出版应用/物种/样本/稀释 | 参考文献 |
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- 免疫组化-冰冻切片; 小鼠; 1:100; 图 10a
- 免疫印迹; 小鼠; 1:500; 图 10b
| Venugopalan V, Al Hashimi A, Rehders M, Golchert J, Reinecke V, Homuth G, et al. The Thyroid Hormone Transporter Mct8 Restricts Cathepsin-Mediated Thyroglobulin Processing in Male Mice through Thyroid Auto-Regulatory Mechanisms That Encompass Autophagy. Int J Mol Sci. 2021;22: pubmed 出版商
|
| Watanabe S, Komine O, Endo F, Wakasugi K, Yamanaka K. Intracerebroventricular administration of Cystatin C ameliorates disease in SOD1-linked amyotrophic lateral sclerosis mice. J Neurochem. 2018;145:80-89 pubmed 出版商
|
| Suzuki J, Nakajima W, Suzuki H, Asano Y, Tanaka N. Chaperone-mediated autophagy promotes lung cancer cell survival through selective stabilization of the pro-survival protein, MCL1. Biochem Biophys Res Commun. 2017;482:1334-1340 pubmed 出版商
|
| Hossini A, Quast A, Plötz M, Grauel K, Exner T, Küchler J, et al. PI3K/AKT Signaling Pathway Is Essential for Survival of Induced Pluripotent Stem Cells. PLoS ONE. 2016;11:e0154770 pubmed 出版商
|
- 免疫组化-石蜡切片; 人类; 1:200; 表 2
| Piras A, Collin L, Grüninger F, Graff C, Rönnbäck A. Autophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supranuclear palsy. Acta Neuropathol Commun. 2016;4:22 pubmed 出版商
|
| Jacob F, Yonis A, Cuello F, Luther P, Schulze T, Eder A, et al. Analysis of Tyrosine Kinase Inhibitor-Mediated Decline in Contractile Force in Rat Engineered Heart Tissue. PLoS ONE. 2016;11:e0145937 pubmed 出版商
|
| Bühler A, Kustermann M, Bummer T, Rottbauer W, Sandri M, Just S. Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish. Int J Mol Sci. 2016;17: pubmed 出版商
|
| Li W, Zou J, Yue F, Song K, Chen Q, McKeehan W, et al. Defects in MAP1S-mediated autophagy cause reduction in mouse lifespans especially when fibronectin is overexpressed. Aging Cell. 2016;15:370-9 pubmed 出版商
|
| GarcÃa Prat L, MartÃnez Vicente M, Perdiguero E, Ortet L, RodrÃguez Ubreva J, Rebollo E, et al. Autophagy maintains stemness by preventing senescence. Nature. 2016;529:37-42 pubmed 出版商
|
| Kocaturk N, Peker N, Eberhart K, Akkoç Y, Deveci G, Dengjel J, et al. Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy. Cell Death Dis. 2022;13:947 pubmed 出版商
|
| Cui Y, Guo H, Zhang Q, Fang J, Xie Y, Chen S, et al. The combination of high glucose and LPS induces autophagy in bovine kidney epithelial cells via the Notch3/mTOR signaling pathway. BMC Vet Res. 2022;18:307 pubmed 出版商
|
| Jiang R, Smailovic U, Haytural H, Tijms B, Li H, Haret R, et al. Increased CSF-decorin predicts brain pathological changes driven by Alzheimer's Aβ amyloidosis. Acta Neuropathol Commun. 2022;10:96 pubmed 出版商
|
| Akkoç Y, Dalci K, Karakas H, Erbil Bilir S, Yalav O, Sakman G, et al. Tumor-derived CTF1 (cardiotrophin 1) is a critical mediator of stroma-assisted and autophagy-dependent breast cancer cell migration, invasion and metastasis. Autophagy. 2022;:1-18 pubmed 出版商
|
| Jiang R, Shimozawa M, Mayer J, Tambaro S, Kumar R, Abelein A, et al. Autophagy Impairment in App Knock-in Alzheimer's Model Mice. Front Aging Neurosci. 2022;14:878303 pubmed 出版商
|
| Record M, Attia M, Carayon K, Pucheu L, Buñay J, Soul xe8 s R, et al. Targeting the liver X receptor with dendrogenin A differentiates tumour cells to secrete immunogenic exosome-enriched vesicles. J Extracell Vesicles. 2022;11:e12211 pubmed 出版商
|
| Gawande D, S Narasimhan K, Bhatt J, Pavuluri R, Kesherwani V, Suryavanshi P, et al. Glutamate delta 1 receptor regulates autophagy mechanisms and affects excitatory synapse maturation in the somatosensory cortex. Pharmacol Res. 2022;178:106144 pubmed 出版商
|
| Abdelrahman R, El Tanbouly G. Protocatechuic acid protects against thioacetamide-induced chronic liver injury and encephalopathy in mice via modulating mTOR, p53 and the IL-6/ IL-17/ IL-23 immunoinflammatory pathway. Toxicol Appl Pharmacol. 2022;440:115931 pubmed 出版商
|
| Yin R, Wang H, Li C, Wang L, Lai S, Yang X, et al. Induction of apoptosis and autosis in cardiomyocytes by the combination of homocysteine and copper via NOX-mediated p62 expression. Cell Death Discov. 2022;8:75 pubmed 出版商
