产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
Mre11抗体
目录 :
NB100-142
规格 :
0.05 ml (also 0.025 ml)
价格 :
399美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, proximity ligation assay
更多信息或购买 :
文章摘录数: 61
参考文献
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Mukherjee J, Pandita A, Kamalakar C, Johannessen T, Ohba S, Tang Y, et al. A subset of PARP inhibitors induces lethal telomere fusion in ALT-dependent tumor cells. Sci Transl Med. 2021;13: pubmed 出版商
Cabral J, Cushman C, Sodroski C, Knipe D. ATRX limits the accessibility of histone H3-occupied HSV genomes during lytic infection. PLoS Pathog. 2021;17:e1009567 pubmed 出版商
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Zou R, Liu Y, Wu B, Ha T. Cas9 deactivation with photocleavable guide RNAs. Mol Cell. 2021;81:1553-1565.e8 pubmed 出版商
Somyajit K, Spies J, Coscia F, Kirik U, Rask M, Lee J, et al. Homology-directed repair protects the replicating genome from metabolic assaults. Dev Cell. 2021;56:461-477.e7 pubmed 出版商
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Zhou Z, Kirtay M, Schneble N, Yakoub G, Ding M, Rüdiger T, et al. NBS1 interacts with Notch signaling in neuronal homeostasis. Nucleic Acids Res. 2020;48:10924-10939 pubmed 出版商
Lan W, Santofimia Castaño P, Swayden M, Xia Y, Zhou Z, Audebert S, et al. ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents. JCI Insight. 2020;5: pubmed 出版商
Volcic M, Sparrer K, Koepke L, Hotter D, Sauter D, Stürzel C, et al. Vpu modulates DNA repair to suppress innate sensing and hyper-integration of HIV-1. Nat Microbiol. 2020;5:1247-1261 pubmed 出版商
Herrmann C, Dybas J, Liddle J, Price A, Hayer K, Lauman R, et al. Adenovirus-mediated ubiquitination alters protein-RNA binding and aids viral RNA processing. Nat Microbiol. 2020;5:1217-1231 pubmed 出版商
Rainey M, Quinlan A, Cazzaniga C, Mijic S, Martella O, Krietsch J, et al. CDC7 kinase promotes MRE11 fork processing, modulating fork speed and chromosomal breakage. EMBO Rep. 2020;:e48920 pubmed 出版商
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Qi F, Meng Q, Hayashi I, Kobayashi J. FXR1 is a novel MRE11-binding partner and participates in oxidative stress responses. J Radiat Res. 2020;61:368-375 pubmed 出版商
Vancevska A, Ahmed W, Pfeiffer V, Feretzaki M, Boulton S, Lingner J. SMCHD1 promotes ATM-dependent DNA damage signaling and repair of uncapped telomeres. EMBO J. 2020;39:e102668 pubmed 出版商
Paiano J, Wu W, Yamada S, Sciascia N, Callen E, Paola Cotrim A, et al. ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis. Nat Commun. 2020;11:857 pubmed 出版商
Mladenov E, Staudt C, Soni A, Murmann Konda T, Siemann Loekes M, Iliakis G. Strong suppression of gene conversion with increasing DNA double-strand break load delimited by 53BP1 and RAD52. Nucleic Acids Res. 2020;48:1905-1924 pubmed 出版商
Fievet A, Bellanger D, Zahed L, Burglen L, Derrien A, Dubois d Enghien C, et al. DNA repair functional analyses of NBN hypomorphic variants associated with NBN-related infertility. Hum Mutat. 2020;41:608-618 pubmed 出版商
Pan X, Chen Y, Biju B, Ahmed N, Kong J, Goldenberg M, et al. FANCM suppresses DNA replication stress at ALT telomeres by disrupting TERRA R-loops. Sci Rep. 2019;9:19110 pubmed 出版商
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Bai Y, Wang W, Li S, Zhan J, Li H, Zhao M, et al. C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex. Mol Cell. 2019;: pubmed 出版商
Yoshimura Y. Increased error-free DNA repair gene expression through reprogramming in human iPS cells. Regen Ther. 2019;11:101-105 pubmed 出版商
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Zhou H, Kawamura K, Yanagihara H, Kobayashi J, Zhang Akiyama Q. NBS1 is regulated by two kind of mechanisms: ATM-dependent complex formation with MRE11 and RAD50, and cell cycle-dependent degradation of protein. J Radiat Res. 2017;58:487-494 pubmed 出版商
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图像
图像 1 :
Novus Biologicals NB100-142 图像 1
Simple Western: Mre11 Antibody [NB100-142] - Image shows a specific band for Mre11 in 0.5 mg/mL of HeLa lysate. A band appears at the theoretical molecular weight of 81 kDa for this product. This experiment was performed under reducing conditions using the 12-230 kDa separation system.
