产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
IRE1 alpha [p Ser724] Antibody - BSA Free
目录 :
NB100-2323
规格 :
0.1 ml (also 0.025 ml)
价格 :
449美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
DyLight系列染料650
克隆名称 :
OTI2B3
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 205
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 5e
Lei X, Lin H, Wang J, Ou Z, Ruan Y, Sadagopan A, et al. Mitochondrial fission induces immunoescape in solid tumors through decreasing MHC-I surface expression. Nat Commun. 2022;13:3882 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6h
Zhou Y, Ye X, Zhang C, Wang J, Guan Z, Yan J, et al. Ufl1 deficiency causes kidney atrophy associated with disruption of endoplasmic reticulum homeostasis. J Genet Genomics. 2021;48:403-410 pubmed 出版商
  • 免疫印迹; 小鼠; 图 11e
Cao X, Shu Y, Chen Y, Xu Q, Guo G, Wu Z, et al. Mettl14-Mediated m6A Modification Facilitates Liver Regeneration by Maintaining Endoplasmic Reticulum Homeostasis. Cell Mol Gastroenterol Hepatol. 2021;12:633-651 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1a
Lim Y, Kim S, Kim E. Palmitate reduces starvation-induced ER stress by inhibiting ER-phagy in hypothalamic cells. Mol Brain. 2021;14:65 pubmed 出版商
  • 免疫印迹; 人类; 图 6b
Wanschel A, Guizoni D, Lorza Gil E, Salerno A, Paiva A, Dorighello G, et al. The Presence of Cholesteryl Ester Transfer Protein (CETP) in Endothelial Cells Generates Vascular Oxidative Stress and Endothelial Dysfunction. Biomolecules. 2021;11: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5a
Lanzillotta C, Greco V, Valentini D, Villani A, Folgiero V, Caforio M, et al. Proteomics Study of Peripheral Blood Mononuclear Cells in Down Syndrome Children. Antioxidants (Basel). 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 图 2e
  • 免疫印迹; 人类; 图 2h
Schiattarella G, Altamirano F, Tong D, French K, Villalobos E, Kim S, et al. Nitrosative stress drives heart failure with preserved ejection fraction. Nature. 2019;568:351-356 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 s4c
  • 免疫印迹; 小鼠; 1:1000; 图 2b
  • 免疫组化-冰冻切片; 人类; 1:50; 图 6d
Wheeler M, Jaronen M, Covacu R, Zandee S, Scalisi G, Rothhammer V, et al. Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation. Cell. 2019;176:581-596.e18 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Marcassa E, Raimondi M, Anwar T, Eskelinen E, Myers M, Triolo G, et al. Calpain mobilizes Atg9/Bif-1 vesicles from Golgi stacks upon autophagy induction by thapsigargin. Biol Open. 2017;6:551-562 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4a
Liu J, Wang Y, Song L, Zeng L, Yi W, Liu T, et al. A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability. Nat Commun. 2017;8:14186 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4c
Mukhopadhyay C, Triplett A, Bargar T, HECKMAN C, Wagner K, Naramura M. Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation. Proc Natl Acad Sci U S A. 2016;113:E8228-E8237 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3a
Tripathi M, Zhang C, Singh B, Sinha R, Moe K, DeSilva D, et al. Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation. Cell Death Dis. 2016;7:e2513 pubmed 出版商
  • 免疫组化; 人类; 图 4e
  • 免疫印迹; 人类; 图 4a
Sareddy G, Viswanadhapalli S, Surapaneni P, Suzuki T, Brenner A, Vadlamudi R. Novel KDM1A inhibitors induce differentiation and apoptosis of glioma stem cells via unfolded protein response pathway. Oncogene. 2017;36:2423-2434 pubmed 出版商
Wang W, Hawkridge A, Ma Y, Zhang B, Mangrum J, Hassan Z, et al. Ubiquitin-like protein 5 is a novel player in the UPR-PERK arm and ER stress-induced cell death. J Biol Chem. 2023;299:104915 pubmed 出版商
Xiao J, Huang J, Jian X, Wang H, Lan H, Liao Z, et al. IRE1α arm of unfolded protein response in muscle-specific TGF-β signaling-mediated regulation of muscle cell immunological properties. Cell Mol Biol Lett. 2023;28:15 pubmed 出版商
Yu J, Shen S, Yan Y, Liu L, Luo R, Liu S, et al. Iodide Excess Inhibits Thyroid Hormone Synthesis Pathway Involving XBP1-Mediated Regulation. Nutrients. 2023;15: pubmed 出版商
Yu D, Li J, Wang Y, Guo D, Zhang X, Chen M, et al. Oridonin ameliorates acetaminophen-induced acute liver injury through ATF4/PGC-1α pathway. Drug Dev Res. 2023;84:211-225 pubmed 出版商
Rahman M, Umashankar B, Choucair H, Pazderka C, Bourget K, Chen Y, et al. Inclusion of the in-chain sulfur in 3-thiaCTU increases the efficiency of mitochondrial targeting and cell killing by anticancer aryl-urea fatty acids. Eur J Pharmacol. 2023;939:175470 pubmed 出版商
Dudkevich R, Koh J, Beaudoin Chabot C, Celik C, Lebenthal Loinger I, Karako Lampert S, et al. Neuronal IRE-1 coordinates an organism-wide cold stress response by regulating fat metabolism. Cell Rep. 2022;41:111739 pubmed 出版商
Madhamanchi K, Madhamanchi P, Jayalakshmi S, Panigrahi M, Patil A, Phanithi P. Endoplasmic reticulum stress and unfolded protein accumulation correlate to seizure recurrence in focal cortical dysplasia patients. Cell Stress Chaperones. 2022;27:633-643 pubmed 出版商
Pritchard K, Jing X, Teng M, Wells C, Jia S, Afolayan A, et al. Role of endoplasmic reticulum stress in impaired neonatal lung growth and bronchopulmonary dysplasia. PLoS ONE. 2022;17:e0269564 pubmed 出版商
Peng D, Wang Y, Huang T, Luo D, Qiao L, Wang Q, et al. Ligustilide Improves Cognitive Impairment via Regulating the SIRT1/IRE1α/XBP1s/CHOP Pathway in Vascular Dementia Rats. Oxid Med Cell Longev. 2022;2022:6664990 pubmed 出版商
Jian Z, Han Y, Zhang W, Li C, Guo W, Feng X, et al. Anti-tumor effects of dual PI3K-HDAC inhibitor CUDC-907 on activation of ROS-IRE1α-JNK-mediated cytotoxic autophagy in esophageal cancer. Cell Biosci. 2022;12:135 pubmed 出版商
SOTO I, Couvillion M, Hansen K, McShane E, Moran J, Barrientos A, et al. Balanced mitochondrial and cytosolic translatomes underlie the biogenesis of human respiratory complexes. Genome Biol. 2022;23:170 pubmed 出版商
Chen Y, Zhang T, Zeng S, Xu R, Jin K, Coorey N, et al. Transketolase in human Müller cells is critical to resist light stress through the pentose phosphate and NRF2 pathways. Redox Biol. 2022;54:102379 pubmed 出版商