|
| Xu Z, Fu T, Guo Q, Zhou D, Sun W, Zhou Z, et al. Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength. Nat Commun. 2022;13:894 pubmed 出版商
|
| Lee H, Kwon Y, Jin H, Liu H, Kang W, Chun Y, et al. Anticancer activity and metabolic profile alterations by ortho-topolin riboside in in vitro and in vivo models of non-small cell lung cancer. FASEB J. 2022;36:e22127 pubmed 出版商
|
| Asare P, Tran H, Hurtado P, Perkins G, Nguyen P, Jersmann H, et al. Inhibition of LC3-associated phagocytosis in COPD and in response to cigarette smoke. Ther Adv Respir Dis. 2021;15:17534666211039769 pubmed 出版商
|
| Lu J, Zhong C, Luo J, Shu F, Lv D, Liu Z, et al. HnRNP-L-regulated circCSPP1/miR-520h/EGR1 axis modulates autophagy and promotes progression in prostate cancer. Mol Ther Nucleic Acids. 2021;26:927-944 pubmed 出版商
|
| Nurmi K, Niemi K, Kareinen I, Silventoinen K, Lorey M, Chen Y, et al. Native and oxidised lipoproteins negatively regulate the serum amyloid A-induced NLRP3 inflammasome activation in human macrophages. Clin Transl Immunology. 2021;10:e1323 pubmed 出版商
|
| Li L, Zhong J, Li M, Sun Y, Niu Y, Wu C, et al. Disruption of MAP7D1 Gene Function Increases the Risk of Doxorubicin-Induced Cardiomyopathy and Heart Failure. Biomed Res Int. 2021;2021:8569921 pubmed 出版商
|
| Bowles K, Silva M, Whitney K, Bertucci T, Berlind J, Lai J, et al. ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids. Cell. 2021;184:4547-4563.e17 pubmed 出版商
|
| Amaya C, Cameron C, Devarkar S, Seager S, Gerstein M, Xiong Y, et al. Nodal modulator (NOMO) is required to sustain endoplasmic reticulum morphology. J Biol Chem. 2021;297:100937 pubmed 出版商
|
| Cachón González M, Wang S, Cox T. Expression of Ripk1 and DAM genes correlates with severity and progression of Krabbe disease. Hum Mol Genet. 2021;30:2082-2099 pubmed 出版商
|
| Khan A, Johnson R, Wittmer C, Maile M, Tatsukawa K, Wong J, et al. NPT520-34 improves neuropathology and motor deficits in a transgenic mouse model of Parkinson's disease. Brain. 2021;: pubmed 出版商
|
| Kang H, Sarsenova M, Kim D, Kim M, Lee J, Sung E, et al. Establishing a 3D In Vitro Hepatic Model Mimicking Physiologically Relevant to In Vivo State. Cells. 2021;10: pubmed 出版商
|
| Sayed W, Elzainy A. Impact of platelet-rich plasma versus selenium in ameliorating induced toxicity in rat testis: histological, immunohistochemical, and molecular study. Cell Tissue Res. 2021;385:223-238 pubmed 出版商
|
| Kim J, Kim S, Kang H, Lee S, Park S, Cho Y, et al. TFEB-GDF15 axis protects against obesity and insulin resistance as a lysosomal stress response. Nat Metab. 2021;3:410-427 pubmed 出版商
|
| Huang Y, Liu H, Yuan Y, Guo Y, Wan D, Pan S. Exercise Preconditioning Increases Beclin1 and Induces Autophagy to Promote Early Myocardial Protection via Intermittent Myocardial Ischemia-Hypoxia. Int Heart J. 2021;62:407-415 pubmed 出版商
|
| Manganelli V, Capozzi A, Recalchi S, Riitano G, Mattei V, Longo A, et al. The Role of Cardiolipin as a Scaffold Mitochondrial Phospholipid in Autophagosome Formation: In Vitro Evidence. Biomolecules. 2021;11: pubmed 出版商
|
| Ordög K, Horvath O, Eros K, Bruszt K, Tóth S, Kovacs D, et al. Mitochondrial protective effects of PARP-inhibition in hypertension-induced myocardial remodeling and in stressed cardiomyocytes. Life Sci. 2021;268:118936 pubmed 出版商
|
| Zhuang L, Ly R, Rösl F, Niebler M. p53 Is Regulated in a Biphasic Manner in Hypoxic Human Papillomavirus Type 16 (HPV16)-Positive Cervical Cancer Cells. Int J Mol Sci. 2020;21: pubmed 出版商
|
| Pargianas M, Kosmas I, Papageorgiou K, Kitsou C, Papoudou Bai A, Batistatou A, et al. Follicle inhibition at the primordial stage without increasing apoptosis, with a combination of everolimus, verapamil. Mol Biol Rep. 2020;47:8711-8726 pubmed 出版商
|
| Moon Y, Kim I, Chang S, Park B, Lee S, Yoo S, et al. Hypoxia regulates allele-specific histone modification of the imprinted H19 gene. Biochim Biophys Acta Gene Regul Mech. 2020;1863:194643 pubmed 出版商
|
