| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
| Cha S, Lee S, Wang J, Zhao Q, Bai D. Enhanced Circadian Clock in MSCs-Based Cytotherapy Ameliorates Age-Related Temporomandibular Joint Condyle Degeneration. Int J Mol Sci. 2021;22: pubmed 出版商 |
- 染色质免疫沉淀
; 人类; ; 图 3f
- 免疫组化; 人类; 10 ug/ml; 图 s5a
| Xu L, Liu Y, Cheng Q, Shen Y, Yuan Y, Jiang X, et al. Bmal1 Downregulation Worsens Critical Limb Ischemia by Promoting Inflammation and Impairing Angiogenesis. Front Cardiovasc Med. 2021;8:712903 pubmed 出版商 |
- 免疫组化基因敲除验证; 小鼠; 1:1000; 图 4e
- 免疫印迹基因敲除验证; 小鼠; 图 2b
| Kim B, Kim J, Chun M, Park I, Kwak D, Choi M, et al. Multiplexed CRISPR-Cas9 system in a single adeno-associated virus to simultaneously knock out redundant clock genes. Sci Rep. 2021;11:2575 pubmed 出版商 |
| Burgermeister E, Battaglin F, Eladly F, Wu W, Herweck F, Schulte N, et al. Aryl hydrocarbon receptor nuclear translocator-like (ARNTL/BMAL1) is associated with bevacizumab resistance in colorectal cancer via regulation of vascular endothelial growth factor A. EBioMedicine. 2019;45:139-154 pubmed 出版商 |
| González J, Lee H, Vincent A, Hill A, Goode L, King G, et al. Circadian regulation of dentate gyrus excitability mediated by G-protein signaling. Cell Rep. 2023;42:112039 pubmed 出版商 |
| Zhang C, Chen L, Sun L, Jin H, Ren K, Liu S, et al. BMAL1 collaborates with CLOCK to directly promote DNA double-strand break repair and tumor chemoresistance. Oncogene. 2023;42:967-979 pubmed 出版商 |
| Jang D, Yang B, You M, Rim C, Kim H, Sung S, et al. Fluoxetine Decreases Phagocytic Function via REV-ERBα in Microglia. Neurochem Res. 2022;: pubmed 出版商 |
| Singla R, Mishra A, Lin H, Lorsung E, Le N, Tin S, et al. Haploinsufficiency of a Circadian Clock Gene Bmal1 (Arntl or Mop3) Causes Brain-Wide mTOR Hyperactivation and Autism-like Behavioral Phenotypes in Mice. Int J Mol Sci. 2022;23: pubmed 出版商 |
| Vanmunster M, Rojo Garcia A, Pacolet A, Dalle S, Koppo K, Jonkers I, et al. Mechanosensors control skeletal muscle mass, molecular clocks, and metabolism. Cell Mol Life Sci. 2022;79:321 pubmed 出版商 |
| Ye P, Li W, Huang X, Zhao S, Chen W, Xia Y, et al. BMAL1 regulates mitochondrial homeostasis in renal ischaemia-reperfusion injury by mediating the SIRT1/PGC-1α axis. J Cell Mol Med. 2022;26:1994-2009 pubmed 出版商 |
| McKee C, Lee J, Cai Y, Saito T, Saido T, Musiek E. Astrocytes deficient in circadian clock gene Bmal1 show enhanced activation responses to amyloid-beta pathology without changing plaque burden. Sci Rep. 2022;12:1796 pubmed 出版商 |
| de Zavalía N, Schoettner K, Goldsmith J, Solis P, Ferraro S, Parent G, et al. Bmal1 in the striatum influences alcohol intake in a sexually dimorphic manner. Commun Biol. 2021;4:1227 pubmed 出版商 |
| Gegnaw S, Sandu C, Mendoza J, Bergen A, Felder Schmittbuhl M. Dark-adapted light response in mice is regulated by a circadian clock located in rod photoreceptors. Exp Eye Res. 2021;213:108807 pubmed 出版商 |
| Trebucq L, Cardama G, Lorenzano Menna P, Golombek D, Chiesa J, Marpegan L. Timing of Novel Drug 1A-116 to Circadian Rhythms Improves Therapeutic Effects against Glioblastoma. Pharmaceutics. 2021;13: pubmed 出版商 |
| Huang W, Zheng X, Yang M, Li R, Song Y. PER2-mediated ameloblast differentiation via PPARγ/AKT1/β-catenin axis. Int J Oral Sci. 2021;13:16 pubmed 出版商 |
| Kim H, Wei J, Song Z, Mottillo E, Samavati L, Zhang R, et al. Regulation of hepatic circadian metabolism by the E3 ubiquitin ligase HRD1-controlled CREBH/PPARα transcriptional program. Mol Metab. 2021;49:101192 pubmed 出版商 |
| Sominsky L, Dangel T, Malik S, De Luca S, Singewald N, Spencer S. Microglial ablation in rats disrupts the circadian system. FASEB J. 2021;35:e21195 pubmed 出版商 |
| Wang X, Wolff S, Korpel N, Milanova I, Sandu C, Rensen P, et al. Deficiency of the Circadian Clock Gene Bmal1 Reduces Microglial Immunometabolism. Front Immunol. 2020;11:586399 pubmed 出版商 |
| Greco C, Cervantes M, Fustin J, Ito K, Ceglia N, Samad M, et al. S-adenosyl-l-homocysteine hydrolase links methionine metabolism to the circadian clock and chromatin remodeling. Sci Adv. 2020;6: pubmed 出版商 |
| Kim E, Xu Y, Cassidy R, Lu Y, Yang Y, Tian J, et al. Paraventricular hypothalamus mediates diurnal rhythm of metabolism. Nat Commun. 2020;11:3794 pubmed 出版商 |
| La Fuente J, Sevilleja Ortiz A, García Rojo E, El Assar M, Fernández A, Pepe Cardoso A, et al. Erectile dysfunction is associated with defective L-cysteine/hydrogen sulfide pathway in human corpus cavernosum and penile arteries. Eur J Pharmacol. 2020;884:173370 pubmed 出版商 |
| Chi T, Hsieh B, Liang P, Han T, Hsieh M. Expression and Functional Study of Single Mutations of Carbonic Anhydrase 8 in Neuronal Cells. Cell Mol Neurobiol. 2020;: pubmed 出版商 |
| Beauvarlet J, Nath Das R, Alvarez Valadez K, Martins I, Muller A, Darbo E, et al. Triarylpyridine Compounds and Chloroquine Act in Concert to Trigger Lysosomal Membrane Permeabilization and Cell Death in Cancer Cells. Cancers (Basel). 2020;12: pubmed 出版商 |
| Khodja Y, Samuels M. Ethanol-mediated upregulation of APOA1 gene expression in HepG2 cells is independent of de novo lipid biosynthesis. Lipids Health Dis. 2020;19:144 pubmed 出版商 |
| Wu C, Chang C, Yang T, Tsai A, Wang J, Chang C, et al. Tubular transcriptional co-activator with PDZ-binding motif protects against ischemic acute kidney injury. Clin Sci (Lond). 2020;134:1593-1612 pubmed 出版商 |
| Hsieh M, Hsieh M, Lo Y, Lin C, Chuang Y, Chen M, et al. Modulating effect of Coronarin D in 5-fluorouracil resistance human oral cancer cell lines induced apoptosis and cell cycle arrest through JNK1/2 signaling pathway. Biomed Pharmacother. 2020;128:110318 pubmed 出版商 |
| Alicea G, Rebecca V, Goldman A, Fane M, Douglass S, Behera R, et al. Changes in Aged Fibroblast Lipid Metabolism Induce Age-Dependent Melanoma Cell Resistance to Targeted Therapy via the Fatty Acid Transporter FATP2. Cancer Discov. 2020;10:1282-1295 pubmed 出版商 |
| Marshall J, Courage E, Elliott R, Fitzpatrick M, Kim A, Lopez Clavijo A, et al. THP-1 macrophage cholesterol efflux is impaired by palmitoleate through Akt activation. PLoS ONE. 2020;15:e0233180 pubmed 出版商 |
| Dan H, Ruan T, Sampogna R. Circadian Clock Regulation of Developmental Time in the Kidney. Cell Rep. 2020;31:107661 pubmed 出版商 |
| Oishi N, Hundal T, Phillips J, Dasari S, Hu G, Viswanatha D, et al. Molecular profiling reveals a hypoxia signature in breast implant-associated anaplastic large cell lymphoma. Haematologica. 2020;: pubmed 出版商 |
| Bartl S, Oueslati A, Southwell A, Siddu A, Parth M, David L, et al. Inhibiting cellular uptake of mutant huntingtin using a monoclonal antibody: Implications for the treatment of Huntington's disease. Neurobiol Dis. 2020;141:104943 pubmed 出版商 |
| Chang Y, Ko B, Ju J, Chang H, Huang S, Lin C. SARS Unique Domain (SUD) of Severe Acute Respiratory Syndrome Coronavirus Induces NLRP3 Inflammasome-Dependent CXCL10-Mediated Pulmonary Inflammation. Int J Mol Sci. 2020;21: pubmed 出版商 |
| Jin Y, Shen Y, Su X, Cai J, Liu Y, Weintraub N, et al. The Small GTPases Rab27b Regulates Mitochondrial Fatty Acid Oxidative Metabolism of Cardiac Mesenchymal Stem Cells. Front Cell Dev Biol. 2020;8:209 pubmed 出版商 |
| Barbier V, Erbani J, Fiveash C, Davies J, Tay J, Tallack M, et al. Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance. Nat Commun. 2020;11:2042 pubmed 出版商 |
| Li R, Li X, Hagood J, Zhu M, Sun X. Myofibroblast contraction is essential for generating and regenerating the gas-exchange surface. J Clin Invest. 2020;130:2859-2871 pubmed 出版商 |
| Romeo M, Gilardini Montani M, Benedetti R, Garufi A, D Orazi G, Cirone M. PBA Preferentially Impairs Cell Survival of Glioblastomas Carrying mutp53 by Reducing Its Expression Level, Stabilizing wtp53, Downregulating the Mevalonate Kinase and Dysregulating UPR. Biomolecules. 2020;10: pubmed 出版商 |
| Pei X, Kim H, Lee M, Wang N, Shin J, Lee S, et al. Local delivery of cardiac stem cells overexpressing HIF-1α promotes angiogenesis and muscular tissue repair in a hind limb ischemia model. J Control Release. 2020;322:610-621 pubmed 出版商 |
| Lin J, Chen S, Lu C, Lin J, Yen G. Ursolic acid promotes apoptosis, autophagy, and chemosensitivity in gemcitabine-resistant human pancreatic cancer cells. Phytother Res. 2020;: pubmed 出版商 |
| Laitakari A, Huttunen R, Kuvaja P, Hannuksela P, Szabo Z, Heikkilä M, et al. Systemic long-term inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 ameliorates aging-induced changes in mice without affecting their life span. FASEB J. 2020;34:5590-5609 pubmed 出版商 |
| Chen Y, Tsai C, Cheng Y, Nieh S, Yeh T, Chen C, et al. Impacts of Intralipid on Nanodrug Abraxane Therapy and on the Innate Immune System. Sci Rep. 2020;10:2838 pubmed 出版商 |
| Cheng C, Kao S, Lee Y. Angelica sinensis extract protects against ischemia-reperfusion injury in the hippocampus by activating p38 MAPK-mediated p90RSK/p-Bad and p90RSK/CREB/BDNF signaling after transient global cerebral ischemia in rats. J Ethnopharmacol. 2020;252:112612 pubmed 出版商 |
| Biswas L, Zeng Z, Graham A, Shu X. Gypenosides mediate cholesterol efflux and suppress oxidized LDL induced inflammation in retinal pigment epithelium cells. Exp Eye Res. 2020;191:107931 pubmed 出版商 |
| Lieberman O, Frier M, McGuirt A, Griffey C, Rafikian E, Yang M, et al. Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy. elife. 2020;9: pubmed 出版商 |
| Cho S, Chae J, Shin H, Shin Y, Kim Y, Kil E, et al. Enhanced Anticancer Effect of Adding Magnesium to Vitamin C Therapy: Inhibition of Hormetic Response by SVCT-2 Activation. Transl Oncol. 2020;13:401-409 pubmed 出版商 |
| Rogers M, Chen J, Nallamshetty S, Pham T, Goto S, Muehlschlegel J, et al. Retinoids Repress Human Cardiovascular Cell Calcification With Evidence for Distinct Selective Retinoid Modulator Effects. Arterioscler Thromb Vasc Biol. 2020;40:656-669 pubmed 出版商 |
| Langley M, Yoon H, Kim H, Choi C, Simon W, Kleppe L, et al. High fat diet consumption results in mitochondrial dysfunction, oxidative stress, and oligodendrocyte loss in the central nervous system. Biochim Biophys Acta Mol Basis Dis. 2020;1866:165630 pubmed 出版商 |
| Yuan P, Yang T, Mu J, Zhao J, Yang Y, Yan Z, et al. Circadian clock gene NPAS2 promotes reprogramming of glucose metabolism in hepatocellular carcinoma cells. Cancer Lett. 2020;469:498-509 pubmed 出版商 |
| Arima N, Sasaki Y, Lee L, Zhang H, Figueiredo J, Mlynarchik A, et al. Multiorgan Systems Study Reveals Igfbp7 as a Suppressor of Gluconeogenesis after Gastric Bypass Surgery. J Proteome Res. 2020;19:129-143 pubmed 出版商 |
| Xu Y, Xu Y, Zhu Y, Sun H, Juguilon C, Li F, et al. Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis. Mol Ther. 2020;28:202-216 pubmed 出版商 |
| Hughes B, Crofton E, O Buckley T, Herman M, Morrow A. Chronic ethanol exposure alters prelimbic prefrontal cortical Fast-Spiking and Martinotti interneuron function with differential sex specificity in rat brain. Neuropharmacology. 2020;162:107805 pubmed 出版商 |
| Wang C, Holtzman D. Bidirectional relationship between sleep and Alzheimer's disease: role of amyloid, tau, and other factors. Neuropsychopharmacology. 2020;45:104-120 pubmed 出版商 |