Chen J, Wu C, Jheng J, Chao C, Huang J, Hung K, et al. The down-regulation of XBP1, an unfolded protein response effector, promotes acute kidney injury to chronic kidney disease transition. J Biomed Sci. 2022;29:46 pubmed 出版商
Chakraborty S, Basu A. miR-451a Regulates Neuronal Apoptosis by Modulating 14-3-3ζ-JNK Axis upon Flaviviral Infection. mSphere. 2022;7:e0020822 pubmed 出版商
Fanning S, Cirka H, Thies J, Jeong J, Niemi S, Yoon J, et al. Lipase regulation of cellular fatty acid homeostasis as a Parkinson's disease therapeutic strategy. NPJ Parkinsons Dis. 2022;8:74 pubmed 出版商
Wang X, Xin H, Xing M, Gu X, Hao Y. Acute Endoplasmic Reticulum Stress Induces Inflammation Reaction, Complement System Activation, and Lipid Metabolism Disorder of Piglet Livers: A Proteomic Approach. Front Physiol. 2022;13:857853 pubmed 出版商
Li Q, Fan X, Lu W, Sun C, Pei Z, Zhang M, et al. Novel NPR2 Gene Mutations Affect Chondrocytes Function via ER Stress in Short Stature. Cells. 2022;11: pubmed 出版商
Visa A, Alza L, Cant xed C, Herreros J. Tetralol derivative NNC-55-0396 induces glioblastoma cell death by activating IRE1α, JNK1 and calcium signaling. Biomed Pharmacother. 2022;149:112881 pubmed 出版商
Lu H, Gomaa A, Wang Bishop L, Ballout F, Hu T, McDonald O, et al. Unfolded Protein Response Is Activated by Aurora Kinase A in Esophageal Adenocarcinoma. Cancers (Basel). 2022;14: pubmed 出版商
Srinivasan M, Bhopale K, Caracheo A, Kaphalia L, Gong B, Popov V, et al. Exposure to binge ethanol and fatty acid ethyl esters exacerbates chronic ethanol-induced pancreatic injury in hepatic alcohol dehydrogenase-deficient deer mice. Am J Physiol Gastrointest Liver Physiol. 2022;322:G327-G345 pubmed 出版商
Abdullah C, Aishwarya R, Alam S, Remex N, Morshed M, Nitu S, et al. The molecular role of Sigmar1 in regulating mitochondrial function through mitochondrial localization in cardiomyocytes. Mitochondrion. 2022;62:159-175 pubmed 出版商
Tanaka K, Kandori S, Sakka S, Nitta S, Tanuma K, Shiga M, et al. ELOVL2 promotes cancer progression by inhibiting cell apoptosis in renal cell carcinoma. Oncol Rep. 2022;47: pubmed 出版商
Xia H, Zhao H, Yang W, Luo X, Wei J, Xia H. MiR-195-5p represses inflammation, apoptosis, oxidative stress, and endoplasmic reticulum stress in sepsis-induced myocardial injury by targeting activating transcription factor 6. Cell Biol Int. 2022;46:243-254 pubmed 出版商
Li S, Zhao F, Tang Q, Xi C, He J, Wang Y, et al. Sarco/endoplasmic reticulum Ca2+ -ATPase (SERCA2b) mediates oxidation-induced endoplasmic reticulum stress to regulate neuropathic pain. Br J Pharmacol. 2021;: pubmed 出版商
Fan Y, Wolford B, Lu H, Liang W, Sun J, Zhou W, et al. Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2. iScience. 2021;24:103196 pubmed 出版商
Chunhacha P, Pinkaew D, Sinthujaroen P, Bowles D, Fujise K. Fortilin inhibits p53, halts cardiomyocyte apoptosis, and protects the heart against heart failure. Cell Death Discov. 2021;7:310 pubmed 出版商
Khoi C, Lin Y, Chen J, Liu B, Lin T, Hung K, et al. Selective Activation of Endoplasmic Reticulum Stress by Reactive-Oxygen-Species-Mediated Ochratoxin A-Induced Apoptosis in Tubular Epithelial Cells. Int J Mol Sci. 2021;22: pubmed 出版商
Mareninova O, Dillon D, Wightman C, Yakubov I, Takahashi T, Gaisano H, et al. Rab9 Mediates Pancreatic Autophagy Switch From Canonical to Noncanonical, Aggravating Experimental Pancreatitis. Cell Mol Gastroenterol Hepatol. 2021;13:599-622 pubmed 出版商
Shaban M, Müller C, Mayr Buro C, Weiser H, Meier Soelch J, Albert B, et al. Multi-level inhibition of coronavirus replication by chemical ER stress. Nat Commun. 2021;12:5536 pubmed 出版商
Zhao P, Huang P, Xu T, Xiang X, Sun Y, Liu J, et al. Fat body Ire1 regulates lipid homeostasis through the Xbp1s-FoxO axis in Drosophila. iScience. 2021;24:102819 pubmed 出版商
EINSTEIN J, Perelis M, Chaim I, Meena J, Nussbacher J, Tankka A, et al. Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer. Mol Cell. 2021;81:3048-3064.e9 pubmed 出版商
Witte F, Ruiz Orera J, Mattioli C, Blachut S, Adami E, Schulz J, et al. A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion. Genome Biol. 2021;22:191 pubmed 出版商
Ricci D, Tutton S, Marrocco I, Ying M, Blumenthal D, Eletto D, et al. An interdomain helix in IRE1α mediates the conformational change required for the sensor's activation. J Biol Chem. 2021;296:100781 pubmed 出版商
Zhemkov V, Ditlev J, Lee W, Wilson M, Liou J, Rosen M, et al. The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains. elife. 2021;10: pubmed 出版商
Zhang Y, Wu N, Gan Schreier H, Xu F, Tuma Kellner S, Staffer S, et al. FATP4 inactivation in cultured macrophages attenuates M1- and ER stress-induced cytokine release via a metabolic shift towards triacylglycerides. Biochem J. 2021;478:1861-1877 pubmed 出版商
Rigby M, Lawton A, Kaur G, Banduseela V, Kamm W, Lakkaraju A, et al. Endoplasmic reticulum acetyltransferases Atase1 and Atase2 differentially regulate reticulophagy, macroautophagy and cellular acetyl-CoA metabolism. Commun Biol. 2021;4:454 pubmed 出版商
Pandey R, Bakay M, Strenkowski B, Hain H, Hakonarson H. JAK/STAT inhibitor therapy partially rescues the lipodystrophic autoimmune phenotype in Clec16a KO mice. Sci Rep. 2021;11:7372 pubmed 出版商
Parthibane V, Lin J, Acharya D, Abimannan T, Srideshikan S, Klarmann K, et al. SSSPTA is essential for serine palmitoyltransferase function during development and hematopoiesis. J Biol Chem. 2021;296:100491 pubmed 出版商
Chen N, Zhang Y, Wang M, Lin X, Li J, Li J, et al. Maternal obesity interrupts the coordination of the unfolded protein response and heat shock response in the postnatal developing hypothalamus of male offspring in mice. Mol Cell Endocrinol. 2021;527:111218 pubmed 出版商
Cao X, An J, Cao Y, Lv J, Wang J, Ding Y, et al. EMC3 Is Essential for Retinal Organization and Neurogenesis During Mouse Retinal Development. Invest Ophthalmol Vis Sci. 2021;62:31 pubmed 出版商