| Manganelli V, Matarrese P, Antonioli M, Gambardella L, Vescovo T, Gretzmeier C, et al. Raft-like lipid microdomains drive autophagy initiation via AMBRA1-ERLIN1 molecular association within MAMs. Autophagy. 2020;:1-21 pubmed 出版商
|
| Leist S, Dinnon K, Schäfer A, Tse L, Okuda K, Hou Y, et al. A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice. Cell. 2020;183:1070-1085.e12 pubmed 出版商
|
| Fucci C, Resnati M, Riva E, Perini T, Ruggieri E, Orfanelli U, et al. The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis. Cell Rep. 2020;32:108162 pubmed 出版商
|
| Dong W, Luo Y, Zhang G, Zhang H, Liang Y, Zhuo Y, et al. Carbon Nanospheres Exert Antitumor Effects Associated with Downregulation of 4E-BP1 Expression on Prostate Cancer. Int J Nanomedicine. 2020;15:5545-5559 pubmed 出版商
|
| Nettesheim A, Dixon A, Shim M, Coyne A, Walsh M, Liton P. Autophagy in the Aging and Experimental Ocular Hypertensive Mouse Model. Invest Ophthalmol Vis Sci. 2020;61:31 pubmed 出版商
|
| Di Pardo A, Pepe G, Capocci L, Marracino F, Amico E, Del Vecchio L, et al. Treatment with K6PC-5, a selective stimulator of SPHK1, ameliorates intestinal homeostasis in an animal model of Huntington's disease. Neurobiol Dis. 2020;143:105009 pubmed 出版商
|
| Zhang R, Varela M, Forn Cuni G, Torraca V, van der Vaart M, Meijer A. Deficiency in the autophagy modulator Dram1 exacerbates pyroptotic cell death of Mycobacteria-infected macrophages. Cell Death Dis. 2020;11:277 pubmed 出版商
|
| Fedele A, Proud C. Chloroquine and bafilomycin A mimic lysosomal storage disorders and impair mTORC1 signalling. Biosci Rep. 2020;40: pubmed 出版商
|
| Li W, Dai Y, Shi B, Yue F, Zou J, Xu G, et al. LRPPRC sustains Yap-P27-mediated cell ploidy and P62-HDAC6-mediated autophagy maturation and suppresses genome instability and hepatocellular carcinomas. Oncogene. 2020;39:3879-3892 pubmed 出版商
|
| Szekerczés T, Gógl A, Illyes I, Mandl J, Borka K, Kiss A, et al. Autophagy, Mitophagy and MicroRNA Expression in Chronic Hepatitis C and Autoimmune Hepatitis. Pathol Oncol Res. 2020;: pubmed 出版商
|
| Yuan J, Yuan Y, Pan S, Cai K. Altered expression levels of autophagy-associated proteins during exercise preconditioning indicate the involvement of autophagy in cardioprotection against exercise-induced myocardial injury. J Physiol Sci. 2020;70:10 pubmed 出版商
|
| Pomilio C, Gorojod R, Riudavets M, Vinuesa A, Presa J, Gregosa A, et al. Microglial autophagy is impaired by prolonged exposure to β-amyloid peptides: evidence from experimental models and Alzheimer's disease patients. GeroScience. 2020;42:613-632 pubmed 出版商
|
| Lindahl M, CHALAZONITIS A, Palm E, Pakarinen E, Danilova T, Pham T, et al. Cerebral dopamine neurotrophic factor-deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice. Neurobiol Dis. 2020;134:104696 pubmed 出版商
|
| Sarnyai F, Szekerczés T, Csala M, Sumegi B, Szarka A, Schaff Z, et al. BGP-15 Protects Mitochondria in Acute, Acetaminophen Overdose Induced Liver Injury. Pathol Oncol Res. 2020;26:1797-1803 pubmed 出版商
|
| Bryant J, Batis N, Franke A, Clancey G, Hartley M, Ryan G, et al. Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma. Oncotarget. 2019;10:5229-5244 pubmed 出版商
|
| Ding Y, Dvornikov A, Ma X, Zhang H, Wang Y, Lowerison M, et al. Haploinsufficiency of mechanistic target of rapamycin ameliorates bag3 cardiomyopathy in adult zebrafish. Dis Model Mech. 2019;12: pubmed 出版商
|
| Yong T, Zhang X, Bie N, Zhang H, Zhang X, Li F, et al. Tumor exosome-based nanoparticles are efficient drug carriers for chemotherapy. Nat Commun. 2019;10:3838 pubmed 出版商
|
| Gregosa A, Vinuesa A, Todero M, Pomilio C, Rossi S, Bentivegna M, et al. Periodic dietary restriction ameliorates amyloid pathology and cognitive impairment in PDAPP-J20 mice: Potential implication of glial autophagy. Neurobiol Dis. 2019;:104542 pubmed 出版商
|
| Liou Y, Chen P, Chu S, Kao S, Chang Y, Hsieh Y, et al. Thymoquinone suppresses the proliferation of renal cell carcinoma cells via reactive oxygen species-induced apoptosis and reduces cell stemness. Environ Toxicol. 2019;34:1208-1220 pubmed 出版商
|
