产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
LC3B抗体
目录 :
NB100-2220
规格 :
0.025毫升
价格 :
149美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
豚鼠, 人类, 小鼠, 大鼠, , , , 斑马鱼
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, proximity ligation assay
更多信息或购买 :
文章摘录数: 722
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 2a
Tang C, Han H, Liu Z, Liu Y, Yin L, Cai J, et al. Activation of BNIP3-mediated mitophagy protects against renal ischemia-reperfusion injury. Cell Death Dis. 2019;10:677 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s2a
  • 免疫印迹; 人类; 图 2a
Yang M, Chen P, Liu J, Zhu S, Kroemer G, Klionsky D, et al. Clockophagy is a novel selective autophagy process favoring ferroptosis. Sci Adv. 2019;5:eaaw2238 pubmed 出版商
  • 免疫印迹; 小鼠; 1:20,000; 图 6h
Jung S, Choe S, Woo H, Jeong H, An H, Moon H, et al. Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits. Autophagy. 2019;:1-19 pubmed 出版商
  • 免疫印迹; 人类; 图 3g
Park H, Chung K, An H, Gim J, Hong J, Woo H, et al. Parkin Promotes Mitophagic Cell Death in Adult Hippocampal Neural Stem Cells Following Insulin Withdrawal. Front Mol Neurosci. 2019;12:46 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Huang X, Gan G, Wang X, Xu T, Xie W. The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance. Autophagy. 2019;15:1258-1279 pubmed 出版商
  • 免疫印迹; 豚鼠; 图 7b
Zhang Y, Jiang Q, Xie S, Wu X, Zhou J, Sun H. Lead Induced Ototoxicity and Neurotoxicity in Adult Guinea Pig. Biomed Res Int. 2019;2019:3626032 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Wang W, Xia Z, Farre J, Subramani S. TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axis. Autophagy. 2018;14:1574-1585 pubmed 出版商
  • 免疫印迹; 人类; 图 3c
Marrone L, Bus C, Schöndorf D, Fitzgerald J, Kübler M, Schmid B, et al. Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease. PLoS ONE. 2018;13:e0192497 pubmed 出版商
  • 免疫印迹; 人类; 1:3000; 图 1b
Hsu C, Lee E, Gordon K, Paz E, Shen W, Ohnishi K, et al. MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB. Nat Commun. 2018;9:942 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Agod Z, Pazmandi K, Bencze D, Vereb G, Biro T, Szabo A, et al. Signaling Lymphocyte Activation Molecule Family 5 Enhances Autophagy and Fine-Tunes Cytokine Response in Monocyte-Derived Dendritic Cells via Stabilization of Interferon Regulatory Factor 8. Front Immunol. 2018;9:62 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Goiran T, Duplan E, Rouland L, El Manaa W, Lauritzen I, Dunys J, et al. Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation. Cell Death Differ. 2018;25:873-884 pubmed 出版商
  • 免疫印迹; 小鼠; 1:3000; 图 4b
Sun H, Krauss R, Chang J, Teng B. PCSK9 deficiency reduces atherosclerosis, apolipoprotein B secretion, and endothelial dysfunction. J Lipid Res. 2018;59:207-223 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 5g
Lüningschrör P, Binotti B, Dombert B, Heimann P, Pérez Lara A, Slotta C, et al. Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease. Nat Commun. 2017;8:678 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2f
Bartolomeo R, Cinque L, De Leonibus C, Forrester A, Salzano A, Monfregola J, et al. mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy. J Clin Invest. 2017;127:3717-3729 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2c
Rocchi A, Yamamoto S, Ting T, Fan Y, SADLEIR K, Wang Y, et al. A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease. PLoS Genet. 2017;13:e1006962 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1f