De Nisco N, Casey A, Kanchwala M, Lafrance A, Coskun F, Kinch L, et al. Manipulation of IRE1-Dependent MAPK Signaling by a Vibrio Agonist-Antagonist Effector Pair. mSystems. 2021;6: pubmed 出版商
Zhou L, Song Z, Hu J, Liu L, Hou Y, Zhang X, et al. ACSS3 represses prostate cancer progression through downregulating lipid droplet-associated protein PLIN3. Theranostics. 2021;11:841-860 pubmed 出版商
Kalish B, Kim E, Finander B, Duffy E, Kim H, Gilman C, et al. Maternal immune activation in mice disrupts proteostasis in the fetal brain. Nat Neurosci. 2021;24:204-213 pubmed 出版商
Bontemps Karcher A, Magneron V, Conquet L, Elie C, Gloaguen C, Kereselidze D, et al. Renal adaptive response to exposure to low doses of uranyl nitrate and sodium fluoride in mice. J Trace Elem Med Biol. 2021;64:126708 pubmed 出版商
Arioka Y, Shishido E, Kushima I, Suzuki T, Saito R, Aiba A, et al. Chromosome 22q11.2 deletion causes PERK-dependent vulnerability in dopaminergic neurons. EBioMedicine. 2021;63:103138 pubmed 出版商
Lanzillotta C, Zuliani I, Tramutola A, Barone E, Blarzino C, Folgiero V, et al. Chronic PERK induction promotes Alzheimer-like neuropathology in Down syndrome: Insights for therapeutic intervention. Prog Neurobiol. 2021;196:101892 pubmed 出版商
O Brien C, Santos P, Kulikowicz E, Lee J, Koehler R, Martin L. Neurologic effects of short-term treatment with a soluble epoxide hydrolase inhibitor after cardiac arrest in pediatric swine. BMC Neurosci. 2020;21:43 pubmed 出版商
Mello A, Hsu M, Koike S, Chu B, Cheng J, Yang J, et al. Soluble Epoxide Hydrolase Hepatic Deficiency Ameliorates Alcohol-Associated Liver Disease. Cell Mol Gastroenterol Hepatol. 2020;: pubmed 出版商
Xiong Z, Yuan C, Shi J, Xiong W, Huang Y, Xiao W, et al. Restoring the epigenetically silenced PCK2 suppresses renal cell carcinoma progression and increases sensitivity to sunitinib by promoting endoplasmic reticulum stress. Theranostics. 2020;10:11444-11461 pubmed 出版商
Chen Y, Griffiths A, Wang J, Zhang T, Song Q, Song Z. Inositol-requiring enzyme 1α links palmitate-induced mTOR activation and lipotoxicity in hepatocytes. Am J Physiol Cell Physiol. 2020;319:C1130-C1140 pubmed 出版商
Kim H, Cho Y, Kim H, Kang D, Cheon D, Kim Y, et al. A system-level approach identifies HIF-2α as a critical regulator of chondrosarcoma progression. Nat Commun. 2020;11:5023 pubmed 出版商
Ding R, Ou W, Chen C, Liu Y, Li H, Zhang X, et al. Endoplasmic reticulum stress and oxidative stress contribute to neuronal pyroptosis caused by cerebral venous sinus thrombosis in rats: Involvement of TXNIP/peroxynitrite-NLRP3 inflammasome activation. Neurochem Int. 2020;141:104856 pubmed 出版商
Zhao Q, Zhong J, Bi Y, Liu Y, Liu Y, Guo J, et al. Gambogenic acid induces Noxa-mediated apoptosis in colorectal cancer through ROS-dependent activation of IRE1α/JNK. Phytomedicine. 2020;78:153306 pubmed 出版商
Aryal Y, Lee E, Kim T, Sung S, Kim J, An S, et al. Stage-specific expression patterns of ER stress-related molecules in mice molars: Implications for tooth development. Gene Expr Patterns. 2020;37:119130 pubmed 出版商
Ganesan M, Mathews S, Makarov E, Petrosyan A, Kharbanda K, Kidambi S, et al. Acetaldehyde suppresses HBV-MHC class I complex presentation on hepatocytes via induction of ER stress and Golgi fragmentation. Am J Physiol Gastrointest Liver Physiol. 2020;319:G432-G442 pubmed 出版商
Winnay J, Solheim M, Sakaguchi M, Njølstad P, Kahn C. Inhibition of the PI 3-kinase pathway disrupts the unfolded protein response and reduces sensitivity to ER stress-dependent apoptosis. FASEB J. 2020;34:12521-12532 pubmed 出版商
Galeone A, Adams J, Matsuda S, Presa M, Pandey A, Han S, et al. Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation. elife. 2020;9: pubmed 出版商
Yue X, Sun X, Che K, Hu J, Lv W, Sun X, et al. Lpl-C310R mutation is associated with impaired glucose tolerance and endoplasmic reticulum stress in skeletal muscle. Biochem Biophys Res Commun. 2020;529:480-486 pubmed 出版商
Cicalese S, Okuno K, Elliott K, Kawai T, Scalia R, Rizzo V, et al. 78 kDa Glucose-Regulated Protein Attenuates Protein Aggregation and Monocyte Adhesion Induced by Angiotensin II in Vascular Cells. Int J Mol Sci. 2020;21: pubmed 出版商
Hotokezaka Y, Katayama I, Nakamura T. ATM-associated signalling triggers the unfolded protein response and cell death in response to stress. Commun Biol. 2020;3:378 pubmed 出版商
Murray H, Dieriks B, Swanson M, Anekal P, Turner C, Faull R, et al. The unfolded protein response is activated in the olfactory system in Alzheimer's disease. Acta Neuropathol Commun. 2020;8:109 pubmed 出版商
Zhao Y, Ma S, Cao M, Sun C. G604S-HERG mutation in LQT2 leads to autophagy via the UPR-related pathway. J Biosci. 2020;45: pubmed
Protto V, Tramutola A, Fabiani M, Marcocci M, Napoletani G, Iavarone F, et al. Multiple Herpes Simplex Virus-1 (HSV-1) Reactivations Induce Protein Oxidative Damage in Mouse Brain: Novel Mechanisms for Alzheimer's Disease Progression. Microorganisms. 2020;8: pubmed 出版商
Wu X, Deng M, Gao Z, Dang Y, Li Y, Li C. Neferine alleviates memory and cognitive dysfunction in diabetic mice through modulation of the NLRP3 inflammasome pathway and alleviation of endoplasmic-reticulum stress. Int Immunopharmacol. 2020;84:106559 pubmed 出版商
Li C, Deng M, Gao Z, Dang Y, Zheng G, Yang X, et al. Effects of compound K, a metabolite of ginsenosides, on memory and cognitive dysfunction in db/db mice involve the inhibition of ER stress and the NLRP3 inflammasome pathway. Food Funct. 2020;11:4416-4427 pubmed 出版商
Shimizu Y, Nakamura K, Yoshii A, Yokoi Y, Kikuchi M, Shinozaki R, et al. Paneth cell α-defensin misfolding correlates with dysbiosis and ileitis in Crohn's disease model mice. Life Sci Alliance. 2020;3: pubmed 出版商
Bellini L, Strub T, Habel N, Pandiani C, Marchetti S, Martel A, et al. Endoplasmic reticulum stress mediates resistance to BCL-2 inhibitor in uveal melanoma cells. Cell Death Discov. 2020;6:22 pubmed 出版商