| Di Pardo A, Pepe G, Castaldo S, Marracino F, Capocci L, Amico E, et al. Stimulation of Sphingosine Kinase 1 (SPHK1) Is Beneficial in a Huntington's Disease Pre-clinical Model. Front Mol Neurosci. 2019;12:100 pubmed 出版商
|
| Morelli M, Amantini C, Tomassoni D, Nabissi M, Arcella A, Santoni G. Transient Receptor Potential Mucolipin-1 Channels in Glioblastoma: Role in Patient's Survival. Cancers (Basel). 2019;11: pubmed 出版商
|
| Zhang R, Varela M, Vallentgoed W, Forn Cuni G, van der Vaart M, Meijer A. The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection. PLoS Pathog. 2019;15:e1007329 pubmed 出版商
|
| Hoffmann A, Minakaki G, Menges S, Salvi R, Savitskiy S, Kazman A, et al. Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose. Sci Rep. 2019;9:544 pubmed 出版商
|
| Minakaki G, Canneva F, Chevessier F, Bode F, Menges S, Timotius I, et al. Treadmill exercise intervention improves gait and postural control in alpha-synuclein mouse models without inducing cerebral autophagy. Behav Brain Res. 2019;363:199-215 pubmed 出版商
|
| Hollins S, Brock L, Barreto R, Harms L, Dunn A, Garcia Sobrinho P, et al. A Rodent Model of Anxiety: The Effect of Perinatal Immune Challenges on Gastrointestinal Inflammation and Integrity. Neuroimmunomodulation. 2018;25:163-175 pubmed 出版商
|
| Hanemaaijer E, Panahi M, Swaddiwudhipong N, Tikka S, Winblad B, Viitanen M, et al. Autophagy-lysosomal defect in human CADASIL vascular smooth muscle cells. Eur J Cell Biol. 2018;97:557-567 pubmed 出版商
|
| Ozturk D, Kocak M, Akcay A, Kınoglu K, Kara E, Buyuk Y, et al. MITF-MIR211 axis is a novel autophagy amplifier system during cellular stress. Autophagy. 2018;:1-16 pubmed 出版商
|
| Hirt J, Porter K, Dixon A, McKinnon S, Liton P. Contribution of autophagy to ocular hypertension and neurodegeneration in the DBA/2J spontaneous glaucoma mouse model. Cell Death Discov. 2018;4:14 pubmed 出版商
|
| Schäffner I, Minakaki G, Khan M, Balta E, Schlötzer Schrehardt U, Schwarz T, et al. FoxO Function Is Essential for Maintenance of Autophagic Flux and Neuronal Morphogenesis in Adult Neurogenesis. Neuron. 2018;99:1188-1203.e6 pubmed 出版商
|
| Maier L, Kallenberger S, Jechow K, Waschow M, Eils R, Conrad C. Unraveling mitotic protein networks by 3D multiplexed epitope drug screening. Mol Syst Biol. 2018;14:e8238 pubmed 出版商
|
| Battista R, Resnati M, Facchi C, Ruggieri E, Cremasco F, Paradiso F, et al. Autophagy mediates epithelial cancer chemoresistance by reducing p62/SQSTM1 accumulation. PLoS ONE. 2018;13:e0201621 pubmed 出版商
|
| Kustermann M, Manta L, Paone C, Kustermann J, Lausser L, Wiesner C, et al. Loss of the novel Vcp (valosin containing protein) interactor Washc4 interferes with autophagy-mediated proteostasis in striated muscle and leads to myopathy in vivo. Autophagy. 2018;14:1911-1927 pubmed 出版商
|
| Lu J, Dong W, He H, Han Z, Zhuo Y, Mo R, et al. Autophagy induced by overexpression of DCTPP1 promotes tumor progression and predicts poor clinical outcome in prostate cancer. Int J Biol Macromol. 2018;118:599-609 pubmed 出版商
|
| Saera Vila A, Kish P, Kahana A. Autophagy in Zebrafish Extraocular Muscle Regeneration. Methods Mol Biol. 2019;1854:105-117 pubmed 出版商
|
| Chmielewska M, Dedukh D, Haczkiewicz K, Rozenblut Kościsty B, Kaźmierczak M, Kolenda K, et al. The programmed DNA elimination and formation of micronuclei in germ line cells of the natural hybridogenetic water frog Pelophylax esculentus. Sci Rep. 2018;8:7870 pubmed 出版商
|
| Lim H, Lim Y, Kim K, Jeon Y, Park K, Kim J, et al. A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes. Nat Commun. 2018;9:1438 pubmed 出版商
|
| Pernas L, Bean C, Boothroyd J, Scorrano L. Mitochondria Restrict Growth of the Intracellular Parasite Toxoplasma gondii by Limiting Its Uptake of Fatty Acids. Cell Metab. 2018;27:886-897.e4 pubmed 出版商
|
| Anunobi R, Boone B, Cheh N, Tang D, Kang R, Loux T, et al. Extracellular DNA promotes colorectal tumor cell survival after cytotoxic chemotherapy. J Surg Res. 2018;226:181-191 pubmed 出版商
|
| Fusco C, Mandriani B, Di Rienzo M, Micale L, Malerba N, Cocciadiferro D, et al. TRIM50 regulates Beclin 1 proautophagic activity. Biochim Biophys Acta Mol Cell Res. 2018;1865:908-919 pubmed 出版商