Button R, Roberts S, Willis T, Hanemann C, Luo S. Accumulation of autophagosomes confers cytotoxicity. J Biol Chem. 2017;292:13599-13614 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2c
Wu D, Adamopoulos I. Loss of WDFY3 ameliorates severity of serum transfer-induced arthritis independently of autophagy. Cell Immunol. 2017;316:61-69 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1a
  • 免疫印迹; 人类; 图 e4d
Ashkenazi A, Bento C, Ricketts T, Vicinanza M, Siddiqi F, Pavel M, et al. Polyglutamine tracts regulate beclin 1-dependent autophagy. Nature. 2017;545:108-111 pubmed 出版商
  • 免疫印迹; 斑马鱼; 图 3d
  • 免疫印迹; 人类; 图 5b
Zhang Y, Nguyen D, Olzomer E, Poon G, Cole N, Puvanendran A, et al. Rescue of Pink1 Deficiency by Stress-Dependent Activation of Autophagy. Cell Chem Biol. 2017;24:471-480.e4 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4d
Delaney J, Patel C, Willis K, Haghighiabyaneh M, Axelrod J, Tancioni I, et al. Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer. Nat Commun. 2017;8:14423 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 8c
Granato M, Rizzello C, Gilardini Montani M, Cuomo L, Vitillo M, Santarelli R, et al. Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways. J Nutr Biochem. 2017;41:124-136 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 5a
Hosoya M, Fujioka M, Sone T, Okamoto S, Akamatsu W, Ukai H, et al. Cochlear Cell Modeling Using Disease-Specific iPSCs Unveils a Degenerative Phenotype and Suggests Treatments for Congenital Progressive Hearing Loss. Cell Rep. 2017;18:68-81 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 1b
Wei Y, Chiang W, Sumpter R, Mishra P, Levine B. Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor. Cell. 2017;168:224-238.e10 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1f
Lee M, Sumpter R, Zou Z, Sirasanagandla S, Wei Y, Mishra P, et al. Peroxisomal protein PEX13 functions in selective autophagy. EMBO Rep. 2017;18:48-60 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3f
Fan Y, Wang N, Rocchi A, Zhang W, Vassar R, Zhou Y, et al. Identification of natural products with neuronal and metabolic benefits through autophagy induction. Autophagy. 2017;13:41-56 pubmed 出版商
  • 免疫印迹; 人类; 1:3000; 图 3a
Pavel M, Imarisio S, Menzies F, Jimenez Sanchez M, Siddiqi F, Wu X, et al. CCT complex restricts neuropathogenic protein aggregation via autophagy. Nat Commun. 2016;7:13821 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3d
Su F, Myers V, Knezevic T, Wang J, Gao E, Madesh M, et al. Bcl-2-associated athanogene 3 protects the heart from ischemia/reperfusion injury. JCI Insight. 2016;1:e90931 pubmed 出版商
  • 免疫印迹; 人类; 图 1h
Li D, Xie B, Wu X, Li J, Ding Y, Wen X, et al. Late-stage inhibition of autophagy enhances calreticulin surface exposure. Oncotarget. 2016;7:80842-80854 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 5a
Cai Y, Yang L, Hu G, Chen X, Niu F, Yuan L, et al. Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy. J Cell Biol. 2016;215:245-258 pubmed
  • 免疫组化; 人类; 图 5a
White S, McDermott M, Sufit R, Kosmac K, Bugg A, Gonzalez Freire M, et al. Walking performance is positively correlated to calf muscle fiber size in peripheral artery disease subjects, but fibers show aberrant mitophagy: an observational study. J Transl Med. 2016;14:284 pubmed 出版商
  • 免疫印迹; 人类; 图 5b