| Alhakamy N, Md S. Repurposing Itraconazole Loaded PLGA Nanoparticles for Improved Antitumor Efficacy in Non-Small Cell Lung Cancers. Pharmaceutics. 2019;11: pubmed 出版商 |
| Dos Santos Ortolan L, Sercundes M, Moura G, de Castro Quirino T, Debone D, de Sousa Costa D, et al. Endothelial Protein C Receptor Could Contribute to Experimental Malaria-Associated Acute Respiratory Distress Syndrome. J Immunol Res. 2019;2019:3105817 pubmed 出版商 |
| Hasegawa S, Fukushima H, Hosoda H, Serita T, Ishikawa R, Rokukawa T, et al. Hippocampal clock regulates memory retrieval via Dopamine and PKA-induced GluA1 phosphorylation. Nat Commun. 2019;10:5766 pubmed 出版商 |
| Lima F, Barateiro A, Dombrowski J, de Souza R, Costa D, Murillo O, et al. Plasmodium falciparum infection dysregulates placental autophagy. PLoS ONE. 2019;14:e0226117 pubmed 出版商 |
| Su X, Jin Y, Shen Y, Kim I, Weintraub N, Tang Y. RNAase III-Type Enzyme Dicer Regulates Mitochondrial Fatty Acid Oxidative Metabolism in Cardiac Mesenchymal Stem Cells. Int J Mol Sci. 2019;20: pubmed 出版商 |
| Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, et al. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing. Nature. 2019;574:553-558 pubmed 出版商 |
| Herroon M, Diedrich J, Rajagurubandara E, Martin C, Maddipati K, Kim S, et al. Prostate Tumor Cell-Derived IL1β Induces an Inflammatory Phenotype in Bone Marrow Adipocytes and Reduces Sensitivity to Docetaxel via Lipolysis-Dependent Mechanisms. Mol Cancer Res. 2019;17:2508-2521 pubmed 出版商 |
| Aladaileh S, Hussein O, Abukhalil M, Saghir S, Bin Jumah M, Alfwuaires M, et al. Formononetin Upregulates Nrf2/HO-1 Signaling and Prevents Oxidative Stress, Inflammation, and Kidney Injury in Methotrexate-Induced Rats. Antioxidants (Basel). 2019;8: pubmed 出版商 |
| Xing G, Jing H, Zhang L, Cao Y, Li L, Zhao K, et al. A mechanism in agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome. elife. 2019;8: pubmed 出版商 |
| Vande Walle L, Stowe I, Sácha P, Lee B, Demon D, Fossoul A, et al. MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition. PLoS Biol. 2019;17:e3000354 pubmed 出版商 |
| Holdgaard S, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen J, et al. Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites. Nat Commun. 2019;10:4176 pubmed 出版商 |
| Su S, Hung Y, Huang C, Shieh Y, Chien C, Chiang C, et al. Cilostazol inhibits hyperglucose-induced vascular smooth muscle cell dysfunction by modulating the RAGE/ERK/NF-κB signaling pathways. J Biomed Sci. 2019;26:68 pubmed 出版商 |
| Zhou T, Zhu T, Rivera J, Omri S, Tahiri H, Lahaie I, et al. The Inability of the Choroid to Revascularize in Oxygen-Induced Retinopathy Results from Increased p53/miR-Let-7b Activity. Am J Pathol. 2019;189:2340-2356 pubmed 出版商 |
| Li M, Peng W, Wu C, Chang Y, Lin Y, Chang G, et al. PTPN3 suppresses lung cancer cell invasiveness by counteracting Src-mediated DAAM1 activation and actin polymerization. Oncogene. 2019;38:7002-7016 pubmed 出版商 |
| Stroik S, Kurtz K, Hendrickson E. CtIP is essential for telomere replication. Nucleic Acids Res. 2019;47:8927-8940 pubmed 出版商 |
| Hao C, Liu G, Tian G. Autophagy inhibition of cancer stem cells promotes the efficacy of cisplatin against non-small cell lung carcinoma. Ther Adv Respir Dis. 2019;13:1753466619866097 pubmed 出版商 |
| Hayward D, Kouznetsova V, Pierson H, Hasan N, Guzman E, Tsigelny I, et al. ANKRD9 is a metabolically-controlled regulator of IMPDH2 abundance and macro-assembly. J Biol Chem. 2019;294:14454-14466 pubmed 出版商 |
| Hannibal J, Norn T, Georg B, Fahrenkrug J. Spatiotemporal expression pattern of PERIOD 1 and PERIOD 2 in the mouse SCN is dependent on VIP receptor 2 signaling. Eur J Neurosci. 2019;50:3115-3132 pubmed 出版商 |
| Tsolou A, Lamprou I, Fortosi A, Liousia M, Giatromanolaki A, Koukourakis M. 'Stemness' and 'senescence' related escape pathways are dose dependent in lung cancer cells surviving post irradiation. Life Sci. 2019;:116562 pubmed 出版商 |
| Wangsa D, Braun R, Stuelten C, Brown M, Bauer K, Emons G, et al. Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells. Neoplasia. 2019;21:721-729 pubmed 出版商 |
| Scheidecker S, Bär S, Stoetzel C, Geoffroy V, Lannes B, Rinaldi B, et al. Mutations in KARS cause a severe neurological and neurosensory disease with optic neuropathy. Hum Mutat. 2019;40:1826-1840 pubmed 出版商 |
| Li Z, Zhang S, Li J, Zeng H, Wang Y, Huang Y. Nerve regeneration in rat peripheral nerve allografts: Evaluation of cold-inducible RNA-binding protein in nerve storage and regeneration. J Comp Neurol. 2019;527:2885-2895 pubmed 出版商 |
| Saporiti F, Piacentini L, Alfieri V, Bono E, Ferrari F, Chiesa M, et al. Melanocortin-1 Receptor Positively Regulates Human Artery Endothelial Cell Migration. Cell Physiol Biochem. 2019;52:1339-1360 pubmed 出版商 |
| Luo Q, Xiao Y, Alex A, Cummins T, Bhatwadekar A. The Diurnal Rhythm of Insulin Receptor Substrate-1 (IRS-1) and Kir4.1 in Diabetes: Implications for a Clock Gene Bmal1. Invest Ophthalmol Vis Sci. 2019;60:1928-1936 pubmed 出版商 |
| Sakai S, Ohhata T, Kitagawa K, Uchida C, Aoshima T, Niida H, et al. Long Noncoding RNA ELIT-1 Acts as a Smad3 Cofactor to Facilitate TGFβ/Smad Signaling and Promote Epithelial-Mesenchymal Transition. Cancer Res. 2019;79:2821-2838 pubmed 出版商 |
| Chiba M, Ito Y, Nagasawa T. Phenethyl isothiocyanate stimulates glucose uptake through the Akt pathway in C2C12 myotubes. Biosci Biotechnol Biochem. 2019;83:1319-1328 pubmed 出版商 |
| Hughes B, Bohnsack J, O Buckley T, Herman M, Morrow A. Chronic Ethanol Exposure and Withdrawal Impair Synaptic GABAA Receptor-Mediated Neurotransmission in Deep-Layer Prefrontal Cortex. Alcohol Clin Exp Res. 2019;43:822-832 pubmed 出版商 |
| Wu H, Ploeger J, Kamarajugadda S, Mashek D, Mashek M, Manivel J, et al. Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in Hepatocytes. Hepatol Commun. 2019;3:406-422 pubmed 出版商 |
| Lee M, Miller Z, Park J, Bhattarai D, Lee W, Kim K. H727 cells are inherently resistant to the proteasome inhibitor carfilzomib, yet require proteasome activity for cell survival and growth. Sci Rep. 2019;9:4089 pubmed 出版商 |
| Cedernaes J, Huang W, Ramsey K, Waldeck N, Cheng L, Marcheva B, et al. Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron. Cell Metab. 2019;29:1078-1091.e5 pubmed 出版商 |
| Laitakari A, Ollonen T, Kietzmann T, Walkinshaw G, Mennerich D, Izzi V, et al. Systemic inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 in mice protects from alcohol-induced fatty liver disease. Redox Biol. 2019;22:101145 pubmed 出版商 |
| Ryzhikov M, Ehlers A, Steinberg D, Xie W, Oberlander E, Brown S, et al. Diurnal Rhythms Spatially and Temporally Organize Autophagy. Cell Rep. 2019;26:1880-1892.e6 pubmed 出版商 |
| Beauvarlet J, Bensadoun P, Darbo E, Labrunie G, Rousseau B, Richard E, et al. Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells. Nucleic Acids Res. 2019;47:2739-2756 pubmed 出版商 |
| van der Waals L, Laoukili J, Jongen J, Raats D, Borel Rinkes I, Kranenburg O. Differential anti-tumour effects of MTH1 inhibitors in patient-derived 3D colorectal cancer cultures. Sci Rep. 2019;9:819 pubmed 出版商 |
| Zhang H, Wei Q, Xiang X, Zhou B, Chen J, Li J, et al. Semaphorin 4A acts in a feed-forward loop with NF-κB pathway to exacerbate catabolic effect of IL-1β on chondrocytes. Int Immunopharmacol. 2019;69:88-94 pubmed 出版商 |
| Mega Tiber P, Kocyigit Sevinc S, Kilinc O, Orun O. Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562. Gene. 2019;692:217-222 pubmed 出版商 |
| Spence E, Dube S, Uezu A, Locke M, Soderblom E, Soderling S. In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation. Nat Commun. 2019;10:386 pubmed 出版商 |
| Even I, Reidenbach S, Schlechter T, Berns N, Herold R, Roth W, et al. DLIC1, but not DLIC2, is upregulated in colon cancer and this contributes to proliferative overgrowth and migratory characteristics of cancer cells. FEBS J. 2019;286:803-820 pubmed 出版商 |
| Ye R, Onodera T, Blanchard P, Kusminski C, Esser V, Brekken R, et al. β1 Syntrophin Supports Autophagy Initiation and Protects against Cerulein-Induced Acute Pancreatitis. Am J Pathol. 2019;189:813-825 pubmed 出版商 |
| Wang B, Pan J, Yu H, Xiong L, Zhao K, Xiong S, et al. Lack of Myosin X Enhances Osteoclastogenesis and Increases Cell Surface Unc5b in Osteoclast-Lineage Cells. J Bone Miner Res. 2019;34:939-954 pubmed 出版商 |
| Lee C, Yang J, Chen C, Tsai M, Hung P, Chen S, et al. Novel STAT3 Inhibitor LDOC1 Targets Phospho-JAK2 for Degradation by Interacting with LNX1 and Regulates the Aggressiveness of Lung Cancer. Cancers (Basel). 2019;11: pubmed 出版商 |
| Cheng C, Kao S, Lee Y. Ferulic Acid Exerts Anti-apoptotic Effects against Ischemic Injury by Activating HSP70/Bcl-2- and HSP70/Autophagy-Mediated Signaling after Permanent Focal Cerebral Ischemia in Rats. Am J Chin Med. 2019;47:39-61 pubmed 出版商 |
| Davis S, Collier L, Foran E, Leonardo C, Ajmo C, Pennypacker K. Neuroprotective activity of leukemia inhibitory factor is relayed through myeloid zinc finger-1 in a rat model of stroke. Metab Brain Dis. 2019;34:631-640 pubmed 出版商 |
| Chen J, Yang T, Cheng T, Hsiao T, Chang P, Leu J, et al. Modified Sijunzi decoction can alleviate cisplatin-induced toxicity and prolong the survival time of cachectic mice by recovering muscle atrophy. J Ethnopharmacol. 2019;233:47-55 pubmed 出版商 |
| Oh S, Sung Y, Kim I, Sim C, Lee J, Baek M, et al. Novel Compound Heterozygote Mutation in IL10RA in a Patient With Very Early-Onset Inflammatory Bowel Disease. Inflamm Bowel Dis. 2019;25:498-509 pubmed 出版商 |
| Yang C, Gopula B, Liang J, Li J, Chen S, Lee Y, et al. Novel AR-12 derivatives, P12-23 and P12-34, inhibit flavivirus replication by blocking host de novo pyrimidine biosynthesis. Emerg Microbes Infect. 2018;7:187 pubmed 出版商 |
| Davis S, Collier L, Goodwin S, Lukins D, Powell D, Pennypacker K. Efficacy of leukemia inhibitory factor as a therapeutic for permanent large vessel stroke differs among aged male and female rats. Brain Res. 2019;1707:62-73 pubmed 出版商 |
| Harun Or Rashid M, Inman D. Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma. J Neuroinflammation. 2018;15:313 pubmed 出版商 |
| Zhu M, Tang H, Tang X, Ma X, Guo D, Chen F. BMAL1 suppresses ROS-induced endothelial-to-mesenchymal transition and atherosclerosis plaque progression via BMP signaling. Am J Transl Res. 2018;10:3150-3161 pubmed |
| Di K, Lomeli N, Bota D, Das B. Magmas inhibition as a potential treatment strategy in malignant glioma. J Neurooncol. 2019;141:267-276 pubmed 出版商 |
| Zhang C, Lai M, Pedler M, Johnson V, Adams R, Petrash J, et al. Endothelial Cell-Specific Inactivation of TSPAN12 (Tetraspanin 12) Reveals Pathological Consequences of Barrier Defects in an Otherwise Intact Vasculature. Arterioscler Thromb Vasc Biol. 2018;38:2691-2705 pubmed 出版商 |
| Davis S, Collier L, Winford E, Leonardo C, Ajmo C, Foran E, et al. Leukemia inhibitory factor modulates the peripheral immune response in a rat model of emergent large vessel occlusion. J Neuroinflammation. 2018;15:288 pubmed 出版商 |
| Halu A, Wang J, Iwata H, Mojcher A, Abib A, Singh S, et al. Context-enriched interactome powered by proteomics helps the identification of novel regulators of macrophage activation. elife. 2018;7: pubmed 出版商 |