|
| Jeong A, Ka H, Han S, Lee S, Lee E, Soh S, et al. Oncoprotein CIP2A promotes the disassembly of primary cilia and inhibits glycolytic metabolism. EMBO Rep. 2018;19: pubmed 出版商
|
| Piacentini M, Baiocchini A, Del Nonno F, Melino G, Barlev N, Rossin F, et al. Non-alcoholic fatty liver disease severity is modulated by transglutaminase type 2. Cell Death Dis. 2018;9:257 pubmed 出版商
|
| Inomata Y, Nagasaka S, Miyate K, Goto Y, Hino C, Toukairin C, et al. Bcl-2-associated athanogene 3 (BAG3) is an enhancer of small heat shock protein turnover via activation of autophagy in the heart. Biochem Biophys Res Commun. 2018;496:1141-1147 pubmed 出版商
|
| Festa B, Chen Z, Berquez M, Debaix H, Tokonami N, Prange J, et al. Impaired autophagy bridges lysosomal storage disease and epithelial dysfunction in the kidney. Nat Commun. 2018;9:161 pubmed 出版商
|
| Nager M, Sallán M, Visa A, Pushparaj C, Santacana M, Macià A, et al. Inhibition of WNT-CTNNB1 signaling upregulates SQSTM1 and sensitizes glioblastoma cells to autophagy blockers. Autophagy. 2018;14:619-636 pubmed 出版商
|
| Palucci I, Matic I, Falasca L, Minerva M, Maulucci G, De Spirito M, et al. Transglutaminase type 2 plays a key role in the pathogenesis of Mycobacterium tuberculosis infection. J Intern Med. 2018;283:303-313 pubmed 出版商
|
| Minakaki G, Menges S, Kittel A, Emmanouilidou E, Schaeffner I, Barkovits K, et al. Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype. Autophagy. 2017;:1-61 pubmed 出版商
|
| Jiang M, Han Z, Li W, Yue F, Ye J, Li B, et al. Mitochondrion-associated protein peroxiredoxin 3 promotes benign prostatic hyperplasia through autophagy suppression and pyroptosis activation. Oncotarget. 2017;8:80295-80302 pubmed 出版商
|
| Desseille C, Deforges S, Biondi O, Houdebine L, D Amico D, Lamaziere A, et al. Specific Physical Exercise Improves Energetic Metabolism in the Skeletal Muscle of Amyotrophic-Lateral- Sclerosis Mice. Front Mol Neurosci. 2017;10:332 pubmed 出版商
|
| Theofilas P, Ehrenberg A, Nguy A, Thackrey J, Dunlop S, Mejia M, et al. Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans. Neurobiol Aging. 2018;61:1-12 pubmed 出版商
|
| Kaverina N, Borovjagin A, Kadagidze Z, Baryshnikov A, Baryshnikova M, Malin D, et al. Astrocytes promote progression of breast cancer metastases to the brain via a KISS1-mediated autophagy. Autophagy. 2017;13:1905-1923 pubmed 出版商
|
| Agarwal A, Tunison K, Dalal J, Nagamma S, Hamra F, Sankella S, et al. Metabolic, Reproductive, and Neurologic Abnormalities in Agpat1-Null Mice. Endocrinology. 2017;158:3954-3973 pubmed 出版商
|
| Solanas G, Peixoto F, Perdiguero E, Jardi M, Ruiz Bonilla V, Datta D, et al. Aged Stem Cells Reprogram Their Daily Rhythmic Functions to Adapt to Stress. Cell. 2017;170:678-692.e20 pubmed 出版商
|
| Benítez B, Sands M. Primary fibroblasts from CSPα mutation carriers recapitulate hallmarks of the adult onset neuronal ceroid lipofuscinosis. Sci Rep. 2017;7:6332 pubmed 出版商
|
| McLendon P, Davis G, Gulick J, Singh S, Xu N, Salomonis N, et al. An Unbiased High-Throughput Screen to Identify Novel Effectors That Impact on Cardiomyocyte Aggregate Levels. Circ Res. 2017;121:604-616 pubmed 出版商
|
| Nazim U, Moon J, Lee Y, Seol J, Park S. PPARγ activation by troglitazone enhances human lung cancer cells to TRAIL-induced apoptosis via autophagy flux. Oncotarget. 2017;8:26819-26831 pubmed 出版商
|
| Massimini M, Palmieri C, De Maria R, Romanucci M, Malatesta D, De Martinis M, et al. 17-AAG and Apoptosis, Autophagy, and Mitophagy in Canine Osteosarcoma Cell Lines. Vet Pathol. 2017;54:405-412 pubmed 出版商
|
| Fu Q, Chen K, Zhu Q, Wang W, Huang F, Miao L, et al. ?-catenin promotes intracellular bacterial killing via suppression of Pseudomonas aeruginosa-triggered macrophage autophagy. J Int Med Res. 2017;45:556-569 pubmed 出版商
|
| Bae S, Byun S, Bae S, Min D, Woo H, Lee K. TPT1 (tumor protein, translationally-controlled 1) negatively regulates autophagy through the BECN1 interactome and an MTORC1-mediated pathway. Autophagy. 2017;13:820-833 pubmed 出版商
|