Teo W, Kerr M, Teasdale R. MTMR4 Is Required for the Stability of the Salmonella-Containing Vacuole. Front Cell Infect Microbiol. 2016;6:91 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Cudré Cung H, Zavadakova P, Do Vale Pereira S, Remacle N, Henry H, Ivanisevic J, et al. Ammonium accumulation is a primary effect of 2-methylcitrate exposure in an in vitro model for brain damage in methylmalonic aciduria. Mol Genet Metab. 2016;119:57-67 pubmed 出版商
  • 免疫印迹; 人类; 图 4e
Lin M, Liu H, Xiong Q, Niu H, Cheng Z, Yamamoto A, et al. Ehrlichia secretes Etf-1 to induce autophagy and capture nutrients for its growth through RAB5 and class III phosphatidylinositol 3-kinase. Autophagy. 2016;12:2145-2166 pubmed
  • 免疫印迹; 人类; 图 1e
Jo Y, Park N, Park S, Kim B, Shin J, Jo D, et al. O-GlcNAcylation of ATG4B positively regulates autophagy by increasing its hydroxylase activity. Oncotarget. 2016;7:57186-57196 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 6
Zea A, Stewart T, Ascani J, Tate D, Finkel Jimenez B, Wilk A, et al. Activation of the IL-2 Receptor in Podocytes: A Potential Mechanism for Podocyte Injury in Idiopathic Nephrotic Syndrome?. PLoS ONE. 2016;11:e0157907 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Dejesus R, Moretti F, McAllister G, Wang Z, Bergman P, Liu S, et al. Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62. elife. 2016;5: pubmed 出版商
  • 免疫细胞化学; 人类; 图 3
  • 免疫印迹; 人类; 1:1000; 图 3
Davis M, Delaney J, Patel C, Storgard R, Stupack D. Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings. Drug Des Devel Ther. 2016;10:1837-46 pubmed 出版商
  • 免疫印迹; 人类
Kuramoto K, Wang N, Fan Y, Zhang W, Schoenen F, Frankowski K, et al. Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids. Autophagy. 2016;12:1460-71 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 2d
  • 免疫印迹; 人类; 1:1000; 图 5b
Wijdeven R, Janssen H, Nahidiazar L, Janssen L, Jalink K, Berlin I, et al. Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway. Nat Commun. 2016;7:11808 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1a
Barnard R, Regan D, Hansen R, Maycotte P, Thorburn A, Gustafson D. Autophagy Inhibition Delays Early but Not Late-Stage Metastatic Disease. J Pharmacol Exp Ther. 2016;358:282-93 pubmed 出版商
  • 免疫印迹; 人类; 图 4b
Park S, Yi H, Suh N, Park Y, Koh J, Jeong S, et al. Inhibition of EHMT2/G9a epigenetically increases the transcription of Beclin-1 via an increase in ROS and activation of NF-?B. Oncotarget. 2016;7:39796-39808 pubmed 出版商
  • 免疫印迹; 大鼠; 图 10
  • 免疫细胞化学; 小鼠; 图 7
  • 免疫印迹; 小鼠; 图 1
Song J, Sun Y, Peluso I, Zeng Y, Yu X, Lu J, et al. A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition. Autophagy. 2016;12:1372-89 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
Pastore N, Brady O, Diab H, Martina J, Sun L, Huynh T, et al. TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages. Autophagy. 2016;12:1240-58 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Lopes V, Loitto V, Audinot J, Bayat N, Gutleb A, Cristobal S. Dose-dependent autophagic effect of titanium dioxide nanoparticles in human HaCaT cells at non-cytotoxic levels. J Nanobiotechnology. 2016;14:22 pubmed 出版商
  • 免疫印迹; 斑马鱼; 1:2000; 图 s2
Ruparelia A, Oorschot V, Ramm G, Bryson Richardson R. FLNC myofibrillar myopathy results from impaired autophagy and protein insufficiency. Hum Mol Genet. 2016;25:2131-2142 pubmed
  • 免疫印迹; 小鼠
Liu Y, Takahashi Y, Desai N, Zhang J, Serfass J, Shi Y, et al. Bif-1 deficiency impairs lipid homeostasis and causes obesity accompanied by insulin resistance. Sci Rep. 2016;6:20453 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s1
  • 免疫印迹; 小鼠; 1:1000; 图 6
