产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
IRE1甲抗体
目录 :
NB100-2324
规格 :
0.1 ml (also 0.025 ml)
价格 :
399美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
DyLight488
克隆名称 :
711-66
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 37
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:500; 图 6e
Wang Y, Lee Y, Hsu Y, Chiu I, Huang C, Huang C, et al. The Kidney-Related Effects of Polystyrene Microplastics on Human Kidney Proximal Tubular Epithelial Cells HK-2 and Male C57BL/6 Mice. Environ Health Perspect. 2021;129:57003 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7
Alnasser H, Guan Q, Zhang F, Gleave M, Nguan C, Du C. Requirement of clusterin expression for prosurvival autophagy in hypoxic kidney tubular epithelial cells. Am J Physiol Renal Physiol. 2016;310:F160-73 pubmed 出版商
Wu D, Zhang X, Zimmerly K, Wang R, Livingston A, Iwawaki T, et al. Unconventional Activation of IRE1 Enhances TH17 Responses and Promotes Neutrophilic Airway Inflammation. bioRxiv. 2023;: pubmed 出版商
Espina M, Di Franco N, Bra xf1 as Navarro M, Navarro I, Brito V, López Molina L, et al. The GRP78-PERK axis contributes to memory and synaptic impairments in Huntington's disease R6/1 mice. Neurobiol Dis. 2023;184:106225 pubmed 出版商
Xiao J, Huang J, Jian X, Wang H, Lan H, Liao Z, et al. IRE1α arm of unfolded protein response in muscle-specific TGF-β signaling-mediated regulation of muscle cell immunological properties. Cell Mol Biol Lett. 2023;28:15 pubmed 出版商
Chakraborty S, Basu A. miR-451a Regulates Neuronal Apoptosis by Modulating 14-3-3ζ-JNK Axis upon Flaviviral Infection. mSphere. 2022;7:e0020822 pubmed 出版商
Li Q, Fan X, Lu W, Sun C, Pei Z, Zhang M, et al. Novel NPR2 Gene Mutations Affect Chondrocytes Function via ER Stress in Short Stature. Cells. 2022;11: pubmed 出版商
Srinivasan M, Bhopale K, Caracheo A, Kaphalia L, Gong B, Popov V, et al. Exposure to binge ethanol and fatty acid ethyl esters exacerbates chronic ethanol-induced pancreatic injury in hepatic alcohol dehydrogenase-deficient deer mice. Am J Physiol Gastrointest Liver Physiol. 2022;322:G327-G345 pubmed 出版商
Huang L, Liu Q, Zhou T, Zhang J, Tian Q, Zhang Q, et al. Deficiency of β-arrestin2 alleviates apoptosis through GRP78-ATF6-CHOP signaling pathway in primary Sjögren's syndrome. Int Immunopharmacol. 2021;101:108281 pubmed 出版商
EINSTEIN J, Perelis M, Chaim I, Meena J, Nussbacher J, Tankka A, et al. Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer. Mol Cell. 2021;81:3048-3064.e9 pubmed 出版商
Qu Z, Lu X, Qu Y, Tao T, Liu X, Li X. Attenuation of the upregulation of NF‑κB and AP‑1 DNA‑binding activities induced by tunicamycin or hypoxia/reoxygenation in neonatal rat cardiomyocytes by SERCA2a overexpression. Int J Mol Med. 2021;47: pubmed 出版商
Pandey R, Bakay M, Strenkowski B, Hain H, Hakonarson H. JAK/STAT inhibitor therapy partially rescues the lipodystrophic autoimmune phenotype in Clec16a KO mice. Sci Rep. 2021;11:7372 pubmed 出版商
Ding R, Ou W, Chen C, Liu Y, Li H, Zhang X, et al. Endoplasmic reticulum stress and oxidative stress contribute to neuronal pyroptosis caused by cerebral venous sinus thrombosis in rats: Involvement of TXNIP/peroxynitrite-NLRP3 inflammasome activation. Neurochem Int. 2020;141:104856 pubmed 出版商
Srinivasan M, Bhopale K, Caracheo A, Amer S, Khan S, Kaphalia L, et al. Activation of AMP-activated protein kinase attenuates ethanol-induced ER/oxidative stress and lipid phenotype in human pancreatic acinar cells. Biochem Pharmacol. 2020;180:114174 pubmed 出版商
Cicalese S, Okuno K, Elliott K, Kawai T, Scalia R, Rizzo V, et al. 78 kDa Glucose-Regulated Protein Attenuates Protein Aggregation and Monocyte Adhesion Induced by Angiotensin II in Vascular Cells. Int J Mol Sci. 2020;21: pubmed 出版商