| Lananna B, Nadarajah C, Izumo M, Cedeno M, Xiong D, Dimitry J, et al. Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1. Cell Rep. 2018;25:1-9.e5 pubmed 出版商 |
| Yang C, Stueve T, Yan C, Rhie S, Mullen D, Luo J, et al. Positional integration of lung adenocarcinoma susceptibility loci with primary human alveolar epithelial cell epigenomes. Epigenomics. 2018;10:1167-1187 pubmed 出版商 |
| Going C, Tailor D, Kumar V, Birk A, Pandrala M, Rice M, et al. Quantitative Proteomic Profiling Reveals Key Pathways in the Anticancer Action of Methoxychalcone Derivatives in Triple Negative Breast Cancer. J Proteome Res. 2018;17:3574-3585 pubmed 出版商 |
| Zhao K, Shen C, Li L, Wu H, Xing G, Dong Z, et al. Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing LRP4. J Neurosci. 2018;38:8860-8873 pubmed 出版商 |
| Lee B, Stowe I, Gupta A, Kornfeld O, Roose Girma M, Anderson K, et al. Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation. J Exp Med. 2018;215:2279-2288 pubmed 出版商 |
| Vicente M, Almeida M, Bicego K, Carrettiero D, Gargaglioni L. Hypercapnic and Hypoxic Respiratory Response During Wakefulness and Sleep in a Streptozotocin Model of Alzheimer's Disease in Rats. J Alzheimers Dis. 2018;65:1159-1174 pubmed 出版商 |
| Li Z, Qian P, Shao W, Shi H, He X, Gogol M, et al. Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion. Cell Res. 2018;28:904-917 pubmed 出版商 |
| Lieberman O, McGuirt A, Mosharov E, Pigulevskiy I, Hobson B, Choi S, et al. Dopamine Triggers the Maturation of Striatal Spiny Projection Neuron Excitability during a Critical Period. Neuron. 2018;99:540-554.e4 pubmed 出版商 |
| Benhadjeba S, Edjekouane L, Sauvé K, Carmona E, Tremblay A. Feedback control of the CXCR7/CXCL11 chemokine axis by estrogen receptor α in ovarian cancer. Mol Oncol. 2018;12:1689-1705 pubmed 出版商 |
| Chiu H, Chiu H, Yang C, Lee Y, Chiu F, Kuo H, et al. Inhibition of Japanese encephalitis virus infection by the host zinc-finger antiviral protein. PLoS Pathog. 2018;14:e1007166 pubmed 出版商 |
| Laukka T, Myllykoski M, Looper R, Koivunen P. Cancer-associated 2-oxoglutarate analogues modify histone methylation by inhibiting histone lysine demethylases. J Mol Biol. 2018;430:3081-3092 pubmed 出版商 |
| Li T, Wu Y, Tsai H, Sun C, Wu Y, Wu H, et al. Intrahepatic hepatitis B virus large surface antigen induces hepatocyte hyperploidy via failure of cytokinesis. J Pathol. 2018;245:502-513 pubmed 出版商 |
| Motzko Soares A, Vizin R, Martins T, Hungaro A, Sato J, Almeida M, et al. Thermoregulatory profile of neurodegeneration-induced dementia of the Alzheimer's type using intracerebroventricular streptozotocin in rats. Acta Physiol (Oxf). 2018;224:e13084 pubmed 出版商 |
| Maddalena A, Dell Aquila F, Giovannelli P, Tiberi P, Wanderlingh L, Montefusco S, et al. High-Throughput Screening Identifies Kinase Inhibitors That Increase Dual Adeno-Associated Viral Vector Transduction In Vitro and in Mouse Retina. Hum Gene Ther. 2018;29:886-901 pubmed 出版商 |
| Zhou R, Xu T, Liu X, Chen Y, Kong D, Tian H, et al. Activation of spinal dorsal horn P2Y13 receptors can promote the expression of IL-1β and IL-6 in rats with diabetic neuropathic pain. J Pain Res. 2018;11:615-628 pubmed 出版商 |
| Ferriero R, Nusco E, De Cegli R, Carissimo A, Manco G, Brunetti Pierri N. Pyruvate dehydrogenase complex and lactate dehydrogenase are targets for therapy of acute liver failure. J Hepatol. 2018;69:325-335 pubmed 出版商 |
| Tsai M, Wang Y, Lai Y, Tsou H, Liou G, Ko J, et al. Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice. Toxicol Lett. 2018;290:97-109 pubmed 出版商 |
| Lee B, Mirrashidi K, Stowe I, Kummerfeld S, Watanabe C, Haley B, et al. ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages. Sci Rep. 2018;8:3788 pubmed 出版商 |
| Das V, Kc R, Li X, Varma D, Qiu S, Kroin J, et al. Pharmacological targeting of the mammalian clock reveals a novel analgesic for osteoarthritis-induced pain. Gene. 2018;655:1-12 pubmed 出版商 |
| Steiner C, Gevaert T, Ganzer R, De Ridder D, Neuhaus J. Comparative immunohistochemical characterization of interstitial cells in the urinary bladder of human, guinea pig and pig. Histochem Cell Biol. 2018;149:491-501 pubmed 出版商 |
| Ye R, Gordillo R, Shao M, Onodera T, Chen Z, Chen S, et al. Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity. J Clin Invest. 2018;128:1178-1189 pubmed 出版商 |
| Itoh S, Mizuno K, Aikawa M, Aikawa E. Dimerization of sortilin regulates its trafficking to extracellular vesicles. J Biol Chem. 2018;293:4532-4544 pubmed 出版商 |
| Kress G, Liao F, Dimitry J, Cedeno M, Fitzgerald G, Holtzman D, et al. Regulation of amyloid-β dynamics and pathology by the circadian clock. J Exp Med. 2018;215:1059-1068 pubmed 出版商 |
| Yu X, Stallone J, Heaps C, Han G. The activation of G protein-coupled estrogen receptor induces relaxation via cAMP as well as potentiates contraction via EGFR transactivation in porcine coronary arteries. PLoS ONE. 2018;13:e0191418 pubmed 出版商 |
| Maddalena A, Tornabene P, Tiberi P, Minopoli R, Manfredi A, Mutarelli M, et al. Triple Vectors Expand AAV Transfer Capacity in the Retina. Mol Ther. 2018;26:524-541 pubmed 出版商 |
| Nag S, Resnick A. Stabilization of hypoxia inducible factor by cobalt chloride can alter renal epithelial transport. Physiol Rep. 2017;5: pubmed 出版商 |
| Pol A, Renkema G, Tangerman A, Winkel E, Engelke U, de Brouwer A, et al. Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extraoral halitosis. Nat Genet. 2018;50:120-129 pubmed 出版商 |
| Cree B, Niu J, Hoi K, Zhao C, Caganap S, Henry R, et al. Clemastine rescues myelination defects and promotes functional recovery in hypoxic brain injury. Brain. 2017;: pubmed 出版商 |
| Boström J, Srámková Z, Salasova A, Johard H, Mahdessian D, Fedr R, et al. Comparative cell cycle transcriptomics reveals synchronization of developmental transcription factor networks in cancer cells. PLoS ONE. 2017;12:e0188772 pubmed 出版商 |
| Ullah K, Rosendahl A, Izzi V, Bergmann U, Pihlajaniemi T, Maki J, et al. Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-κB and p53 signaling pathways. Sci Rep. 2017;7:17220 pubmed 出版商 |
| Khan N, Muralidharan A, Smith M. Attenuation of the Infiltration of Angiotensin II Expressing CD3+ T-Cells and the Modulation of Nerve Growth Factor in Lumbar Dorsal Root Ganglia - A Possible Mechanism Underpinning Analgesia Produced by EMA300, An Angiotensin II Type 2 (AT2) Recepto. Front Mol Neurosci. 2017;10:389 pubmed 出版商 |
| Jongen J, van der Waals L, Trumpi K, Laoukili J, Peters N, Schenning van Schelven S, et al. Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability. Oncotarget. 2017;8:86296-86311 pubmed 出版商 |
| Mazzoni J, Smith J, Shahriar S, Cutforth T, Ceja B, Agalliu D. The Wnt Inhibitor Apcdd1 Coordinates Vascular Remodeling and Barrier Maturation of Retinal Blood Vessels. Neuron. 2017;96:1055-1069.e6 pubmed 出版商 |
| Ge Q, Zhang H, Hou J, Wan L, Cheng W, Wang X, et al. VEGF secreted by mesenchymal stem cells mediates the differentiation of endothelial progenitor cells into endothelial cells via paracrine mechanisms. Mol Med Rep. 2017;: pubmed 出版商 |
| Lai B, Zou J, Lin Z, Qu Z, Song A, Xu Y, et al. Haploinsufficiency of hnRNP U Changes Activity Pattern and Metabolic Rhythms. Am J Pathol. 2018;188:173-183 pubmed 出版商 |
| El Hassan A, Leung V, Kharfallah F, Guyot M, Allache R, Gros P, et al. Identification and characterization of a novel chemically induced allele at the planar cell polarity gene Vangl2. Mamm Genome. 2018;29:229-244 pubmed 出版商 |
| Zhao W, Pferdehirt L, Segatori L. Quantitatively Predictable Control of Cellular Protein Levels through Proteasomal Degradation. ACS Synth Biol. 2017;: pubmed 出版商 |
| Walters D, Arendt B, Tschumper R, Wu X, Jelinek D. Characterization and use of the novel human multiple myeloma cell line MC-B11/14 to study biological consequences of CRISPR-mediated loss of immunoglobulin A heavy chain. Exp Hematol. 2018;57:42-49.e1 pubmed 出版商 |
| Yoon H, Radulovic M, Walters G, Paulsen A, Drucker K, Starski P, et al. Protease activated receptor 2 controls myelin development, resiliency and repair. Glia. 2017;65:2070-2086 pubmed 出版商 |
| Niu J, Huang D, Zhou R, Yue M, Xu T, Yang J, et al. Activation of dorsal horn cannabinoid CB2 receptor suppresses the expression of P2Y12 and P2Y13 receptors in neuropathic pain rats. J Neuroinflammation. 2017;14:185 pubmed 出版商 |
| Nagami M, Ito Y, Nagasawa T. Phenethyl isothiocyanate protects against H2O2-induced insulin resistance in 3T3-L1 adipocytes. Biosci Biotechnol Biochem. 2017;81:2195-2203 pubmed 出版商 |
| Chiu H, Tsay Y, Hung S. Involvement of mTOR-autophagy in the selection of primitive mesenchymal stem cells in chitosan film 3-dimensional culture. Sci Rep. 2017;7:10113 pubmed 出版商 |
| Bohnsack J, Patel V, Morrow A. Ethanol Exposure Regulates Gabra1 Expression via Histone Deacetylation at the Promoter in Cultured Cortical Neurons. J Pharmacol Exp Ther. 2017;363:1-11 pubmed 出版商 |
| Noutsios G, Willis A, Ledford J, Chang E. Novel role of surfactant protein A in bacterial sinusitis. Int Forum Allergy Rhinol. 2017;7:897-903 pubmed 出版商 |
| Lin N, Messing A, Perng M. Characterization of a panel of monoclonal antibodies recognizing specific epitopes on GFAP. PLoS ONE. 2017;12:e0180694 pubmed 出版商 |
| Yoon H, Walters G, Paulsen A, Scarisbrick I. Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination. PLoS ONE. 2017;12:e0180697 pubmed 出版商 |
| Ambroz M, Matousková P, Skarka A, Zajdlova M, Žáková K, Skalova L. The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines. Molecules. 2017;22: pubmed 出版商 |
| Chang C, Lu C, Lin C, Martel J, Ko Y, Ojcius D, et al. Antrodia cinnamomea reduces obesity and modulates the gut microbiota in high-fat diet-fed mice. Int J Obes (Lond). 2018;42:231-243 pubmed 出版商 |
| Zagni C, Almeida L, Balan T, Martins M, Rosselli Murai L, Papagerakis P, et al. PTEN Mediates Activation of Core Clock Protein BMAL1 and Accumulation of Epidermal Stem Cells. Stem Cell Reports. 2017;9:304-314 pubmed 出版商 |
| Wu P, Wang J, Chen C, Chao K, Chang M, Chen W, et al. Early Passage Mesenchymal Stem Cells Display Decreased Radiosensitivity and Increased DNA Repair Activity. Stem Cells Transl Med. 2017;6:1504-1514 pubmed 出版商 |
| Balbaa M, Abdulmalek S, Khalil S. Oxidative stress and expression of insulin signaling proteins in the brain of diabetic rats: Role of Nigella sativa oil and antidiabetic drugs. PLoS ONE. 2017;12:e0172429 pubmed 出版商 |
| Pettersson H, Zarnegar B, Westin A, Persson V, Peuckert C, Jönsson J, et al. SLC10A4 regulates IgE-mediated mast cell degranulation in vitro and mast cell-mediated reactions in vivo. Sci Rep. 2017;7:1085 pubmed 出版商 |
| Frederick A, Goldsmith J, de Zavalía N, Amir S. Mapping the co-localization of the circadian proteins PER2 and BMAL1 with enkephalin and substance P throughout the rodent forebrain. PLoS ONE. 2017;12:e0176279 pubmed 出版商 |
| Wang X, Dasari S, Nowakowski G, Lazaridis K, Wieben E, Kadin M, et al. Retinoic acid receptor alpha drives cell cycle progression and is associated with increased sensitivity to retinoids in T-cell lymphoma. Oncotarget. 2017;8:26245-26255 pubmed 出版商 |
