产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
DNMT1抗体
目录 :
NB100-264
规格 :
0.1毫升
价格 :
333美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
5B10
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 10
参考文献
Liu N, Zhang X, Jiang S, Shi J, Cui J, Liu X, et al. Neuroprotective mechanisms of DNA methyltransferase in a mouse hippocampal neuronal cell line after hypoxic preconditioning. Neural Regen Res. 2020;15:2362-2368 pubmed 出版商
Raja G, Lite C, Subhashree K, Santosh W, Barathi S. Prenatal bisphenol-A exposure altered exploratory and anxiety-like behaviour and induced non-monotonic, sex-specific changes in the cortical expression of CYP19A1, BDNF and intracellular signaling proteins in F1 rats. Food Chem Toxicol. 2020;142:111442 pubmed 出版商
Chen Z, Zheng J, Hong H, Chen D, Deng L, Zhang X, et al. lncRNA HOTAIRM1 promotes osteogenesis of hDFSCs by epigenetically regulating HOXA2 via DNMT1 in vitro. J Cell Physiol. 2020;: pubmed 出版商
Liberti D, Zepp J, Bartoni C, Liberti K, Zhou S, Lu M, et al. Dnmt1 is required for proximal-distal patterning of the lung endoderm and for restraining alveolar type 2 cell fate. Dev Biol. 2019;454:108-117 pubmed 出版商
Sikorski K, Mehta A, Inngjerdingen M, Thakor F, Kling S, Kalina T, et al. A high-throughput pipeline for validation of antibodies. Nat Methods. 2018;15:909-912 pubmed 出版商
Gustafsson J, Katsioudi G, Degn M, Ejlerskov P, Issazadeh Navikas S, Kornum B. DNMT1 regulates expression of MHC class I in post-mitotic neurons. Mol Brain. 2018;11:36 pubmed 出版商
Gu H, Gao J, Guo W, Zhou Y, Kong Q. The expression of DNA methyltransferases3A is specifically downregulated in chorionic villi of early embryo growth arrest cases. Mol Med Rep. 2017;16:591-596 pubmed 出版商
Chang C, Pirozzi G, Wen S, Chung I, Chiu B, Errico S, et al. Multiple structural and epigenetic defects in the human leukocyte antigen class I antigen presentation pathway in a recurrent metastatic melanoma following immunotherapy. J Biol Chem. 2015;290:26562-75 pubmed 出版商
Vispé S, Deroide A, Davoine E, Desjobert C, Lestienne F, Fournier L, et al. Consequences of combining siRNA-mediated DNA methyltransferase 1 depletion with 5-aza-2'-deoxycytidine in human leukemic KG1 cells. Oncotarget. 2015;6:15265-82 pubmed
Cui Y, Irudayaraj J. Dissecting the behavior and function of MBD3 in DNA methylation homeostasis by single-molecule spectroscopy and microscopy. Nucleic Acids Res. 2015;43:3046-55 pubmed 出版商
图像
图像 1 :
Novus Biologicals NB100-264 图像 1
Knockout Validated: DNMT1 Antibody [NB100-264] - Lysates of HEK293 human embryonic kidney parental cell line and DNMT1 knockout (KO) HEK293 cell line. PVDF membrane was probed with 1:100 of Rabbit Anti-Human DNMT1 Polyclonal Antibody (Catalog # NB100-264) followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog #HAF008). Specific band was detected for DNMT1 at approximately 240 kDa (as indicated) in the parental HEK293 cell line, but is not detectable in the knockout HEK293 cell line. This experiment was conducted under reducing conditions.
产品信息
品牌 :
Novus
SKU号 :
NB100-264
产品名称 :
DNMT1抗体
单位尺寸 :
0.1毫升
描述 :
The DNMT1 Antibody from Novus is a rabbit polyclonal antibody to DNMT1. This antibody reacts with human, mouse. The DNMT1 Antibody has been validated for the following applications: Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Knockout Validated, Knockdown Validated.
靶标 :
DNMT1
类别 :
一抗
缓冲液 :
Whole antisera
克隆性 :
多克隆
共轭标签 :
未共轭
宿主 :
免疫原 :
Contained within amino acids 1-125 of the N-terminus of human Dnmt1. [UniProt# P26358]
抗体亚型 :
IgG
纯度 :
Unpurified
物种 :
人类, 小鼠
储存 :
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
用途 :
In Western blot a band can be seen at ~190 kDa. NOTE: This antibody does not neutralize the enzymatic activity of its corresponding methyltransferase. In Simple Western only 10 - 15 uL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue.
理论上的分子量 :
190 kDa
基因符号 :
DNMT1
catalog number base :
NB100-264
accessionNumbers :
P26358
应用 :
Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Knockout Validated, Knockdown Validated
美元 :
333美元
default size :
TRUE
别名 :
AIM, CXXC9CXXC finger protein 9, CXXC-type zinc finger protein 9, DNA (cytosine-5-)-methyltransferase 1, DNA (cytosine-5)-methyltransferase 1, DNA methyltransferase 1, DNA methyltransferase HsaI, DNA MTase HsaI, DNMT, Dnmt1, EC 2.1.1.37, FLJ16293, m.HsaI, MCMTMGC104992
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。