Garufi A, Federici G, Gilardini Montani M, Crispini A, Cirone M, D Orazi G. Interplay between Endoplasmic Reticulum (ER) Stress and Autophagy Induces Mutant p53H273 Degradation. Biomolecules. 2020;10: pubmed 出版商
Han L, Bittner S, Dong D, Cortez Y, Bittner A, Chan J, et al. Molecular changes in hepatic metabolism in ZDSD rats-A new polygenic rodent model of obesity, metabolic syndrome, and diabetes. Biochim Biophys Acta Mol Basis Dis. 2020;1866:165688 pubmed 出版商
Xie W, Xie J, Vince R, More S. Guanabenz Attenuates Acetaminophen-Induced Liver Toxicity and Synergizes Analgesia in Mice. Chem Res Toxicol. 2020;33:162-171 pubmed 出版商
Schmit K, Chen J, Ayama Canden S, Fransolet M, Finet L, Demazy C, et al. Characterization of the role of TMEM45A in cancer cell sensitivity to cisplatin. Cell Death Dis. 2019;10:919 pubmed 出版商
Gu R, Huang T, Xiao J, Liao Z, Li J, Lan H, et al. The IRE1α Arm of UPR Regulates Muscle Cells Immune Characters by Restraining p38 MAPK Activation. Front Physiol. 2019;10:1198 pubmed 出版商
Srinivasan M, Bhopale K, Amer S, Wan J, Kaphalia L, Ansari G, et al. Linking Dysregulated AMPK Signaling and ER Stress in Ethanol-Induced Liver Injury in Hepatic Alcohol Dehydrogenase Deficient Deer Mice. Biomolecules. 2019;9: pubmed 出版商
Park S, Kim Y, Yang S, Henderson M, Yang W, Lindahl M, et al. Discovery of endoplasmic reticulum calcium stabilizers to rescue ER-stressed podocytes in nephrotic syndrome. Proc Natl Acad Sci U S A. 2019;: pubmed 出版商
Kaphalia L, Srinivasan M, Kakumanu R, Kaphalia B, Calhoun W. Ethanol Exposure Impairs AMPK Signaling and Phagocytosis in Human Alveolar Macrophages: Role of Ethanol Metabolism. Alcohol Clin Exp Res. 2019;43:1682-1694 pubmed 出版商
Inoue T, Yamakage H, Tanaka M, Kusakabe T, Shimatsu A, Satoh Asahara N. Oxytocin Suppresses Inflammatory Responses Induced by Lipopolysaccharide through Inhibition of the eIF-2-ATF4 Pathway in Mouse Microglia. Cells. 2019;8: pubmed 出版商
Serrano R, Yu W, Graham R, Bryan R, Terkeltaub R. A vascular smooth muscle cell X-box binding protein 1 and transglutaminase 2 regulatory circuit limits neointimal hyperplasia. PLoS ONE. 2019;14:e0212235 pubmed 出版商
Hsu Y, Chuang H, Lee Y, Lin Y, Chen Y, Hsiao T, et al. Traffic-related particulate matter exposure induces nephrotoxicity in vitro and in vivo. Free Radic Biol Med. 2019;135:235-244 pubmed 出版商
Lee M, Bae S, Kim J, Song B, Choi J, Park J, et al. Inhibition of endoplasmic reticulum stress in high-fat-diet-induced obese C57BL/6 mice: Efficacy of a novel extract from mulberry (Morus alba) leaves fermented with Cordyceps militaris. Lab Anim Res. 2018;34:288-294 pubmed 出版商
Bretón Romero R, Weisbrod R, Feng B, Holbrook M, Ko D, Stathos M, et al. Liraglutide Treatment Reduces Endothelial Endoplasmic Reticulum Stress and Insulin Resistance in Patients With Diabetes Mellitus. J Am Heart Assoc. 2018;7:e009379 pubmed 出版商
Cho Y, Kim D, Lee K, Jeong S, Kwon O. The IRE1α-XBP1s pathway promotes insulin-stimulated glucose uptake in adipocytes by increasing PPARγ activity. Exp Mol Med. 2018;50:102 pubmed 出版商
Yang F, Wang S, Liu Y, Zhou Y, Shang L, Feng M, et al. IRE1α aggravates ischemia reperfusion injury of fatty liver by regulating phenotypic transformation of kupffer cells. Free Radic Biol Med. 2018;124:395-407 pubmed 出版商
Tripathi M, Zhang C, Singh B, Sinha R, Moe K, DeSilva D, et al. Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation. Cell Death Dis. 2016;7:e2513 pubmed 出版商
Li Y, Zalzala M, Jadhav K, Xu Y, Kasumov T, Yin L, et al. Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice. Hepatology. 2016;63:1860-74 pubmed 出版商