Liu D, Zhang P, Zhou J, Liao R, Che Y, Gao M, et al. TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation. Cell Metab. 2020;31:726-740.e8 pubmed 出版商
Garufi A, Federici G, Gilardini Montani M, Crispini A, Cirone M, D Orazi G. Interplay between Endoplasmic Reticulum (ER) Stress and Autophagy Induces Mutant p53H273 Degradation. Biomolecules. 2020;10: pubmed 出版商
Hinte F, van Anken E, Tirosh B, Brune W. Repression of viral gene expression and replication by the unfolded protein response effector XBP1u. elife. 2020;9: pubmed 出版商
Liu X, Deng Y, Dai Z, Hu T, Cai W, Liu H, et al. Sodium tanshinone IIA sulfonate protects against Aβ1-42-induced cellular toxicity by modulating Aβ-degrading enzymes in HT22 cells. Int J Biol Macromol. 2020;151:47-55 pubmed 出版商
Woo M, Choi H, Park S, Ahn J, Jang Y, Ha T, et al. The unc-51 like autophagy activating kinase 1-autophagy related 13 complex has distinct functions in tunicamycin-treated cells. Biochem Biophys Res Commun. 2020;524:744-749 pubmed 出版商
Maeyashiki C, Melhem H, Hering L, Baebler K, Cosin Roger J, Schefer F, et al. Activation of pH-Sensing Receptor OGR1 (GPR68) Induces ER Stress Via the IRE1α/JNK Pathway in an Intestinal Epithelial Cell Model. Sci Rep. 2020;10:1438 pubmed 出版商
Han L, Bittner S, Dong D, Cortez Y, Bittner A, Chan J, et al. Molecular changes in hepatic metabolism in ZDSD rats-A new polygenic rodent model of obesity, metabolic syndrome, and diabetes. Biochim Biophys Acta Mol Basis Dis. 2020;1866:165688 pubmed 出版商
Yoshikawa Y, Sugimoto K, Ochiai Y, Ohashi N. Intracellular proliferation of Anaplasma phagocytophilum is promoted via modulation of endoplasmic reticulum stress signaling in host cells. Microbiol Immunol. 2020;64:270-279 pubmed 出版商
Wang M, LAW M, Davis B, Yaaghubi E, Ghilardi A, Ferreira R, et al. Disulfide bond-disrupting agents activate the tumor necrosis family-related apoptosis-inducing ligand/death receptor 5 pathway. Cell Death Discov. 2019;5:153 pubmed 出版商
Younan P, Santos R, Ramanathan P, Iampietro M, Nishida A, Dutta M, et al. Ebola virus-mediated T-lymphocyte depletion is the result of an abortive infection. PLoS Pathog. 2019;15:e1008068 pubmed 出版商
Yan C, Liu J, Gao J, Sun Y, Zhang L, Song H, et al. IRE1 promotes neurodegeneration through autophagy-dependent neuron death in the Drosophila model of Parkinson's disease. Cell Death Dis. 2019;10:800 pubmed 出版商
Gu R, Huang T, Xiao J, Liao Z, Li J, Lan H, et al. The IRE1α Arm of UPR Regulates Muscle Cells Immune Characters by Restraining p38 MAPK Activation. Front Physiol. 2019;10:1198 pubmed 出版商
Velazquez K, Enos R, Bader J, Sougiannis A, Carson M, Chatzistamou I, et al. Prolonged high-fat-diet feeding promotes non-alcoholic fatty liver disease and alters gut microbiota in mice. World J Hepatol. 2019;11:619-637 pubmed 出版商
Mu K, Sun Y, Zhao Y, Zhao T, Li Q, Zhang M, et al. Hepatic nitric oxide synthase 1 adaptor protein regulates glucose homeostasis and hepatic insulin sensitivity in obese mice depending on its PDZ binding domain. EBioMedicine. 2019;47:352-364 pubmed 出版商
Wiersma V, van Ziel A, Vazquez Sanchez S, Nölle A, Berenjeno Correa E, Bonaterra Pastra A, et al. Granulovacuolar degeneration bodies are neuron-selective lysosomal structures induced by intracellular tau pathology. Acta Neuropathol. 2019;138:943-970 pubmed 出版商
Ming Y, Zhu X, Tuma Kellner S, Ganzha A, Liebisch G, Gan Schreier H, et al. iPla2β Deficiency Suppresses Hepatic ER UPR, Fxr, and Phospholipids in Mice Fed with MCD Diet, Resulting in Exacerbated Hepatic Bile Acids and Biliary Cell Proliferation. Cells. 2019;8: pubmed 出版商
Comitato A, Schiroli D, Montanari M, Marigo V. Calpain Activation Is the Major Cause of Cell Death in Photoreceptors Expressing a Rhodopsin Misfolding Mutation. Mol Neurobiol. 2019;: pubmed 出版商
Xia Z, Wu S, Wei X, Liao Y, Yi P, Liu Y, et al. Hypoxic ER stress suppresses β-catenin expression and promotes cooperation between the transcription factors XBP1 and HIF1α for cell survival. J Biol Chem. 2019;294:13811-13821 pubmed 出版商
Shin G, Moon S, Kang H, Choi H, Han H, Kim K. PRKCSH contributes to tumorigenesis by selective boosting of IRE1 signaling pathway. Nat Commun. 2019;10:3185 pubmed 出版商
Han S, Mao L, Liao Y, Sun S, Zhang Z, Mo Y, et al. Sec62 Suppresses Foot-and-Mouth Disease Virus Proliferation by Promotion of IRE1α-RIG-I Antiviral Signaling. J Immunol. 2019;: pubmed 出版商
Inoue T, Yamakage H, Tanaka M, Kusakabe T, Shimatsu A, Satoh Asahara N. Oxytocin Suppresses Inflammatory Responses Induced by Lipopolysaccharide through Inhibition of the eIF-2-ATF4 Pathway in Mouse Microglia. Cells. 2019;8: pubmed 出版商
Naughton M, McMahon J, Healy S, FitzGerald U. Profile of the unfolded protein response in rat cerebellar cortical development. J Comp Neurol. 2019;527:2910-2924 pubmed 出版商
O Brien C, Santos P, Kulikowicz E, Reyes M, Koehler R, Martin L, et al. Hypoxia-Ischemia and Hypothermia Independently and Interactively Affect Neuronal Pathology in Neonatal Piglets with Short-Term Recovery. Dev Neurosci. 2019;:1-17 pubmed 出版商
Zheng W, Xie W, Yin D, Luo R, Liu M, Guo F. ATG5 and ATG7 induced autophagy interplays with UPR via PERK signaling. Cell Commun Signal. 2019;17:42 pubmed 出版商
Li H, O Meara M, Zhang X, Zhang K, Seyoum B, Yi Z, et al. Ameliorating Methylglyoxal-Induced Progenitor Cell Dysfunction for Tissue Repair in Diabetes. Diabetes. 2019;68:1287-1302 pubmed 出版商
Otto A, Gan Schreier H, Zhu X, Tuma Kellner S, Staffer S, Ganzha A, et al. Group VIA phospholipase A2 deficiency in mice chronically fed with high-fat-diet attenuates hepatic steatosis by correcting a defect of phospholipid remodeling. Biochim Biophys Acta Mol Cell Biol Lipids. 2019;1864:662-676 pubmed 出版商
Lee M, Bae S, Kim J, Song B, Choi J, Park J, et al. Inhibition of endoplasmic reticulum stress in high-fat-diet-induced obese C57BL/6 mice: Efficacy of a novel extract from mulberry (Morus alba) leaves fermented with Cordyceps militaris. Lab Anim Res. 2018;34:288-294 pubmed 出版商
