Receptor. Int J Mol Sci. 2019;20: pubmed 出版商
Osawa T, Shimamura T, Saito K, Hasegawa Y, Ishii N, Nishida M, et al. Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2. Cell Rep. 2019;29:89-103.e7 pubmed 出版商
Zhao L, Liu Z, Yang F, Zhang Y, Xue Y, Miao H, et al. Intrabody against prolyl hydroxylase 2 promotes angiogenesis by stabilizing hypoxia-inducible factor-1α. Sci Rep. 2019;9:11861 pubmed 出版商
Oyama Y, Bartman C, Bonney S, Lee J, Walker L, Han J, et al. Intense Light-Mediated Circadian Cardioprotection via Transcriptional Reprogramming of the Endothelium. Cell Rep. 2019;28:1471-1484.e11 pubmed 出版商
Mallikarjuna P, Raviprakash T, Aripaka K, Ljungberg B, Landström M. Interactions between TGF-β type I receptor and hypoxia-inducible factor-α mediates a synergistic crosstalk leading to poor prognosis for patients with clear cell renal cell carcinoma. Cell Cycle. 2019;18:2141-2156 pubmed 出版商
Masterson J, Biette K, Hammer J, Nguyen N, Capocelli K, Saeedi B, et al. Epithelial HIF-1α/claudin-1 axis regulates barrier dysfunction in eosinophilic esophagitis. J Clin Invest. 2019;129:3224-3235 pubmed 出版商
Abe H, Takeda N, Isagawa T, Semba H, Nishimura S, Morioka M, et al. Macrophage hypoxia signaling regulates cardiac fibrosis via Oncostatin M. Nat Commun. 2019;10:2824 pubmed 出版商
Locri F, Dal Monte M, Aronsson M, Cammalleri M, De Rosa M, Pavone V, et al. UPARANT is an effective antiangiogenic agent in a mouse model of rubeosis iridis. J Mol Med (Berl). 2019;97:1273-1283 pubmed 出版商
Kaushik D, Bhattacharya A, Mirzaei R, Rawji K, Ahn Y, Rho J, et al. Enhanced glycolytic metabolism supports transmigration of brain-infiltrating macrophages in multiple sclerosis. J Clin Invest. 2019;129:3277-3292 pubmed 出版商
Yang Y, Li M, Xu G, Feng L, Zhang E, Chen J, et al. Nogo-B Receptor Directs Mitochondria-Associated Membranes to Regulate Vascular Smooth Muscle Cell Proliferation. Int J Mol Sci. 2019;20: pubmed 出版商
Tumova S, Kerimi A, Williamson G. Long term treatment with quercetin in contrast to the sulfate and glucuronide conjugates affects HIF1α stability and Nrf2 signaling in endothelial cells and leads to changes in glucose metabolism. Free Radic Biol Med. 2019;137:158-168 pubmed 出版商
Harms M, Li Q, Lee S, Zhang C, Kull B, Hallen S, et al. Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes. Cell Rep. 2019;27:213-225.e5 pubmed 出版商
Fu H, Ding X, Zhang W, Kang Y. Profiling of nuclear copper-binding proteins under hypoxic condition. Biometals. 2019;32:329-341 pubmed 出版商
Wu Z, Zhang W, Kang Y. Copper affects the binding of HIF-1α to the critical motifs of its target genes. Metallomics. 2019;11:429-438 pubmed 出版商
Lambertini E, Penolazzi L, Angelozzi M, Bergamin L, Manferdini C, Vieceli Dalla Sega F, et al. Hypoxia Preconditioning of Human MSCs: a Direct Evidence of HIF-1α and Collagen Type XV Correlation. Cell Physiol Biochem. 2018;51:2237-2249 pubmed 出版商
Fuhrmann D, Wittig I, Brüne B. TMEM126B deficiency reduces mitochondrial SDH oxidation by LPS, attenuating HIF-1α stabilization and IL-1β expression. Redox Biol. 2019;20:204-216 pubmed 出版商
Yang L, Chen M, Zhang J, Ren D, Hu B. Hypoxia Delays Oligodendrocyte Progenitor Cell Migration and Myelin Formation by Suppressing Bmp2b Signaling in Larval Zebrafish. Front Cell Neurosci. 2018;12:348 pubmed 出版商
Cohrs G, Drucks B, Sürie J, Vokuhl C, Synowitz M, Held Feindt J, et al. Expression profiles of pro-inflammatory and pro-apoptotic mediators in secondary tethered cord syndrome after myelomeningocele repair surgery. Childs Nerv Syst. 2019;35:315-328 pubmed 出版商
Stoyanoff T, Rodriguez J, Todaro J, Colavita J, Torres A, Aguirre M. Erythropoietin attenuates LPS-induced microvascular damage in a murine model of septic acute kidney injury. Biomed Pharmacother. 2018;107:1046-1055 pubmed 出版商