| Ho T, Lee C, Lu Z, Lane H, Tsai M, Ho I, et al. Effects of Electroacupuncture on Methamphetamine-Induced Behavioral Changes in Mice. Evid Based Complement Alternat Med. 2017;2017:5642708 pubmed 出版商 |
| Lee Y, Kim J, Oh K, Chung S. Fatty acid-binding protein 4 regulates fatty infiltration after rotator cuff tear by hypoxia-inducible factor 1 in mice. J Cachexia Sarcopenia Muscle. 2017;8:839-850 pubmed 出版商 |
| Raats D, Frenkel N, van Schelven S, Rinkes I, Laoukili J, Kranenburg O. CD95 ligand induces senescence in mismatch repair-deficient human colon cancer via chronic caspase-mediated induction of DNA damage. Cell Death Dis. 2017;8:e2669 pubmed 出版商 |
| Piccolo P, Annunziata P, Soria L, Attanasio S, Barbato A, Castello R, et al. Down-regulation of hepatocyte nuclear factor-4? and defective zonation in livers expressing mutant Z ?1-antitrypsin. Hepatology. 2017;66:124-135 pubmed 出版商 |
| Chen K, Hsieh M, Li Y, Lin Y, Lai H, Shieh M, et al. Study of poly-?-caprolactone membranes for pleurodesis. J Formos Med Assoc. 2017;116:880-887 pubmed 出版商 |
| Bilodeau S, Caron V, Gagnon J, Kuftedjian A, Tremblay A. A CK2-RNF4 interplay coordinates non-canonical SUMOylation and degradation of nuclear receptor FXR. J Mol Cell Biol. 2017;9:195-208 pubmed 出版商 |
| Giatromanolaki A, Liousia M, Arelaki S, Kalamida D, Pouliliou S, Mitrakas A, et al. Differential effect of hypoxia and acidity on lung cancer cell and fibroblast metabolism. Biochem Cell Biol. 2017;95:428-436 pubmed 出版商 |
| Wang X, Boddicker R, Dasari S, Sidhu J, Kadin M, Macon W, et al. Expression of p63 protein in anaplastic large cell lymphoma: implications for genetic subtyping. Hum Pathol. 2017;64:19-27 pubmed 出版商 |
| Sansone C, Galasso C, Orefice I, Nuzzo G, Luongo E, Cutignano A, et al. The green microalga Tetraselmis suecica reduces oxidative stress and induces repairing mechanisms in human cells. Sci Rep. 2017;7:41215 pubmed 出版商 |
| Pereira M, Ortolan L, Sercundes M, Debone D, Murillo O, Lima F, et al. Association of Heme Oxygenase 1 with Lung Protection in Malaria-Associated ALI/ARDS. Mediators Inflamm. 2016;2016:4158698 pubmed |
| Abdelbaset Ismail A, Pędziwiatr D, Schneider G, Niklinski J, Charkiewicz R, Moniuszko M, et al. Pituitary sex hormones enhance the pro‑metastatic potential of human lung cancer cells by downregulating the intracellular expression of heme oxygenase‑1. Int J Oncol. 2017;50:317-328 pubmed 出版商 |
| Lin Y, Chao T, Yeh C, Roffler S, Kannagi R, Yang R. Endothelial SCUBE2 Interacts With VEGFR2 and Regulates VEGF-Induced Angiogenesis. Arterioscler Thromb Vasc Biol. 2017;37:144-155 pubmed 出版商 |
| Chen H, Yeh Y, Liu C, Wu Y, Lo F, Tang M, et al. DDR1 promotes E-cadherin stability via inhibition of integrin-β1-Src activation-mediated E-cadherin endocytosis. Sci Rep. 2016;6:36336 pubmed 出版商 |
| Getun I, Wu Z, Fallahi M, Ouizem S, Liu Q, Li W, et al. Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hot Spots. Mol Cell Biol. 2017;37: pubmed 出版商 |
| Iwata H, Goettsch C, Sharma A, Ricchiuto P, Goh W, Halu A, et al. PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation. Nat Commun. 2016;7:12849 pubmed 出版商 |
| Zhou T, Rivera J, Bhosle V, Lahaie I, Shao Z, Tahiri H, et al. Choroidal Involution Is Associated with a Progressive Degeneration of the Outer Retinal Function in a Model of Retinopathy of Prematurity: Early Role for IL-1?. Am J Pathol. 2016;186:3100-3116 pubmed 出版商 |
| Di K, Lomeli N, Wood S, Vanderwal C, Bota D. Mitochondrial Lon is over-expressed in high-grade gliomas, and mediates hypoxic adaptation: potential role of Lon as a therapeutic target in glioma. Oncotarget. 2016;7:77457-77467 pubmed 出版商 |
| Pradhan S, Mahajan D, Kaur P, Pandey N, Sharma C, Srivastava T. Scriptaid overcomes hypoxia-induced cisplatin resistance in both wild-type and mutant p53 lung cancer cells. Oncotarget. 2016;7:71841-71855 pubmed 出版商 |
| Dumbell R, Leliavski A, Matveeva O, Blaum C, Tsang A, Oster H. Dissociation of Molecular and Endocrine Circadian Rhythms in Male Mice Lacking Bmal1 in the Adrenal Cortex. Endocrinology. 2016;157:4222-4233 pubmed |
| Hu Y, Su H, Liu C, Wang Z, Huang L, Wang Q, et al. DEPTOR is a direct NOTCH1 target that promotes cell proliferation and survival in T-cell leukemia. Oncogene. 2017;36:1038-1047 pubmed 出版商 |
| Erdogan S, Doganlar O, Doganlar Z, Serttas R, Türkekul K, Dibirdik I, et al. The flavonoid apigenin reduces prostate cancer CD44(+) stem cell survival and migration through PI3K/Akt/NF-?B signaling. Life Sci. 2016;162:77-86 pubmed 出版商 |
| Yoon H, Scarisbrick I. Kallikrein-related peptidase 6 exacerbates disease in an autoimmune model of multiple sclerosis. Biol Chem. 2016;397:1277-1286 pubmed 出版商 |
| Vanas V, Haigl B, Stockhammer V, Sutterlüty Fall H. MicroRNA-21 Increases Proliferation and Cisplatin Sensitivity of Osteosarcoma-Derived Cells. PLoS ONE. 2016;11:e0161023 pubmed 出版商 |
| Leinonen H, Rossi M, Salo A, Tiainen P, Hyvärinen J, Pitkänen M, et al. Lack of P4H-TM in mice results in age-related retinal and renal alterations. Hum Mol Genet. 2016;25:3810-3823 pubmed 出版商 |
| Sato T, Ito Y, Nagasawa T. Regulatory effects of the L-lysine metabolites, L-2-aminoadipic acid and L-pipecolic acid, on protein turnover in C2C12 myotubes. Biosci Biotechnol Biochem. 2016;80:2168-2175 pubmed 出版商 |
| Wong A, Hristova E, Ahlskog N, Tasse L, Ngsee J, Chudalayandi P, et al. Aberrant Subcellular Dynamics of Sigma-1 Receptor Mutants Underlying Neuromuscular Diseases. Mol Pharmacol. 2016;90:238-53 pubmed 出版商 |
| Ekser B, Mangus R, Kubal C, Fridell J, Powelson J, Nagaraju S, et al. Recurrence of Hyperoxaluria and Kidney Disease after Combined Intestine-Kidney Transplantation for Enteric Hyperoxaluria. Am J Nephrol. 2016;44:85-91 pubmed 出版商 |
| Baradaran Heravi A, Balgi A, Zimmerman C, Choi K, Shidmoossavee F, Tan J, et al. Novel small molecules potentiate premature termination codon readthrough by aminoglycosides. Nucleic Acids Res. 2016;44:6583-98 pubmed 出版商 |
| Lee M, Huang H, Chang T, Huang H, Hsieh S, Chen Y, et al. Genome-wide analysis of HIF-2? chromatin binding sites under normoxia in human bronchial epithelial cells (BEAS-2B) suggests its diverse functions. Sci Rep. 2016;6:29311 pubmed 出版商 |
| Xu Y, Li F, Zalzala M, Xu J, Gonzalez F, Adorini L, et al. Farnesoid X receptor activation increases reverse cholesterol transport by modulating bile acid composition and cholesterol absorption in mice. Hepatology. 2016;64:1072-85 pubmed 出版商 |
| Goettsch C, Hutcheson J, Hagita S, Rogers M, Creager M, Pham T, et al. A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification. Atherosclerosis. 2016;251:109-118 pubmed 出版商 |
| Matsumoto C, Almeida L, Guimarães D, Martins M, Papagerakis P, Papagerakis S, et al. PI3K-PTEN dysregulation leads to mTOR-driven upregulation of the core clock gene BMAL1 in normal and malignant epithelial cells. Oncotarget. 2016;7:42393-42407 pubmed 出版商 |
| Tsai W, Yeh P, Tsai C, Ting C, Chiu Y, Tao M, et al. Efficient programming of human mesenchymal stem cell-derived hepatocytes by epigenetic regulations. J Gastroenterol Hepatol. 2017;32:261-269 pubmed 出版商 |
| Bhoopathi P, Lee N, Pradhan A, Shen X, Das S, Sarkar D, et al. mda-7/IL-24 Induces Cell Death in Neuroblastoma through a Novel Mechanism Involving AIF and ATM. Cancer Res. 2016;76:3572-82 pubmed 出版商 |
| Pastore N, Brady O, Diab H, Martina J, Sun L, Huynh T, et al. TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages. Autophagy. 2016;12:1240-58 pubmed 出版商 |
| Radulovic M, Yoon H, Wu J, Mustafa K, Scarisbrick I. Targeting the thrombin receptor modulates inflammation and astrogliosis to improve recovery after spinal cord injury. Neurobiol Dis. 2016;93:226-42 pubmed 出版商 |
| Boothe T, Lim G, Cen H, Skovsø S, Piske M, Li S, et al. Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells. Mol Metab. 2016;5:366-378 pubmed 出版商 |
| Lai C, Chen H, Tsai T, Chu T, Yang S, Chong K, et al. Sexually Dimorphic Expression of eGFP Transgene in the Akr1A1 Locus of Mouse Liver Regulated by Sex Hormone-Related Epigenetic Remodeling. Sci Rep. 2016;6:24023 pubmed 出版商 |
| Xu J, Xu Y, Li Y, Jadhav K, You M, Yin L, et al. Carboxylesterase 1 Is Regulated by Hepatocyte Nuclear Factor 4? and Protects Against Alcohol- and MCD diet-induced Liver Injury. Sci Rep. 2016;6:24277 pubmed 出版商 |
| Acharya M, Sokolovska A, Tam J, Conway K, Stefani C, Raso F, et al. αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells. Nat Commun. 2016;7:10917 pubmed 出版商 |
| Naik E, Dixit V. Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity. J Immunol. 2016;196:3438-51 pubmed 出版商 |
| Hong M, Nam K, Kim K, Kim S, Kim I. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016;21:485-97 pubmed 出版商 |
| Andreev E, Brosseau N, Carmona E, Mes Masson A, Ramotar D. The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin. Sci Rep. 2016;6:20508 pubmed 出版商 |
| Gosejacob D, Jäger P, Vom Dorp K, Frejno M, Carstensen A, Köhnke M, et al. Ceramide Synthase 5 Is Essential to Maintain C16:0-Ceramide Pools and Contributes to the Development of Diet-induced Obesity. J Biol Chem. 2016;291:6989-7003 pubmed 出版商 |
| Yoon H, Kleven A, Paulsen A, Kleppe L, Wu J, Ying Z, et al. Interplay between exercise and dietary fat modulates myelinogenesis in the central nervous system. Biochim Biophys Acta. 2016;1862:545-555 pubmed 出版商 |
| Maj M, Hoermann G, Rasul S, Base W, Wagner L, Attems J. The Microtubule-Associated Protein Tau and Its Relevance for Pancreatic Beta Cells. J Diabetes Res. 2016;2016:1964634 pubmed 出版商 |
| Westwell Roper C, Denroche H, Ehses J, Verchere C. Differential Activation of Innate Immune Pathways by Distinct Islet Amyloid Polypeptide (IAPP) Aggregates. J Biol Chem. 2016;291:8908-17 pubmed 出版商 |
| Bohnsack J, Carlson S, Morrow A. Differential regulation of synaptic and extrasynaptic α4 GABA(A) receptor populations by protein kinase A and protein kinase C in cultured cortical neurons. Neuropharmacology. 2016;105:124-132 pubmed 出版商 |
| Davis S, Collier L, Leonardo C, Seifert H, Ajmo C, Pennypacker K. Leukemia Inhibitory Factor Protects Neurons from Ischemic Damage via Upregulation of Superoxide Dismutase 3. Mol Neurobiol. 2017;54:608-622 pubmed 出版商 |
| Lee S, Frattini V, Bansal M, Castano A, Sherman D, Hutchinson K, et al. An ID2-dependent mechanism for VHL inactivation in cancer. Nature. 2016;529:172-7 pubmed 出版商 |
| Cerqueira F, Chausse B, Baranovski B, Liesa M, Lewis E, Shirihai O, et al. Diluted serum from calorie-restricted animals promotes mitochondrial β-cell adaptations and protect against glucolipotoxicity. FEBS J. 2016;283:822-33 pubmed 出版商 |
| Lee K, Hsieh Y, Yang Y, Chan C, Huang Y, Lin H. Aliskiren Reduces Hepatic steatosis and Epididymal Fat Mass and Increases Skeletal Muscle Insulin Sensitivity in High-Fat Diet-Fed Mice. Sci Rep. 2016;6:18899 pubmed 出版商 |
| Kral R, Doriguzzi A, Mayer C, Krenbek D, Setinek U, Sutterlüty Fall H. Differential Effects of Variations at Codon 106 on Sprouty2 Functions in Lung Cancer-Derived Cells. J Cell Biochem. 2016;117:1822-32 pubmed 出版商 |
