产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
DEC1 Antibody - BSA Free
目录 :
NB100-1800
规格 :
0.1 ml (also 0.025 ml)
价格 :
459美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片
更多信息或购买 :
Novus Biologicals 产品网页
文章摘录数: 23
参考文献
Chen Z, Javed N, Moore M, Wu J, Sun G, Vinyard M, et al. Integrative dissection of gene regulatory elements at base resolution. Cell Genom. 2023;3:100318 pubmed 出版商
Pathmanapan S, Poon R, de Renshaw T, Nadesan P, Nakagawa M, Seesankar G, et al. Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation. Cell Rep. 2023;42:112578 pubmed 出版商
Nechanitzky R, Nechanitzky D, Ramachandran P, Duncan G, Zheng C, G xf6 bl C, et al. Cholinergic control of Th17 cell pathogenicity in experimental autoimmune encephalomyelitis. Cell Death Differ. 2023;30:407-416 pubmed 出版商
Hu X, Zou M, Ni L, Zhang M, Zheng W, Liu B, et al. Dec1 Deficiency Ameliorates Pulmonary Fibrosis Through the PI3K/AKT/GSK-3β/β-Catenin Integrated Signaling Pathway. Front Pharmacol. 2022;13:829673 pubmed 出版商
Sato F, Bhawal U, Osaki S, Sugiyama N, Oikawa K, Muragaki Y. Differential immunohistochemical expression of DEC1, CK‑1ε, and CD44 in oral atypical squamous epithelium and carcinoma in situ. Mol Med Rep. 2022;25: pubmed 出版商
Zhong Y, Walker S, Pritykin Y, Leslie C, Rudensky A, van der Veeken J. Hierarchical regulation of the resting and activated T cell epigenome by major transcription factor families. Nat Immunol. 2022;23:122-134 pubmed 出版商
Rauschmeier R, Reinhardt A, Gustafsson C, Glaros V, Artemov A, Dunst J, et al. Bhlhe40 function in activated B and TFH cells restrains the GC reaction and prevents lymphomagenesis. J Exp Med. 2022;219: pubmed 出版商
Uyeda M, Freeborn R, Cieniewicz B, Romano R, Chen P, Liu J, et al. BHLHE40 Regulates IL-10 and IFN-γ Production in T Cells but Does Not Interfere With Human Type 1 Regulatory T Cell Differentiation. Front Immunol. 2021;12:683680 pubmed 出版商
Sato F, Bhawal U, Sugiyama N, Osaki S, Oikawa K, Muragaki Y. Potential Role of DEC1 in Cervical Cancer Cells Involving Overexpression and Apoptosis. Clocks Sleep. 2020;2:26-38 pubmed 出版商
Hu G, Dong X, Gong S, Song Y, Hutchins A, Yao H. Systematic screening of CTCF binding partners identifies that BHLHE40 regulates CTCF genome-wide distribution and long-range chromatin interactions. Nucleic Acids Res. 2020;48:9606-9620 pubmed 出版商
Pasula S, Tessneer K, Fu Y, Gopalakrishnan J, Pelikan R, Kelly J, et al. Role of Systemic Lupus Erythematosus Risk Variants With Opposing Functional Effects as a Driver of Hypomorphic Expression of TNIP1 and Other Genes Within a Three-Dimensional Chromatin Network. Arthritis Rheumatol. 2020;72:780-790 pubmed 出版商
Le H, Sato F, Kohsaka A, Bhawal U, Nakao T, Muragaki Y, et al. Dec1 Deficiency Suppresses Cardiac Perivascular Fibrosis Induced by Transverse Aortic Constriction. Int J Mol Sci. 2019;20: pubmed 出版商
Li C, Zhu B, Son Y, Wang Z, Jiang L, Xiang M, et al. The Transcription Factor Bhlhe40 Programs Mitochondrial Regulation of Resident CD8+ T Cell Fitness and Functionality. Immunity. 2019;51:491-507.e7 pubmed 出版商
Rauschmeier R, Gustafsson C, Reinhardt A, A Gonzalez N, Tortola L, Cansever D, et al. Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self-renewal and identity. EMBO J. 2019;38:e101233 pubmed 出版商
Jarjour N, Schwarzkopf E, Bradstreet T, Shchukina I, Lin C, Huang S, et al. Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity. Nat Immunol. 2019;20:687-700 pubmed 出版商
Sato F, Otsuka T, Kohsaka A, Le H, Bhawal U, Muragaki Y. Smad3 Suppresses Epithelial Cell Migration and Proliferation Via the Clock Gene Dec1, Which Negatively Regulates the Expression of Clock Genes Dec2 and Per1. Am J Pathol. 2019;: pubmed 出版商
Huynh J, Lin C, Kimmey J, Jarjour N, Schwarzkopf E, Bradstreet T, et al. Bhlhe40 is an essential repressor of IL-10 during Mycobacterium tuberculosis infection. J Exp Med. 2018;215:1823-1838 pubmed 出版商
Hamilton K, Wang Y, Raefsky S, Berkowitz S, Spangler R, Suire C, et al. Mice lacking the transcriptional regulator Bhlhe40 have enhanced neuronal excitability and impaired synaptic plasticity in the hippocampus. PLoS ONE. 2018;13:e0196223 pubmed 出版商
Nakamura H, Bono H, Hiyama K, Kawamoto T, Kato Y, Nakanishi T, et al. Differentiated embryo chondrocyte plays a crucial role in DNA damage response via transcriptional regulation under hypoxic conditions. PLoS ONE. 2018;13:e0192136 pubmed 出版商
Liu Q, Imaizumi T, Murakami K, Tanaka H, Wu Y, Yoshizawa T, et al. DEC1 negatively regulates the expression of CXCL10 and CCL5 induced by poly IC in normal human mesangial cells. Biomed Res. 2017;38:249-255 pubmed 出版商