Ronellenfitsch M, Zeiner P, Mittelbronn M, Urban H, Pietsch T, Reuter D, et al. Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma. Acta Neuropathol Commun. 2018;6:81 pubmed 出版商
Zheng J, Zhang M, Weng H. Induction of the mitochondrial NDUFA4L2 protein by HIF-1a regulates heart regeneration by promoting the survival of cardiac stem cell. Biochem Biophys Res Commun. 2018;503:2226-2233 pubmed 出版商
Peruzzotti Jametti L, Bernstock J, Vicario N, Costa A, Kwok C, Leonardi T, et al. Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation. Cell Stem Cell. 2018;22:355-368.e13 pubmed 出版商
Dopeso H, Jiao H, Cuesta A, Henze A, Jurida L, Kracht M, et al. PHD3 Controls Lung Cancer Metastasis and Resistance to EGFR Inhibitors through TGFα. Cancer Res. 2018;78:1805-1819 pubmed 出版商
Eriksson J, Wanka C, Burger M, Urban H, Hartel I, von Renesse J, et al. Suppression of oxidative phosphorylation confers resistance against bevacizumab in experimental glioma. J Neurochem. 2017;: pubmed 出版商
McClendon J, Jansing N, Redente E, Gandjeva A, Ito Y, Colgan S, et al. Hypoxia-Inducible Factor 1? Signaling Promotes Repair of the Alveolar Epithelium after Acute Lung Injury. Am J Pathol. 2017;187:1772-1786 pubmed 出版商
Li D, Du Y, Yuan X, Han X, Dong Z, Chen X, et al. Hepatic hypoxia-inducible factors inhibit PPAR? expression to exacerbate acetaminophen induced oxidative stress and hepatotoxicity. Free Radic Biol Med. 2017;110:102-116 pubmed 出版商
Zhang X, Liu L, Liu J, Cheng Z, Wang Z, Shi C, et al. Endothelial cells co-cultured with renal carcinoma cells significantly reduce RECK expression under chemical hypoxia. Cell Biol Int. 2017;41:922-927 pubmed 出版商
Mimura I, Hirakawa Y, Kanki Y, Kushida N, Nakaki R, Suzuki Y, et al. Novel lnc RNA regulated by HIF-1 inhibits apoptotic cell death in the renal tubular epithelial cells under hypoxia. Physiol Rep. 2017;5: pubmed 出版商
Hou F, Li W, Shi Q, Li H, Liu S, Zong S, et al. Yi Ai Fang, a traditional Chinese herbal formula, impacts the vasculogenic mimicry formation of human colorectal cancer through HIF-1? and epithelial mesenchymal transition. BMC Complement Altern Med. 2016;16:428 pubmed
Soncini M, Corna G, Moresco M, Coltella N, Restuccia U, Maggioni D, et al. 24-Hydroxycholesterol participates in pancreatic neuroendocrine tumor development. Proc Natl Acad Sci U S A. 2016;113:E6219-E6227 pubmed
Kushida N, Nomura S, Mimura I, Fujita T, Yamamoto S, Nangaku M, et al. Hypoxia-Inducible Factor-1? Activates the Transforming Growth Factor-?/SMAD3 Pathway in Kidney Tubular Epithelial Cells. Am J Nephrol. 2016;44:276-285 pubmed
Campillo N, Jorba I, Schaedel L, Casals B, Gozal D, Farre R, et al. A Novel Chip for Cyclic Stretch and Intermittent Hypoxia Cell Exposures Mimicking Obstructive Sleep Apnea. Front Physiol. 2016;7:319 pubmed 出版商
Sullivan A, Peet D, Whitelaw M. MAGED1 is a novel regulator of a select subset of bHLH PAS transcription factors. FEBS J. 2016;283:3488-502 pubmed 出版商
Kowitzke B, Cohrs G, Leuschner I, Koch A, Synowitz M, Mehdorn H, et al. Cellular Profiles and Molecular Mediators of Lesion Cascades in the Placode in Human Open Spinal Neural Tube Defects. J Neuropathol Exp Neurol. 2016;75:827-42 pubmed 出版商
Hoang N, Kadonosono T, Kuchimaru T, Kizaka Kondoh S. Hypoxia-inducible factor-targeting prodrug TOP3 combined with gemcitabine or TS-1 improves pancreatic cancer survival in an orthotopic model. Cancer Sci. 2016;107:1151-8 pubmed 出版商
Mammadzada P, Gudmundsson J, Kvanta A, André H. Differential hypoxic response of human choroidal and retinal endothelial cells proposes tissue heterogeneity of ocular angiogenesis. Acta Ophthalmol. 2016;94:805-814 pubmed 出版商
