产品简要
公司名称 :
Novus Biologicals
其他品牌 :
IMGENEX
产品类型 :
抗体
产品名称 :
53BP1抗体
目录 :
NB100-304
规格 :
0.025毫升
价格 :
149美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
仓鼠, 人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 272
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 图 2c
Wang H, Nakamura M, Abbott T, Zhao D, Luo K, Yu C, et al. CRISPR-mediated live imaging of genome editing and transcription. Science. 2019;: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 7c
Wen H, Gao S, Wang Y, Ray M, Magnuson M, Wright C, et al. Myeloid cell-derived HB-EGF Drives Tissue Recovery After Pancreatitis. Cell Mol Gastroenterol Hepatol. 2019;: pubmed 出版商
  • 免疫细胞化学; 人类; 图 s10a
Zhang M, Wang B, Li T, Liu R, Xiao Y, Geng X, et al. Mammalian CST averts replication failure by preventing G-quadruplex accumulation. Nucleic Acids Res. 2019;47:5243-5259 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:5000; 图 s2d
López Erauskin J, Tadokoro T, Baughn M, Myers B, McAlonis Downes M, Chillon Marinas C, et al. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS. Neuron. 2018;100:816-830.e7 pubmed 出版商
  • 免疫细胞化学; 人类; 1:250; 图 s5d
Schrank B, Aparicio T, Li Y, Chang W, Chait B, Gundersen G, et al. Nuclear ARP2/3 drives DNA break clustering for homology-directed repair. Nature. 2018;559:61-66 pubmed 出版商
  • 免疫细胞化学; 人类; 图 6
Cottineau J, Kottemann M, Lach F, Kang Y, Vély F, Deenick E, et al. Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency. J Clin Invest. 2017;127:1991-2006 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2b
Vancevska A, Douglass K, Pfeiffer V, Manley S, Lingner J. The telomeric DNA damage response occurs in the absence of chromatin decompaction. Genes Dev. 2017;31:567-577 pubmed 出版商
  • 免疫印迹; 人类; 图 4d
Liu Y, Cussiol J, Dibitetto D, Sims J, Twayana S, Weiss R, et al. TOPBP1Dpb11 plays a conserved role in homologous recombination DNA repair through the coordinated recruitment of 53BP1Rad9. J Cell Biol. 2017;216:623-639 pubmed 出版商
  • 免疫细胞化学; 人类
Li J, Miralles Fusté J, Simavorian T, Bartocci C, Tsai J, Karlseder J, et al. TZAP: A telomere-associated protein involved in telomere length control. Science. 2017;355:638-641 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3d
Mytych J, Wos I, Solek P, Koziorowski M. Protective role of klotho protein on epithelial cells upon co-culture with activated or senescent monocytes. Exp Cell Res. 2017;350:358-367 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 2a
Tumini E, Barroso S, Calero C, Aguilera A. Roles of human POLD1 and POLD3 in genome stability. Sci Rep. 2016;6:38873 pubmed 出版商
  • 免疫组化; 小鼠; 图 2c
Bezine E, Malaisé Y, Loeuillet A, Chevalier M, Boutet Robinet E, Salles B, et al. Cell resistance to the Cytolethal Distending Toxin involves an association of DNA repair mechanisms. Sci Rep. 2016;6:36022 pubmed 出版商
  • 免疫细胞化学; 大鼠; 1:500; 图 4c
Piechota M, Sunderland P, Wysocka A, Nalberczak M, Sliwinska M, Radwanska K, et al. Is senescence-associated β-galactosidase a marker of neuronal senescence?. Oncotarget. 2016;7:81099-81109 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:600; 图 2
Lescale C, Lenden Hasse H, Blackford A, Balmus G, Bianchi J, Yu W, et al. Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination. Cell Rep. 2016;16:2967-2979 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s2d
Schmidt J, Zaug A, Cech T. Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres. Cell. 2016;166:1188-1197.e9 pubmed 出版商
  • 免疫细胞化学; 人类; 1:2000; 图 1
Mao P, Liu J, Zhang Z, Zhang H, Liu H, Gao S, et al. Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells. Nat Commun. 2016;7:12154 pubmed 出版商