| Yue F, Li W, Zou J, Jiang X, Xu G, Huang H, et al. Spermidine Prolongs Lifespan and Prevents Liver Fibrosis and Hepatocellular Carcinoma by Activating MAP1S-Mediated Autophagy. Cancer Res. 2017;77:2938-2951 pubmed 出版商
|
| Lopez A, Lee S, Wojta K, Ramos E, Klein E, Chen J, et al. A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction. Brain. 2017;140:1128-1146 pubmed 出版商
|
| Mattoscio D, Casadio C, Miccolo C, Maffini F, Raimondi A, Tacchetti C, et al. Autophagy regulates UBC9 levels during viral-mediated tumorigenesis. PLoS Pathog. 2017;13:e1006262 pubmed 出版商
|
| GarcÃa Prat L, Muñoz Cánoves P, MartÃnez Vicente M. Monitoring Autophagy in Muscle Stem Cells. Methods Mol Biol. 2017;1556:255-280 pubmed 出版商
|
| Schulze U, Vollenbröker B, Kühnl A, Granado D, Bayraktar S, Rescher U, et al. Cellular vacuolization caused by overexpression of the PIKfyve-binding deficient Vac14L156R is rescued by starvation and inhibition of vacuolar-ATPase. Biochim Biophys Acta Mol Cell Res. 2017;1864:749-759 pubmed 出版商
|
| Nuschke A, Rodrigues M, Wells A, Sylakowski K, Wells A. Mesenchymal stem cells/multipotent stromal cells (MSCs) are glycolytic and thus glucose is a limiting factor of in vitro models of MSC starvation. Stem Cell Res Ther. 2016;7:179 pubmed
|
| Lu Y, Liu X, Liu T, Fan R, Xu Y, Zhang X, et al. Celecoxib exerts antitumor effects in HL-60 acute leukemia cells and inhibits autophagy by affecting lysosome function. Biomed Pharmacother. 2016;84:1551-1557 pubmed 出版商
|
| Lee S, Kang J, Kim S, Ahn J, Kim J, Lee S. Afzelin ameliorates D-galactosamine and lipopolysaccharide-induced fulminant hepatic failure by modulating mitochondrial quality control and dynamics. Br J Pharmacol. 2017;174:195-209 pubmed 出版商
|
| Shingu T, Ho A, Yuan L, Zhou X, Dai C, Zheng S, et al. Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation. Nat Genet. 2017;49:75-86 pubmed 出版商
|
| Jiang C, Jin S, Jiang Z, Wang J. Inhibitory effects of silibinin on proliferation and lung metastasis of human high metastasis cell line of salivary gland adenoid cystic carcinoma via autophagy induction. Onco Targets Ther. 2016;9:6609-6618 pubmed
|
| Zhang D, Pan J, Xiang X, Liu Y, Dong G, Livingston M, et al. Protein Kinase Cδ Suppresses Autophagy to Induce Kidney Cell Apoptosis in Cisplatin Nephrotoxicity. J Am Soc Nephrol. 2017;28:1131-1144 pubmed 出版商
|
| Song X, Xie Y, Kang R, Hou W, Sun X, Epperly M, et al. FANCD2 protects against bone marrow injury from ferroptosis. Biochem Biophys Res Commun. 2016;480:443-449 pubmed 出版商
|
| Liu P, Jin H, Guo Z, Ma J, Zhao J, Li D, et al. Silver nanoparticles outperform gold nanoparticles in radiosensitizing U251 cells in vitro and in an intracranial mouse model of glioma. Int J Nanomedicine. 2016;11:5003-5014 pubmed
|
| Benvenuto M, Mattera R, Masuelli L, Taffera G, Andracchio O, Tresoldi I, et al. (±)-Gossypol induces apoptosis and autophagy in head and neck carcinoma cell lines and inhibits the growth of transplanted salivary gland cancer cells in BALB/c mice. Int J Food Sci Nutr. 2017;68:298-312 pubmed 出版商
|
| Morell C, Bort A, Vara Ciruelos D, Ramos Torres Á, Altamirano Dimas M, Díaz Laviada I, et al. Up-Regulated Expression of LAMP2 and Autophagy Activity during Neuroendocrine Differentiation of Prostate Cancer LNCaP Cells. PLoS ONE. 2016;11:e0162977 pubmed 出版商
|
| Yamada E, Okada S, Bastie C, Vatish M, Nakajima Y, Shibusawa R, et al. Fyn phosphorylates AMPK to inhibit AMPK activity and AMP-dependent activation of autophagy. Oncotarget. 2016;7:74612-74629 pubmed 出版商
|
| Mo Z, Li W, Zhai Y, Gong Q. Icariin Attenuates OGD/R-Induced Autophagy via Bcl-2-Dependent Cross Talk between Apoptosis and Autophagy in PC12 Cells. Evid Based Complement Alternat Med. 2016;2016:4343084 pubmed 出版商
|
| Caccamo A, Ferreira E, Branca C, Oddo S. p62 improves AD-like pathology by increasing autophagy. Mol Psychiatry. 2017;22:865-873 pubmed 出版商
|
| Saini N, Baena A, Ng T, Venkataswamy M, Kennedy S, Kunnath Velayudhan S, et al. Suppression of autophagy and antigen presentation by Mycobacterium tuberculosis PE_PGRS47. Nat Microbiol. 2016;1:16133 pubmed 出版商