Murakami K, Wu Y, Imaizumi T, Aoki Y, Liu Q, Yan X, et al. DEC1 promotes hypoxia-induced epithelial-mesenchymal transition (EMT) in human hepatocellular carcinoma cells. Biomed Res. 2017;38:221-227 pubmed 出版商
Sato F, Kohsaka A, Takahashi K, Otao S, Kitada Y, Iwasaki Y, et al. Smad3 and Bmal1 regulate p21 and S100A4 expression in myocardial stromal fibroblasts via TNF-?. Histochem Cell Biol. 2017;148:617-624 pubmed 出版商
Sato H, Wu Y, Kato Y, Liu Q, Hirai H, Yoshizawa T, et al. DEC2 expression antagonizes cisplatin‑induced apoptosis in human esophageal squamous cell carcinoma. Mol Med Rep. 2017;16:43-48 pubmed 出版商
图像
图像 1 :
Novus Biologicals NB100-1800 图像 1
Western Blot: DEC1 Antibody [NB100-1800] - Western Blot Image of anti-DEC1. Whole cell protein from A431 (lane 1) and PC3 (lane 2) was separated on a 12% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2 ug/ml anti-DEC1 in 1% milk, and detected with an anti-rabbit HRP secondary antibody using chemiluminescence.
产品信息
品牌 :
Novus
MasterCode :
NB100-1800
SKU号 :
NB100-1800
产品名称 :
DEC1 Antibody - BSA Free
描述 :
The DEC1 Antibody - BSA Free from NB100-1800 is a nb100-1800 antibody to . This antibody reacts with hif target genes, hypoxia. The DEC1 Antibody - BSA Free has been validated for the following applications: O14503.
靶标 :
1-Dec
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
兔
免疫原 :
Synthetic peptide made to a C-terminal region of human DEC1 (between amino acids 350-412) [UniProt O14503]
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类, 小鼠, 大鼠
理论上的分子量 :
46 kDa
基因符号 :
BHLHE40
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Western-Blot-NB100-1800-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Western-Blot-NB100-1800-img0011.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Immunocytochemistry-Immunofluorescence-NB100-1800-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Immunocytochemistry-Immunofluorescence-NB100-1800-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Immunohistochemistry-NB100-1800-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Immunohistochemistry-NB100-1800-img0017.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Flow-Cytometry-NB100-1800-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Flow-Cytometry-NB100-1800-img0016.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1 Antibody - BSA Free-Western Blot-NB100-1800-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1 Antibody - BSA Free-Western Blot-NB100-1800-img0018.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Western-Blot-NB100-1800-img0001.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Western-Blot-NB100-1800-img0001.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Immunohistochemistry-Paraffin-NB100-1800-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Immunohistochemistry-Paraffin-NB100-1800-img0012.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Immunoprecipitation-NB100-1800-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Immunoprecipitation-NB100-1800-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Simple-Western-NB100-1800-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Simple-Western-NB100-1800-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Immunoblotting-NB100-1800-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Immunoblotting-NB100-1800-img0013.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Immunoblotting-NB100-1800-img0014.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Immunoblotting-NB100-1800-img0014.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Immunoblotting-NB100-1800-img0015.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/DEC1-Antibody---BSA-Free-Immunoblotting-NB100-1800-img0015.jpg
accessionNumbers :
O14503
应用 :
Western Blot, Simple Western, Chromatin Immunoprecipitation, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunoblotting, Chromatin Immunoprecipitation (ChIP), Chromatin Immunoprecipitation Sequencing
美元 :
459美元
别名 :
basic helix-loop-helix domain containing, class B, 2, basic helix-loop-helix family, member e40, bHLHb2, bHLHe40, Class B basic helix-loop-helix protein 2, class E basic helix-loop-helix protein 40, DEC1HLHB2, differentially expressed in chondrocytes 1, Differentially expressed in chondrocytes protein 1, differentiated embryo chondrocyte expressed gene 1, Enhancer-of-split and hairy-related protein 2, SHARP2, SHARP-2, Stimulated by retinoic acid gene 13 protein, STRA13FLJ99214, Stra14
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
更多信息或购买 :
Novus Biologicals 产品网页
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工，Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外，Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂，Novus Biologicals扮演市场上重要的角色。