  • 免疫细胞化学; 人类; 1:3000; 图 5
Jullien D, Vignard J, Fedor Y, Bery N, Olichon A, Crozatier M, et al. Chromatibody, a novel non-invasive molecular tool to explore and manipulate chromatin in living cells. J Cell Sci. 2016;129:2673-83 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 2
Ho T, Guilbaud G, Blow J, Sale J, Watson C. The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability. Cell Rep. 2016;15:724-734 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4
  • 免疫印迹; 人类; 图 4
Chiang T, le Sage C, Larrieu D, Demir M, Jackson S. CRISPR-Cas9(D10A) nickase-based genotypic and phenotypic screening to enhance genome editing. Sci Rep. 2016;6:24356 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3a
Medves S, Auchter M, Chambeau L, Gazzo S, Poncet D, Grangier B, et al. A high rate of telomeric sister chromatid exchange occurs in chronic lymphocytic leukaemia B-cells. Br J Haematol. 2016;174:57-70 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1d
O Hagan Wong K, Nadeau S, Carrier Leclerc A, Apablaza F, Hamdy R, Shum Tim D, et al. Increased IL-6 secretion by aged human mesenchymal stromal cells disrupts hematopoietic stem and progenitor cells' homeostasis. Oncotarget. 2016;7:13285-96 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 2
  • 免疫印迹; 人类; 图 s3
Francia S, Cabrini M, Matti V, Oldani A, d Adda di Fagagna F. DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors. J Cell Sci. 2016;129:1468-76 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Cekan P, Hasegawa K, Pan Y, Tubman E, Odde D, Chen J, et al. RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence. Mol Biol Cell. 2016;27:1346-57 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s7
Nagy Z, Kalousi A, Furst A, Koch M, Fischer B, Soutoglou E. Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs. PLoS Genet. 2016;12:e1005791 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4
Zhang H, Liu H, Chen Y, Yang X, Wang P, Liu T, et al. A cell cycle-dependent BRCA1-UHRF1 cascade regulates DNA double-strand break repair pathway choice. Nat Commun. 2016;7:10201 pubmed 出版商
  • 免疫细胞化学; 仓鼠; 1:1000; 图 8
Chatalic K, Konijnenberg M, Nonnekens J, De Blois E, Hoeben S, de Ridder C, et al. In Vivo Stabilization of a Gastrin-Releasing Peptide Receptor Antagonist Enhances PET Imaging and Radionuclide Therapy of Prostate Cancer in Preclinical Studies. Theranostics. 2016;6:104-17 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Obermeier K, Sachsenweger J, Friedl T, Pospiech H, Winqvist R, Wiesmüller L. Heterozygous PALB2 c.1592delT mutation channels DNA double-strand break repair into error-prone pathways in breast cancer patients. Oncogene. 2016;35:3796-806 pubmed 出版商
  • 免疫细胞化学; 人类; 1:2000; 图 5a
Kubben N, Brimacombe K, Donegan M, Li Z, Misteli T. A high-content imaging-based screening pipeline for the systematic identification of anti-progeroid compounds. Methods. 2016;96:46-58 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 6c
Petroni M, Sardina F, Heil C, Sahún Roncero M, Colicchia V, Veschi V, et al. The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress. Cell Death Differ. 2016;23:197-206 pubmed 出版商
Hu Z, Mi S, Zhao T, Peng C, Peng Y, Chen L, et al. BGL3 lncRNA mediates retention of the BRCA1/BARD1 complex at DNA damage sites. EMBO J. 2020;39:e104133 pubmed 出版商
Schochter F, Werner K, Köstler C, Faul A, Tzschaschel M, Alberter B, et al. 53BP1 Accumulation in Circulating Tumor Cells Identifies Chemotherapy-Responsive Metastatic Breast Cancer Patients. Cancers (Basel). 2020;12: pubmed 出版商