|
| Tan K, Ho M, Cho H, Yu J, Hung J, Yu A. Fucosylation of LAMP-1 and LAMP-2 by FUT1 correlates with lysosomal positioning and autophagic flux of breast cancer cells. Cell Death Dis. 2016;7:e2347 pubmed 出版商
|
| Sun X, Sun L, Zhao Y, Li Y, Lin W, Chen D, et al. MAVS maintains mitochondrial homeostasis via autophagy. Cell Discov. 2016;2:16024 pubmed 出版商
|
| Sabha N, Volpatti J, Gonorazky H, Reifler A, Davidson A, Li X, et al. PIK3C2B inhibition improves function and prolongs survival in myotubular myopathy animal models. J Clin Invest. 2016;126:3613-25 pubmed 出版商
|
| Hong J, Kim S, Lee S. Role of necroptosis in autophagy signaling during hepatic ischemia and reperfusion. Toxicol Appl Pharmacol. 2016;308:1-10 pubmed 出版商
|
| Du J, Zhu W, Yang L, Wu C, Lin B, Wu J, et al. Reduction of polyethylenimine-coated iron oxide nanoparticles induced autophagy and cytotoxicity by lactosylation. Regen Biomater. 2016;3:223-9 pubmed 出版商
|
| Granato M, Zompetta C, Vescarelli E, Rizzello C, Cardi A, Valia S, et al. HCV derived from sera of HCV-infected patients induces pro-fibrotic effects in human primary fibroblasts by activating GLI2. Sci Rep. 2016;6:30649 pubmed 出版商
|
| Wu H, Wang J, Zhang B, Fang L, Xu K, Liu R. CpG-ODN promotes phagocytosis and autophagy through JNK/P38 signal pathway in Staphylococcus aureus-stimulated macrophage. Life Sci. 2016;161:51-9 pubmed 出版商
|
| Saera Vila A, Kish P, Louie K, Grzegorski S, Klionsky D, Kahana A. Autophagy regulates cytoplasmic remodeling during cell reprogramming in a zebrafish model of muscle regeneration. Autophagy. 2016;12:1864-1875 pubmed
|
| Suzuki K, Yamaguchi A, Yamanaka S, Kanzaki S, Kawashima M, Togo T, et al. Accumulated ?-synuclein affects the progression of GM2 gangliosidoses. Exp Neurol. 2016;284:38-49 pubmed 出版商
|
| Lee H, Kim J, Quan W, Lee J, Kim M, Kim S, et al. Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis. Autophagy. 2016;12:1390-403 pubmed 出版商
|
| Erbil S, Oral O, Mitou G, Kig C, Durmaz Timucin E, Guven Maiorov E, et al. RACK1 Is an Interaction Partner of ATG5 and a Novel Regulator of Autophagy. J Biol Chem. 2016;291:16753-65 pubmed 出版商
|
| Pema M, Drusian L, Chiaravalli M, Castelli M, Yao Q, Ricciardi S, et al. mTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex. Nat Commun. 2016;7:10786 pubmed 出版商
|
| Altuntas S, Rossin F, Marsella C, D Eletto M, Diaz Hidalgo L, Farrace M, et al. The transglutaminase type 2 and pyruvate kinase isoenzyme M2 interplay in autophagy regulation. Oncotarget. 2015;6:44941-54 pubmed 出版商
|
| Duarte Silva S, Silva Fernandes A, Neves Carvalho A, Soares Cunha C, Teixeira Castro A, Maciel P. Combined therapy with m-TOR-dependent and -independent autophagy inducers causes neurotoxicity in a mouse model of Machado-Joseph disease. Neuroscience. 2016;313:162-73 pubmed 出版商
|
| Song K, Hu W, Yue F, Zou J, Li W, Chen Q, et al. Transforming Growth Factor TGFβ Increases Levels of Microtubule-Associated Protein MAP1S and Autophagy Flux in Pancreatic Ductal Adenocarcinomas. PLoS ONE. 2015;10:e0143150 pubmed 出版商
|
| Muhammad E, Levitas A, Singh S, Braiman A, Ofir R, Etzion S, et al. PLEKHM2 mutation leads to abnormal localization of lysosomes, impaired autophagy flux and associates with recessive dilated cardiomyopathy and left ventricular noncompaction. Hum Mol Genet. 2015;24:7227-40 pubmed 出版商
|
| Xiong R, Zhou W, Siegel D, Kitson R, Freed C, Moody C, et al. A Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T α-Synuclein Toxicity. Mol Pharmacol. 2015;88:1045-54 pubmed 出版商
|
| Grossi V, Lucarelli G, Forte G, Peserico A, Matrone A, Germani A, et al. Loss of STK11 expression is an early event in prostate carcinogenesis and predicts therapeutic response to targeted therapy against MAPK/p38. Autophagy. 2015;11:2102-2113 pubmed 出版商
|
| Lapash Daniels C, Paffenroth E, Austin E, Glebov K, Lewis D, Walter J, et al. Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease. PLoS ONE. 2015;10:e0138132 pubmed 出版商
|