Yang F, Liu Y, Ren H, Zhou G, Yuan X, Shi X. ER-stress regulates macrophage polarization through pancreatic EIF-2alpha kinase. Cell Immunol. 2019;336:40-47 pubmed 出版商
Wu C, Silvers C, Messing E, Lee Y. Bladder cancer extracellular vesicles drive tumorigenesis by inducing the unfolded protein response in endoplasmic reticulum of nonmalignant cells. J Biol Chem. 2019;294:3207-3218 pubmed 出版商
Sun M, Zhang J, Jiang L, Pan Y, Tan J, Yu F, et al. TMED2 Potentiates Cellular IFN Responses to DNA Viruses by Reinforcing MITA Dimerization and Facilitating Its Trafficking. Cell Rep. 2018;25:3086-3098.e3 pubmed 出版商
Aggarwal S, Ahmad I, Lam A, Carlisle M, Li C, Wells J, et al. Heme scavenging reduces pulmonary endoplasmic reticulum stress, fibrosis, and emphysema. JCI Insight. 2018;3: pubmed 出版商
Pramanik J, Chen X, Kar G, Henriksson J, Gomes T, Park J, et al. Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation. Genome Med. 2018;10:76 pubmed 出版商
Chang T, Lawrence D, Lu M, Tan J, Harnoss J, Marsters S, et al. Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate. Mol Cell. 2018;71:629-636.e5 pubmed 出版商
Cho Y, Kim D, Lee K, Jeong S, Kwon O. The IRE1α-XBP1s pathway promotes insulin-stimulated glucose uptake in adipocytes by increasing PPARγ activity. Exp Mol Med. 2018;50:102 pubmed 出版商
Fussi N, Höllerhage M, Chakroun T, Nykänen N, Rösler T, Koeglsperger T, et al. Exosomal secretion of ?-synuclein as protective mechanism after upstream blockage of macroautophagy. Cell Death Dis. 2018;9:757 pubmed 出版商
Yang F, Wang S, Liu Y, Zhou Y, Shang L, Feng M, et al. IRE1α aggravates ischemia reperfusion injury of fatty liver by regulating phenotypic transformation of kupffer cells. Free Radic Biol Med. 2018;124:395-407 pubmed 出版商
Zhang L, Cheng X, Xu S, Bao J, Yu H. Curcumin induces endoplasmic reticulum stress-associated apoptosis in human papillary thyroid carcinoma BCPAP cells via disruption of intracellular calcium homeostasis. Medicine (Baltimore). 2018;97:e11095 pubmed 出版商
Pommier A, Anaparthy N, Memos N, Kelley Z, Gouronnec A, Yan R, et al. Unresolved endoplasmic reticulum stress engenders immune-resistant, latent pancreatic cancer metastases. Science. 2018;360: pubmed 出版商
Steiger D, Yokota T, Li J, Ren S, Minamisawa S, Wang Y. The serine/threonine-protein kinase/endoribonuclease IRE1α protects the heart against pressure overload-induced heart failure. J Biol Chem. 2018;293:9652-9661 pubmed 出版商
Choi S, Snider J, Olakkengil N, Lambert J, Anderson A, Ross Evans J, et al. Myristate-induced endoplasmic reticulum stress requires ceramide synthases 5/6 and generation of C14-ceramide in intestinal epithelial cells. FASEB J. 2018;32:5724-5736 pubmed 出版商
Wang B, Su C, Liu T, Zhou Y, Feng Y, Huang Y, et al. The Neuroprotection of Low-Dose Morphine in Cellular and Animal Models of Parkinson's Disease Through Ameliorating Endoplasmic Reticulum (ER) Stress and Activating Autophagy. Front Mol Neurosci. 2018;11:120 pubmed 出版商
Kazama H, Hiramoto M, Miyahara K, Takano N, Miyazawa K. Designing an effective drug combination for ER stress loading in cancer therapy using a real-time monitoring system. Biochem Biophys Res Commun. 2018;501:286-292 pubmed 出版商
Bi X, Zhang G, Wang X, Nguyen C, May H, Li X, et al. Endoplasmic Reticulum Chaperone GRP78 Protects Heart From Ischemia/Reperfusion Injury Through Akt Activation. Circ Res. 2018;122:1545-1554 pubmed 出版商
Li C, Fan Q, Quan H, Nie M, Luo Y, Wang L. The three branches of the unfolded protein response exhibit differential significance in breast cancer growth and stemness. Exp Cell Res. 2018;367:170-185 pubmed 出版商
Niu X, Zhang J, Ling C, Bai M, Peng Y, Sun S, et al. Polysaccharide from Angelica sinensis protects H9c2 cells against oxidative injury and endoplasmic reticulum stress by activating the ATF6 pathway. J Int Med Res. 2018;46:1717-1733 pubmed 出版商
Crider A, Nelson T, Davis T, Fagan K, Vaibhav K, Luo M, et al. Estrogen Receptor β Agonist Attenuates Endoplasmic Reticulum Stress-Induced Changes in Social Behavior and Brain Connectivity in Mice. Mol Neurobiol. 2018;55:7606-7618 pubmed 出版商
Liu X, Guo G, Kong B, Hilburn D, Hubchak S, Park S, et al. Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice. Hepatology. 2018;68:304-316 pubmed 出版商
Amer S, Bhopale K, Kakumanu R, Popov V, Rampy B, El Mehallawi I, et al. Hepatic alcohol dehydrogenase deficiency induces pancreatic injury in chronic ethanol feeding model of deer mice. Exp Mol Pathol. 2018;104:89-97 pubmed 出版商
Porteiro B, Fondevila M, Buqué X, Gonzalez Rellan M, Fernandez U, Mora A, et al. Pharmacological stimulation of p53 with low-dose doxorubicin ameliorates diet-induced nonalcoholic steatosis and steatohepatitis. Mol Metab. 2018;8:132-143 pubmed 出版商
Ma L, Liu Y, Landry N, El Achkar T, Lieske J, Wu X. Point mutation in D8C domain of Tamm-Horsfall protein/uromodulin in transgenic mice causes progressive renal damage and hyperuricemia. PLoS ONE. 2017;12:e0186769 pubmed 出版商
Yasui T, Gomi H, Kitahara T, Tsukise A. Ultrastructure and immunohistochemical characterization of proteins concerned with the secretory machinery in goat ceruminous glands. Eur J Histochem. 2017;61:2828 pubmed 出版商
Ji C, Yang B, Huang S, Huang J, Cheng B. Salubrinal protects human skin fibroblasts against UVB-induced cell death by blocking endoplasmic reticulum (ER) stress and regulating calcium homeostasis. Biochem Biophys Res Commun. 2017;493:1371-1376 pubmed 出版商
Sun J, Ren D. IER3IP1 deficiency leads to increased ?-cell death and decreased ?-cell proliferation. Oncotarget. 2017;8:56768-56779 pubmed 出版商
Plaas M, Seppa K, Reimets R, Jagomäe T, Toots M, Koppel T, et al. Wfs1- deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration. Sci Rep. 2017;7:10220 pubmed 出版商
Zhang X, Wu W, Xu W, Man K, Wang X, Han J, et al. C-X-C Motif Chemokine 10 Impairs Autophagy and Autolysosome Formation in Non-alcoholic Steatohepatitis. Theranostics. 2017;7:2822-2836 pubmed 出版商