Gzil A, Jaworski D, Antosik P, Zarębska I, Durślewicz J, Dominiak J, et al. The impact of TP53BP1 and MLH1 on metastatic capability in cases of locally advanced prostate cancer and their usefulness in clinical practice. Urol Oncol. 2020;38:600.e17-600.e26 pubmed 出版商
Ramadan R, Vromans E, Anang D, Goetschalckx I, Hoorelbeke D, Decrock E, et al. Connexin43 Hemichannel Targeting With TAT-Gap19 Alleviates Radiation-Induced Endothelial Cell Damage. Front Pharmacol. 2020;11:212 pubmed 出版商
Ferrara Romeo I, Martinez P, Saraswati S, Whittemore K, Graña Castro O, Thelma Poluha L, et al. The mTOR pathway is necessary for survival of mice with short telomeres. Nat Commun. 2020;11:1168 pubmed 出版商
Salvador Barbero B, Alvarez Fernandez M, Zapatero Solana E, El Bakkali A, Menéndez M, López Casas P, et al. CDK4/6 Inhibitors Impair Recovery from Cytotoxic Chemotherapy in Pancreatic Adenocarcinoma. Cancer Cell. 2020;37:340-353.e6 pubmed 出版商
Gauthier T, Duarte Hospital C, Vignard J, Boutet Robinet E, Sulyok M, Snini S, et al. Versicolorin A, a precursor in aflatoxins biosynthesis, is a food contaminant toxic for human intestinal cells. Environ Int. 2020;137:105568 pubmed 出版商
Chojnowski A, Ong P, Foo M, Liebl D, Hor L, Stewart C, et al. Heterochromatin loss as a determinant of progerin-induced DNA damage in Hutchinson-Gilford Progeria. Aging Cell. 2020;19:e13108 pubmed 出版商
Struve N, Binder Z, Stead L, Brend T, Bagley S, Faulkner C, et al. EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma. Oncogene. 2020;39:3041-3055 pubmed 出版商
Popp H, Kohl V, Naumann N, Flach J, Brendel S, Kleiner H, et al. DNA Damage and DNA Damage Response in Chronic Myeloid Leukemia. Int J Mol Sci. 2020;21: pubmed 出版商
Belmans N, Gilles L, Vermeesen R, Virag P, Hedesiu M, Salmon B, et al. Quantification of DNA Double Strand Breaks and Oxidation Response in Children and Adults Undergoing Dental CBCT Scan. Sci Rep. 2020;10:2113 pubmed 出版商
Zelensky A, Schoonakker M, Brandsma I, Tijsterman M, van Gent D, Essers J, et al. Low dose ionizing radiation strongly stimulates insertional mutagenesis in a γH2AX dependent manner. PLoS Genet. 2020;16:e1008550 pubmed 出版商
Riancho J, Castanedo Vazquez D, Gil Bea F, Tapia O, Arozamena J, Durán Vían C, et al. ALS-derived fibroblasts exhibit reduced proliferation rate, cytoplasmic TDP-43 aggregation and a higher susceptibility to DNA damage. J Neurol. 2020;267:1291-1299 pubmed 出版商
Current K, Meyer C, Magyar C, Mona C, Almajano J, Slavik R, et al. Investigating PSMA-Targeted Radioligand Therapy Efficacy as a Function of Cellular PSMA Levels and Intratumoral PSMA Heterogeneity. Clin Cancer Res. 2020;26:2946-2955 pubmed 出版商
Janoshazi A, Horton J, Zhao M, Prasad R, Scappini E, Tucker C, et al. Shining light on the response to repair intermediates in DNA of living cells. DNA Repair (Amst). 2020;85:102749 pubmed 出版商
Köse Vogel N, Stengel S, Gardey E, Kirchberger Tolstik T, Reuken P, Stallmach A, et al. Transcriptional Suppression of the NLRP3 Inflammasome and Cytokine Release in Primary Macrophages by Low-Dose Anthracyclines. Cells. 2019;9: pubmed 出版商
Crochemore C, Fernandez Molina C, Montagne B, Salles A, Ricchetti M. CSB promoter downregulation via histone H3 hypoacetylation is an early determinant of replicative senescence. Nat Commun. 2019;10:5576 pubmed 出版商
Santos Barriopedro I, Li Y, Bahl S, Seto E. HDAC8 affects MGMT levels in glioblastoma cell lines via interaction with the proteasome receptor ADRM1. Genes Cancer. 2019;10:119-133 pubmed 出版商
El Daher M, Lemale J, Bruneau J, Leveau C, Guérin F, Lambert N, et al. Chronic Intestinal Pseudo-Obstruction and Lymphoproliferative Syndrome as a Novel Phenotype Associated With Tetratricopeptide Repeat Domain 7A Deficiency. Front Immunol. 2019;10:2592 pubmed 出版商