| Chen Q, Yue F, Li W, Zou J, Xu T, Huang C, et al. Potassium Bisperoxo(1,10-phenanthroline)oxovanadate (bpV(phen)) Induces Apoptosis and Pyroptosis and Disrupts the P62-HDAC6 Protein Interaction to Suppress the Acetylated Microtubule-dependent Degradation of Autophagosomes. J Biol Chem. 2015;290:26051-8 pubmed 出版商
|
| Zhen Y, Li W. Impairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33A(D251E) mutation. Autophagy. 2015;11:1608-22 pubmed 出版商
|
| Pomilio C, Pavía P, Gorojod R, Vinuesa A, Alaimo A, Galvan V, et al. Glial alterations from early to late stages in a model of Alzheimer's disease: Evidence of autophagy involvement in A? internalization. Hippocampus. 2016;26:194-210 pubmed 出版商
|
| Irimia J, Tagliabracci V, Meyer C, Segvich D, DePaoli Roach A, Roach P. Muscle glycogen remodeling and glycogen phosphate metabolism following exhaustive exercise of wild type and laforin knockout mice. J Biol Chem. 2015;290:22686-98 pubmed 出版商
|
| Kabak Y, Sozmen M, Yarim M, Guvenc T, Karayigit M, Gulbahar M. Immunohistochemical detection of autophagy-related microtubule-associated protein 1 light chain 3 (LC3) in the cerebellums of dogs naturally infected with canine distemper virus. Biotech Histochem. 2015;90:601-7 pubmed 出版商
|
| Gorojod R, Alaimo A, Porte Alcon S, Pomilio C, Saravia F, Kotler M. The autophagic- lysosomal pathway determines the fate of glial cells under manganese- induced oxidative stress conditions. Free Radic Biol Med. 2015;87:237-51 pubmed 出版商
|
| Lin C, Jan M, Kuo J. Exploring MicroRNA Expression Profiles Related to the mTOR Signaling Pathway in Mouse Embryonic Fibroblast Cells Treated with Polyethylenimine. Mol Pharm. 2015;12:2858-68 pubmed 出版商
|
| Nabissi M, Morelli M, Amantini C, Liberati S, Santoni M, Ricci Vitiani L, et al. Cannabidiol stimulates Aml-1a-dependent glial differentiation and inhibits glioma stem-like cells proliferation by inducing autophagy in a TRPV2-dependent manner. Int J Cancer. 2015;137:1855-69 pubmed 出版商
|
| Wang T, Martin S, Papadopulos A, Harper C, Mavlyutov T, Niranjan D, et al. Control of autophagosome axonal retrograde flux by presynaptic activity unveiled using botulinum neurotoxin type a. J Neurosci. 2015;35:6179-94 pubmed 出版商
|
| Ulasov I, Shah N, Kaverina N, Lee H, Lin B, Lieber A, et al. Tamoxifen improves cytopathic effect of oncolytic adenovirus in primary glioblastoma cells mediated through autophagy. Oncotarget. 2015;6:3977-87 pubmed
|
| Wei Y, An Z, Zou Z, Sumpter R, Su M, Zang X, et al. The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation. elife. 2015;4: pubmed 出版商
|
| Zou J, Li W, Misra A, Yue F, Song K, Chen Q, et al. The viral restriction factor tetherin prevents leucine-rich pentatricopeptide repeat-containing protein (LRPPRC) from association with beclin 1 and B-cell CLL/lymphoma 2 (Bcl-2) and enhances autophagy and mitophagy. J Biol Chem. 2015;290:7269-79 pubmed 出版商
|
| Wilson W, Baumgarner B, Watanabe W, Alam M, Kinsey S. Effects of resveratrol on growth and skeletal muscle physiology of juvenile southern flounder. Comp Biochem Physiol A Mol Integr Physiol. 2015;183:27-35 pubmed 出版商
|
| Varga M, Fodor E, Vellai T. Autophagy in zebrafish. Methods. 2015;75:172-80 pubmed 出版商
|
| Gan M, Moussaud S, Jiang P, McLean P. Extracellular ATP induces intracellular alpha-synuclein accumulation via P2X1 receptor-mediated lysosomal dysfunction. Neurobiol Aging. 2015;36:1209-20 pubmed 出版商
|
| Carlisi D, Lauricella M, D Anneo A, Buttitta G, Emanuele S, Di Fiore R, et al. The synergistic effect of SAHA and parthenolide in MDA-MB231 breast cancer cells. J Cell Physiol. 2015;230:1276-89 pubmed 出版商
|
| Cai McRae X, Zhong H, Karantza V. Sequestosome 1/p62 facilitates HER2-induced mammary tumorigenesis through multiple signaling pathways. Oncogene. 2015;34:2968-77 pubmed 出版商
|
| Zhang L, Chen X, Sharma P, Moon M, Sheftel A, Dawood F, et al. HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress. Nat Commun. 2014;5:3430 pubmed 出版商
|
| Clarke A, Ellinghaus U, Cortini A, Stranks A, Simon A, Botto M, et al. Autophagy is activated in systemic lupus erythematosus and required for plasmablast development. Ann Rheum Dis. 2015;74:912-20 pubmed 出版商
|