Wu X, Fleming A, Ricketts T, Pavel M, Virgin H, Menzies F, et al. Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis. Nat Commun. 2016;7:10533 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Gentry E, Henderson B, Arrant A, Gearing M, Feng Y, Riddle N, et al. Rho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal Degeneration. J Neurosci. 2016;36:1316-23 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 1
Button R, Vincent J, Strang C, Luo S. Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis. Oncotarget. 2016;7:5157-75 pubmed 出版商
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Mukherjee R, Chakrabarti O. Ubiquitin-mediated regulation of the E3 ligase GP78 by MGRN1 in trans affects mitochondrial homeostasis. J Cell Sci. 2016;129:757-73 pubmed 出版商
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Kraft L, Manral P, Dowler J, Kenworthy A. Nuclear LC3 Associates with Slowly Diffusing Complexes that Survey the Nucleolus. Traffic. 2016;17:369-99 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 2e
Stotland A, Gottlieb R. α-MHC MitoTimer mouse: In vivo mitochondrial turnover model reveals remarkable mitochondrial heterogeneity in the heart. J Mol Cell Cardiol. 2016;90:53-8 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 s4b
Sorrell S, Golder Z, Johnstone D, Frankl F. Renal peroxiredoxin 6 interacts with anion exchanger 1 and plays a novel role in pH homeostasis. Kidney Int. 2016;89:105-112 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Hermanova I, Arruabarrena Aristorena A, Valis K, Nůsková H, Alberich Jorda M, Fiser K, et al. Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of l-asparaginase in childhood ALL cells. Leukemia. 2016;30:209-18 pubmed 出版商
  • 免疫印迹; 大鼠; 图 5
Chesser A, Ganeshan V, Yang J, Johnson G. Epigallocatechin-3-gallate enhances clearance of phosphorylated tau in primary neurons. Nutr Neurosci. 2016;19:21-31 pubmed 出版商
  • 免疫印迹; 人类
Hsuan S, Chyau C, Hung H, Chen J, Chou F. The induction of apoptosis and autophagy by Wasabia japonica extract in colon cancer. Eur J Nutr. 2016;55:491-503 pubmed 出版商
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Xu Y, Tian C, Sun J, Zhang J, Ren K, Fan X, et al. FBXW7-Induced MTOR Degradation Forces Autophagy to Counteract Persistent Prion Infection. Mol Neurobiol. 2016;53:706-719 pubmed 出版商
Besemer A, Maus J, Ax M, Stein A, Vo S, Freese C, et al. Receptor-mediated endocytosis 8 (RME-8)/DNAJC13 is a novel positive modulator of autophagy and stabilizes cellular protein homeostasis. Cell Mol Life Sci. 2020;: pubmed 出版商
Scoles D, Dansithong W, Pflieger L, Paul S, Gandelman M, Figueroa K, et al. ALS-associated genes in SCA2 mouse spinal cord transcriptomes. Hum Mol Genet. 2020;29:1658-1672 pubmed 出版商
D Adamo S, Cetrullo S, Guidotti S, Silvestri Y, Minguzzi M, Santi S, et al. Spermidine rescues the deregulated autophagic response to oxidative stress of osteoarthritic chondrocytes. Free Radic Biol Med. 2020;153:159-172 pubmed 出版商
Nóbrega C, Conceição A, Costa R, Koppenol R, Sequeira R, Nunes R, et al. The cholesterol 24-hydroxylase activates autophagy and decreases mutant huntingtin build-up in a neuroblastoma culture model of Huntington's disease. BMC Res Notes. 2020;13:210 pubmed 出版商
Khobrekar N, Quintremil S, Dantas T, Vallee R. The Dynein Adaptor RILP Controls Neuronal Autophagosome Biogenesis, Transport, and Clearance. Dev Cell. 2020;53:141-153.e4 pubmed 出版商
Tsang Y, Wang Y, Kong K, Grzeskowiak C, Zagorodna O, Dogruluk T, et al. Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression. elife. 2020;9: pubmed 出版商