Zhang X, Wang X, Zhou Z, Bai H, Shi L, Yang Y, et al. The combination of digoxin and GSK2606414 exerts synergistic anticancer activity against leukemia in vitro and in vivo. Biofactors. 2017;43:812-820 pubmed 出版商
Rius B, Duran Güell M, Flores Costa R, López Vicario C, Lopategi A, Alcaraz Quiles J, et al. The specialized proresolving lipid mediator maresin 1 protects hepatocytes from lipotoxic and hypoxia-induced endoplasmic reticulum stress. FASEB J. 2017;31:5384-5398 pubmed 出版商
Guo H, Wang Y, Zhang X, Zang Y, Zhang Y, Wang L, et al. Astragaloside IV protects against podocyte injury via SERCA2-dependent ER stress reduction and AMPKα-regulated autophagy induction in streptozotocin-induced diabetic nephropathy. Sci Rep. 2017;7:6852 pubmed 出版商
Okumura N, Hashimoto K, Kitahara M, Okuda H, Ueda E, Watanabe K, et al. Activation of TGF-β signaling induces cell death via the unfolded protein response in Fuchs endothelial corneal dystrophy. Sci Rep. 2017;7:6801 pubmed 出版商
Nakazawa H, Ikeda K, Shinozaki S, Kobayashi M, Ikegami Y, Fu M, et al. Burn-induced muscle metabolic derangements and mitochondrial dysfunction are associated with activation of HIF-1α and mTORC1: Role of protein farnesylation. Sci Rep. 2017;7:6618 pubmed 出版商
Okumura N, Kitahara M, Okuda H, Hashimoto K, Ueda E, Nakahara M, et al. Sustained Activation of the Unfolded Protein Response Induces Cell Death in Fuchs' Endothelial Corneal Dystrophy. Invest Ophthalmol Vis Sci. 2017;58:3697-3707 pubmed 出版商
Alam S, Abdullah C, Aishwarya R, Orr A, Traylor J, Miriyala S, et al. Sigmar1 regulates endoplasmic reticulum stress-induced C/EBP-homologous protein expression in cardiomyocytes. Biosci Rep. 2017;37: pubmed 出版商
Tsai T, Chen E, Li L, Saha P, Lee H, Huang L, et al. The constitutive lipid droplet protein PLIN2 regulates autophagy in liver. Autophagy. 2017;13:1130-1144 pubmed 出版商
Shan B, Wang X, Wu Y, Xu C, Xia Z, Dai J, et al. The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity. Nat Immunol. 2017;18:519-529 pubmed 出版商
Duran Aniotz C, Cornejo V, Espinoza S, Ardiles A, Medinas D, Salazar C, et al. IRE1 signaling exacerbates Alzheimer's disease pathogenesis. Acta Neuropathol. 2017;134:489-506 pubmed 出版商
Mahmassani Z, Son K, Pincu Y, Munroe M, Drnevich J, Chen J, et al. α7β1 Integrin regulation of gene transcription in skeletal muscle following an acute bout of eccentric exercise. Am J Physiol Cell Physiol. 2017;312:C638-C650 pubmed 出版商
Teng R, Jing X, Michalkiewicz T, Afolayan A, Wu T, Konduri G. Attenuation of endoplasmic reticulum stress by caffeine ameliorates hyperoxia-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2017;312:L586-L598 pubmed 出版商
Guo H, Cao A, Chu S, Wang Y, Zang Y, Mao X, et al. Astragaloside IV Attenuates Podocyte Apoptosis Mediated by Endoplasmic Reticulum Stress through Upregulating Sarco/Endoplasmic Reticulum Ca2+-ATPase 2 Expression in Diabetic Nephropathy. Front Pharmacol. 2016;7:500 pubmed 出版商
Enos R, Velazquez K, Carson M, McClellan J, Nagarkatti P, Nagarkatti M, et al. A Low Dose of Dietary Quercetin Fails to Protect against the Development of an Obese Phenotype in Mice. PLoS ONE. 2016;11:e0167979 pubmed 出版商
Takatori O, Usui S, Okajima M, Kaneko S, Ootsuji H, Takashima S, et al. Sodium 4-Phenylbutyrate Attenuates Myocardial Reperfusion Injury by Reducing the Unfolded Protein Response. J Cardiovasc Pharmacol Ther. 2017;22:283-292 pubmed 出版商
Liu X, Zhao J, Liu Q, Xiong X, Zhang Z, Jiao Y, et al. MicroRNA-124 promotes hepatic triglyceride accumulation through targeting tribbles homolog 3. Sci Rep. 2016;6:37170 pubmed 出版商
Wiersma V, Van Hecke W, Scheper W, van Osch M, Hermsen W, Rozemuller A, et al. Activation of the unfolded protein response and granulovacuolar degeneration are not common features of human prion pathology. Acta Neuropathol Commun. 2016;4:113 pubmed
Bastola P, Neums L, Schoenen F, Chien J. VCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase-mediated cell death and synergistically kill ovarian cancer cells in combination with Salubrinal. Mol Oncol. 2016;10:1559-1574 pubmed 出版商
Zanotto Filho A, Masamsetti V, Loranc E, Tonapi S, Gorthi A, Bernard X, et al. Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis. Mol Cancer Ther. 2016;15:3000-3014 pubmed
Oka T, Kurozumi K, Shimazu Y, Ichikawa T, Ishida J, Otani Y, et al. A super gene expression system enhances the anti-glioma effects of adenovirus-mediated REIC/Dkk-3 gene therapy. Sci Rep. 2016;6:33319 pubmed 出版商
Xiao Y, Xia T, Yu J, Deng Y, Liu H, Liu B, et al. Knockout of inositol-requiring enzyme 1? in pro-opiomelanocortin neurons decreases fat mass via increasing energy expenditure. Open Biol. 2016;6: pubmed 出版商
Kishi H, Sato M, Shibata Y, Sato K, Inoue S, Abe S, et al. Role of chemokine C-C motif ligand-1 in acute and chronic pulmonary inflammations. Springerplus. 2016;5:1241 pubmed 出版商
Kwanten W, Vandewynckel Y, Martinet W, De Winter B, Michielsen P, Van Hoof V, et al. Hepatocellular autophagy modulates the unfolded protein response and fasting-induced steatosis in mice. Am J Physiol Gastrointest Liver Physiol. 2016;311:G599-G609 pubmed 出版商
Takatani T, Shirakawa J, Roe M, Leech C, Maier B, Mirmira R, et al. IRS1 deficiency protects ?-cells against ER stress-induced apoptosis by modulating sXBP-1 stability and protein translation. Sci Rep. 2016;6:28177 pubmed 出版商
Gao J, Zhang Y, Yu C, Tan F, Wang L. Spontaneous nonalcoholic fatty liver disease and ER stress in Sidt2 deficiency mice. Biochem Biophys Res Commun. 2016;476:326-332 pubmed 出版商
Cao A, Wang L, Chen X, Guo H, Chu S, Zhang X, et al. Ursodeoxycholic Acid Ameliorated Diabetic Nephropathy by Attenuating Hyperglycemia-Mediated Oxidative Stress. Biol Pharm Bull. 2016;39:1300-8 pubmed 出版商
Mandal A, Mandal S, Park M. Global quantitative proteomics reveal up-regulation of endoplasmic reticulum stress response proteins upon depletion of eIF5A in HeLa cells. Sci Rep. 2016;6:25795 pubmed 出版商
Ning B, Deng M, Zhang Q, Wang N, Fang Y. ?-Asarone Inhibits IRE1/XBP1 Endoplasmic Reticulum Stress Pathway in 6-OHDA-Induced Parkinsonian Rats. Neurochem Res. 2016;41:2097-101 pubmed 出版商