Kim O, Jun W, Lee J. Effect of Cudrania tricuspidata and Kaempferol in Endoplasmic Reticulum Stress-Induced Inflammation and Hepatic Insulin Resistance in HepG2 Cells. Nutrients. 2016;8: pubmed 出版商
Vannuvel K, Van Steenbrugge M, Demazy C, Ninane N, Fattaccioli A, Fransolet M, et al. Effects of a Sublethal and Transient Stress of the Endoplasmic Reticulum on the Mitochondrial Population. J Cell Physiol. 2016;231:1913-31 pubmed 出版商
Quan X, Wang J, Liang C, Zheng H, Zhang L. Melatonin inhibits tunicamycin-induced endoplasmic reticulum stress and insulin resistance in skeletal muscle cells. Biochem Biophys Res Commun. 2015;463:1102-7 pubmed 出版商
Clarke J, Lyra e Silva N, Figueiredo C, Frozza R, Ledo J, Beckman D, et al. Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation. EMBO Mol Med. 2015;7:190-210 pubmed 出版商
Ghosh A, Garg S, Mau T, O Brien M, Liu J, Yung R. Elevated Endoplasmic Reticulum Stress Response Contributes to Adipose Tissue Inflammation in Aging. J Gerontol A Biol Sci Med Sci. 2015;70:1320-9 pubmed 出版商
产品信息
品牌 :
Novus
MasterCode :
NB100-2324
SKU号 :
NB100-2324
产品名称 :
IRE1甲抗体
描述 :
The IRE1 alpha Antibody from NB100-2324 is a nb100-2324 antibody to . This antibody reacts with angiogenesis, apoptosis, cancer, diabetes research, hypoxia, lipid and metabolism, neurodegeneration, neuroscience, signal transduction, unfolded protein response.
靶标 :
IRE1甲
类别 :
一抗
单位尺寸 :
0.1 ml (also 0.025 ml)
缓冲液 :
三羟甲基氨基甲烷甘氨酸, 0.15M氯化钠
克隆性 :
多克隆
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
This IRE1 alpha antibody was raised against a synthetic peptide within the human IRE1 alpha protein (within residues 700-800). [Swiss-Prot #O75460]
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
人类, 小鼠, 大鼠
理论上的分子量 :
110 kDa
基因符号 :
ERN1
images :
https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-Antibody-Immunohistochemistry-NB100-2324-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-Antibody-Immunohistochemistry-NB100-2324-img0010.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-Antibody-Western-Blot-NB100-2324-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-Antibody-Western-Blot-NB100-2324-img0006.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-Antibody-Western-Blot-NB100-2324-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-Antibody-Western-Blot-NB100-2324-img0009.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-Antibody-Immunocytochemistry-Immunofluorescence-NB100-2324-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-Antibody-Immunocytochemistry-Immunofluorescence-NB100-2324-img0005.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-Antibody-Immunohistochemistry-Paraffin-NB100-2324-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-Antibody-Immunohistochemistry-Paraffin-NB100-2324-img0007.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-Antibody-Immunohistochemistry-Paraffin-NB100-2324-img0008.jpg, https://aeroglobalimagesprod.blob.core.windows.net/images/datasheets/IRE1-alpha-Antibody-Immunohistochemistry-Paraffin-NB100-2324-img0008.jpg
应用 :
免疫印迹, 免疫组化, 免疫细胞化学/免疫荧光, 免疫组化石蜡, 基因敲除验证, 基因敲减验证
美元 :
399美元
别名 :
EC 2.7.11, endoplasmic reticulum to nucleus signaling 1, Endoplasmic reticulum-to-nucleus signaling 1, ER to nucleus signalling 1, FLJ30999, hIRE1p, inositol-requiring 1, Inositol-requiring protein 1, IRE 1a, IRE1a, Ire1-alpha, IRE1MGC163279, IRE1P, MGC163277, protein kinase/endoribonuclease, serine/threonine-protein kinase/endoribonuclease IRE1
储存 :
存放在-20C。 避免冻融循环
更多信息或购买 :
公司信息
Novus Biologicals
10771 E Easter Ave
Centennial, CO 80112
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。