Jang J, Ko M, Yun J, Kim M, Kim J, Park H, et al. Nitric Oxide Produced by Macrophages Inhibits Adipocyte Differentiation and Promotes Profibrogenic Responses in Preadipocytes to Induce Adipose Tissue Fibrosis. Diabetes. 2016;65:2516-28 pubmed 出版商
Takahashi N, Davy P, Gardner L, Mathews J, Yamazaki Y, Allsopp R. Hypoxia Inducible Factor 1 Alpha Is Expressed in Germ Cells throughout the Murine Life Cycle. PLoS ONE. 2016;11:e0154309 pubmed 出版商
Joyal J, Sun Y, Gantner M, Shao Z, Evans L, Saba N, et al. Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1. Nat Med. 2016;22:439-45 pubmed 出版商
Song M, Liu T, Shi C, Zhang X, Chen X. Bioconjugated Manganese Dioxide Nanoparticles Enhance Chemotherapy Response by Priming Tumor-Associated Macrophages toward M1-like Phenotype and Attenuating Tumor Hypoxia. ACS Nano. 2016;10:633-647 pubmed 出版商
Cheng S, Xing W, Pourteymoor S, Schulte J, Mohan S. Conditional Deletion of Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Gene Reveals Its Essential Role in Chondrocyte Function and Endochondral Bone Formation. Endocrinology. 2016;157:127-40 pubmed 出版商
Highet A, Khoda S, Buckberry S, Leemaqz S, Bianco Miotto T, Harrington E, et al. Hypoxia induced HIF-1/HIF-2 activity alters trophoblast transcriptional regulation and promotes invasion. Eur J Cell Biol. 2015;94:589-602 pubmed 出版商
André H, Tunik S, Aronsson M, Kvanta A. Hypoxia-Inducible Factor-1α Is Associated With Sprouting Angiogenesis in the Murine Laser-Induced Choroidal Neovascularization Model. Invest Ophthalmol Vis Sci. 2015;56:6591-604 pubmed 出版商
Chen P, Weng J, Hsu P, Shew J, Huang Y, Lee W. NPGPx modulates CPEB2-controlled HIF-1α RNA translation in response to oxidative stress. Nucleic Acids Res. 2015;43:9393-404 pubmed 出版商
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产品信息
品牌 :
Novus Biologicals, a Bio-Techne Brand
catalog number base :
NB100-134
SKU号 :
NB100-134
产品名称 :
HIF-1 alpha Antibody - BSA Free
描述 :
The HIF-1 alpha Antibody - BSA Free from Novus is a rabbit polyclonal antibody to HIF-1 alpha. This antibody reacts with human, mouse, rat, bovine, canine, guinea pig, primate, xenopus, zebrafish. The HIF-1 alpha Antibody - BSA Free has been validated for the following applications: Western Blot, Simple Western, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Gel Super Shift Assays, Chromatin Immunoprecipitation (ChIP), Knockout Validated, Chromatin Immunoprecipitation Sequencing, Dual RNAscope ISH-IHC.
靶标 :
HIF-1甲
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
This HIF-1 alpha Antibody was developed against a fusion protein made to an internal sequence of human HIF-1 alpha (containing amino acids 432 - 528) [Uniprot# Q16665].
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类, 小鼠, 大鼠, 牛, 狗, 豚鼠, 灵长类动物, 蛙, 斑马鱼
理论上的分子量 :
93 kDa
基因符号 :
缺氧诱导因子1A
accessionNumbers :
Q61221, O35800
应用 :
Western Blot, Simple Western, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Gel Super Shift Assays, Chromatin Immunoprecipitation (ChIP), Knockout Validated, Chromatin Immunoprecipitation Sequencing, Dual RNAscope ISH-IHC
美元 :
449美元
别名 :
AINT, anti-HIF-1 alpha, anti-HIF1A, ARNT interacting protein, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, BHLHE78, Class E basic helix-loop-helix protein 78, HIF1, HIF-1 alpha, HIF1A, HIF-1A, HIF-1alpha, HIF-1-alpha, HIF1-alpha, hypoxia inducible factor 1 alpha subunit, hypoxia inducible factor 1 subunit alpha, hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), hypoxia-inducible factor 1-alpha, Member of PAS protein 1, member of PAS superfamily 1, MOP1, PAS domain-containing protein 8, PASD8
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。