Merlot A, Shafie N, Yu Y, Richardson V, Jansson P, Sahni S, et al. Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase. Biochem Pharmacol. 2016;109:27-47 pubmed 出版商
Park M, Oh K, Nho J, Kim G, Kim D. Asymmetric dimethylarginine (ADMA) treatment induces apoptosis in cultured rat mesangial cells via endoplasmic reticulum stress activation. Cell Biol Int. 2016;40:662-70 pubmed 出版商
Soeda J, Mouralidarane A, Cordero P, Li J, Nguyen V, Carter R, et al. Maternal obesity alters endoplasmic reticulum homeostasis in offspring pancreas. J Physiol Biochem. 2016;72:281-91 pubmed 出版商
Kang K, Tarchick M, Yu X, Beight C, Bu P, Yu M. Carnosic acid slows photoreceptor degeneration in the Pde6b(rd10) mouse model of retinitis pigmentosa. Sci Rep. 2016;6:22632 pubmed 出版商
Aumailley L, Warren A, Garand C, Dubois M, Paquet E, Le Couteur D, et al. Vitamin C modulates the metabolic and cytokine profiles, alleviates hepatic endoplasmic reticulum stress, and increases the life span of Gulo-/- mice. Aging (Albany NY). 2016;8:458-83 pubmed
Hong M, Nam K, Kim K, Kim S, Kim I. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016;21:485-97 pubmed 出版商
Hong K, Xu G, Grayson T, Shalev A. Cytokines Regulate β-Cell Thioredoxin-interacting Protein (TXNIP) via Distinct Mechanisms and Pathways. J Biol Chem. 2016;291:8428-39 pubmed 出版商
Li Y, Zalzala M, Jadhav K, Xu Y, Kasumov T, Yin L, et al. Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice. Hepatology. 2016;63:1860-74 pubmed 出版商
Stijnen P, Brouwers B, Dirkx E, Ramos Molina B, Van Lommel L, Schuit F, et al. Endoplasmic reticulum-associated degradation of the mouse PC1/3-N222D hypomorph and human PCSK1 mutations contributes to obesity. Int J Obes (Lond). 2016;40:973-81 pubmed 出版商
Tao K, Wang B, Feng D, Zhang W, Lu F, Lai J, et al. Salidroside Protects Against 6-Hydroxydopamine-Induced Cytotoxicity by Attenuating ER Stress. Neurosci Bull. 2016;32:61-9 pubmed 出版商
Tampakakis E, Tabit C, Holbrook M, Linder E, Berk B, Frame A, et al. Intravenous Lipid Infusion Induces Endoplasmic Reticulum Stress in Endothelial Cells and Blood Mononuclear Cells of Healthy Adults. J Am Heart Assoc. 2016;5: pubmed 出版商
López González I, Pérez Mediavilla A, Zamarbide M, Carmona M, Torrejón Escribano B, Glatzel M, et al. Limited Unfolded Protein Response and Inflammation in Neuroserpinopathy. J Neuropathol Exp Neurol. 2016;75:121-33 pubmed
Vannuvel K, Van Steenbrugge M, Demazy C, Ninane N, Fattaccioli A, Fransolet M, et al. Effects of a Sublethal and Transient Stress of the Endoplasmic Reticulum on the Mitochondrial Population. J Cell Physiol. 2016;231:1913-31 pubmed 出版商
El Khattouti A, Selimovic D, Hannig M, Taylor E, Abd Elmageed Z, Hassan S, et al. Imiquimod-induced apoptosis of melanoma cells is mediated by ER stress-dependent Noxa induction and enhanced by NF-κB inhibition. J Cell Mol Med. 2016;20:266-86 pubmed 出版商
Kim O, Nam D, Jun W, Lee J. Cudrania tricuspidata water extract improved obesity-induced hepatic insulin resistance in db/db mice by suppressing ER stress and inflammation. Food Nutr Res. 2015;59:29165 pubmed 出版商
Jensen B, Monnerie H, Mannell M, Gannon P, Espinoza C, Erickson M, et al. Altered Oligodendrocyte Maturation and Myelin Maintenance: The Role of Antiretrovirals in HIV-Associated Neurocognitive Disorders. J Neuropathol Exp Neurol. 2015;74:1093-118 pubmed 出版商
Aumailley L, Garand C, Dubois M, Johnson F, Marette A, Lebel M. Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice. PLoS ONE. 2015;10:e0140292 pubmed 出版商
Concha N, Smallwood A, Bonnette W, Totoritis R, Zhang G, Federowicz K, et al. Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1α Endoribonuclease Activity. Mol Pharmacol. 2015;88:1011-23 pubmed 出版商
Gao X, van der Veen J, Vance J, Thiesen A, Vance D, Jacobs R. Lack of phosphatidylethanolamine N-methyltransferase alters hepatic phospholipid composition and induces endoplasmic reticulum stress. Biochim Biophys Acta. 2015;1852:2689-99 pubmed 出版商
Cai X, Chen L, McGinnis J. Correlation of ER stress and retinal degeneration in tubby mice. Exp Eye Res. 2015;140:130-138 pubmed 出版商
Wang Y, Yamada E, Zong H, Pessin J. Fyn Activation of mTORC1 Stimulates the IRE1α-JNK Pathway, Leading to Cell Death. J Biol Chem. 2015;290:24772-83 pubmed 出版商
Naughton M, McMahon J, FitzGerald U. Differential activation of ER stress pathways in myelinating cerebellar tracts. Int J Dev Neurosci. 2015;47:347-60 pubmed 出版商
Wang Y, Kuramitsu Y, Baron B, Kitagawa T, Akada J, Tokuda K, et al. PERK/CHOP contributes to the CGK733-induced vesicular calcium sequestration which is accompanied by non-apoptotic cell death. Oncotarget. 2015;6:25252-65 pubmed 出版商
Ma H, Butler M, Thapa A, Belcher J, Yang F, Baehr W, et al. cGMP/Protein Kinase G Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of Cyclic Nucleotide-gated Channel-deficient Mice. J Biol Chem. 2015;290:20880-92 pubmed 出版商
Quan X, Wang J, Liang C, Zheng H, Zhang L. Melatonin inhibits tunicamycin-induced endoplasmic reticulum stress and insulin resistance in skeletal muscle cells. Biochem Biophys Res Commun. 2015;463:1102-7 pubmed 出版商
Bi X, He X, Xu M, Zhao M, Yu X, Lu X, et al. Acetylcholine ameliorates endoplasmic reticulum stress in endothelial cells after hypoxia/reoxygenation via M3 AChR-AMPK signaling. Cell Cycle. 2015;14:2461-72 pubmed 出版商
Hrincius E, Liedmann S, Finkelstein D, Vogel P, Gansebom S, Samarasinghe A, et al. Acute Lung Injury Results from Innate Sensing of Viruses by an ER Stress Pathway. Cell Rep. 2015;11:1591-603 pubmed 出版商
Liang L, Chen J, Zhan L, Lu X, Sun X, Sui H, et al. Endoplasmic reticulum stress impairs insulin receptor signaling in the brains of obese rats. PLoS ONE. 2015;10:e0126384 pubmed 出版商
Borsa M, Ferreira P, Petry A, Ferreira L, Camargo M, Bou Habib D, et al. HIV infection and antiretroviral therapy lead to unfolded protein response activation. Virol J. 2015;12:77 pubmed 出版商