Henry E, Souissi Sahraoui I, Deynoux M, Lefèvre A, Barroca V, Campalans A, et al. Human hematopoietic stem/progenitor cells display ROS-dependent long-term hematopoietic defects after exposure to low dose of ionizing radiations. Haematologica. 2019;: pubmed 出版商
Scherthan H, Lee J, Maus E, Schumann S, Muhtadi R, Chojowski R, et al. Nanostructure of Clustered DNA Damage in Leukocytes after In-Solution Irradiation with the Alpha Emitter Ra-223. Cancers (Basel). 2019;11: pubmed 出版商
Aguado J, Sola Carvajal A, Cancila V, Revêchon G, Ong P, Jones Weinert C, et al. Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson-Gilford Progeria Syndrome. Nat Commun. 2019;10:4990 pubmed 出版商
Whittemore K, Martinez Nevado E, Blasco M. Slower rates of accumulation of DNA damage in leukocytes correlate with longer lifespans across several species of birds and mammals. Aging (Albany NY). 2019;11:9829-9845 pubmed 出版商
Muñoz Lorente M, Cano Martin A, Blasco M. Mice with hyper-long telomeres show less metabolic aging and longer lifespans. Nat Commun. 2019;10:4723 pubmed 出版商
Yang G, Komaki Y, Yoshida I, Ibuki Y. Formaldehyde inhibits UV-induced phosphorylation of histone H2AX. Toxicol In Vitro. 2019;61:104687 pubmed 出版商
Lu X, Tang M, Zhu Q, Yang Q, Li Z, Bao Y, et al. GLP-catalyzed H4K16me1 promotes 53BP1 recruitment to permit DNA damage repair and cell survival. Nucleic Acids Res. 2019;47:10977-10993 pubmed 出版商
Mason J, Chan Y, Weichselbaum R, Bishop D. Non-enzymatic roles of human RAD51 at stalled replication forks. Nat Commun. 2019;10:4410 pubmed 出版商
Sambeat A, Ratajczak J, Joffraud M, Sánchez García J, Giner M, Valsesia A, et al. Endogenous nicotinamide riboside metabolism protects against diet-induced liver damage. Nat Commun. 2019;10:4291 pubmed 出版商
Zatreanu D, Han Z, Mitter R, Tumini E, Williams H, Gregersen L, et al. Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability. Mol Cell. 2019;76:57-69.e9 pubmed 出版商
Parvin S, Ramírez Labrada A, Aumann S, Lu X, Weich N, Santiago G, et al. LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL. Cancer Cell. 2019;36:237-249.e6 pubmed 出版商
Cameron B, Traver G, Roland J, Brockman A, Dean D, Johnson L, et al. Bcl2-Expressing Quiescent Type B Neural Stem Cells in the Ventricular-Subventricular Zone Are Resistant to Concurrent Temozolomide/X-Irradiation. Stem Cells. 2019;37:1629-1639 pubmed 出版商
Sundaravinayagam D, Rahjouei A, Andreani M, Tupiņa D, Balasubramanian S, Saha T, et al. 53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function. Cell Rep. 2019;28:1389-1399.e6 pubmed 出版商
Hill R, Crossan G. DNA cross-link repair safeguards genomic stability during premeiotic germ cell development. Nat Genet. 2019;51:1283-1294 pubmed 出版商
Fernández Antorán D, Piedrafita G, Murai K, Ong S, Herms A, Frezza C, et al. Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation. Cell Stem Cell. 2019;25:329-341.e6 pubmed 出版商
Jayavaradhan R, Pillis D, Goodman M, Zhang F, Zhang Y, Andreassen P, et al. CRISPR-Cas9 fusion to dominant-negative 53BP1 enhances HDR and inhibits NHEJ specifically at Cas9 target sites. Nat Commun. 2019;10:2866 pubmed 出版商
Brandsma I, Sato K, van Rossum Fikkert S, van Vliet N, Sleddens E, Reuter M, et al. HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis. Cell Rep. 2019;27:3790-3798.e7 pubmed 出版商
Xia Y, Pfeifer C, Zhu K, Irianto J, Liu D, Pannell K, et al. Rescue of DNA damage after constricted migration reveals a mechano-regulated threshold for cell cycle. J Cell Biol. 2019;: pubmed 出版商