产品信息
品牌 :
Novus
MasterCode :
NB100-142
SKU号 :
NB100-142
产品名称 :
Mre11抗体
描述 :
The Mre11 Antibody from NB100-142 is a nb100-142 antibody to . This antibody reacts with breast cancer, cancer, cell cycle and replication, checkpoint signaling, chromatin research, dna double strand break repair, dna repair, homologous recombination, non homologous end joining, protein phosphatase. The Mre11 Antibody has been validated for the following applications: P49959.
靶标 :
Mre11
类别 :
一抗
单位尺寸 :
0.05 ml (also 0.025 ml)
缓冲液 :
Whole antisera
克隆性 :
多克隆
共轭标签 :
未共轭
宿主 :
免疫原 :
Mre11 Antibody is made to a full length human Mre11 protein. [Uniprot: P49959]
抗体亚型 :
IgG
纯度 :
Unpurified
物种 :
人类, 小鼠, 大鼠, 鸡, 仓鼠
理论上的分子量 :
81 kDa
基因符号 :
MRE11
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Mre11-Antibody-Simple-Western-NB100-142-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Mre11-Antibody-Simple-Western-NB100-142-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Mre11-Antibody-Immunocytochemistry-Immunofluorescence-NB100-142-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Mre11-Antibody-Immunocytochemistry-Immunofluorescence-NB100-142-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Mre11-Antibody-Knockdown-Validated-NB100-142-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Mre11-Antibody-Knockdown-Validated-NB100-142-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Mre11-Antibody-Immunohistochemistry-NB100-142-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Mre11-Antibody-Immunohistochemistry-NB100-142-img0004.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Mre11-Antibody-Western-Blot-NB100-142-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Mre11-Antibody-Western-Blot-NB100-142-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Mre11-Antibody-Immunocytochemistry-Immunofluorescence-NB100-142-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Mre11-Antibody-Immunocytochemistry-Immunofluorescence-NB100-142-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Mre11 Antibody-Chromatin Immunoprecipitation-NB100-142-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Mre11 Antibody-Chromatin Immunoprecipitation-NB100-142-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Mre11-Antibody-Knockdown-Validated-NB100-142-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/Mre11-Antibody-Knockdown-Validated-NB100-142-img0008.jpg
accessionNumbers :
P49959
应用 :
Western Blot, Simple Western, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Proximity Ligation Assay, Chromatin Immunoprecipitation (ChIP), Knockout Validated, Knockdown Validated
美元 :
399美元
别名 :
ATLDmeiotic recombination (S. cerevisiae) 11 homolog A, AT-like disease, DNA recombination and repair protein, double-strand break repair protein MRE11A, endo/exonuclease Mre11, HNGS1, Meiotic recombination 11 homolog 1, Meiotic recombination 11 homolog A, MRE11 homolog 1, MRE11 homolog A, MRE11 meiotic recombination 11 homolog A (S. cerevisiae), MRE11B
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。