Jahng J, Turdi S, Kovacevic V, Dadson K, Li R, Sweeney G. Pressure Overload-Induced Cardiac Dysfunction in Aged Male Adiponectin Knockout Mice Is Associated With Autophagy Deficiency. Endocrinology. 2015;156:2667-77 pubmed 出版商
Shen Y, Yang J, Zhao J, Xiao C, Xu C, Xiang Y. The switch from ER stress-induced apoptosis to autophagy via ROS-mediated JNK/p62 signals: A survival mechanism in methotrexate-resistant choriocarcinoma cells. Exp Cell Res. 2015;334:207-18 pubmed 出版商
Hotokezaka Y, Katayama I, van Leyen K, Nakamura T. GSK-3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses. Cell Death Dis. 2015;6:e1719 pubmed 出版商
Qiu B, Ackerman D, Sanchez D, Li B, Ochocki J, Grazioli A, et al. HIF2α-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma. Cancer Discov. 2015;5:652-67 pubmed 出版商
Narsale A, Enos R, Puppa M, Chatterjee S, Murphy E, Fayad R, et al. Liver inflammation and metabolic signaling in ApcMin/+ mice: the role of cachexia progression. PLoS ONE. 2015;10:e0119888 pubmed 出版商
Jeon Y, Khelifa S, Ratnikov B, Scott D, Feng Y, Parisi F, et al. Regulation of glutamine carrier proteins by RNF5 determines breast cancer response to ER stress-inducing chemotherapies. Cancer Cell. 2015;27:354-69 pubmed 出版商
Iwasaki N, Sugiyama Y, Miyazaki S, Nakagawa H, Nishimura K, Matsuo S. An ATF4-Signal-Modulating Machine Other Than GADD34 Acts in ATF4-to-CHOP Signaling to Block CHOP Expression in ER-Stress-Related Autophagy. J Cell Biochem. 2015;116:1300-9 pubmed 出版商
Wu H, Wei L, Fan F, Ji S, Zhang S, Geng J, et al. Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis. Nat Commun. 2015;6:6239 pubmed 出版商
Walter F, Schmid J, Düssmann H, Concannon C, Prehn J. Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival. Cell Death Differ. 2015;22:1502-16 pubmed 出版商
Clarke J, Lyra e Silva N, Figueiredo C, Frozza R, Ledo J, Beckman D, et al. Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation. EMBO Mol Med. 2015;7:190-210 pubmed 出版商
Jaishy B, Zhang Q, Chung H, Riehle C, Soto J, Jenkins S, et al. Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity. J Lipid Res. 2015;56:546-61 pubmed 出版商
Kim D, Park M, Choi J, Lim S, Choi H, Park S. Hyperglycemia-induced GLP-1R downregulation causes RPE cell apoptosis. Int J Biochem Cell Biol. 2015;59:41-51 pubmed 出版商
Yang Y, Sun M, Shan Y, Zheng X, Ma H, Ma W, et al. Endoplasmic reticulum stress-mediated apoptotic pathway is involved in corpus luteum regression in rats. Reprod Sci. 2015;22:572-84 pubmed 出版商
产品信息
品牌 :
Novus
MasterCode :
NB100-2323
SKU号 :
NB100-2323
产品名称 :
IRE1 alpha [p Ser724] Antibody - BSA Free
描述 :
The IRE1 alpha [p Ser724] Antibody - BSA Free from NB100-2323 is a nb100-2323 antibody to . This antibody reacts with angiogenesis, apoptosis, cancer, diabetes research, hypoxia, lipid and metabolism, neurodegeneration, neuroscience, signal transduction, unfolded protein response.
靶标 :
IRE1甲
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1.0毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
This IRE1 alpha [p Ser724] antibody was raised against a synthetic peptide surrounding the phosphorylated serine 724 of the human IRE1 alpha protein. [Swiss-Prot #O75460]
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
Human, Mouse, Rat, Porcine, Drosophila, Goat, Mammal, Monkey, Primate, Rabbit, Golden Syrian Hamster
特异性 :
NB100-2323 IRE1 alpha [p Ser724] Antibody detects IRE-1 alpha when phosphorylated at Ser724 residue
理论上的分子量 :
110 kDa
基因符号 :
ERN1
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Immunohistochemistry-NB100-2323-img0031.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Immunohistochemistry-NB100-2323-img0031.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Immunohistochemistry-NB100-2323-img0031.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0027.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0027.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0027.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0029.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0029.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0029.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0021.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0021.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0021.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0024.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0024.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0024.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0030.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0030.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0030.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0032.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0032.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0032.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0022.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0022.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Western-Blot-NB100-2323-img0022.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Immunohistochemistry-Paraffin-NB100-2323-img0025.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Immunohistochemistry-Paraffin-NB100-2323-img0025.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-[p-Ser724]-Antibody-Immunohistochemistry-Paraffin-NB100-2323-img0025.jpg
应用 :
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, In vitro assay, Chromatin Immunoprecipitation (ChIP), Knockdown Validated
美元 :
449美元
别名 :
EC 2.7.11, endoplasmic reticulum to nucleus signaling 1, Endoplasmic reticulum-to-nucleus signaling 1, ER to nucleus signalling 1, FLJ30999, hIRE1p, inositol-requiring 1, Inositol-requiring protein 1, IRE 1a, ire1 alpha p Ser724, ire1 alpha phosphorylation, IRE1a, ire1-alpha, IRE1MGC163279, IRE1P, MGC163277, phospho ire1 alpha, phospho-ire1 alpha, phospho-ire1a, p-ire1 alpha, protein kinase/endoribonuclease, serine/threonine-protein kinase/endoribonuclease IRE1
储存 :
分成小份儿保存在-20C或-80C。 避免冻融循环
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。