Peng J, Tang L, Cai M, Chen H, Wong J, Zhang P. RECQL5 plays an essential role in maintaining genome stability and viability of triple-negative breast cancer cells. Cancer Med. 2019;8:4743-4752 pubmed 出版商
Grill S, Bisht K, Tesmer V, Shami A, Hammoud S, Nandakumar J. Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells. Cell Rep. 2019;27:3511-3521.e7 pubmed 出版商
Liu Y, Efimova E, Ramamurthy A, Kron S. Repair-independent functions of DNA-PKcs protect irradiated cells from mitotic slippage and accelerated senescence. J Cell Sci. 2019;: pubmed 出版商
Smith L, Irianto J, Xia Y, Pfeifer C, Discher D. Constricted migration modulates stem cell differentiation. Mol Biol Cell. 2019;:mbcE19020090 pubmed 出版商
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Ge Y, Wu S, Zhang Z, Li X, Li F, Yan S, et al. Inhibition of p53 and/or AKT as a new therapeutic approach specifically targeting ALT cancers. Protein Cell. 2019;: pubmed 出版商
Cho S, Vashisth M, Abbas A, Majkut S, Vogel K, Xia Y, et al. Mechanosensing by the Lamina Protects against Nuclear Rupture, DNA Damage, and Cell-Cycle Arrest. Dev Cell. 2019;: pubmed 出版商
Campillo Marcos I, Lazo P. Olaparib and ionizing radiation trigger a cooperative DNA-damage repair response that is impaired by depletion of the VRK1 chromatin kinase. J Exp Clin Cancer Res. 2019;38:203 pubmed 出版商
Jung H, Shim Y, Oh J, Oh D, Lee H. The autophagy Protein Atg5 Plays a Crucial Role in the Maintenance and Reconstitution Ability of Hematopoietic Stem Cells. Immune Netw. 2019;19:e12 pubmed 出版商
Huang J, Zhang J, Bellani M, Pokharel D, Gichimu J, James R, et al. Remodeling of Interstrand Crosslink Proximal Replisomes Is Dependent on ATR, FANCM, and FANCD2. Cell Rep. 2019;27:1794-1808.e5 pubmed 出版商
Caron P, Pankotai T, Wiegant W, Tollenaere M, Furst A, Bonhomme C, et al. WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks. Genes Dev. 2019;33:684-704 pubmed 出版商
Lagunas A, FRANCIS M, Maniar N, Nikolova G, Wu J, Crowe D. Paracrine Interaction of Cancer Stem Cell Populations Is Regulated by the Senescence-Associated Secretory Phenotype (SASP). Mol Cancer Res. 2019;: pubmed 出版商
Prieto I, Zambrano A, Laso J, Aranda A, Samper E, Monsalve M. Early induction of senescence and immortalization in PGC-1α-deficient mouse embryonic fibroblasts. Free Radic Biol Med. 2019;138:23-32 pubmed 出版商
Nadeau S, Cheng A, Colmegna I, Rodier F. Quantifying Senescence-Associated Phenotypes in Primary Multipotent Mesenchymal Stromal Cell Cultures. Methods Mol Biol. 2019;: pubmed 出版商
Galindo Campos M, Bedora Faure M, Farrés J, Lescale C, Moreno Lama L, Martinez C, et al. Coordinated signals from the DNA repair enzymes PARP-1 and PARP-2 promotes B-cell development and function. Cell Death Differ. 2019;: pubmed 出版商
Gupta R, Li W, Yan X, Barrientos J, Kolitz J, Allen S, et al. Mechanism for IL-15-Driven B Cell Chronic Lymphocytic Leukemia Cycling: Roles for AKT and STAT5 in Modulating Cyclin D2 and DNA Damage Response Proteins. J Immunol. 2019;202:2924-2944 pubmed 出版商
West K, Kelliher J, Xu Z, An L, Reed M, Eoff R, et al. LC8/DYNLL1 is a 53BP1 effector and regulates checkpoint activation. Nucleic Acids Res. 2019;: pubmed 出版商
Michelini F, Rossiello F, d Adda di Fagagna F, Francia S. RNase A treatment and reconstitution with DNA damage response RNA in living cells as a tool to study the role of non-coding RNA in the formation of DNA damage response foci. Nat Protoc. 2019;14:1489-1508 pubmed 出版商
Miska J, Lee Chang C, Rashidi A, Muroski M, Chang A, Lopez Rosas A, et al. HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma. Cell Rep. 2019;27:226-237.e4 pubmed 出版商