| Yu C, Liang J, Li J, Lee Y, Chang B, Su C, et al. Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins. PLoS Pathog. 2015;11:e1005350 pubmed 出版商 |
| Wang T, Lin Y, Lo C, Tang C, Teng C, Chao W, et al. Oncogenic roles of carbonic anhydrase 8 in human osteosarcoma cells. Tumour Biol. 2016;37:7989-8005 pubmed 出版商 |
| Laukka T, Mariani C, Ihantola T, Cao J, Hokkanen J, Kaelin W, et al. Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes. J Biol Chem. 2016;291:4256-65 pubmed 出版商 |
| Vannuvel K, Van Steenbrugge M, Demazy C, Ninane N, Fattaccioli A, Fransolet M, et al. Effects of a Sublethal and Transient Stress of the Endoplasmic Reticulum on the Mitochondrial Population. J Cell Physiol. 2016;231:1913-31 pubmed 出版商 |
| Sorrentino N, Maffia V, Strollo S, Cacace V, Romagnoli N, Manfredi A, et al. A Comprehensive Map of CNS Transduction by Eight Recombinant Adeno-associated Virus Serotypes Upon Cerebrospinal Fluid Administration in Pigs. Mol Ther. 2016;24:276-286 pubmed 出版商 |
| Suriben R, Kaihara K, Paolino M, Reichelt M, Kummerfeld S, Modrusan Z, et al. β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1. Cell. 2015;163:1457-67 pubmed 出版商 |
| Yang Y, Jin Y, Du W. Programmed cell death 2 functions as a tumor suppressor in osteosarcoma. Int J Clin Exp Pathol. 2015;8:10894-900 pubmed |
| Fossati S, Giannoni P, Solesio M, Cocklin S, Cabrera E, Ghiso J, et al. The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain. Neurobiol Dis. 2016;86:29-40 pubmed 出版商 |
| Cheng Y, Young G, Lin J, Jang H, Chen C, Nong J, et al. Activation of AMP-Activated Protein Kinase by Adenine Alleviates TNF-Alpha-Induced Inflammation in Human Umbilical Vein Endothelial Cells. PLoS ONE. 2015;10:e0142283 pubmed 出版商 |
| Perelis M, Marcheva B, Ramsey K, Schipma M, Hutchison A, Taguchi A, et al. Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretion. Science. 2015;350:aac4250 pubmed 出版商 |
| Lin C, Cheng Y, Li H, Chiu P, Chang Y, Ho Y, et al. Amyloid-β suppresses AMP-activated protein kinase (AMPK) signaling and contributes to α-synuclein-induced cytotoxicity. Exp Neurol. 2016;275 Pt 1:84-98 pubmed 出版商 |
| Lin C, Chen Y, Lin C, Chen Y, Lo G, Lee P, et al. Amiodarone as an autophagy promoter reduces liver injury and enhances liver regeneration and survival in mice after partial hepatectomy. Sci Rep. 2015;5:15807 pubmed 出版商 |
| Weng W, Leung W, Pang Y, Hsu H. Lauric acid can improve the sensitization of Cetuximab in KRAS/BRAF mutated colorectal cancer cells by retrievable microRNA-378 expression. Oncol Rep. 2016;35:107-16 pubmed 出版商 |
| Karsikas S, Myllymäki M, Heikkilä M, Sormunen R, Kivirikko K, Myllyharju J, et al. HIF-P4H-2 deficiency protects against skeletal muscle ischemia-reperfusion injury. J Mol Med (Berl). 2016;94:301-10 pubmed 出版商 |
| Shi C, Huang X, Zhang B, Zhu D, Luo H, Lu Q, et al. The Inhibition of Heat Shock Protein 90 Facilitates the Degradation of Poly-Alanine Expanded Poly (A) Binding Protein Nuclear 1 via the Carboxyl Terminus of Heat Shock Protein 70-Interacting Protein. PLoS ONE. 2015;10:e0138936 pubmed 出版商 |
| Qiu Q, Yang C, Xiong W, Tahiri H, Payeur M, Superstein R, et al. SYK is a target of lymphocyte-derived microparticles in the induction of apoptosis of human retinoblastoma cells. Apoptosis. 2015;20:1613-22 pubmed 出版商 |
| Cox J, Abdelrahman Y, Peters J, Naher N, Belland R. Chlamydia trachomatis utilizes the mammalian CLA1 lipid transporter to acquire host phosphatidylcholine essential for growth. Cell Microbiol. 2016;18:305-18 pubmed 出版商 |
| Koukourakis M, Kalamida D, Giatromanolaki A, Zois C, Sivridis E, Pouliliou S, et al. Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines. PLoS ONE. 2015;10:e0137675 pubmed 出版商 |
| Sato T, Ito Y, Nagasawa T. Dietary L-Lysine Suppresses Autophagic Proteolysis and Stimulates Akt/mTOR Signaling in the Skeletal Muscle of Rats Fed a Low-Protein Diet. J Agric Food Chem. 2015;63:8192-8 pubmed 出版商 |
| Wu L, Zhang Z, Pan X, Wang Z. Expression and contribution of the HIF-1α/VEGF signaling pathway to luteal development and function in pregnant rats. Mol Med Rep. 2015;12:7153-9 pubmed 出版商 |
| Radulovic M, Yoon H, Wu J, Mustafa K, Fehlings M, Scarisbrick I. Genetic targeting of protease activated receptor 2 reduces inflammatory astrogliosis and improves recovery of function after spinal cord injury. Neurobiol Dis. 2015;83:75-89 pubmed 出版商 |
| Sato T, Ito Y, Nagasawa T. Attenuation of autophagic-proteolysis in C2C12 cells by saccharopine. Mol Cell Biochem. 2015;410:93-100 pubmed 出版商 |
| Lin C, Huang W, Li H, Huang C, Hsieh S, Lai C, et al. Hydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells. Chem Biol Interact. 2015;240:12-21 pubmed 出版商 |
| Juhász T, Szentléleky E, Somogyi C, Takács R, Dobrosi N, Engler M, et al. Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Pathway Is Induced by Mechanical Load and Reduces the Activity of Hedgehog Signaling in Chondrogenic Micromass Cell Cultures. Int J Mol Sci. 2015;16:17344-67 pubmed 出版商 |
| Lim G, Albrecht T, Piske M, Sarai K, Lee J, Ramshaw H, et al. 14-3-3ζ coordinates adipogenesis of visceral fat. Nat Commun. 2015;6:7671 pubmed 出版商 |
| Bamidele A, Kremer K, Hirsova P, Clift I, Gores G, Billadeau D, et al. IQGAP1 promotes CXCR4 chemokine receptor function and trafficking via EEA-1+ endosomes. J Cell Biol. 2015;210:257-72 pubmed 出版商 |
| Lin C, Jan M, Kuo J. Exploring MicroRNA Expression Profiles Related to the mTOR Signaling Pathway in Mouse Embryonic Fibroblast Cells Treated with Polyethylenimine. Mol Pharm. 2015;12:2858-68 pubmed 出版商 |
| Yang C, Fischer KeÅ¡o R, Schlechter T, Ströbel P, Marx A, Hofmann I. Plakophilin 1-deficient cells upregulate SPOCK1: implications for prostate cancer progression. Tumour Biol. 2015;36:9567-77 pubmed 出版商 |
| Sasaki Y, Ohta M, Desai D, Figueiredo J, Whelan M, Sugano T, et al. Angiopoietin Like Protein 2 (ANGPTL2) Promotes Adipose Tissue Macrophage and T lymphocyte Accumulation and Leads to Insulin Resistance. PLoS ONE. 2015;10:e0131176 pubmed 出版商 |
| Yang J, Lin C, Chuang C, Su S, Lin S, Yang S. Carbonic anhydrase IX overexpression regulates the migration and progression in oral squamous cell carcinoma. Tumour Biol. 2015;36:9517-24 pubmed 出版商 |
| Smith B, Simpson D, Miller R, Erdman J, O Brien W. Contrast Ultrasound Imaging Does Not Affect Heat Shock Protein 70 Expression in Cholesterol-Fed Rabbit Aorta. J Ultrasound Med. 2015;34:1209-16 pubmed 出版商 |
| Miki Y, Akimoto J, Moritake K, Hironaka C, Fujiwara Y. Photodynamic therapy using talaporfin sodium induces concentration-dependent programmed necroptosis in human glioblastoma T98G cells. Lasers Med Sci. 2015;30:1739-45 pubmed 出版商 |
| Chang C, Lin C, Lu C, Martel J, Ko Y, Ojcius D, et al. Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota. Nat Commun. 2015;6:7489 pubmed 出版商 |
| Xu Y, Zalzala M, Xu J, Li Y, Yin L, Zhang Y. A metabolic stress-inducible miR-34a-HNF4α pathway regulates lipid and lipoprotein metabolism. Nat Commun. 2015;6:7466 pubmed 出版商 |
| Billeter A, Galbraith N, Walker S, Lawson C, Gardner S, Sarojini H, et al. TRPA1 mediates the effects of hypothermia on the monocyte inflammatory response. Surgery. 2015;158:646-54 pubmed 出版商 |
| Viale Bouroncle S, Klingelhöffer C, Ettl T, Morsczeck C. The AKT signaling pathway sustains the osteogenic differentiation in human dental follicle cells. Mol Cell Biochem. 2015;406:199-204 pubmed 出版商 |
| Zhang Z, Pang X, Tang Z, Yin D, Wang Z. Overexpression of hypoxia-inducible factor prolyl hydoxylase-2 attenuates hypoxia-induced vascular endothelial growth factor expression in luteal cells. Mol Med Rep. 2015;12:3809-3814 pubmed 出版商 |
| Li H, Lu F, Hung H, Liu G, Lai T, Lin C. Humic Acid Increases Amyloid β-Induced Cytotoxicity by Induction of ER Stress in Human SK-N-MC Neuronal Cells. Int J Mol Sci. 2015;16:10426-42 pubmed 出版商 |
| Doriguzzi A, Haigl B, Gsur A, Sutterlüty Fall H. The increased Sprouty4 expression in response to serum is transcriptionally controlled by Specific protein 1. Int J Biochem Cell Biol. 2015;64:220-8 pubmed 出版商 |
| Wang M, Lin S, Hou Y, Chen Y. α-Naphthoflavone Increases Lipid Accumulation in Mature Adipocytes and Enhances Adipocyte-Stimulated Endothelial Tube Formation. Nutrients. 2015;7:3166-83 pubmed 出版商 |
| Yen J, Lin L, Chen M, Sarang Z, Leong P, Chang I, et al. The metastatic tumor antigen 1-transglutaminase-2 pathway is involved in self-limitation of monosodium urate crystal-induced inflammation by upregulating TGF-β1. Arthritis Res Ther. 2015;17:65 pubmed 出版商 |
| Kao Y, Chang B, Liang J, Tsai H, Lee Y, Lin R, et al. Japanese encephalitis virus nonstructural protein NS5 interacts with mitochondrial trifunctional protein and impairs fatty acid β-oxidation. PLoS Pathog. 2015;11:e1004750 pubmed 出版商 |
| Bonora M, Wieckowsk M, Chinopoulos C, Kepp O, Kroemer G, Galluzzi L, et al. Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition. Oncogene. 2015;34:1608 pubmed 出版商 |
| Matteucci C, Minutolo A, Marino Merlo F, Grelli S, Frezza C, Mastino A, et al. Characterization of the enhanced apoptotic response to azidothymidine by pharmacological inhibition of NF-kB. Life Sci. 2015;127:90-7 pubmed 出版商 |
| Wen J, Hanna C, Martell S, Leung P, Lewis S, Robinson W, et al. Functional consequences of copy number variants in miscarriage. Mol Cytogenet. 2015;8:6 pubmed 出版商 |
| Capo Chichi J, Boissel S, Brustein E, Pickles S, Fallet Bianco C, Nassif C, et al. Disruption of CLPB is associated with congenital microcephaly, severe encephalopathy and 3-methylglutaconic aciduria. J Med Genet. 2015;52:303-11 pubmed 出版商 |
| Yoon H, Radulovic M, Drucker K, Wu J, Scarisbrick I. The thrombin receptor is a critical extracellular switch controlling myelination. Glia. 2015;63:846-59 pubmed 出版商 |
| Chong K, Hsu C, Hung T, Hu H, Huang T, Wang T, et al. Wnt pathway activation and ABCB1 expression account for attenuation of proteasome inhibitor-mediated apoptosis in multidrug-resistant cancer cells. Cancer Biol Ther. 2015;16:149-59 pubmed 出版商 |
| Peng C, Lin Y, Chen K, Chyau C, Peng R. Antrodan, a β-glucan obtained from Antrodia cinnamomea mycelia, is beneficial to benign prostate hyperplasia. Food Funct. 2015;6:635-45 pubmed 出版商 |
| Taher C, Frisk G, Fuentes S, Religa P, Costa H, Assinger A, et al. High prevalence of human cytomegalovirus in brain metastases of patients with primary breast and colorectal cancers. Transl Oncol. 2014;7:732-40 pubmed 出版商 |
| Lin S, Chiu F, Wang Y, Yen M, Kao S, Hung S. RB maintains quiescence and prevents premature senescence through upregulation of DNMT1 in mesenchymal stromal cells. Stem Cell Reports. 2014;3:975-86 pubmed 出版商 |
| Hsin C, Chen M, Tang C, Lin H, Chou M, Lin C, et al. High level of plasma matrix metalloproteinase-11 is associated with clinicopathological characteristics in patients with oral squamous cell carcinoma. PLoS ONE. 2014;9:e113129 pubmed 出版商 |
| Pan W, Chen Y, Hsu H, Chen W. Antimicrobial peptide GW-H1-induced apoptosis of human gastric cancer AGS cell line is enhanced by suppression of autophagy. Mol Cell Biochem. 2015;400:77-86 pubmed 出版商 |
| Liu Y, Shim E, Crespo Mejias Y, Nguyen P, Gibbons A, Liu D, et al. Cardiomyocytes are Protected from Antiretroviral Nucleoside Analog-Induced Mitochondrial Toxicity by Overexpression of PGC-1α. Cardiovasc Toxicol. 2015;15:224-31 pubmed 出版商 |