Du Y, Qian Y, Tang X, Guo Y, Chen S, Jiang M, et al. Chloroquine attenuates lithium-induced NDI and proliferation of renal collecting duct cells. Am J Physiol Renal Physiol. 2020;318:F1199-F1209 pubmed 出版商
Lv X, Zhang Y, Liu X, Zheng H, Liu C, Zeng X, et al. TMEM16A ameliorates vascular remodeling by suppressing autophagy via inhibiting Bcl-2-p62 complex formation. Theranostics. 2020;10:3980-3993 pubmed 出版商
Intartaglia D, Giamundo G, Marrocco E, Maffia V, Salierno F, Nusco E, et al. Retinal Degeneration in MPS-IIIA Mouse Model. Front Cell Dev Biol. 2020;8:132 pubmed 出版商
Mutvei A, Nagiec M, Hamann J, Kim S, Vincent C, Blenis J. Rap1-GTPases control mTORC1 activity by coordinating lysosome organization with amino acid availability. Nat Commun. 2020;11:1416 pubmed 出版商
Jin L, Yuan F, Dai G, Yao Q, Xiang H, Wang L, et al. Blockage of O-linked GlcNAcylation induces AMPK-dependent autophagy in bladder cancer cells. Cell Mol Biol Lett. 2020;25:17 pubmed 出版商
Lüningschrör P, Werner G, Stroobants S, Kakuta S, Dombert B, Sinske D, et al. The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons. Cell Rep. 2020;30:3506-3519.e6 pubmed 出版商
Liang J, Lingeman E, Luong T, Ahmed S, Muhar M, Nguyen T, et al. A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation. Cell. 2020;180:1160-1177.e20 pubmed 出版商
Towers C, Wodetzki D, Thorburn A. Autophagy-dependent cancer cells circumvent loss of the upstream regulator RB1CC1/FIP200 and loss of LC3 conjugation by similar mechanisms. Autophagy. 2020;16:1332-1340 pubmed 出版商
Xie B, Zhao M, Song D, Wu K, Yi L, Li W, et al. Induction of autophagy and suppression of type I IFN secretion by CSFV. Autophagy. 2020;:1-23 pubmed 出版商
Naso F, Intartaglia D, Falanga D, Soldati C, Polishchuk E, Giamundo G, et al. Light-responsive microRNA miR-211 targets Ezrin to modulate lysosomal biogenesis and retinal cell clearance. EMBO J. 2020;39:e102468 pubmed 出版商
Pla Martín D, Schatton D, Wiederstein J, Marx M, Khiati S, Kruger M, et al. CLUH granules coordinate translation of mitochondrial proteins with mTORC1 signaling and mitophagy. EMBO J. 2020;39:e102731 pubmed 出版商
Montilla A, Zabala A, Matute C, Domercq M. Functional and Metabolic Characterization of Microglia Culture in a Defined Medium. Front Cell Neurosci. 2020;14:22 pubmed 出版商
Lee J, Wolfe D, Darji S, McBrayer M, Colacurcio D, Kumar A, et al. β2-adrenergic Agonists Rescue Lysosome Acidification and Function in PSEN1 Deficiency by Reversing Defective ER-to-lysosome Delivery of ClC-7. J Mol Biol. 2020;432:2633-2650 pubmed 出版商
Wang Z, Yang C, Liu J, Chun Kit Tong B, Zhu Z, Malampati S, et al. A Curcumin Derivative Activates TFEB and Protects Against Parkinsonian Neurotoxicity inVitro. Int J Mol Sci. 2020;21: pubmed 出版商
Franco Iborra S, Plaza Zabala A, Montpeyo M, Sebastian D, Vila M, Martinez Vicente M. Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease. Autophagy. 2020;:1-18 pubmed 出版商
Wu W, Wu Y, Mayer K, von Rosenstiel C, Schecker J, Baur S, et al. Lipid Peroxidation Plays an Important Role in Chemotherapeutic Effects of Temozolomide and the Development of Therapy Resistance in Human Glioblastoma. Transl Oncol. 2020;13:100748 pubmed 出版商
Georgila K, Gounis M, Havaki S, Gorgoulis V, Eliopoulos A. mTORC1-dependent protein synthesis and autophagy uncouple in the regulation of Apolipoprotein A-I expression. Metabolism. 2020;105:154186 pubmed 出版商
Iaconis D, Crina C, Brillante S, Indrieri A, Morleo M, Franco B. The HOPS complex subunit VPS39 controls ciliogenesis through autophagy. Hum Mol Genet. 2020;29:1018-1029 pubmed 出版商