Sekhar K, Wang J, Freeman M, Kirschner A. Radiosensitization by enzalutamide for human prostate cancer is mediated through the DNA damage repair pathway. PLoS ONE. 2019;14:e0214670 pubmed 出版商
Gourzones C, Bellanger C, Lamure S, Gadacha O, de Paco E, Vincent L, et al. Antioxidant Defenses Confer Resistance to High Dose Melphalan in Multiple Myeloma Cells. Cancers (Basel). 2019;11: pubmed 出版商
Li S, Su W, Zhang C. Linear double-stranded DNAs as innovative biological parts to implement genetic circuits in mammalian cells. FEBS J. 2019;286:2341-2354 pubmed 出版商
Belmans N, Gilles L, Virag P, Hedesiu M, Salmon B, Baatout S, et al. Method validation to assess in vivo cellular and subcellular changes in buccal mucosa cells and saliva following CBCT examinations. Dentomaxillofac Radiol. 2019;48:20180428 pubmed 出版商
Schiroli G, Conti A, Ferrari S, Della Volpe L, Jacob A, Albano L, et al. Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response. Cell Stem Cell. 2019;24:551-565.e8 pubmed 出版商
Qin B, Yu J, Nowsheen S, Wang M, Tu X, Liu T, et al. UFL1 promotes histone H4 ufmylation and ATM activation. Nat Commun. 2019;10:1242 pubmed 出版商
Efimova E, Appelbe O, Ricco N, Lee S, Liu Y, Wolfgeher D, et al. O-GlcNAcylation Enhances Double-Strand Break Repair, Promotes Cancer Cell Proliferation, and Prevents Therapy-Induced Senescence in Irradiated Tumors. Mol Cancer Res. 2019;17:1338-1350 pubmed 出版商
Selis D, Pande Y, Smoczer C, Wheater M, Alhabeil J, Paurazas S, et al. Cytotoxicity and Genotoxicity of a New Intracanal Medicament, 2-hydroxyisocaproic Acid-An In Vitro Study. J Endod. 2019;45:578-583 pubmed 出版商
Peng Y, Liao Q, Tan W, Peng C, Hu Z, Chen Y, et al. The deubiquitylating enzyme USP15 regulates homologous recombination repair and cancer cell response to PARP inhibitors. Nat Commun. 2019;10:1224 pubmed 出版商
Linder B, Wehle A, Hehlgans S, Bonn F, Dikic I, Rodel F, et al. Arsenic Trioxide and (-)-Gossypol Synergistically Target Glioma Stem-Like Cells via Inhibition of Hedgehog and Notch Signaling. Cancers (Basel). 2019;11: pubmed 出版商
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产品信息
品牌 :
Novus
SKU号 :
NB100-304
产品名称 :
53BP1抗体
单位尺寸 :
0.025毫升
描述 :
The 53BP1 Antibody from Novus is a rabbit polyclonal antibody to 53BP1. This antibody reacts with human, mouse, rat, bat, bovine, canine, fish, goat, primate. The 53BP1 Antibody has been validated for the following applications: Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Flow (Intracellular), Knockout Validated, Knockdown Validated.
靶标 :
53BP1
类别 :
一抗
缓冲液 :
PBS
克隆性 :
多克隆
浓度 :
1毫克/毫升
共轭标签 :
未共轭
宿主 :
免疫原 :
The epitope recognized by 53BP1 Antibody maps to a region between residues 350 and 400 of human 53BP1 [NP_005648.1].
抗体亚型 :
IgG
纯度 :
免疫原亲和纯化
物种 :
Human, Mouse, Rat, Bat, Bovine, Canine, Fish, Goat, Primate
理论上的分子量 :
214 kDa
基因符号 :
TP53BP1
catalog number base :
NB100-304
应用 :
Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, Immunoblotting, Flow (Intracellular), Knockout Validated, Knockdown Validated
美元 :
149美元
applications abr :
WB, ChIP, Flow, IHC, ICC/IF, IP, IHC-P, IHC-Fr, IB, Flow-IC, KO, KD
别名 :
53BP1, p202, p53-binding protein 1, p53bp1, TDRD30, TP53-Binding Protein 1, tumor protein 53-binding protein, 1, tumor protein p53 binding protein 1, tumor protein p53-binding protein, 1, tumor suppressor p53-binding protein 1
储存 :
存放在-20°C
更多信息或购买 :
公司信息
Novus Biologicals
8100 Southpark Way, A-8
Littleton, CO 80120
technical@novusbio.com
https://www.novusbio.com
1-888-506-6887 303-730-1950
公司总部: 美国
Novus Biologicals的任务是开发最先进的新产品及市场行销来加速生物科研的新发现。藉由高效率的组织分工,Novus Biologicals建立了一个将生物学术团体的成果快速商品化的平台。我们的产品除了附有详细的产品资讯外,Novus Biologicals更提供完整的技术支援及服务。利用快速有效的市场通路以便迅速提供所有的科研学者最先进的研究试剂,Novus Biologicals扮演市场上重要的角色。