| Chan M, Lim G, Skovsø S, Yang Y, Albrecht T, Alejandro E, et al. Effects of insulin on human pancreatic cancer progression modeled in vitro. BMC Cancer. 2014;14:814 pubmed 出版商 |
| Lajud S, Nagda D, Yamashita T, Zheng J, Tanaka N, Abuzeid W, et al. Dual disruption of DNA repair and telomere maintenance for the treatment of head and neck cancer. Clin Cancer Res. 2014;20:6465-78 pubmed 出版商 |
| Kokontis J, Lin H, Jiang S, Lin C, Fukuchi J, Hiipakka R, et al. Androgen suppresses the proliferation of androgen receptor-positive castration-resistant prostate cancer cells via inhibition of Cdk2, CyclinA, and Skp2. PLoS ONE. 2014;9:e109170 pubmed 出版商 |
| Fischer KeÅ¡o R, Breuninger S, Hofmann S, Henn M, Röhrig T, Ströbel P, et al. Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins. Mol Cell Biol. 2014;34:4244-56 pubmed 出版商 |
| Naik E, Webster J, DeVoss J, Liu J, Suriben R, Dixit V. Regulation of proximal T cell receptor signaling and tolerance induction by deubiquitinase Usp9X. J Exp Med. 2014;211:1947-55 pubmed 出版商 |
| Qin Q, Xie H, Wise S, Browning C, Thompson K, Holmes A, et al. Homologous recombination repair signaling in chemical carcinogenesis: prolonged particulate hexavalent chromium exposure suppresses the Rad51 response in human lung cells. Toxicol Sci. 2014;142:117-25 pubmed 出版商 |
| Yang N, Song T, Chang Y, Chen M, Hu M. Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells. Biogerontology. 2015;16:31-42 pubmed 出版商 |
| Hung Y, Hung S, Wu Y, Wong L, Lai M, Shih Y, et al. Soluble epoxide hydrolase activity regulates inflammatory responses and seizure generation in two mouse models of temporal lobe epilepsy. Brain Behav Immun. 2015;43:118-29 pubmed 出版商 |
| Dill McFarland K, Neil K, Zeng A, Sprenger R, Kurtz C, Suen G, et al. Hibernation alters the diversity and composition of mucosa-associated bacteria while enhancing antimicrobial defence in the gut of 13-lined ground squirrels. Mol Ecol. 2014;23:4658-69 pubmed 出版商 |
| Di K, Keir S, Alexandru Abrams D, Gong X, Nguyen H, Friedman H, et al. Profiling Hsp90 differential expression and the molecular effects of the Hsp90 inhibitor IPI-504 in high-grade glioma models. J Neurooncol. 2014;120:473-81 pubmed 出版商 |
| Benayoun B, Pollina E, Ucar D, Mahmoudi S, Karra K, Wong E, et al. H3K4me3 breadth is linked to cell identity and transcriptional consistency. Cell. 2014;158:673-88 pubmed 出版商 |
| Lin C, Jan M, Kuo J. Autophagy-related gene expression analysis of wild-type and atg5 gene knockout mouse embryonic fibroblast cells treated with polyethylenimine. Mol Pharm. 2014;11:3002-8 pubmed 出版商 |
| Bohr M, Brooks A, Kurtz C. Hibernation induces immune changes in the lung of 13-lined ground squirrels (Ictidomys tridecemlineatus). Dev Comp Immunol. 2014;47:178-84 pubmed 出版商 |
| Vande Walle L, Van Opdenbosch N, Jacques P, Fossoul A, Verheugen E, Vogel P, et al. Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis. Nature. 2014;512:69-73 pubmed 出版商 |
| Chen C, Lin J, Cheng Y, Kuo C, Huang C, Kao S, et al. Amelioration of LPS-induced inflammation response in microglia by AMPK activation. Biomed Res Int. 2014;2014:692061 pubmed 出版商 |
| Wu C, Lin K, Teng C, Huang A, Chen Y, Yen M, et al. Chalcone derivatives inhibit human platelet aggregation and inhibit growth in human bladder cancer cells. Biol Pharm Bull. 2014;37:1191-8 pubmed |
| Lin K, Huang A, Lin C, Chang C, Hsu W, Hour T, et al. Anti-cancer effects of ursane triterpenoid as a single agent and in combination with cisplatin in bladder cancer. Eur J Pharmacol. 2014;740:742-51 pubmed 出版商 |
| Chung P, Chi L, Chen C, Liang C, Lin C, Chang Y, et al. MicroRNA-205 targets tight junction-related proteins during urothelial cellular differentiation. Mol Cell Proteomics. 2014;13:2321-36 pubmed 出版商 |
| Rahtu Korpela L, Karsikas S, Horkko S, Blanco Sequeiros R, Lammentausta E, Mäkelä K, et al. HIF prolyl 4-hydroxylase-2 inhibition improves glucose and lipid metabolism and protects against obesity and metabolic dysfunction. Diabetes. 2014;63:3324-33 pubmed 出版商 |
| Press T, Viale Bouroncle S, Felthaus O, Gosau M, Morsczeck C. EGR1 supports the osteogenic differentiation of dental stem cells. Int Endod J. 2015;48:185-92 pubmed 出版商 |
| Zeng W, Guo Y, Qi W, Chen J, Yang L, Luo Z, et al. 4-Phenylbutyric acid suppresses inflammation through regulation of endoplasmic reticulum stress of endothelial cells stimulated by uremic serum. Life Sci. 2014;103:15-24 pubmed 出版商 |
| Brugger D, Buffler M, Windisch W. Development of an experimental model to assess the bioavailability of zinc in practical piglet diets. Arch Anim Nutr. 2014;68:73-92 pubmed 出版商 |
| Wong T, Doyle A, Lee J, Jelinek D. Eosinophils regulate peripheral B cell numbers in both mice and humans. J Immunol. 2014;192:3548-58 pubmed 出版商 |
| Cai B, Xie S, Liu F, Simone L, Caplan S, Qin X, et al. Rapid degradation of the complement regulator, CD59, by a novel inhibitor. J Biol Chem. 2014;289:12109-25 pubmed 出版商 |
| Liu Y, Shim E, Nguyen P, Gibbons A, Mitchell J, Poirier M. Tempol protects cardiomyocytes from nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity. Toxicol Sci. 2014;139:133-41 pubmed 出版商 |
| Hung T, Ho C, Liu Y, Lee J, Liao Y, Wu Y, et al. Up-regulation of microRNA-190b plays a role for decreased IGF-1 that induces insulin resistance in human hepatocellular carcinoma. PLoS ONE. 2014;9:e89446 pubmed 出版商 |
| Zheng X, Heaps C, Fisher S. Myosin phosphatase isoforms and related transcripts in the pig coronary circulation and effects of exercise and chronic occlusion. Microvasc Res. 2015;98:166-71 pubmed 出版商 |
| Van Opdenbosch N, Gurung P, Vande Walle L, Fossoul A, Kanneganti T, Lamkanfi M. Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation. Nat Commun. 2014;5:3209 pubmed 出版商 |
| Liang J, Wei J, Lee Y, Hsu S, Lin J, Lin Y. Surfactant-modified nanoclay exhibits an antiviral activity with high potency and broad spectrum. J Virol. 2014;88:4218-28 pubmed 出版商 |
| Yu C, Yu C. Photodynamic therapy with 5-aminolevulinic acid (ALA) impairs tumor initiating and chemo-resistance property in head and neck cancer-derived cancer stem cells. PLoS ONE. 2014;9:e87129 pubmed 出版商 |
| D souza A, Asadi A, Johnson J, Covey S, Kieffer T. Leptin deficiency in rats results in hyperinsulinemia and impaired glucose homeostasis. Endocrinology. 2014;155:1268-79 pubmed 出版商 |
| Kaczmarek M, Holland R, Lavanier S, Troxler J, Fesenkova V, Hanson C, et al. Mechanism of action for the cytotoxic effects of the nitric oxide prodrug JS-K in murine erythroleukemia cells. Leuk Res. 2014;38:377-82 pubmed 出版商 |
| Li K, Yu Y, Zhou C, Kim D, Lin B, Sharp K, et al. Calcium channel ?2?1 proteins mediate trigeminal neuropathic pain states associated with aberrant excitatory synaptogenesis. J Biol Chem. 2014;289:7025-37 pubmed 出版商 |
| Lin H, Lin C, Hsiao P, Wang H, Jiang S, Hsu J, et al. Difference in protein expression profile and chemotherapy drugs response of different progression stages of LNCaP sublines and other human prostate cancer cells. PLoS ONE. 2013;8:e82625 pubmed 出版商 |
| Zhu M, Guo M, Fei L, Pan X, Liu Q. 4-phenylbutyric acid attenuates endoplasmic reticulum stress-mediated pancreatic β-cell apoptosis in rats with streptozotocin-induced diabetes. Endocrine. 2014;47:129-37 pubmed 出版商 |
| Mounce B, Mboko W, Kanack A, Tarakanova V. Primary macrophages rely on histone deacetylase 1 and 2 expression to induce type I interferon in response to gammaherpesvirus infection. J Virol. 2014;88:2268-78 pubmed 出版商 |
| Viale Bouroncle S, Gosau M, Morsczeck C. NOTCH1 signaling regulates the BMP2/DLX-3 directed osteogenic differentiation of dental follicle cells. Biochem Biophys Res Commun. 2014;443:500-4 pubmed 出版商 |
| Schusser B, Yi H, COLLARINI E, Izquierdo S, Harriman W, Etches R, et al. Harnessing gene conversion in chicken B cells to create a human antibody sequence repertoire. PLoS ONE. 2013;8:e80108 pubmed 出版商 |
| Govaert K, Emmink B, Nijkamp M, Cheung Z, Steller E, Fatrai S, et al. Hypoxia after liver surgery imposes an aggressive cancer stem cell phenotype on residual tumor cells. Ann Surg. 2014;259:750-9 pubmed 出版商 |
| Allache R, Lachance S, Guyot M, De Marco P, Merello E, Justice M, et al. Novel mutations in Lrp6 orthologs in mouse and human neural tube defects affect a highly dosage-sensitive Wnt non-canonical planar cell polarity pathway. Hum Mol Genet. 2014;23:1687-99 pubmed 出版商 |
| Zhou C, Luo Z. Electrophysiological characterization of spinal neuron sensitization by elevated calcium channel alpha-2-delta-1 subunit protein. Eur J Pain. 2014;18:649-58 pubmed 出版商 |
| Thies H, Nolte I, Wenk H, Mertens F, Bullerdiek J, Markowski D. Permanent activation of HMGA2 in lipomas mimics its temporal physiological activation linked to the gain of adipose tissue. Obesity (Silver Spring). 2014;22:141-50 pubmed 出版商 |
| Xu J, Li Y, Chen W, Xu Y, Yin L, Ge X, et al. Hepatic carboxylesterase 1 is essential for both normal and farnesoid X receptor-controlled lipid homeostasis. Hepatology. 2014;59:1761-1771 pubmed 出版商 |
| Gini B, Zanca C, Guo D, Matsutani T, Masui K, Ikegami S, et al. The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas. Clin Cancer Res. 2013;19:5722-32 pubmed 出版商 |
| Li K, Kim D, Zaucke F, Luo Z. Trigeminal nerve injury-induced thrombospondin-4 up-regulation contributes to orofacial neuropathic pain states in a rat model. Eur J Pain. 2014;18:489-95 pubmed 出版商 |
| Snoeren N, Emmink B, Koerkamp M, van Hooff S, Goos J, van Houdt W, et al. Maspin is a marker for early recurrence in primary stage III and IV colorectal cancer. Br J Cancer. 2013;109:1636-47 pubmed 出版商 |
| Feldman A, Vasmatzis G, Asmann Y, Davila J, Middha S, Eckloff B, et al. Novel TRAF1-ALK fusion identified by deep RNA sequencing of anaplastic large cell lymphoma. Genes Chromosomes Cancer. 2013;52:1097-102 pubmed 出版商 |
| Chan C, Lee K, Huang Y, Chou C, Lin H, Lee F. Regulation by resveratrol of the cellular factors mediating liver damage and regeneration after acute toxic liver injury. J Gastroenterol Hepatol. 2014;29:603-13 pubmed 出版商 |
| Khan Z, Yaiw K, Wilhelmi V, Lam H, Rahbar A, Stragliotto G, et al. Human cytomegalovirus immediate early proteins promote degradation of connexin 43 and disrupt gap junction communication: implications for a role in gliomagenesis. Carcinogenesis. 2014;35:145-54 pubmed 出版商 |
| Liu L, Martin R, Kohler G, Chan C. Palmitate induces transcriptional regulation of BACE1 and presenilin by STAT3 in neurons mediated by astrocytes. Exp Neurol. 2013;248:482-90 pubmed 出版商 |
| Chang K, Wang C, Kao H, Liang Y, Liu S, Huang L, et al. Overexpression of caldesmon is associated with lymph node metastasis and poorer prognosis in patients with oral cavity squamous cell carcinoma. Cancer. 2013;119:4003-11 pubmed 出版商 |
| Hsu P, Chen H, Yeh Y, Yen C, Wu Y, Hsu C, et al. TPX2 expression is associated with cell proliferation and patient outcome in esophageal squamous cell carcinoma. J Gastroenterol. 2014;49:1231-40 pubmed 出版商 |