Zhuang X, Wang S, Tan Y, Song J, Zhu Z, Wang Z, et al. Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson's disease models. Cell Death Dis. 2020;11:128 pubmed 出版商
Ishikawa M, Takaseki S, Yoshitomi T, Covey D, Zorumski C, Izumi Y. The neurosteroid allopregnanolone protects retinal neurons by effects on autophagy and GABRs/GABAA receptors in rat glaucoma models. Autophagy. 2020;:1-18 pubmed 出版商
Pötsch M, Ishida J, Palus S, Tschirner A, von Haehling S, Doehner W, et al. MT-102 prevents tissue wasting and improves survival in a rat model of severe cancer cachexia. J Cachexia Sarcopenia Muscle. 2020;11:594-605 pubmed 出版商
Hale A, Merchant M, White M. Detection and analysis of autophagy in the American alligator (Alligator mississippiensis). J Exp Zool B Mol Dev Evol. 2020;334:192-207 pubmed 出版商
Liu Z, Liu N, Huang S, Lin M, Qin S, Wu J, et al. NADPH protects against kainic acid-induced excitotoxicity via autophagy-lysosome pathway in rat striatum and primary cortical neurons. Toxicology. 2020;435:152408 pubmed 出版商
Dumas K, Ayachi C, Gilleron J, Lacas Gervais S, Pastor F, Favier F, et al. REDD1 deficiency protects against nonalcoholic hepatic steatosis induced by high-fat diet. FASEB J. 2020;34:5046-5060 pubmed 出版商
Yang C, Zhu Z, Tong B, Iyaswamy A, Xie W, Zhu Y, et al. A stress response p38 MAP kinase inhibitor SB202190 promoted TFEB/TFE3-dependent autophagy and lysosomal biogenesis independent of p38. Redox Biol. 2020;32:101445 pubmed 出版商
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产品信息
品牌 :
Novus
SKU号 :
NB100-2220
产品名称 :
LC3B抗体
单位尺寸 :
0.025毫升
描述 :
The LC3B Antibody from Novus is a rabbit polyclonal antibody to LC3B. This antibody reacts with human, mouse, rat, porcine, avian, bacteria, bovine, canine, chicken, guinea pig, hamster, invertebrate, monkey, primate, rabbit, golden syrian hamster, zebrafish. The LC3B Antibody has been validated for the following applications: Western Blot, Simple Western, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Proximity Ligation Assay, Chromatin Immunoprecipitation (ChIP), Knockout Validated, Knockdown Validated.
靶标 :
LC3B
类别 :
一抗
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
Polyclonal LC3B Antibody was made to a synthetic peptide made to an N-terminal portion of the human LC3B protein sequence (between residues 1-100). [UniProt# Q9GZQ8]
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
Human, Mouse, Rat, Porcine, Avian, Bacteria, Bovine, Canine, Chicken, Guinea Pig, Hamster, Invertebrate, Monkey, Primate, Rabbit, Golden Syrian Hamster, Zebrafish
理论上的分子量 :
14.688 kDa
基因符号 :
MAP1LC3B
catalog number base :
NB100-2220
应用 :
Western Blot, Simple Western, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Proximity Ligation Assay, Chromatin Immunoprecipitation (ChIP), Knockout Validated, Knockdown Validated
美元 :
149美元
applications abr :
WB, Simple Western, Flow, ELISA, IHC, ICC/IF, IP, IHC-P, IHC-Fr, IB, PLA, ChIP, KO, KD
别名 :
anti-LC3B, atg8f , Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, LC3B, lc3b autophagy marker, LC3B ihc, LC3B immunohistochemistry, LC3B immunoprecipitation, LC3B western blot, lc3-i, ii, MAP1 light chain 3-like protein 2, MAP1A/1BLC3, MAP1A/MAP1B LC3 B, map1lc3b, MAP1LC3B-a, microtubule associated protein 1 light chain 3 beta, microtubule associated protein 3 b, microtubule associated protein 3 beta, microtubule-associated proteins 1A/1B light chain 3, microtubule-associated proteins 1A/1B light chain 3B
储存 :
存放在-20C
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。