| Lee C, Lai Y, Chang H, Liao J, Shyu W, Li C, et al. Inhibition of high-mobility group box 1 in lung reduced airway inflammation and remodeling in a mouse model of chronic asthma. Biochem Pharmacol. 2013;86:940-9 pubmed 出版商 |
| Yeh C, Chiang K, Juang H, S Pang J, Yu C, Lin K, et al. Reappraisal of the therapeutic role of celecoxib in cholangiocarcinoma. PLoS ONE. 2013;8:e69928 pubmed 出版商 |
| Hsieh Y, Chou M, Chen H, Tseng J. IMP1 promotes choriocarcinoma cell migration and invasion through the novel effectors RSK2 and PPME1. Gynecol Oncol. 2013;131:182-90 pubmed 出版商 |
| Morel E, Chamoun Z, Lasiecka Z, Chan R, Williamson R, Vetanovetz C, et al. Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system. Nat Commun. 2013;4:2250 pubmed 出版商 |
| Tigrine C, Bulzomi P, Leone S, Bouriche H, Kameli A, Marino M. Cleome arabica leaf extract has anticancer properties in human cancer cells. Pharm Biol. 2013;51:1508-14 pubmed 出版商 |
| Wen J, Lopes F, Soares G, Farrell S, Nelson C, Qiao Y, et al. Phenotypic and functional consequences of haploinsufficiency of genes from exocyst and retinoic acid pathway due to a recurrent microdeletion of 2p13.2. Orphanet J Rare Dis. 2013;8:100 pubmed 出版商 |
| Emmink B, Verheem A, van Houdt W, Steller E, Govaert K, Pham T, et al. The secretome of colon cancer stem cells contains drug-metabolizing enzymes. J Proteomics. 2013;91:84-96 pubmed 出版商 |
| Rathmanner N, Haigl B, Vanas V, Doriguzzi A, Gsur A, Sutterlüty Fall H. Sprouty2 but not Sprouty4 is a potent inhibitor of cell proliferation and migration of osteosarcoma cells. FEBS Lett. 2013;587:2597-605 pubmed 出版商 |
| Kremer K, Peterson K, Schneider P, Meng X, Dai H, Hess A, et al. CXCR4 chemokine receptor signaling induces apoptosis in acute myeloid leukemia cells via regulation of the Bcl-2 family members Bcl-XL, Noxa, and Bak. J Biol Chem. 2013;288:22899-914 pubmed 出版商 |
| Ko C, Cheng C, Lai C, Tzu T, Chiu C, Lin M, et al. Differential proteomic analysis of cancer stem cell properties in hepatocellular carcinomas by isobaric tag labeling and mass spectrometry. J Proteome Res. 2013;12:3573-85 pubmed 出版商 |
| Shie M, Ding S. Integrin binding and MAPK signal pathways in primary cell responses to surface chemistry of calcium silicate cements. Biomaterials. 2013;34:6589-606 pubmed 出版商 |
| Liu T, Zhang S, Xiang D, Wang Y. Induction of hepatocyte-like cells from mouse embryonic stem cells by lentivirus-mediated constitutive expression of Foxa2/Hnf4a. J Cell Biochem. 2013;114:2531-41 pubmed 出版商 |
| Babic I, Anderson E, Tanaka K, Guo D, Masui K, Li B, et al. EGFR mutation-induced alternative splicing of Max contributes to growth of glycolytic tumors in brain cancer. Cell Metab. 2013;17:1000-8 pubmed 出版商 |
| Formosa R, Xuereb Anastasi A, Vassallo J. Aip regulates cAMP signalling and GH secretion in GH3 cells. Endocr Relat Cancer. 2013;20:495-505 pubmed 出版商 |
| Das I, Png C, Oancea I, Hasnain S, Lourie R, Proctor M, et al. Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins. J Exp Med. 2013;210:1201-16 pubmed 出版商 |
| Zeng J, Kim D, Li K, Sharp K, Steward O, Zaucke F, et al. Thrombospondin-4 contributes to spinal cord injury-induced changes in nociception. Eur J Pain. 2013;17:1458-64 pubmed 出版商 |
| Yoon H, Radulovic M, Wu J, Blaber S, Blaber M, Fehlings M, et al. Kallikrein 6 signals through PAR1 and PAR2 to promote neuron injury and exacerbate glutamate neurotoxicity. J Neurochem. 2013;127:283-98 pubmed 出版商 |
| Rafalski V, Ho P, Brett J, Ucar D, Dugas J, Pollina E, et al. Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain. Nat Cell Biol. 2013;15:614-24 pubmed 出版商 |
| Cai H, Peng F. Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells. Oncol Rep. 2013;30:269-75 pubmed 出版商 |
| Kral R, Mayer C, Vanas V, Gsur A, Sutterlüty Fall H. In non-small cell lung cancer mitogenic signaling leaves Sprouty1 protein levels unaffected. Cell Biochem Funct. 2014;32:96-100 pubmed 出版商 |
| Huang T, Chong K, Ojcius D, Wu Y, Ko Y, Wu C, et al. Hirsutella sinensis mycelium suppresses interleukin-1? and interleukin-18 secretion by inhibiting both canonical and non-canonical inflammasomes. Sci Rep. 2013;3:1374 pubmed 出版商 |
| Park Y, Carr T. Unsaturated fatty acids and phytosterols regulate cholesterol transporter genes in Caco-2 and HepG2 cell lines. Nutr Res. 2013;33:154-61 pubmed 出版商 |
| Allen J, Bell G, Kuzirian A, Hanlon R. Cuttlefish skin papilla morphology suggests a muscular hydrostatic function for rapid changeability. J Morphol. 2013;274:645-56 pubmed 出版商 |
| Drucker K, Paulsen A, Giannini C, Decker P, Blaber S, Blaber M, et al. Clinical significance and novel mechanism of action of kallikrein 6 in glioblastoma. Neuro Oncol. 2013;15:305-18 pubmed 出版商 |
| Salih D, Rashid A, Colas D, de la Torre Ubieta L, Zhu R, Morgan A, et al. FoxO6 regulates memory consolidation and synaptic function. Genes Dev. 2012;26:2780-801 pubmed 出版商 |
| Berryer M, Hamdan F, Klitten L, Møller R, Carmant L, Schwartzentruber J, et al. Mutations in SYNGAP1 cause intellectual disability, autism, and a specific form of epilepsy by inducing haploinsufficiency. Hum Mutat. 2013;34:385-94 pubmed 出版商 |
| Xie W, Parker J, Heaps C. Exercise training-enhanced, endothelium-dependent dilation mediated by altered regulation of BK(Ca) channels in collateral-dependent porcine coronary arterioles. Microcirculation. 2013;20:170-82 pubmed 出版商 |
| Lin C, Jan M, Kuo J, Hsu L, Lin Y. Protective role of autophagy in branched polyethylenimine (25K)- and poly(L-lysine) (30-70K)-induced cell death. Eur J Pharm Sci. 2012;47:865-74 pubmed 出版商 |
| Hånell A, Clausen F, Djupsjö A, Vallstedt A, Patra K, Israelsson C, et al. Functional and histological outcome after focal traumatic brain injury is not improved in conditional EphA4 knockout mice. J Neurotrauma. 2012;29:2660-71 pubmed 出版商 |
| Lee W, Kan D, Chen Y, Han S, Lu K, Chien C. Suppression of extensive neurofilament phosphorylation rescues ?-Internexin/peripherin-overexpressing PC12 cells from neuronal cell death. PLoS ONE. 2012;7:e43883 pubmed 出版商 |
| Aro E, Khatri R, Gerard O Riley R, Mangiavini L, Myllyharju J, Schipani E. Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes. J Biol Chem. 2012;287:37134-44 pubmed 出版商 |
| Maj M, Milenkovic I, Bauer J, Berggard T, Veit M, Ilhan Mutlu A, et al. Novel insights into the distribution and functional aspects of the calcium binding protein secretagogin from studies on rat brain and primary neuronal cell culture. Front Mol Neurosci. 2012;5:84 pubmed 出版商 |
| Minutolo A, Grelli S, Marino Merlo F, Cordero F, Brandi A, Macchi B, et al. D(-)lentiginosine-induced apoptosis involves the intrinsic pathway and is p53-independent. Cell Death Dis. 2012;3:e358 pubmed 出版商 |
| CALNAN D, Webb A, White J, Stowe T, Goswami T, Shi X, et al. Methylation by Set9 modulates FoxO3 stability and transcriptional activity. Aging (Albany NY). 2012;4:462-79 pubmed |
| Wu H, Lu Y, Shen C, Patel N, Gan L, Xiong W, et al. Distinct roles of muscle and motoneuron LRP4 in neuromuscular junction formation. Neuron. 2012;75:94-107 pubmed 出版商 |
| Wu M, Hou M, Lin Y, Kuo C. 2,4,5-TMBA, a natural inhibitor of cyclooxygenase-2, suppresses adipogenesis and promotes lipolysis in 3T3-L1 adipocytes. J Agric Food Chem. 2012;60:7262-9 pubmed 出版商 |
| Li T, Liu G, Li J, Wang X, Liu Q, Liu Z, et al. Mechanisms of prostate permeability triggered by microbubble-mediated acoustic cavitation. Cell Biochem Biophys. 2012;64:147-53 pubmed 出版商 |
| Wehenkel M, Ban J, Ho Y, Carmony K, Hong J, Kim K. A selective inhibitor of the immunoproteasome subunit LMP2 induces apoptosis in PC-3 cells and suppresses tumour growth in nude mice. Br J Cancer. 2012;107:53-62 pubmed 出版商 |
| Dawson P, Rakoczy J, Simmons D. Placental, renal, and ileal sulfate transporter gene expression in mouse gestation. Biol Reprod. 2012;87:43 pubmed 出版商 |
| Wu H, Lu Y, Barik A, Joseph A, Taketo M, Xiong W, et al. ?-Catenin gain of function in muscles impairs neuromuscular junction formation. Development. 2012;139:2392-404 pubmed 出版商 |
| Herroon M, Rajagurubandara E, Rudy D, Chalasani A, Hardaway A, Podgorski I. Macrophage cathepsin K promotes prostate tumor progression in bone. Oncogene. 2013;32:1580-93 pubmed 出版商 |
| Pohjanvirta R, Miettinen H, Sankari S, Hegde N, Lindén J. Unexpected gender difference in sensitivity to the acute toxicity of dioxin in mice. Toxicol Appl Pharmacol. 2012;262:167-76 pubmed 出版商 |
| Yu M, Ge C, Zeng W, Mi Y, Zhang C. Retinoic acid promotes proliferation of chicken primordial germ cells via activation of PI3K/Akt-mediated NF-?B signalling cascade. Cell Biol Int. 2012;36:705-12 pubmed 出版商 |
| Chang W, Hu F, Yu C, Wang H, Feng H, Lan C, et al. Quercetin in elimination of tumor initiating stem-like and mesenchymal transformation property in head and neck cancer. Head Neck. 2013;35:413-9 pubmed 出版商 |
| Hsieh Y, Chou L, Chang P, Yang C, Kao M, Hong C. Low-level laser therapy alleviates neuropathic pain and promotes function recovery in rats with chronic constriction injury: possible involvements in hypoxia-inducible factor 1? (HIF-1?). J Comp Neurol. 2012;520:2903-16 pubmed 出版商 |
| Carmony K, Kim K. PROTAC-induced proteolytic targeting. Methods Mol Biol. 2012;832:627-38 pubmed 出版商 |
| Govaert K, Nijkamp M, Emmink B, Steller E, Minchinton A, Kranenburg O, et al. Effects of tirapazamine on experimental colorectal liver metastases after radiofrequency ablation. Br J Surg. 2012;99:567-75 pubmed 出版商 |
| Zhang B, Liang C, Bates R, Yin Y, Xiong W, Mei L. Wnt proteins regulate acetylcholine receptor clustering in muscle cells. Mol Brain. 2012;5:7 pubmed 出版商 |
| Zhou Q, Xu G, Zhang X, Cao C, Zhou Z. Proteomics of post-traumatic proliferative vitreoretinopathy in rabbit retina reveals alterations to a variety of functional proteins. Curr Eye Res. 2012;37:318-26 pubmed 出版商 |
| Swain U, Rao K. Age-dependent decline of DNA base excision repair activity in rat cortical neurons. Mech Ageing Dev. 2012;133:186-94 pubmed 出版商 |
| Lee W, Chen Y, Kan D, Chien C. A neuronal death model: overexpression of neuronal intermediate filament protein peripherin in PC12 cells. J Biomed Sci. 2012;19:8 pubmed 出版商 |
| Edgel K, McMillen T, Wei H, Pamir N, Houston B, Caldwell M, et al. Obesity and weight loss result in increased adipose tissue ABCG1 expression in db/db mice. Biochim Biophys Acta. 2012;1821:425-34 pubmed 出版商 |
| Szabat M, Kalynyak T, Lim G, Chu K, Yang Y, Asadi A, et al. Musashi expression in ?-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes. Cell Death Dis. 2011;2:e232 pubmed 出版商 |
| Tsai Y, Huang Y, Chao Y, Hu K, Chin L, Chou S, et al. Identification of the nanogold particle-induced endoplasmic reticulum stress by omic techniques and systems biology analysis. ACS Nano. 2011;5:9354-69 pubmed 出版商 |
| Yang L, Yang Z, Guo R, Ye J, Liu H. Angiotensin II induces extracellular matrix metalloproteinase inducer expression via an AT1R dependent pathway in aortic atherosclerotic plaque in apolipoprotein E knockout mice. J Renin Angiotensin Aldosterone Syst. 2012;13:67-75 pubmed 出版商 |
| Khan Z, Akhtar M, Ekström T. HDAC inhibitor 4-phenylbutyrate preserves immature phenotype of human embryonic midbrain stem cells: implications for the involvement of DNA methyltransferase. Int J Mol Med. 2011;28:977-83 pubmed 出版商 |
| Chiang K, Yeh C, Chen H, Lee J, Juang H, Chen M, et al. 19-Nor-2?-(3-hydroxypropyl)-1?,25-dihydroxyvitamin D3 (MART-10) is a potent cell growth regulator with enhanced chemotherapeutic potency in liver cancer cells. Steroids. 2011;76:1513-9 pubmed 出版商 |
| Gao L, Coope H, Grant S, Ma A, Ley S, Harhaj E. ABIN1 protein cooperates with TAX1BP1 and A20 proteins to inhibit antiviral signaling. J Biol Chem. 2011;286:36592-602 pubmed 出版商 |
| Patschan O, Shariat S, Chade D, Karakiewicz P, Ashfaq R, Lotan Y, et al. Association of tumor-associated trypsin inhibitor (TATI) expression with molecular markers, pathologic features and clinical outcomes of urothelial carcinoma of the urinary bladder. World J Urol. 2012;30:785-94 pubmed 出版商 |
| Corcoran M, Lichtenstein A, Meydani M, Dillard A, Schaefer E, Lamon Fava S. The effect of 17{beta}-estradiol on cholesterol content in human macrophages is influenced by the lipoprotein milieu. J Mol Endocrinol. 2011;47:109-17 pubmed |
| Ge X, Yin L, Ma H, Li T, Chiang J, Zhang Y. Aldo-keto reductase 1B7 is a target gene of FXR and regulates lipid and glucose homeostasis. J Lipid Res. 2011;52:1561-8 pubmed 出版商 |
| Vitari A, Leong K, Newton K, Yee C, O Rourke K, Liu J, et al. COP1 is a tumour suppressor that causes degradation of ETS transcription factors. Nature. 2011;474:403-6 pubmed 出版商 |
| Winter N, Nimzyk R, Bösche C, Meyer A, Bullerdiek J. Chromatin immunoprecipitation to analyze DNA binding sites of HMGA2. PLoS ONE. 2011;6:e18837 pubmed 出版商 |
| Nijkamp M, Hoogwater F, Govaert K, Steller E, Verheem A, Kranenburg O, et al. A role for CD95 signaling in ischemia/reperfusion-induced invasion and outgrowth of colorectal micrometastases in mouse liver. J Surg Oncol. 2011;104:198-204 pubmed 出版商 |
| Huang A, Kao Y, Toh S, Lin P, Chou C, Hu H, et al. UBE2M-mediated p27(Kip1) degradation in gemcitabine cytotoxicity. Biochem Pharmacol. 2011;82:35-42 pubmed 出版商 |
| Raats D, de Bruijn M, Steller E, Emmink B, Borel Rinkes I, Kranenburg O. Synergistic killing of colorectal cancer cells by oxaliplatin and ABT-737. Cell Oncol (Dordr). 2011;34:307-13 pubmed 出版商 |
| Scarisbrick I, Epstein B, Cloud B, Yoon H, Wu J, Renner D, et al. Functional role of kallikrein 6 in regulating immune cell survival. PLoS ONE. 2011;6:e18376 pubmed 出版商 |
| Kim S, Nian C, McIntosh C. Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARγ and histone acetylation. J Lipid Res. 2011;52:759-70 pubmed 出版商 |
| Hildebrand J, Luo Z, Manske M, Price Troska T, Ziesmer S, Lin W, et al. A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling. J Exp Med. 2010;207:2569-79 pubmed 出版商 |
| Chen C, Chyau C, Liao C, Hu T, Kuo C. Enhanced anti-inflammatory activities of Monascus pilosus fermented products by addition of ginger to the medium. J Agric Food Chem. 2010;58:12006-13 pubmed 出版商 |
| Moiseyev G, Nikolaeva O, Chen Y, Farjo K, Takahashi Y, Ma J. Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease. Proc Natl Acad Sci U S A. 2010;107:17551-6 pubmed 出版商 |
| Chavez C, Keravala A, Woodard L, Hillman R, Stowe T, Chu J, et al. Kinetics and longevity of ΦC31 integrase in mouse liver and cultured cells. Hum Gene Ther. 2010;21:1287-97 pubmed 出版商 |
| van Houdt W, de Bruijn M, Emmink B, Raats D, Hoogwater F, Borel Rinkes I, et al. Oncogenic K-ras activates p38 to maintain colorectal cancer cell proliferation during MEK inhibition. Cell Oncol. 2010;32:245-57 pubmed 出版商 |
| de Bruijn M, Raats D, Hoogwater F, van Houdt W, Cameron K, Medema J, et al. Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa. Br J Cancer. 2010;102:1254-64 pubmed 出版商 |
| Lan C, Sheng J, Fang D, Meng Q, Fan L, Huang Z. Involvement of VDAC1 and Bcl-2 family of proteins in VacA-induced cytochrome c release and apoptosis of gastric epithelial carcinoma cells. J Dig Dis. 2010;11:43-9 pubmed 出版商 |
| Matluk N, Rochira J, Karaczyn A, Adams T, Verdi J. A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. BMC Biol. 2010;8:7 pubmed 出版商 |
| Maj M, Gartner W, Ilhan A, Neziri D, Attems J, Wagner L. Expression of TAU in insulin-secreting cells and its interaction with the calcium-binding protein secretagogin. J Endocrinol. 2010;205:25-36 pubmed 出版商 |
| Macchi B, Minutolo A, Grelli S, Cardona F, Cordero F, Mastino A, et al. The novel proapoptotic activity of nonnatural enantiomer of Lentiginosine. Glycobiology. 2010;20:500-6 pubmed 出版商 |
| Woodard L, Hillman R, Keravala A, Lee S, Calos M. Effect of nuclear localization and hydrodynamic delivery-induced cell division on phiC31 integrase activity. Gene Ther. 2010;17:217-26 pubmed 出版商 |
| Zhang B, Luo S, Wang Q, Suzuki T, Xiong W, Mei L. LRP4 serves as a coreceptor of agrin. Neuron. 2008;60:285-97 pubmed 出版商 |
| Luo S, Zhang B, Dong X, Tao Y, Ting A, Zhou Z, et al. HSP90 beta regulates rapsyn turnover and subsequent AChR cluster formation and maintenance. Neuron. 2008;60:97-110 pubmed 出版商 |
| Fogarty J, Delp M, Muller Delp J, Laine G, Parker J, Heaps C. Neuropilin-1 is essential for enhanced VEGF(165)-mediated vasodilatation in collateral-dependent coronary arterioles of exercise-trained pigs. J Vasc Res. 2009;46:152-61 pubmed 出版商 |
| Barthel S, Gavino J, Wiese G, Jaynes J, Siddiqui J, Dimitroff C. Analysis of glycosyltransferase expression in metastatic prostate cancer cells capable of rolling activity on microvascular endothelial (E)-selectin. Glycobiology. 2008;18:806-17 pubmed 出版商 |
| Elsawa S, Novak A, Grote D, Konopleva M, Andreeff M, Witzig T, et al. CDDO-imidazolide mediated inhibition of malignant cell growth in Waldenström macroglobulinemia. Leuk Res. 2008;32:1895-902 pubmed 出版商 |
| Heazlewood C, Cook M, Eri R, Price G, Tauro S, Taupin D, et al. Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis. PLoS Med. 2008;5:e54 pubmed 出版商 |
| Dror V, Kalynyak T, Bychkivska Y, Frey M, Tee M, Jeffrey K, et al. Glucose and endoplasmic reticulum calcium channels regulate HIF-1beta via presenilin in pancreatic beta-cells. J Biol Chem. 2008;283:9909-16 pubmed 出版商 |
| Alejandro E, Johnson J. Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis. J Biol Chem. 2008;283:2407-17 pubmed |
| Greer E, Oskoui P, Banko M, Maniar J, Gygi M, Gygi S, et al. The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor. J Biol Chem. 2007;282:30107-19 pubmed |
| Zhang S, Suvannasankha A, Crean C, White V, Johnson A, Chen C, et al. OSU-03012, a novel celecoxib derivative, is cytotoxic to myeloma cells and acts through multiple mechanisms. Clin Cancer Res. 2007;13:4750-8 pubmed |
| Ougolkov A, Bone N, Fernandez Zapico M, Kay N, Billadeau D. Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells. Blood. 2007;110:735-42 pubmed |
| Park K, Hallows J, Chakrabarty P, Davies P, Vincent I. Conditional neuronal simian virus 40 T antigen expression induces Alzheimer-like tau and amyloid pathology in mice. J Neurosci. 2007;27:2969-78 pubmed |
| Dennis V, Jefferson A, Singh S, Ganapamo F, Philipp M. Interleukin-10 anti-inflammatory response to Borrelia burgdorferi, the agent of Lyme disease: a possible role for suppressors of cytokine signaling 1 and 3. Infect Immun. 2006;74:5780-9 pubmed |
| Abramovich D, Parborell F, Tesone M. Effect of a vascular endothelial growth factor (VEGF) inhibitory treatment on the folliculogenesis and ovarian apoptosis in gonadotropin-treated prepubertal rats. Biol Reprod. 2006;75:434-41 pubmed |
| Rice P, Peters S, Beard K, Ahnen D. Sulindac independently modulates extracellular signal-regulated kinase 1/2 and cyclic GMP-dependent protein kinase signaling pathways. Mol Cancer Ther. 2006;5:746-54 pubmed |
| Csiszar A, Ahmad M, Smith K, Labinskyy N, Gao Q, Kaley G, et al. Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype. Am J Pathol. 2006;168:629-38 pubmed |
| Moiseyev G, Chen Y, Takahashi Y, Wu B, Ma J. RPE65 is the isomerohydrolase in the retinoid visual cycle. Proc Natl Acad Sci U S A. 2005;102:12413-8 pubmed |
| Barnidge D, Jelinek D, Muddiman D, Kay N. Quantitative protein expression analysis of CLL B cells from mutated and unmutated IgV(H) subgroups using acid-cleavable isotope-coded affinity tag reagents. J Proteome Res. 2005;4:1310-7 pubmed |
| Nagasawa H, Peng Y, Wilson P, Lio Y, Chen D, Bedford J, et al. Role of homologous recombination in the alpha-particle-induced bystander effect for sister chromatid exchanges and chromosomal aberrations. Radiat Res. 2005;164:141-7 pubmed |
| Liu X, Manser T. Antinuclear antigen B cells that down-regulate surface B cell receptor during development to mature, follicular phenotype do not display features of anergy in vitro. J Immunol. 2005;174:4505-15 pubmed |
| Peng Y, Woods R, Beamish H, Ye R, Lees Miller S, Lavin M, et al. Deficiency in the catalytic subunit of DNA-dependent protein kinase causes down-regulation of ATM. Cancer Res. 2005;65:1670-7 pubmed |
| Sung S, Yang H, Uryu K, Lee E, Zhao L, Shineman D, et al. Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease. Am J Pathol. 2004;165:2197-206 pubmed |
| Adler S, Huang H. Oxidant stress in kidneys of spontaneously hypertensive rats involves both oxidase overexpression and loss of extracellular superoxide dismutase. Am J Physiol Renal Physiol. 2004;287:F907-13 pubmed |
| Chong V, Costain W, Marriott J, Sindwani S, Knauer D, Wang J, et al. Differential display polymerase chain reaction reveals increased expression of striatal rat glia-derived nexin following chronic clozapine treatment. Pharmacogenomics J. 2004;4:379-87 pubmed |
| Mukherjee P, Abate L, Seyfried T. Antiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors. Clin Cancer Res. 2004;10:5622-9 pubmed |
| Laughlin R, McGugan G, Powell R, Welter B, Temesvari L. Involvement of raft-like plasma membrane domains of Entamoeba histolytica in pinocytosis and adhesion. Infect Immun. 2004;72:5349-57 pubmed |
| Watters J, Kraja A, Meucci M, Province M, McLeod H. Genome-wide discovery of loci influencing chemotherapy cytotoxicity. Proc Natl Acad Sci U S A. 2004;101:11809-14 pubmed |
| Dietz A, Souan L, Knutson G, Bulur P, Litzow M, Vuk Pavlovic S. Imatinib mesylate inhibits T-cell proliferation in vitro and delayed-type hypersensitivity in vivo. Blood. 2004;104:1094-9 pubmed |
| Hawkins B, Fischer L. Inhibition of insulin synthesis by cyproheptadine: effects on translation. Toxicol Sci. 2004;79:258-65 pubmed |
| Thornton M, Kudo D, Rayman P, Horton C, Molto L, Cathcart M, et al. Degradation of NF-kappa B in T cells by gangliosides expressed on renal cell carcinomas. J Immunol. 2004;172:3480-90 pubmed |
| Sun D, Huang A, Yan E, Wu Z, Yan C, Kaminski P, et al. Reduced release of nitric oxide to shear stress in mesenteric arteries of aged rats. Am J Physiol Heart Circ Physiol. 2004;286:H2249-56 pubmed |
| Adler S, Huang H, Wolin M, Kaminski P. Oxidant stress leads to impaired regulation of renal cortical oxygen consumption by nitric oxide in the aging kidney. J Am Soc Nephrol. 2004;15:52-60 pubmed |
| Liao J, Xu X, Wargovich M. Direct reprobing with anti-beta-actin antibody as an internal control for western blotting analysis. Biotechniques. 2000;28:216-8 pubmed |
